Dyne Therapeutics Announces Proposed Public Offering of Common Stock
Rhea-AI Summary
Dyne Therapeutics (Nasdaq: DYN) announced on Dec 8, 2025 that it commenced an underwritten public offering of $300,000,000 of common stock with a 30-day option for underwriters to purchase up to an additional $45,000,000 of shares.
All shares in the proposed offering are to be sold by Dyne. The offering is subject to market and other conditions and will be made pursuant to a Form S-3 shelf registration filed on March 5, 2024. Morgan Stanley, Jefferies, Stifel and Guggenheim Securities are joint book-running managers. A preliminary prospectus supplement is expected to be filed with the SEC and final terms will appear in a final prospectus supplement.
Positive
- Primary raise of $300,000,000 announced
- Up to $345,000,000 available including underwriter option
Negative
- All offered shares are company shares, implying shareholder dilution
- Offering completion is conditional on market and other factors
Key Figures
Market Reality Check
Peers on Argus
Peers show mixed moves: SRPT -2.73%, IMCR -3.22%, PROK -8.95%, while MESO +1.77% and HRMY +4.08%. DYN’s pre‑news decline of 2.27% appears more stock‑specific around the offering.
Historical Context
| Date | Event | Sentiment | Move | Catalyst |
|---|---|---|---|---|
| Nov 05 | Earnings and update | Neutral | -2.9% | Quarterly results and pipeline timelines, including DELIVER and ACHIEVE updates. |
| Nov 03 | Investor conferences | Positive | +6.8% | Multiple upcoming healthcare conference presentations and webcasts announced. |
| Oct 06 | Clinical data update | Positive | -3.1% | One‑year Phase 1/2 ACHIEVE data showing functional improvement in DM1. |
| Oct 02 | Board appointment | Positive | +4.1% | Appointment of experienced executive Brian Posner to the Board of Directors. |
| Sep 29 | Regulatory designation | Positive | -5.9% | Japanese Orphan Drug designation for DYNE‑251 with potential 10‑year exclusivity. |
Recent history shows occasional sell‑offs on positive clinical and regulatory milestones, and modest pressure around financing events.
Over the last few months, Dyne reported Q3 2025 results with cash of $791.9M and an expected runway into Q3 2027, alongside multiple Breakthrough Therapy Designations. It has highlighted key upcoming data in DELIVER and ACHIEVE and added an experienced director as it prepares for potential launches around 2027–2028. Clinical updates for DYNE‑101 and DYNE‑251 have been generally positive, though share reactions have sometimes been negative. Today’s proposed offering follows prior 2025 financings that strengthened liquidity.
Market Pulse Summary
This announcement details a proposed underwritten public offering of $300,000,000 of Dyne’s common stock, with a 30‑day option for underwriters to purchase up to an additional $45,000,000. It follows earlier 2025 equity financings that bolstered liquidity as the company advances DYNE‑251 and DYNE‑101 toward key data and potential filings. Investors may watch for the final prospectus terms, total capital raised, and how this fits with the cash runway already disclosed in recent SEC filings.
Key Terms
underwritten public offering financial
prospectus supplement regulatory
registration statement regulatory
form s-3 regulatory
AI-generated analysis. Not financial advice.
WALTHAM, Mass., Dec. 08, 2025 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (Nasdaq: DYN), a clinical-stage company focused on delivering functional improvement for people living with genetically driven neuromuscular diseases, today announced that it has commenced an underwritten public offering of
Morgan Stanley, Jefferies, Stifel and Guggenheim Securities are acting as joint book-running managers for the offering. The proposed offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.
The proposed offering is being made pursuant to a shelf registration statement on Form S-3 that was previously filed with the Securities and Exchange Commission (“SEC”) on March 5, 2024 and became automatically effective upon filing. This offering will be made only by means of a prospectus supplement and accompanying prospectus that form a part of the registration statement. A preliminary prospectus supplement relating to and describing the terms of the offering is expected to be filed with the SEC and, if and when filed, copies of the preliminary prospectus supplement relating to the offering may be obtained for free by visiting the SEC’s website at www.sec.gov. Copies of the preliminary prospectus supplement and the accompanying prospectus may also be obtained by contacting: Morgan Stanley & Co. LLC, Attention: Prospectus Department, 180 Varick Street, 2nd Floor, New York, NY 10014, or by email at prospectus@morganstanley.com; Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, New York, NY 10022, by telephone at (877) 821-7388, or by email at Prospectus_Department@Jefferies.com; Stifel, Nicolaus & Company, Incorporated, Attention: Prospectus Department, One Montgomery Street, Suite 3700, San Francisco, CA 94104, by telephone at (415) 364-2720 or by email at syndprospectus@stifel.com; or Guggenheim Securities, LLC, Attention: Equity Syndicate Department, 330 Madison Avenue, 8th Floor, New York, NY 10017, by telephone at (212) 518-9544, or by email at GSEquityProspectusDelivery@guggenheimpartners.com. The final terms of the offering will be disclosed in a final prospectus supplement to be filed with the SEC.
This press release shall not constitute an offer to sell, or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.
About Dyne Therapeutics
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities.
Forward-Looking Statements
This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this press release, including statements relating to the proposed underwritten public offering, the anticipated terms of the proposed offering, market and other conditions relating to the offering, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “objective,” “ongoing,” “plan,” “predict,” “project,” “potential,” “should,” or “would,” or the negative of these terms, or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Dyne may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various important factors, including: the uncertainties related to market conditions and the completion of the public offering on the anticipated terms or at all and other factors discussed in the “Risk Factors” section of the preliminary prospectus supplement to be filed with the SEC, as well as the risks and uncertainties identified in Dyne’s filings with the SEC, including Dyne’s most recent Form 10-Q and in subsequent filings Dyne may make with the SEC. In addition, the forward-looking statements included in this press release represent Dyne’s views as of the date of this press release. Dyne anticipates that subsequent events and developments will cause its views to change. However, while Dyne may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Dyne’s views as of any date subsequent to the date of this press release.
Contacts:
Investors
Mia Tobias
ir@dyne-tx.com
781-317-0353
Media
Stacy Nartker
snartker@dyne-tx.com
781-317-1938