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Enlivex Reports Full-Year 2025 Results: Profit (Net Income) of $1.23 Billion and Diluted Earnings Per Share (EPS) of $25.48

(Moderate)
(Positive)
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Enlivex (Nasdaq: ENLV) reported 2025 audited results with net income $1.23 billion and diluted EPS $25.48, driven by unrealized appreciation in its treasury and treasury-related derivative assets. The company reported $2.31 billion in treasury assets, $1.93 billion shareholders' equity and $30.0 million in cash and short-term digital investments. Enlivex reiterates a dual strategy combining clinical-stage longevity therapeutics and a prediction-markets-backed treasury model and will host a webcast on March 25, 2026 at 09:00 am ET to discuss results.

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Positive

  • Net income $1.23B for full-year 2025
  • Diluted EPS $25.48 reflecting strong per-share profitability
  • Treasury assets $2.31B providing large reported asset base
  • Shareholders' equity $1.93B indicating substantial book value

Negative

  • Profit driven by unrealized treasury appreciation rather than operating cash flow
  • Low $30.0M cash versus $2.31B treasury exposure may limit liquidity flexibility

News Market Reaction – ENLV

+9.09% 6.5x vol
10 alerts
+9.09% Session close to close
+21.7% Peak Tracked
-6.1% Trough Tracked
$284.86M Market Cap
6.5x Rel. Volume

In the Mar 25 session, ENLV gained 9.09%, reflecting a notable positive market reaction. Argus tracked a peak move of +21.7% during that session. Argus tracked a trough of -6.1% from its starting point during tracking. Our momentum scanner triggered 10 alerts that day, indicating notable trading interest and price volatility. Trading volume was exceptionally heavy at 6.5x the daily average, suggesting very strong buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock moved +9.1% in the session following this news. A strong positive reaction aligns with the...
Analysis

The stock moved +9.1% in the session following this news. A strong positive reaction aligns with the report of $1.23 Billion in 2025 net income and diluted EPS of $25.48, largely tied to treasury and derivative asset appreciation of $2.31 Billion. Historically, Enlivex often reacted positively to major strategic or regulatory updates, such as the IND clearance and RAIN exchange listings. Investors would still need to weigh how much of this profit is unrealized and sensitive to digital asset markets, and how prior financing and capital programs might influence future performance.

Key Figures

Net income: $1.23 Billion Diluted EPS: $25.48 Treasury & derivative assets: $2.31 Billion +5 more
8 metrics
Net income $1.23 Billion Full year 2025, driven by treasury and derivative asset appreciation
Diluted EPS $25.48 Full year 2025 diluted earnings per ordinary share
Treasury & derivative assets $2.31 Billion Total treasury and treasury-related derivative assets as of Dec 31, 2025
Shareholders’ equity $1.93 Billion Audited balance sheet as of Dec 31, 2025
Cash & equivalents $30.0 million Cash, cash equivalents, and short-term digital asset investments
ATM capacity $250,000,000 Ordinary shares offered under updated at-the-market Sales Agreement
Initial ATM registration $299,553,108 Initially registered amount under BTIG at-the-market Sales Agreement
ATM gross proceeds $2,513,111 Aggregate gross proceeds from 1,936,660 shares sold via ATM

Historical Context

5 past events · Latest: Mar 24 (Neutral)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 24 Debt & buyback Neutral -0.9% Convertible note financing, RAIN token purchases, and $20M repurchase program.
Mar 23 Clinical IND clearance Positive +8.8% FDA IND clearance for global Phase 2b Allocetra knee osteoarthritis trial.
Feb 10 Crypto listing update Positive +0.0% RAIN token listed on Kraken, expanding access and liquidity for treasury asset.
Jan 26 Crypto listing update Positive +8.3% RAIN token listed on WhiteBIT to broaden regional market access and liquidity.
Jan 23 Listing change Positive +2.9% Voluntary delisting from TASE to focus trading and reporting on Nasdaq.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news has usually led to positive or flat reactions, with only one notable divergence where positive news saw no price move.

Recent Company History

Over recent months, Enlivex has advanced both its clinical and treasury strategies. In January 2026, listings of its primary treasury asset RAIN on WhiteBIT and later Kraken coincided with positive to flat share reactions. A January 23 move to trade exclusively on Nasdaq also saw a modest gain. In March 2026, FDA IND clearance for a Phase 2b Allocetra trial drove an 8.82% rise, while a subsequent $21M debt financing and $20M repurchase program aligned with a small decline. Today’s 2025 profit release fits into this dual-engine narrative.

Key Terms

treasury-related derivative assets, prediction markets infrastructure, macrophage reprogramming therapies, decentralized prediction markets protocol
4 terms
prediction markets infrastructure technical
"prediction markets infrastructure. Full Year 2025 Financial Summary"
Prediction markets infrastructure is the set of software, rules and services that let people trade contracts whose value depends on future events — like a betting exchange where prices reflect the crowd’s view of how likely something is to happen. For investors it matters because those market prices provide fast, tradable signals about expected outcomes and offer tools to hedge or express views, while the infrastructure’s reliability, speed, costs and legal setup shape how useful and risky those signals are.
macrophage reprogramming therapies medical
"including macrophage reprogramming therapies targeting the growing longevity market"
Macrophage reprogramming therapies are treatments that change the behavior of macrophages, a type of immune cell, so they stop causing harmful inflammation or start helping repair tissue. Investors care because these therapies target underlying disease processes rather than just symptoms, which can lead to larger, longer-lasting clinical benefits and potentially high commercial value—think of retraining a malfunctioning repair crew to fix a building properly rather than repeatedly patching it.
decentralized prediction markets protocol technical
"treasury model anchored in the RAIN decentralized prediction markets protocol."
A decentralized prediction markets protocol is a blockchain-based platform that lets anyone create and join markets where people place small stakes on the outcome of real-world events, and payouts are handled automatically without a central operator. Think of it as a public bulletin board where many people vote with money on what will happen next; the aggregated bets can reveal crowd-based forecasts, create new revenue or token value, and carry regulatory and liquidity risks that investors should weigh.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Earnings Driven by Treasury and Treasury-Related Asset Appreciation

Nes-Ziona, Israel, March 25, 2026 (GLOBE NEWSWIRE) -- Enlivex Ltd. (Nasdaq: ENLV; “Enlivex” or “the Company”) today reported financial results and business highlights for the year ended December 31, 2025.

Net income for the year ended December 31, 2025 was $1.23 Billion and diluted earnings per ordinary share (EPS) was $25.48, driven by appreciation in the valuation of the Company’s treasury and treasury-related derivative assets. Enlivex is a quality longevity Company powered by a Prediction Markets Treasury, reflecting the Company’s dual strategy spanning quality longevity therapeutics and prediction markets infrastructure.

Full Year 2025 Financial Summary (audited balance sheet data as of December 31, 2025)

  •     Net income: $1.23 Billion
  •     Diluted earnings per share (EPS): $25.48
  •     Total treasury and treasury-related derivative assets: $2.31 Billion
  •     Shareholders’ equity: $1.93 Billion
  •     Cash, cash equivalents, and short-term investments in digital assets: $30.0 million

Shai Novik, Executive Chairman of Enlivex, stated, "2025 marked a pivotal year for Enlivex as we advanced our vision of becoming a quality longevity company powered by a Prediction Markets Treasury. Our clinical operations continue to progress with Allocetra™ and its potential to restore mobility and independence in aging populations. In parallel, our treasury operations establish exposure to prediction markets infrastructure through the RAIN protocol, creating a capital strategy designed to align long-term shareholder value with the growth of decentralized forecasting markets. Together, these two strategies position Enlivex to pursue innovation in quality longevity therapeutics while developing an innovative treasury model for a public company, which contributed to strong profitability for Enlivex in 2025 based on the unrealized appreciation in the Company’s treasury and treasury-related derivative assets."

Enlivex Dual Strategy
Enlivex’s strategy combines a clinical-stage immunotherapy platform focused on quality longevity therapeutics, including macrophage reprogramming therapies targeting the growing longevity market, with a treasury model anchored in the RAIN decentralized prediction markets protocol. The Company believes this dual structure provides public market investors exposure to emerging prediction markets infrastructure while the Company continues to advance its clinical development programs focused on improving healthspan and quality of life.

Enlivex 2025 Earnings Webcast

A webcast to discuss the Company’s financial results, outlook and related matters will be held at 09:00 am (ET) today. The webcast will be open to the public.

Members of the public who would like to participate in the webcast should register in advance via the following link: https://redchip.zoom.us/webinar/register/WN_WDBHk6K7SgKbhmmKy58Tvw

After registering, participants will receive a confirmation email containing information about joining the webcast. The webcast will also be accessible as an audio webcast through the Investor Relations section of the Company’s website, www.enlivex.com/investors.

About Enlivex Ltd. (Nasdaq: ENLV)

Enlivex is a quality longevity company powered by a prediction markets treasury. The Company is advancing Allocetra™, an advanced clinical-stage immunotherapy targeting inflammatory conditions associated with aging with a primary focus on age-related osteoarthritis.

In addition to its clinical programs, Enlivex operates a prediction markets treasury strategy built around the Rain protocol, the leading decentralized prediction markets infrastructure on Arbitrum. This dual strategy combines the development of quality longevity therapeutics with exposure to the emerging prediction markets ecosystem.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements may be identified by words such as “expects,” “plans,” “projects,” “will,” “may,” “anticipates,” “believes,” “should,” “would,” “could,” “intends,” “estimates,” “suggests,” “target,” “has the potential to,” “goal,” and other words of similar meaning, including statements relating to the anticipated benefits of the Company’s digital asset treasury strategy; the assets to be held by the Company; the expected future market, price, trading activity, and liquidity of the RAIN token; the impact of expanded exchange listings and increased token liquidity on market participation and accessibility; the potential effects of digital asset liquidity on the liquidity of the Company’s ordinary shares; macroeconomic, political, and regulatory conditions surrounding digital assets; the Company’s plans for value creation and strategic positioning; market size and growth opportunities; regulatory conditions; competitive position; technological and market trends; future financial condition and performance; expected clinical trial results; market opportunities for the results of current clinical studies and preclinical experiments; and the effectiveness of, and market opportunities for, ALLOCETRA™ programs. Each forward-looking statement contained in this press release is subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statement. Applicable risks and uncertainties include, among others, the risk of failure to realize the anticipated benefits of the Company’s digital asset treasury strategy; changes in business, market, financial, political, and regulatory conditions; risks relating to the Company’s operations and business, including the highly volatile nature of the price, trading volume, and liquidity of RAIN and other cryptocurrencies; risks associated with digital asset exchange listings, trading venues, and market infrastructure; the risk that the price and liquidity of the Company’s ordinary shares may be correlated with the price or liquidity of the digital assets it holds; risks related to increased competition in the industries in which the Company operates; risks relating to significant legal, commercial, regulatory, and technical uncertainty regarding digital assets generally; risks relating to the treatment of crypto assets for U.S. and foreign tax purposes; and those risks and uncertainties identified in the Company’s filings with the Securities and Exchange Commission. The forward-looking statements in this press release speak only as of the date of this document, and the Company undertakes no obligation to update or revise any of these statements, except as required by applicable law.

ENLIVEX CONTACT

Shachar Shlosberger, CFO
Enlivex Ltd.
shachar@enlivex.com

 


FAQ

What were Enlivex (ENLV) full-year 2025 net income and EPS?

Net income was $1.23 billion and diluted EPS was $25.48. According to the company, these results were driven primarily by unrealized appreciation in treasury and treasury-related derivative assets rather than operating earnings.

How large were Enlivex's treasury and shareholders' equity at year-end 2025 (ENLV)?

Enlivex reported $2.31 billion in treasury and treasury-related derivative assets and $1.93 billion shareholders' equity. According to the company, the treasury valuation gains materially contributed to 2025 profitability.

How much cash did Enlivex (ENLV) hold at December 31, 2025 and does it affect liquidity?

Enlivex reported $30.0 million in cash, cash equivalents, and short-term digital investments at year-end. According to the company, cash balances are small relative to its treasury exposure, which investors may view as a liquidity consideration.

Why did Enlivex (ENLV) report large 2025 profits despite clinical-stage operations?

The company attributes 2025 profitability to unrealized appreciation in treasury and derivative assets rather than product revenue. According to the company, its dual strategy pairs clinical programs with a prediction-markets-backed treasury model that drove valuation gains.

When and how can investors listen to Enlivex's 2025 earnings webcast (ENLV)?

The webcast was scheduled for March 25, 2026 at 09:00 am ET and was open to the public with advance registration. According to the company, an audio webcast is also available via its investor relations website.