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Compass Therapeutics to Announce Topline Secondary Endpoints from the Phase 2/3 COMPANION-002 Study of Tovecimig in Patients with Biliary Tract Cancer

(Very High)

Sentiment and the balance of points

Rhea-AI Sentiment reads the wording of the document, how positive or negative its language is on a 1 to 5 scale. The balance of points shown with the takes weighs what the document actually discloses, so the two can disagree, for example when a trial that missed its main goal is described in upbeat language.

Compass Therapeutics (Nasdaq: CMPX) will host a webcast on Monday, April 27, 2026 at 8:00am ET to review topline secondary endpoints from its Phase 2/3 COMPANION-002 study of tovecimig (a DLL4 x VEGF-A bispecific antibody) plus paclitaxel in advanced biliary tract cancer.

Dial-in numbers and a webcast URL are provided; a replay and accompanying presentation will be available for 90 days on the company’s Investors Events page.

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Argus Apr 27 session
-64.41% close to close Open Argus
Details

News Market Reaction – CMPX

On Apr 27, the first trading day after this news, CMPX closed 64.41% below the previous close.

Data tracked by StockTitan Argus for the Apr 27 session.

Key Figures

Webcast date: April 27, 2026 Webcast time: 8:00am ET Toll-free number: 1-877-407-9716 +3 more
Webcast date
April 27, 2026
COMPANION-002 topline secondary endpoints webcast
Webcast time
8:00am ET
COMPANION-002 topline secondary endpoints webcast
Toll-free number
1-877-407-9716
Investor conference call access
International number
1-201-493-6779
Investor conference call access
Conference ID
13760371
Call-in identifier for webcast
Replay window
90 days
Availability of webcast replay on company website

Previous Clinical trial Reports

2 past events · Latest: Nov 04
Same Type 2 events
  1. Nov 04

    Preclinical data update

    24h Move
    +1.3%

    Presented CTX-10726 preclinical bispecific antibody data at SITC meeting.

  2. Apr 01

    Clinical efficacy result

    24h Move
    +17.9%

    Tovecimig plus paclitaxel met primary ORR endpoint in BTC Phase 2/3 study.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

phase 2/3, bispecific antibody, dll4, vegf-a, +3 more
7 terms
phase 2/3 medical
"topline secondary endpoints from its Phase 2/3 COMPANION-002 clinical study"
A phase 2/3 trial is a combined clinical study that first evaluates how well a treatment works and the best dose, then expands into a larger test to confirm those results and safety. For investors, it matters because moving into a phase 2/3 signals that an experimental therapy has shown initial promise and will be tested at scale, which can materially change the odds and timeline for regulatory approval and commercial potential.
bispecific antibody medical
"tovecimig (a DLL4 x VEGF-A bispecific antibody) in combination with paclitaxel"
A bispecific antibody is a specially designed protein that can attach to two different targets at the same time. Think of it as a custom-made connector that brings two things together—such as a disease cell and an immune system component—helping the body fight illnesses more effectively. For investors, understanding bispecific antibodies is important because they represent innovative therapies that could lead to new treatments and potentially lucrative market opportunities.
dll4 medical
"tovecimig (a DLL4 x VEGF-A bispecific antibody) in combination"
DLL4 is a human signaling protein that helps cells communicate to control blood vessel growth and cell development, acting like a traffic controller that directs where and how blood vessels form. Because drugs that block or modify DLL4 can change a tumor’s blood supply or affect vascular disorders, clinical trial results or regulatory decisions involving DLL4-targeting therapies can materially affect a biotech company’s valuation and commercial prospects.
vegf-a medical
"tovecimig (a DLL4 x VEGF-A bispecific antibody) in combination"
VEGF-A is a naturally occurring protein that acts like a growth signal for new blood vessels, helping tissues develop or repair their blood supply. It matters to investors because many drugs and diagnostics target or measure VEGF-A to treat conditions such as cancers and eye diseases, so changes in clinical trial results, regulatory decisions, or new therapies related to VEGF-A can directly affect the value and prospects of companies developing those treatments.
biliary tract cancer medical
"bispecific antibody) in combination with paclitaxel in patients with advanced biliary tract cancer"
Biliary tract cancer is a group of cancers that start in the bile ducts or gallbladder, the small channels and organ that carry and store the digestive fluid bile; think of it as a clogging, growing problem in a body's plumbing for digestion. For investors, it matters because diagnosis, treatment advances, or clinical trial results can rapidly affect the commercial outlook for drugs, medical devices, and related healthcare companies tied to testing, therapy sales, or reimbursement.
secondary endpoints medical
"to review topline secondary endpoints from its Phase 2/3 COMPANION-002 clinical study"
Secondary endpoints are the additional outcomes measured in a clinical study beyond the main goal; they can include effects on symptoms, quality of life, safety measures, or other health indicators. For investors, they matter because positive or negative secondary results can strengthen or weaken the overall story about a treatment’s benefits and risks—like seeing not only that a car reaches its destination (primary goal) but also how comfortable and efficient the ride was (secondary findings).
paclitaxel medical
"tovecimig ... in combination with paclitaxel in patients with advanced biliary tract cancer"
Paclitaxel is a chemotherapy drug used to treat several types of cancer; it works by binding to and “freezing” the cell’s internal scaffolding so cancer cells cannot divide and grow, much like freezing the rungs of a ladder stops climbers. It matters to investors because clinical trial results, regulatory approvals, manufacturing capacity, patent status and competition from generics or biosimilars directly affect sales, pricing and the financial outlook of companies involved in its development or supply.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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  • Webcast scheduled for Monday, April 27, 2026 at 8:00am ET.

BOSTON, April 24, 2026 (GLOBE NEWSWIRE) -- Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases, announced it will host a webcast on Monday, April 27, 2026 at 8:00am ET to review topline secondary endpoints from its Phase 2/3 COMPANION-002 clinical study assessing tovecimig (a DLL4 x VEGF-A bispecific antibody) in combination with paclitaxel in patients with advanced biliary tract cancer (BTC). 

Conference Call and Webcast Presentation:

Date and Time: Monday, April 27, 2026 at 8:00am ET

Toll Free: 1-877-407-9716

International: 1-201-493-6779

Conference ID: 13760371

Webcast Presentation: https://viavid.webcasts.com/starthere.jsp?ei=1761459&tp_key=efc315f5a6

A replay of the webcast and accompanying presentation will be available, for 90 days, following the event on the “Events” page under the Investors section of the Company’s website.

About Compass Therapeutics
Compass Therapeutics, Inc. was founded in 2014 and is headquartered in Boston, MA. Compass is a clinical-stage, oncology-focused biopharmaceutical company discovering and developing proprietary antibody-based therapeutics to treat multiple diseases. The company’s scientific focus is on the relationship between angiogenesis, the immune system and tumor growth. Compass has a robust pipeline of novel product candidates designed to target multiple key biological pathways to drive an effective anti-tumor response, including angiogenesis modulation, immune activation within the tumor microenvironment, and reduction of tumor-driven immunosuppression. The company is advancing discovery candidates through clinical development to commercial-stage assets. For more information, visit www.compasstherapeutics.com.

Investor Contact
ir@compasstherapeutics.com

Media Contact
Anna Gifford, Chief of Staff
media@compasstherapeutics.com
617-500-8099 


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

When will Compass Therapeutics (CMPX) present topline secondary endpoints from COMPANION-002?

The webcast is scheduled for Monday, April 27, 2026 at 8:00am ET and includes a conference call. According to the company, the session will review topline secondary endpoints from the Phase 2/3 COMPANION-002 study for tovecimig in BTC.

How can investors access the CMPX webcast and presentation on April 27, 2026?

Investors can join via toll-free phone numbers or the webcast URL provided in the announcement. According to the company, international dial-in options and a replay accessible for 90 days are available on the Events page under Investors.

What data will Compass Therapeutics (CMPX) present about tovecimig on April 27, 2026?

The presentation will cover topline secondary endpoints from the Phase 2/3 COMPANION-002 study of tovecimig combined with paclitaxel. According to the company, the study population is patients with advanced biliary tract cancer and uses a DLL4 x VEGF-A bispecific antibody.

Will a replay of the CMPX webcast be available after the April 27, 2026 event?

Yes, a replay and the presentation will be available for 90 days after the webcast on the company’s Investors Events page. According to the company, the replay will be posted following the April 27, 2026 session.

What conference ID and phone numbers should shareholders use to join the CMPX call on April 27, 2026?

Use Conference ID 13760371 to join by phone; toll-free and international numbers are provided for the call. According to the company, toll-free 1-877-407-9716 and international 1-201-493-6779 connect to the April 27, 2026 webcast and conference call.

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