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Cryoport's IntegriCell® Cryopreservation Services Selected by Verismo Therapeutics to Support Clinical KIR-CAR T Cell Therapy Programs

(Positive)
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Cryoport (NASDAQ: CYRX) announced that its IntegriCell® cryopreservation services were selected by Verismo Therapeutics to support clinical KIR-CAR T cell therapy programs SynKIR™-110 and SynKIR™-310.

IntegriCell provides manufacture-ready leukapheresis starting material within a global GMP-compliant system, with service centers in Houston and Liège integrated into Cryoport’s broader temperature-controlled supply chain platform.

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AI-generated analysis. How Rhea-AI works. Not financial advice.

Positive

  • IntegriCell selected to support Verismo’s SynKIR™-110 and SynKIR™-310 clinical programs
  • IntegriCell provides standardized GMP-compliant cryopreserved leukapheresis starting material
  • Cryopreservation centers in Houston and Liège serve Americas and Europe
  • Integration with Cryoport’s broader biologistics, biostorage and informatics platform
  • Strategic alliance with Gulf Coast Regional Blood Center for allogeneic starting materials

Negative

  • None.

News Market Reaction – CYRX

+2.32%
+2.32% News Effect

On the day this news was published, CYRX gained 2.32%, reflecting a moderate positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

What This Means

This announcement expands CYRX’s IntegriCell role across two Phase 1 KIR-CAR programs, reinforcing i...
Analysis

This announcement expands CYRX’s IntegriCell role across two Phase 1 KIR-CAR programs, reinforcing its position in cell and gene therapy logistics. Recent insider net selling and execution on these clinical partnerships remain key factors to monitor.

Key Figures

Phase: Phase 1 Phase: Phase 1 Phase: Phase 1 +1 more
4 metrics
Phase Phase 1 Initial clinical data for SynKIR-110 presented at AACR 2026
Phase Phase 1 SynKIR-110 evaluated in STAR-101 trial for solid tumors
Phase Phase 1 SynKIR-310 evaluated in CELESTIAL-301 trial for B-cell lymphomas
Lead programs 2 programs SynKIR-110 and SynKIR-310 supported by IntegriCell services

Historical Context

5 past events · Latest: May 04 ()
5 events
Date Event Sentiment 24h Move Catalyst
May 04 Quarterly earnings +19.4% Q1 2026 results with raised full-year revenue guidance and CGT growth.
Apr 20 Earnings date notice +0.8% Announcement of timing and access details for Q1 2026 earnings release.
Mar 03 Full-year earnings +2.9% FY2025 results with double-digit revenue growth and 2026 guidance range.
Feb 17 Earnings date notice +1.4% Scheduling update for Q4 and full-year 2025 financial results release.
Feb 11 Product launch -2.3% Launch of MVE Fusion 800 cryogenic freezer for space-constrained settings.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Regulatory & Risk Context

Short Interest: 4.76%
Short Interest
4.76% of float
0% 15% 30%+
low as of 2026-05-29 Days to cover: 2.19

Short interest appears relatively low, suggesting limited short-squeeze potential and a more typical volatility profile driven by fundamentals and news flow rather than heavy bearish positioning.

Key Terms

car t cell therapy, leukapheresis, gmp-compliant, apheresis
4 terms
car t cell therapy medical
"Verismo Therapeutics, a clinical-stage CAR T cell therapy company pioneering"
A therapy that engineers a patient's own immune cells (T cells) so they can recognize and kill cancer cells, like retraining a guard dog to detect a specific scent. It matters to investors because these treatments can be transformative and command high prices, yet require complex manufacturing and face regulatory, safety and reimbursement risks that can greatly influence a biotech or drugmaker’s valuation and future revenue.
leukapheresis medical
"manufacture-ready cryopreserved leukapheresis starting material within a globally"
Leukapheresis is a medical procedure that separates and removes white blood cells from a person’s blood, like running blood through a specialized filter to pull out a specific ingredient. It matters to investors because those collected cells are often the raw material for advanced therapies and clinical trials, so the availability, cost, production speed, and regulation of leukapheresis can directly affect a biotech company’s ability to manufacture treatments and generate revenue.
gmp-compliant technical
"within a globally standardized, GMP-compliant quality management system, IntegriCell"
Good Manufacturing Practice (GMP) compliant means a maker follows established, inspectable rules for producing medicines, medical devices, or other regulated products so each batch is safe, consistent and of expected quality. For investors, GMP compliance lowers the chance of regulatory shutdowns, recalls or delays and increases the likelihood products can be sold; think of it as a verified recipe and checklist that keeps a factory from making faulty batches.
apheresis medical
"donor recruitment and apheresis collection expertise with IntegriCell's"
Apheresis is a medical process that involves removing specific components, such as blood cells or plasma, from a person's bloodstream and then returning the remaining parts back to their body. It is often used to treat health conditions or collect certain blood products for medical use. For investors, understanding apheresis can be relevant when evaluating companies involved in healthcare, biotechnology, or blood-related therapies, as advancements or changes in this technology can impact market opportunities and healthcare costs.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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IntegriCell Provides Process Development, Technology Transfer, and Clinical Cryopreservation Services Supporting Verismo's Novel Multi-chain KIR-CAR Programs for Lead Candidates SynKIR™-110 and SynKIR™-310

NASHVILLE, Tenn., June 25, 2026 /PRNewswire/ -- Cryoport, Inc. (NASDAQ: CYRX) ("Cryoport" or the "Company"), a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, today announced that Cryoport Systems' IntegriCell® cryopreservation services have been selected by Verismo Therapeutics, a clinical-stage CAR T cell therapy company pioneering a novel multi-chain KIR-CAR platform technology for the treatment of solid tumors (SynKIR™-110) and B cell associated disorders and malignancies (SynKIR™-310). Both candidates are in human clinical trials with initial Phase 1 data presented at the American Association for Cancer Research (AACR) 2026 Annual Meeting.

IntegriCell cryopreservation services are designed to support cell and gene therapy programs throughout clinical development and into commercialization. By providing standardized manufacture-ready cryopreserved leukapheresis starting material within a globally standardized, GMP-compliant quality management system, IntegriCell enables developers to reduce variability, improve manufacturing efficiency and derisk their supply chains while delivering the scalable, reproducible solutions required to support global growth.

"Advancing a cell therapy program requires a partner that can help developers refine and scale critical processes as their programs mature," said Dr. Mark Sawicki, CEO, Cryoport Systems. "By implementing Verismo's existing proprietary cryopreservation process within our global quality management system, we enabled them to preserve their existing regulatory work while gaining the consistency and reliability of our bioprocessing, cryopreservation and distribution infrastructure."

"IntegriCell will support cryopreservation for Verismo's two lead clinical programs: SynKIR™-110, currently being evaluated in the STAR-101 Phase 1 trial in patients with advanced mesothelin-expressing solid tumors, and SynKIR™-310, currently being evaluated in the CELESTIAL-301 Phase 1 trial in patients with relapsed or refractory B-cell non-Hodgkin lymphomas," said Bryan Kim, CEO and Co-Founder of Verismo Therapeutics. "Cryopreservation is an important component of the manufacturing process, and having a partner with the expertise to work within our existing workflow is essential. The IntegriCell team implemented our process with precision and worked alongside us to identify opportunities to improve process control and long-term scalability. These improvements position us well as we continue progressing toward future clinical and regulatory milestones to support our novel KIR-CAR platform."

"Cell and gene therapies are advancing rapidly, and the developers driving that progress need reliable supply chain partners who can grow with them," said Jerrell Shelton, CEO, Cryoport. "IntegriCell was built to bring the scientific depth and global infrastructure needed for these programs to succeed. Our partnership with Verismo reflects that commitment, and we look forward to supporting them as their programs continue to advance."

IntegriCell's cryopreservation service centers are strategically located in Houston, Texas and Liège, Belgium, providing geographic coverage to support clinical and commercial programs across the Americas and Europe. IntegriCell's capabilities integrate seamlessly with Cryoport Systems' broader temperature-controlled supply chain platform, spanning biologistics, biostorage and informatics, enabling clients to manage critical materials through a single partner relationship. Cryoport Systems further supports the availability of high-quality allogeneic starting materials through its strategic alliance with Gulf Coast Regional Blood Center, combining donor recruitment and apheresis collection expertise with IntegriCell's cryopreservation capabilities and Cryoport's Cryoshuttle® temperature-controlled transport service.

About Verismo Therapeutics
Verismo Therapeutics, a subsidiary of HLB Innovation, is a pioneer in multi-chain KIR-CAR technology, with assets SynKIR™-110 (NCT05568680) and SynKIR™-310 (NCT06544265) currently in Phase 1 clinical trials. Verismo is the only company developing the KIR-CAR platform, using a modified NK cell-derived receptor and DAP12 pairing, designed to improve T cell functional persistence and reduce exhaustion, resulting in improved efficacy against challenging tumors. The KIR-CAR platform technology was developed specifically to address areas of high unmet medical need, including advanced solid tumors and B cell associated disorders and malignancies. For more information, visit: www.verismotherapeutics.com

About Cryoport, Inc.
Cryoport, Inc. (Nasdaq: CYRX) is a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, with an emphasis on regenerative medicine. We support biopharmaceutical companies, contract manufacturers (CDMOs), contract research organizations (CROs), developers, and researchers with a comprehensive suite of services and products designed to minimize risk and maximize reliability across the temperature-controlled supply chain for the life sciences. Our integrated supply chain platform includes the Cryoportal® Logistics Management Platform, advanced temperature-controlled packaging, informatics, specialized BioLogistics, biostorage, BioServices, cryopreservation services, and cryogenic systems, which in varying combinations deliver end-to-end solutions that meet the rigorous demands of the life sciences. With innovation, regulatory compliance, and agility at our core, we are "Enabling the Future of Medicine™."

Headquartered in Nashville, Tennessee, our company maintains a strong global presence with operations across the Americas, EMEA, and APAC.

For more information, visit www.cryoportinc.com or follow via LinkedIn at https://www.linkedin.com/company/cryoportinc or @cryoport on X, formerly known as Twitter at https://x.com/cryoport for live updates.

Forward-Looking Statements
Statements in this press release which are not purely historical, including statements regarding Cryoport's intentions, hopes, beliefs, expectations, representations, projections, plans or predictions of the future, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. It is important to note that Cryoport's actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, risks and uncertainties associated with the effect of changing economic and geopolitical conditions, supply chain constraints, inflationary pressures, the effects of foreign currency fluctuations, trends in the products markets, variations in Cryoport's cash flow, market acceptance risks, and technical development risks. Cryoport's business could be affected by other factors discussed in Cryoport's SEC reports, including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC. The forward-looking statements contained in this press release speak only as of the date hereof and Cryoport cautions investors not to place undue reliance on these forward-looking statements. Except as required by law, Cryoport disclaims any obligation, and does not undertake to update or revise any forward-looking statements in this press release

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/cryoports-integricell-cryopreservation-services-selected-by-verismo-therapeutics-to-support-clinical-kir-car-t-cell-therapy-programs-302810192.html

SOURCE Cryoport, Inc.

FAQ

What did Cryoport (NASDAQ: CYRX) announce on June 25, 2026 about Verismo Therapeutics?

Cryoport announced that Verismo Therapeutics selected its IntegriCell® cryopreservation services to support SynKIR™-110 and SynKIR™-310 clinical KIR-CAR T cell programs. According to Cryoport, IntegriCell will provide standardized, manufacture-ready leukapheresis starting material within a globally standardized, GMP-compliant quality management system.

What is IntegriCell® and how does it support Cryoport (CYRX) cell and gene therapy clients?

IntegriCell® is Cryoport’s cryopreservation service offering process development, technology transfer and clinical cryopreservation for cell and gene therapy programs. According to Cryoport, it delivers manufacture-ready cryopreserved leukapheresis material, aiming to reduce variability, improve manufacturing efficiency and help derisk supply chains from clinical development through commercialization.

Which Verismo SynKIR programs are supported by Cryoport’s IntegriCell® services?

IntegriCell® supports Verismo’s SynKIR™-110 and SynKIR™-310 lead clinical programs. According to Cryoport, SynKIR™-110 is in the STAR-101 Phase 1 trial for advanced mesothelin-expressing solid tumors, while SynKIR™-310 is in CELESTIAL-301 for relapsed or refractory B-cell non-Hodgkin lymphomas.

Where are Cryoport’s IntegriCell® cryopreservation service centers located and what regions do they serve?

Cryoport’s IntegriCell® cryopreservation service centers are located in Houston, Texas and Liège, Belgium. According to Cryoport, these locations provide geographic coverage to support clinical and commercial cell and gene therapy programs across the Americas and Europe within a globally standardized quality framework.

How does Cryoport (CYRX) integrate IntegriCell® with its broader supply chain platform?

Cryoport integrates IntegriCell® capabilities with its broader temperature-controlled supply chain platform. According to Cryoport, this platform spans biologistics, biostorage and informatics, enabling clients to manage critical starting materials and therapies through a single partner for cryopreservation, storage, and transport.

What role does Gulf Coast Regional Blood Center play in Cryoport’s IntegriCell® offering?

Gulf Coast Regional Blood Center supports Cryoport by enhancing access to high-quality allogeneic starting materials. According to Cryoport, a strategic alliance combines donor recruitment and apheresis collection with IntegriCell’s cryopreservation and Cryoshuttle® temperature-controlled transport, supporting cell and gene therapy supply chains.