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Clearmind Medicine Announces Publication of Six Innovative Patents in Hong Kong for Next-Generation Psychedelic-Based Combination Therapies

(Positive)
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Clearmind Medicine (Nasdaq: CMND) announced publication of six patents in Hong Kong on March 17, 2026 covering proprietary combination therapies that integrate Palmitoylethanolamide (PEA) with six psychedelic compounds.

The patents protect formulations combining PEA with MDMA, LSD, ketamine, ibogaine, psilocybin, and DMT, and reflect a sourcing partnership with NeuroThera Labs. The company describes these combinations as intended to enhance therapeutic potential, safety, tolerability, and neuroplasticity profiles for mental health and neurological indications.

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Positive

  • Publication of 6 patents in Hong Kong on March 17, 2026
  • Patents cover PEA combinations with six psychedelic compounds
  • Declared sourcing partnership with NeuroThera Labs for PEA

Negative

  • Company remains clinical-stage with no approved commercial products
  • IP publication limited to Hong Kong (geographic scope disclosed)

News Market Reaction – CMND

+1.35% 3.5x vol
14 alerts
+1.35% Session close to close
+11.3% Peak Tracked
-24.3% Trough Tracked
$1.31M Market Cap
3.5x Rel. Volume

In the Mar 17 session, CMND gained 1.35%, reflecting a mild positive market reaction. Argus tracked a peak move of +11.3% during that session. Argus tracked a trough of -24.3% from its starting point during tracking. Our momentum scanner triggered 14 alerts that day, indicating notable trading interest and price volatility. Trading volume was very high at 3.5x the daily average, suggesting strong buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement adds six Hong Kong patents covering PEA-based combinations with established psyche...
Analysis

This announcement adds six Hong Kong patents covering PEA-based combinations with established psychedelics, supporting Clearmind’s strategy of building a next‑generation neuroplastogen pipeline. It follows recent IP filings and clinical progress for CMND‑100 in Alcohol Use Disorder and MEAI‑PEA therapies in depression, weight loss, and MASLD. Investors may watch for concrete clinical readouts, revenue‑generating partnerships, and capital-raising steps referenced in recent filings to assess how this expanding IP estate translates into future development milestones.

Key Figures

Hong Kong patents: 6 patents
1 metrics
Hong Kong patents 6 patents Published by Hong Kong Intellectual Property Department

Historical Context

5 past events · Latest: Mar 13 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 13 HK depression patent Positive -5.9% Filed Hong Kong patent for MEAI‑PEA combo targeting major depressive disorder.
Mar 11 Trial cohort enrollment Positive -6.3% Advanced recruitment for CMND‑100 Phase I/IIa Cohort 3 after positive topline data.
Mar 10 Weight loss patent Positive -2.0% Published PCT patent for MEAI‑PEA therapy targeting weight loss and MASLD.
Mar 04 DSMB trial greenlight Positive -4.8% DSMB approved progression to 80 mg Cohort 3 in CMND‑100 AUD trial.
Feb 19 Weight-loss spotlight Positive +4.2% Promotional review highlighting MEAI and GLP‑1-related weight‑loss potential and IP.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent positive clinical and IP developments have often been followed by negative price reactions, suggesting a pattern of selling into good news.

Recent Company History

Over the past month, Clearmind reported multiple positive developments, including DSMB approvals to advance its CMND-100 Phase I/IIa trial and new patent activity in Hong Kong and internationally for MEAI-PEA combination therapies in depression, weight loss, and MASLD. Despite these milestones, the stock frequently declined after such announcements, with four of the last five news events followed by negative moves. Today’s publication of six Hong Kong patents extends this IP-building trend but arrives against a backdrop of persistent price weakness and prior selling into similar news.

Key Terms

palmitoylethanolamide (pea), 3,4-methylenedioxymethamphetamine (mdma), lysergic acid diethylamide (lsd), ketamine, +3 more
7 terms
palmitoylethanolamide (pea) medical
"These patents cover proprietary combination therapies integrating Palmitoylethanolamide (PEA), sourced"
Palmitoylethanolamide (PEA) is a naturally occurring fatty molecule found in the body and some foods that is used in supplements and experimental medicines for its potential to reduce pain and inflammation. Investors care because clinical evidence, regulatory approval, and consumer demand determine whether PEA-based products can become profitable treatments or wellness products, similar to how a promising ingredient can create new market opportunities or face safety and approval hurdles.
3,4-methylenedioxymethamphetamine (mdma) medical
"combining PEA with each of the following: 3,4-Methylenedioxymethamphetamine (MDMA), Lysergic Acid"
A synthetic psychoactive compound that alters mood, empathy and perception and is being investigated for use as a prescription therapy in mental health conditions. Investors watch it because clinical trial results, regulatory decisions and legal scheduling determine whether it can become an approved medicine and a commercial market; think of it like a novel drug candidate whose trial outcomes and legal status will make or break its potential revenue and risk profile.
lysergic acid diethylamide (lsd) medical
"each of the following: 3,4-Methylenedioxymethamphetamine (MDMA), Lysergic Acid Diethylamide (LSD),"
Lysergic acid diethylamide (LSD) is a potent psychoactive compound that alters perception, mood and thought by acting on the brain’s chemistry; think of it as a key that temporarily changes how sensory information and emotions are processed. It matters to investors because clinical research, regulatory decisions, and legal status determine whether LSD-related products can be developed, prescribed, and sold—factors that create potential markets, risks, and valuation swings for companies involved in psychedelic therapies or related industries.
ketamine medical
"Lysergic Acid Diethylamide (LSD), Ketamine, Ibogaine, Psilocybin, and N,N-Dimethyltryptamine (DMT)."
A fast-acting anesthetic drug that is also used at lower doses to treat severe depression and certain pain conditions; it works differently from traditional antidepressants and can produce rapid symptom relief, often described as a short-term “reset” of brain activity. Investors watch ketamine because clinical trial results, regulatory approvals, safety concerns, legal status, production scale, and potential off-label use drive demand, pricing, and the business prospects of companies involved in its manufacture and delivery.
ibogaine medical
"Diethylamide (LSD), Ketamine, Ibogaine, Psilocybin, and N,N-Dimethyltryptamine (DMT)."
A naturally derived psychoactive compound used experimentally to treat substance use disorders and certain mental health conditions; it acts on the brain to reduce cravings and withdrawal symptoms. Investors care because a successful, approved therapy could open a new treatment market, while safety concerns, mixed clinical evidence, and strict regulatory oversight create high development risk—think of it as an experimental key that may unlock value but must pass several safety locks first.
psilocybin medical
"Ketamine, Ibogaine, Psilocybin, and N,N-Dimethyltryptamine (DMT)."
A naturally occurring psychedelic compound found in certain mushrooms that alters perception, mood and consciousness; when taken the body converts it into an active substance that produces short-term hallucinogenic effects. Investors watch psilocybin because researchers and drug developers are exploring it as a potential treatment for depression, PTSD and other mental health conditions, so clinical trial results, regulatory decisions and changing stigma can create large commercial opportunities or risks—think of it as a new drug category whose approval pathway can drive big swings in company value.
n,n-dimethyltryptamine (dmt) medical
"Ibogaine, Psilocybin, and N,N-Dimethyltryptamine (DMT). These novel combinations aim"
n,n-Dimethyltryptamine (DMT) is a naturally occurring chemical that produces short, intense mind‑altering experiences when ingested or inhaled; think of it as a powerful, fast-acting signal that can radically change perception and mood for a brief period. It matters to investors because its legal status, safety profile, and emerging research into therapeutic uses for mental health can create or limit commercial markets, affect regulatory risk, and influence the valuation of companies developing related treatments or products.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Vancouver, Canada, March 17, 2026 (GLOBE NEWSWIRE) -- Clearmind Medicine Inc. (Nasdaq: CMND) (“Clearmind” or the "Company"), a clinical-stage biotech company focused on the discovery and development of novel, non-hallucinogenic, second generation, neuroplastogen-derived therapeutics to solve major under-treated health problems, today announced the publication of six patents by the Intellectual Property Department in Hong Kong. These patents cover proprietary combination therapies integrating Palmitoylethanolamide (PEA), sourced through the Company's partnership with NeuroThera Labs Inc. (TSXV: NTLX), with leading classic and innovative psychedelic compounds.

The published patents protect innovative synergistic formulations combining PEA with each of the following: 3,4-Methylenedioxymethamphetamine (MDMA), Lysergic Acid Diethylamide (LSD), Ketamine, Ibogaine, Psilocybin, and N,N-Dimethyltryptamine (DMT). These novel combinations aim to enhance therapeutic potential while potentially improving safety, tolerability, and neuroplasticity profiles for various mental health and neurological indications.

"We continue to expand our global IP portfolio and taking steps forward in protecting our innovative approach to psychedelic-based combination therapies," said Adi Zuloff-Shani, CEO of Clearmind Medicine. "By strategically combining PEA from our valued partners at NeuroThera with well-characterized psychedelics such as MDMA, LSD, ketamine, ibogaine, psilocybin, and DMT, we continue to build a robust pipeline of next-generation candidates designed to address unmet needs in mental health and beyond.”

About Clearmind Medicine Inc.

Clearmind is a clinical-stage neuroplastogens pharmaceutical biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. Its primary objective is to research and develop psychedelic-based compounds and attempt to commercialize them as regulated medicines, foods, or supplements.

The Company’s intellectual portfolio currently consists of nineteen patent families, including 31 granted patents. The Company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on Nasdaq under the symbol "CMND."

For further information, visit: https://www.clearmindmedicine.com or contact:

Investor Relations
invest@clearmindmedicine.com

Telephone: (604) 260-1566
US: CMND@crescendo-ir.com

General Inquiries
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

Forward-Looking Statements:

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act and other securities laws. Words such as “expects,” “anticipates,” “intends,” “plans,” “believes,” “seeks,” “estimates” and similar expressions or variations of such words are intended to identify forward-looking statements. For example, the Company is using forward-looking statements when it discusses continuing to expand its global IP portfolio and taking steps forward in protecting its innovative approach to psychedelic-based combination therapies and continuing to build a robust pipeline of next-generation candidates designed to address unmet needs in mental health and beyond. The Company cannot assure that any patent will issue as a result of a pending patent application or, if issued, whether it will issue in a form that will be advantageous to the Company. Forward-looking statements are not historical facts, and are based upon management’s current expectations, beliefs and projections, many of which, by their nature, are inherently uncertain. Such expectations, beliefs and projections are expressed in good faith. However, there can be no assurance that management’s expectations, beliefs and projections will be achieved, and actual results may differ materially from what is expressed in or indicated by the forward-looking statements. Forward-looking statements are subject to risks and uncertainties that could cause actual performance or results to differ materially from those expressed in the forward-looking statements. For a more detailed description of the risks and uncertainties affecting the Company, reference is made to the Company’s reports filed from time to time with the Securities and Exchange Commission (“SEC”), including, but not limited to, the risks detailed in the Company’s annual report on Form 20-F for the fiscal year ended October 31, 2025 and subsequent filings with the SEC. Forward-looking statements speak only as of the date the statements are made. The Company assumes no obligation to update forward-looking statements to reflect actual results, subsequent events or circumstances, changes in assumptions or changes in other factors affecting forward-looking information except to the extent required by applicable securities laws. If the Company does update one or more forward-looking statements, no inference should be drawn that the Company will make additional updates with respect thereto or with respect to other forward-looking statements. References and links to websites have been provided as a convenience, and the information contained on such websites is not incorporated by reference into this press release. Clearmind is not responsible for the contents of third-party websites.


FAQ

What patents did Clearmind (CMND) publish on March 17, 2026?

Clearmind published six patents in Hong Kong covering PEA-based combination therapies. According to the company, the patents protect formulations pairing PEA with MDMA, LSD, ketamine, ibogaine, psilocybin, and DMT.

How do the new Clearmind (CMND) patents involve NeuroThera Labs?

The patents rely on PEA sourced via a partnership with NeuroThera Labs. According to the company, NeuroThera supplies PEA used in the proprietary combination formulations described in the patents.

What clinical or commercial impact do Clearmind's (CMND) Hong Kong patents have now?

The patents strengthen Clearmind's IP position but do not confer approvals for products. According to the company, they aim to protect next‑generation candidates' formulations while clinical development continues.

Which psychedelic compounds are covered by Clearmind's (CMND) new patents?

The patents cover PEA combined with MDMA, LSD, ketamine, ibogaine, psilocybin, and DMT. According to the company, each combination is claimed as a distinct synergistic formulation.

Do Clearmind's (CMND) patents guarantee product availability or revenue soon?

No; patent publication does not guarantee near-term commercialization or revenue. According to the company, these patents protect formulations while candidates remain in clinical development and further steps are required before market entry.