Eikon Therapeutics Reports Third Quarter 2026 Financial Results and Provides Clinical Updates

Eikon expects its cash to fund operations into the first quarter of 2028, through anticipated clinical milestones in 2027.

Rhea-AI Summary

Eikon Therapeutics (Nasdaq: EIKN) reported a third-quarter 2026 net loss attributable to common stockholders of $86.1 million alongside oncology trial updates. The loss widened from $71.1 million a year earlier, while loss per share narrowed to $1.59 from $24.24. Research and development expenses rose 21% to $71.8 million; general and administrative expenses increased 21% to $18.7 million.

Cash, cash equivalents and marketable securities totaled $461.7 million at September 30. Eikon expects funding to last into the first quarter of 2028. In the ongoing Phase 2 TeLuRide-005 lung cancer trial, EIK1001 with pembrolizumab and chemotherapy produced a 63.1% objective response rate among 65 efficacy-evaluable participants. Eikon also dosed the first patient in registrational trial TeLuRide-008, reported early-stage results for other oncology candidates and submitted an application to begin clinical testing of EIK1006.

26 points · 0 major

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1 major · 7 points

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Positive

• Moderate pointCash, cash equivalents and marketable securities increased to $461.717 million from $335.975 million at December 31, 2025.
• Moderate point. Forward-looking: it has not happened yet and may not happen.Updated funding guidance anticipates operations funded into the first quarter of 2028.
• Moderate pointNine-month general and administrative expenses fell to $53.950 million from $70.688 million a year earlier.
• Moderate pointStockholders’ equity reached $384.293 million, versus an $879.034 million deficit at December 31, 2025.
• Moderate pointTeLuRide-005 pooled results showed 63.1% objective response and 89.2% disease control among 65 efficacy-evaluable participants.
• Moderate pointTeLuRide-008 dosed its first patient; the registrational Phase 2/3 lung cancer trial is actively enrolling.

20 minor points

• Minor pointQuarterly loss per share narrowed to $1.59 from $24.24, with weighted-average shares increasing to 54,168,268 from 2,934,921.
• Minor pointQuarterly net interest income increased to $4.486 million from $3.613 million a year earlier.
• Minor pointTeLuRide-005 squamous cohort achieved 72.4% response, 100% disease control and 12.9-month median response duration.
• Minor pointTeLuRide-005 non-squamous cohort achieved 55.6% response, 80.6% disease control and 11.2-month median response duration.
• Minor pointEIK1001 combination was generally well-tolerated, with an adverse event profile similar to standard-of-care alone.
• Minor point. Forward-looking: it has not happened yet and may not happen.Eikon anticipates EIK1001 melanoma advancement analysis in first-half 2027 and lung cancer dose-selection analysis in second-half 2027.
• Minor pointEIK1003 monotherapy showed 14.3% response among 49 efficacy-evaluable participants and 31.3% among PARP inhibitor-naïve participants.
• Minor pointEIK1003 plus abiraterone showed 20.8% response among 24 evaluable participants; 30.8% of PSA-evaluable participants had ≥50% PSA reductions.
• Minor pointEIK1003 plus paclitaxel showed 26.4% response among 53 efficacy-evaluable participants, including one complete and 13 partial responses.
• Minor pointEIK1003 monotherapy was generally well-tolerated; the abiraterone combination showed a favorable tolerability profile.
• Minor point. Forward-looking: it has not happened yet and may not happen.Eikon expects EIK1003 chemotherapy-combination initial results and completion of Phase 2 dose optimization in second-half 2027.
• Minor pointEIK1004 showed 12.1% response and 62.1% disease control among 58 efficacy-evaluable participants.
• Minor pointEIK1004 was generally well-tolerated, with minimal blood-related toxicity across multiple dose levels.
• Minor point. Forward-looking: it has not happened yet and may not happen.Eikon plans an EIK1004–docetaxel combination arm, with initial results expected in second-half 2027.
• Minor pointPreliminary EIK1005 monotherapy findings showed stable disease in 6 of 8 efficacy-evaluable participants.
• Minor pointEIK1005’s first pembrolizumab-combination participant achieved a partial response at the first post-baseline scan.
• Minor pointEIK1005 was generally well tolerated, with drug-exposure findings supporting once-weekly administration.
• Minor point. Forward-looking: it has not happened yet and may not happen.Eikon expects EIK1005 combination results in first-half 2027 and complete monotherapy results in second-half 2027.
• Minor pointEIK1006 investigational drug application was submitted October 14, 2026 for advanced metastatic prostate cancer.
• Minor point. Forward-looking: it has not happened yet and may not happen.Eikon plans EIK1006 Phase 1/2 testing, with preliminary safety and efficacy data anticipated in second-half 2027.

Negative

• Major pointQuarterly net loss attributable to common stockholders widened to $86.112 million from $71.139 million a year earlier.
• Moderate pointOperating activities used $224.0 million in cash during the nine months ended September 30, 2026.
• Moderate pointQuarterly research and development expenses increased 21% to $71.8 million from $59.3 million a year earlier.
• Minor pointQuarterly general and administrative expenses increased 21% to $18.7 million from $15.4 million a year earlier.
• Minor pointNine-month research and development expenses rose to $217.333 million from $185.089 million a year earlier.

2 minor points

• Minor pointNine-month net loss attributable to common stockholders widened to $257.479 million from $253.989 million a year earlier.
• Minor pointEIK1006 clinical trial initiation remains subject to FDA clearance.

News Explained

Eikon says the TeLuRide-008 Phase 2/3 trial is actively enrolling, with its prespecified interim analysis for dose selection expected in the second half of 2027, setting out the next stated milestone for the program.

Key Figures

Cash, cash equivalents and marketable securities: $461.7 million Cash runway: Into the first quarter of 2028 Net cash used in operating activities: $224.0 million +5 more

Cash, cash equivalents and marketable securities

$461.7 million

As of September 30, 2026

Cash runway

Into the first quarter of 2028

Company guidance

Net cash used in operating activities

$224.0 million

Nine months ended September 30, 2026

Net loss attributable to common stockholders

$86.1 million

Third quarter 2026; compared with $71.1 million in the prior-year period

Research and development expenses

$71.8 million; up 21%

Three months ended September 30, 2026, compared with the same period in 2025

Objective response rate

63.1%

TeLuRide-005 pooled efficacy-evaluable population (n=65)

Disease control rate

89.2%

TeLuRide-005 pooled efficacy-evaluable population (n=65)

Median duration of response

12.9 months

TeLuRide-005 squamous cohort

Previous Earnings Reports

1 past event · Latest: Aug 13

Same Type 1 event

1. Aug 13

   2Q26 earnings

   24h Move

   +7.0%

   Reported $531.2 million in cash and runway into the second half of 2027.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

objective response rate, disease control rate, pharmacokinetic profile, investigational new drug (ind) application, +1 more

5 terms

objective response rate medical

"an objective response rate (ORR) of 63.1%"

The objective response rate (ORR) is the percentage of patients in a clinical trial whose tumors measurably shrink or disappear according to preset rules. Investors use it as a quick, objective signal of a drug’s ability to produce a clear treatment effect—like counting how many plants visibly respond after applying a new fertilizer—and higher ORR can improve odds of regulatory approval, commercial success, and company valuation.

disease control rate medical

"disease control rate (DCR) of 89.2%"

The disease control rate is the share of patients in a clinical trial whose cancer or condition either shrinks or stops getting worse for a specified period after treatment. Think of it like the percentage of people for whom a treatment hits pause or nudges back the problem rather than letting it progress; higher rates suggest the therapy can meaningfully limit disease, which matters to investors assessing a drug’s potential efficacy and commercial value.

pharmacokinetic profile medical

"demonstrated a pharmacokinetic profile supporting once-weekly administration"

The pharmacokinetic profile describes how a drug moves through the body over time, including how quickly it is absorbed, how it spreads, and how it is eventually eliminated. For investors, understanding this profile helps gauge the drug’s effectiveness, safety, and the appropriate dosing schedule, which can influence a company’s potential success and market value. It provides insight into how a medication behaves, impacting its overall commercial viability.

investigational new drug (ind) application regulatory

"submitted an IND application to the U.S. Food and Drug Administration"

An investigational new drug (IND) application is a formal request submitted to a drug regulator asking permission to begin testing a new medicine in people. It compiles lab results, manufacturing details and proposed human trial plans so regulators can judge safety before human studies start; for investors, an accepted IND is a key milestone that opens the clinical development pathway and can materially change a company’s risk profile and potential value, like getting a license to road-test a prototype.

microsatellite instability-high medical

"for microsatellite instability-high (MSI-high) tumors"

Microsatellite instability-high (MSI-high) describes a tumor characteristic where the cell’s DNA error-correction system is broken, so short repeated DNA sequences accumulate many mistakes—like a spellchecker failing and leaving lots of typos. Investors care because MSI-high cancers often respond differently to certain therapies, shape clinical trial eligibility and regulatory decisions, and can influence a drug’s market opportunity and valuation.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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• Presented seven posters at the 2026 European Society for Medical Oncology (ESMO) Congress highlighting progress across the oncology portfolio, including clinical data from Eikon’s PARP1-selective inhibitor and Werner (WRN) helicase inhibitor programs and updated EIK1001 data from TeLuRide-005, a Phase 2 trial in non-small cell lung cancer (NSCLC)
  
  
• Dosed first patient in TeLuRide-008, a registrational Phase 2/3 trial of EIK1001 in combination with pembrolizumab and chemotherapy in NSCLC
  
  
• Submitted an Investigational New Drug (IND) application for EIK1006, a novel non-lutamide androgen receptor (AR) antagonist with broad activity against wild type and AR variants associated with treatment failure in patients with prostate cancer
  
  
• Appointed Ching-Pin Chang, M.D., Ph.D., as Chief Scientific Officer
  
  
• Ended third quarter 2026 with $461.7 million in cash, cash equivalents and marketable securities; updating runway guidance into the first quarter of 2028 based on continued fiscal discipline and operating leverage
  
  

MILLBRAE, Calif., Nov. 12, 2026 (GLOBE NEWSWIRE) -- Eikon Therapeutics, Inc. (Nasdaq: EIKN) (Eikon), a late-stage clinical biopharmaceutical company dedicated to developing innovative medicines to address serious unmet medical needs, today reported third quarter 2026 financial results and provided updates on its programs.

“The third quarter was marked by important progress across Eikon’s oncology programs,” said Roger M. Perlmutter, M.D., Ph.D., Chief Executive Officer and Board Chair of Eikon. “At the 2026 ESMO Congress, we presented updated results from TeLuRide-005, providing additional evidence of durable anti-tumor activity for EIK1001 in combination with standard-of-care therapy in squamous NSCLC, building on earlier data in non-squamous NSCLC that we shared at ASCO. We also presented encouraging activity and tolerability data across our selective PARP1 inhibitor programs, supporting their continued development, alongside initial findings from our WRN inhibitor program. Taken together, these findings demonstrate the breadth of our clinical portfolio and reflect our broader mission at Eikon to translate rigorous science into innovative medicines with the potential to address important unmet needs in cancer therapy.”

Clinical Development Highlights

EIK1001

EIK1001 is a systemically administered TLR 7/8 dual-agonist designed to stimulate both innate and adaptive immune responses to malignancy. Intravenous administration of EIK1001 has been observed to be generally well-tolerated, shown a pharmacodynamic profile consistent with systemic immune responses, and can be combined with current standard-of-care.

• On October 26, 2026, Eikon presented updated data at the 2026 ESMO Congress from TeLuRide-005 (NCT06246110), an ongoing open-label Phase 2 trial evaluating the safety and tolerability of EIK1001 in combination with both pembrolizumab and histology-appropriate chemotherapy for the treatment of patients with NSCLC. Among other results, the presentation showed:
  • Across the pooled efficacy-evaluable population (n=65), EIK1001 in combination with pembrolizumab and chemotherapy resulted in an objective response rate (ORR) of 63.1% and disease control rate (DCR) of 89.2% at a median follow-up of 17.2 months, with objective responses observed across all PD-L1 tumor proportion score (TPS) subgroups.
  • In the squamous cohort, ORR was 72.4% and DCR was 100%, with a median duration of response (DOR) of 12.9 months at a median follow-up of 12.7 months.
  • In the non-squamous cohort, ORR was 55.6% and DCR was 80.6%, with a median DOR of 11.2 months at a median follow-up of 17.9 months.
  • The combination was generally well-tolerated, with an adverse event profile similar to standard-of-care alone and a tolerability profile supportive of systemic administration of EIK1001 in an outpatient setting.
• On July 27, 2026, Eikon announced dosing of the first patient in TeLuRide-008 (NCT07365319), a Phase 2/3 registrational trial evaluating EIK1001 in combination with pembrolizumab and histology-appropriate chemotherapy as first-line therapy for treatment-naïve patients with stage 4 NSCLC. The trial is actively enrolling, with a prespecified interim analysis for dose selection anticipated in the second half of 2027.

EIK1003 & EIK1004

EIK1003 and EIK1004 are highly selective PARP1 inhibitors designed to inhibit PARP1 while sparing PARP2, thereby promoting tumor regression by targeting the DNA damage response of cancer cells. EIK1004 was specifically engineered to penetrate the central nervous system (CNS), potentially expanding the utility of selective PARP1 inhibition to tumors involving the brain. The selectivity of EIK1003 and EIK1004 may enable the development of near full-dose combination regimens with chemotherapy, antibody-drug conjugates, or radionuclides, in earlier lines of therapy than currently possible with non-selective PARP inhibitors, and potentially allow for more sustained therapeutic dosing during maintenance treatment.

• On October 23, 2026, Eikon presented updated and initial clinical data at the 2026 ESMO Congress from its ongoing Phase 1/2 trial evaluating EIK1003 as a monotherapy and in combination with anti-cancer agents in participants with advanced solid tumors (NCT06253130). Among other results, the presentations showed:
  • In Cohort 1A, evaluating EIK1003 monotherapy, EIK1003 was generally well-tolerated across multiple dose levels. Among 49 efficacy-evaluable participants, the ORR was 14.3% overall and 31.3% among PARP inhibitor-naïve participants.
  • In Cohort 1B, evaluating EIK1003 in combination with abiraterone in patients with metastatic prostate cancer, the combination demonstrated a favorable tolerability profile and preliminary anti-tumor activity, including an ORR of 20.8% among 24 RECIST-evaluable participants and a prostate-specific antigen (PSA) response (greater than or equal to 50% from baseline) in 30.8% of PSA-evaluable participants.
  • In Cohort 1C, evaluating EIK1003 in combination with weekly paclitaxel in patients with ovarian or breast cancer that had failed appropriate therapy, signals of anti-tumor activity were observed, with an ORR of 26.4% among 53 efficacy-evaluable participants, including one confirmed complete response and 13 partial responses, and with 86% of responders having had prior taxane exposure.
• On October 23, 2026, Eikon also presented initial clinical data at the 2026 ESMO Congress from its ongoing Phase 1/2 trial evaluating EIK1004 (NCT06907043). EIK1004 was generally well-tolerated, with minimal hematologic toxicity, across multiple dose levels. Among 58 efficacy-evaluable participants, ORR was 12.1% and DCR was 62.1%, with responses observed in breast, ovarian and prostate cancers.
  
  

EIK1005

EIK1005 is a novel molecular entity, designed to inhibit the Werner (WRN) helicase, that emerged from original research conducted in Eikon’s laboratories. EIK1005 has the potential to be an effective anti-tumor agent for microsatellite instability-high (MSI-high) tumors by producing synthetic lethality in MSI-high cells that depend upon the WRN helicase salvage pathway to maintain genome integrity.

• On October 23, 2026, Eikon presented preliminary clinical data at the 2026 ESMO Congress from EIK1005-002, an ongoing Phase 1/2 trial evaluating EIK1005 as monotherapy and in combination with pembrolizumab in participants with advanced solid tumors (NCT07262619). Among other results, the presentation showed:
  • EIK1005 was generally well tolerated and demonstrated a pharmacokinetic profile supporting once-weekly administration.
  • 6 of 8 efficacy-evaluable participants in the monotherapy dose-escalation portion achieved stable disease (SD), all of whom had confirmed DNA mismatch repair deficiency (dMMR) or MSI-high tumors.
  • The first participant enrolled in the combination dose-escalation portion with pembrolizumab achieved a partial response at the first post-baseline scan.

EIK1006

EIK1006 is an internally-derived clinical candidate and is being investigated as a potential next-generation androgen receptor (AR) antagonist with activity against wild type and multiple clinically important genetic variants of AR that emerge during treatment with conventional AR antagonists. Preclinically, Eikon scientists have shown that EIK1006 binds to the ligand binding domain of AR and blocks its nuclear translocation, thereby inhibiting AR transcriptional activity and downstream signaling.

• On October 14, 2026, Eikon submitted an IND application to the U.S. Food and Drug Administration (FDA) to evaluate EIK1006 for the treatment of advanced metastatic prostate cancer.
  
  

Key Upcoming Milestones

• EIK1001: Prespecified interim analysis for advancement to Phase 3 for TeLuRide-006, a registrational Phase 2/3 trial of EIK1001 in combination with pembrolizumab in advanced melanoma, is anticipated in the first half of 2027, and prespecified interim analysis for dose selection in the ongoing TeLuRide-008 Phase 2/3 trial of EIK1001 in combination with pembrolizumab and histology-appropriate chemotherapy as first-line treatment for patients with stage 4 NSCLC is anticipated in the second half of 2027.
• EIK1003: Eikon expects initial results from Cohort 1D of the ongoing Phase 1/2 study evaluating EIK1003 in combination with paclitaxel and platinum-based chemotherapy in the second half of 2027, and expects to complete the ongoing Phase 2 dose-optimization portion of the EIK1003 trial in the second half of 2027.
• EIK1004: Eikon plans to initiate a combination arm in the Phase 1/2 study to evaluate EIK1004 with docetaxel in patients with castrate-resistant prostate cancer and expects to report initial results from that combination arm in the second half of 2027.
• EIK1005: Eikon expects additional results from the Phase 1/2 study evaluating EIK1005 in combination with pembrolizumab in the first half of 2027 and complete results from the EIK1005 monotherapy portion of the trial in the second half of 2027.
• EIK1006: Subject to FDA clearance, Eikon plans to initiate a Phase 1/2 study in metastatic prostate cancer and anticipates preliminary safety and efficacy data to be available in the second half of 2027.
  
  

Third Quarter 2026 Corporate Highlights

Appointment of Ching-Pin (CP) Chang, M.D., Ph.D., as Executive Vice President and Chief Scientific Officer

On September 3, 2026, Eikon appointed Ching-Pin “CP” Chang, M.D., Ph.D., as Executive Vice President and Chief Scientific Officer. Dr. Chang is a physician-scientist with more than two decades of experience spanning academic medicine, fundamental research and drug discovery. He joined Eikon from Bristol Myers Squibb, where he most recently served as Vice President, Head of Cardiovascular Discovery Biology and Translational Pharmacology. Previously, he served in research leadership roles at Gilead Sciences, at MyoKardia and held academic positions at Stanford University and at the Indiana University School of Medicine.

Third Quarter 2026 Financial Results

Cash Position: As of September 30, 2026, Eikon had cash, cash equivalents, and marketable securities of $461.7 million. Net cash used in operating activities was $224.0 million for the nine months ended September 30, 2026. Eikon expects its current cash, cash equivalents, and marketable securities to fund operations into the first quarter of 2028.

Research and Development (R&D) Expenses: R&D expenses were $71.8 million for the three months ended September 30, 2026 compared to $59.3 million for the three months ended September 30, 2025, an increase of $12.5 million, or 21%. Direct research and development expenses increased $9.2 million as we advanced our clinical trial activity, and compensation costs increased $3.0 million.

General and Administrative (G&A) Expenses: G&A expenses were $18.7 million for the three months ended September 30, 2026, compared to $15.4 million for the three months ended September 30, 2025, an increase of $3.3 million, or 21%. This increase was primarily due to $1.5 million higher professional fees from consulting and legal expenses and $1.1 million higher other operating expenses, primarily IT expenses.

Net Loss: Net loss attributable to common stockholders was $86.1 million for the third quarter of 2026, as compared to $71.1 million for the prior-year period.

“We ended the third quarter with $461.7 million in cash and are updating our runway guidance into the first quarter of 2028, through the key clinical milestones anticipated in 2027,” said Freddie Bowie, Ph.D., Chief Financial Officer. “We have remained focused on disciplined capital allocation. Operating expenses for the nine months ended September 30, 2026 increased 6% year over year, with G&A down 24% and R&D representing 80% of the total. We are concentrating investment behind our most advanced programs and tying incremental spending to clinical milestones, with the goal of creating long-term shareholder value.”

About Eikon Therapeutics
Eikon is a late-stage clinical biopharmaceutical company dedicated to building a global, fully integrated organization developing innovative medicines to address serious unmet medical needs. Eikon’s initial focus is oncology, where it is advancing a pipeline of drug candidates targeting areas of high unmet need that could eventually become critical medicines for the treatment of various cancers. Eikon deploys its technology platform, including its proprietary single molecule tracking system, to develop internally derived novel therapies, while also leveraging the deep expertise of its management team to in-license promising assets. Eikon’s vision is to become a generational leader, by purposefully integrating traditional biology research with advanced engineering to develop better medicines faster. For more information, visit www.eikontx.com.

Forward-Looking/Safe Harbor Statements
This press release contains forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. All statements in this press release that are not historical facts are hereby identified as forward-looking statements for this purpose. These statements may be identified by words such as “aims,” “anticipates,” “believes,” “could,” “estimates,” “expects,” “forecasts,” “goal,” “intends,” “may,” “plans,” “possible,” “potential,” “seeks,” “will” and variations of these words or similar expressions that are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Forward-looking statements in this press release include, but are not limited to, statements regarding: the therapeutic potential, safety, and efficacy of Eikon’s product candidates; the timing for anticipated data readouts; expected milestones and business objectives for 2026 and beyond, including the anticipated cash runway into the first quarter of 2028; and other statements regarding Eikon’s future operations, financial performance, financial position, prospects, objectives, strategies and other future events.

These forward-looking statements are based upon management’s current expectations and assumptions, and are subject to a number of risks, uncertainties and other factors that could cause actual results and events to differ materially and adversely from those indicated by such forward-looking statements including, among others: Eikon’s limited operating history; its significant net losses incurred since inception and the likelihood of incurring additional losses for the foreseeable future; its need for substantial additional funding; the early stage of development of many of its product candidates and the possibility that its product candidates may fail in development; its dependence on the success of its current product candidates; its ability to leverage its technology platform to enable more informed drug research and development; legal and regulatory risks; intellectual property-related risks; and those risks, uncertainties and other factors discussed under the caption “Risk Factors” and elsewhere in Eikon’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2026, filed with the Securities and Exchange Commission (SEC) on November 12, 2026, and in other public filings with the SEC in the future.

As a result, you should not place undue reliance on any forward-looking statements. The forward-looking statements made in this press release speak only as of the date of this press release, and Eikon undertakes no obligation to update such forward-looking statements, whether as a result of new information, future developments or otherwise, except as required by law.

Contacts:

Investors
Alfred “Freddie” Bowie, Ph.D., CFO
ir@eikontx.com

Media
Colin Sanford
colin@bioscribe.com

Eikon Therapeutics, Inc. Statements of Operations and Comprehensive Loss (in thousands, except share and per share amounts) (Unaudited)
	(in thousands, except share and per share amounts)
	Three Months Ended September 30,								Nine Months Ended September 30,
		2026				2025				2026				2025
Operating expenses:
Research and development	$	71,826			$	59,313			$	217,333			$	185,089
General and administrative		18,726				15,438				53,950				70,688
Total operating expenses		90,552				74,751				271,283				255,777
Loss from operations		(90,552	)			(74,751	)			(271,283	)			(255,777	)
Interest income (expense), net		4,486				3,613				13,903				11,207
Other income (expense), net		(46	)			(1	)			(99	)			(23	)
Net loss and comprehensive loss		(86,112	)			(71,139	)			(257,479	)			(244,593	)
Impact of preferred stock extinguishments and modifications		—				—				—				(9,396	)
Net loss attributable to common stockholders	$	(86,112	)		$	(71,139	)		$	(257,479	)		$	(253,989	)
Net loss per share attributable to common stockholders, basic and diluted	$	(1.59	)		$	(24.24	)		$	(5.43	)		$	(89.06	)
Weighted-average shares of common stock outstanding used in computing net loss per share attributable to common stockholders, basic and diluted		54,168,268				2,934,921				47,412,330				2,851,910

Eikon Therapeutics, Inc. Condensed Balance Sheet Data (in thousands) (Unaudited)
	(in thousands)
	September 30, 2026			December 31, 2025
Cash, cash equivalents and marketable securities	$	461,717			$	335,975
Total assets		706,201				594,734
Total liabilities		321,908				312,298
Total stockholders’ equity (deficit)		384,293				(879,034	)

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What were Eikon Therapeutics’ third-quarter 2026 financial results?

Eikon reported a $86.1 million net loss attributable to common stockholders, compared with $71.1 million a year earlier. Research and development expenses rose 21% to $71.8 million, and general and administrative expenses rose 21% to $18.7 million.

What did Eikon’s EIK1001 lung cancer trial show?

In TeLuRide-005, EIK1001 with pembrolizumab and chemotherapy produced a 63.1% objective response rate, meaning measurable tumor shrinkage, and an 89.2% disease control rate among 65 efficacy-evaluable participants. Median follow-up was 17.2 months. The ongoing Phase 2 trial is open-label, meaning treatment assignments are known.

When does Eikon expect its next EIK1001 trial analyses?

Eikon anticipates the TeLuRide-006 melanoma trial’s interim analysis for advancement to Phase 3 in the first half of 2027. It anticipates the TeLuRide-008 lung cancer trial’s interim analysis for dose selection in the second half of 2027. Both are registrational Phase 2/3 trials.