Welcome to our dedicated page for Erasca news (Ticker: ERAS), a resource for investors and traders seeking the latest updates and insights on Erasca stock.
Erasca, Inc. (ERAS) is a clinical-stage precision oncology company pioneering therapies for cancers driven by RAS/MAPK pathway abnormalities. This page serves as the definitive source for official updates spanning clinical developments, regulatory milestones, and strategic initiatives.
Investors and researchers will find curated news about Erasca’s pipeline candidates including pan-RAF inhibitor naporafenib, ERK1/2 inhibitor ERAS-007, and emerging preclinical assets. Our repository includes trial progress reports, partnership announcements, and scientific presentations – all essential for tracking advancements in targeted cancer therapies.
Regular updates cover key areas: clinical trial phase transitions, FDA designations, collaborative research agreements, and preclinical discoveries. Each release is vetted for accuracy, providing reliable insights into Erasca’s mission to disrupt oncogenic signaling pathways.
Bookmark this page for streamlined access to ERAS news. Combine our updates with SEC filings and scientific publications for comprehensive analysis of this innovative oncology biotech.
Erasca, a clinical-stage oncology company, announced significant developments in its recent press release. The company signed an exclusive worldwide license for naporafenib, a pan-RAF inhibitor, and completed a $100 million equity offering. It plans multiple clinical data readouts throughout 2023, including for its ERAS-007 and ERAS-601 therapies. As of December 31, 2022, Erasca had a robust balance sheet with cash and equivalents totaling $436 million, expected to support operations into H2 2025. However, the company reported a net loss of $242.8 million for the full year 2022, primarily due to in-process R&D expenses associated with the naporafenib licensing agreement.
Erasca Inc. (Nasdaq: ERAS) announced a poster presentation at the AACR Annual Meeting on April 18, 2023, discussing preliminary Phase 1 dose escalation data for ERAS-601, a potential best-in-class SHP2 inhibitor, in combination with cetuximab. This study focuses on advanced or metastatic solid tumors. The poster will be available online post-presentation. The company emphasized its mission to develop therapies targeting RAS/MAPK pathway-driven cancers and highlighted the scientific expertise behind its cancer treatments. Caution is advised regarding forward-looking statements on product efficacy and potential risks in clinical development.
On February 1, 2023, Erasca, Inc. (Nasdaq: ERAS) announced its participation in the Guggenheim Oncology Conference 2023. The event will feature a fireside chat with CEO Jonathan E. Lim, M.D., and CFO David M. Chacko at 1:00 PM ET on February 8, 2023. They will also engage in one-on-one investor meetings. A live webcast will be available, with an archived replay accessible for 30 days post-event. Erasca focuses on developing therapies for patients with RAS/MAPK pathway-driven cancers, aiming to be a leader in precision oncology.
Erasca, Inc. (Nasdaq: ERAS), a clinical-stage precision oncology company, will participate in the 41st annual J.P. Morgan Healthcare Conference on January 9, 2023, at 8:15 am PT. CEO Dr. Jonathan E. Lim will present an overview of the company and its RAS/MAPK pathway-focused pipeline in Elizabethan Room C of the Westin St. Francis Hotel, San Francisco. Additionally, Dr. Lim and CFO David M. Chacko will engage in one-on-one investor meetings. A live audio webcast of the event will be available on Erasca's website, with an archived replay accessible for 30 days.
Erasca, Inc. (Nasdaq: ERAS) announced the dosing of the first patient in the HERKULES-1 Phase 1b trial, evaluating the ERK1/2 inhibitor ERAS-007 and SHP2 inhibitor ERAS-601 in advanced solid tumors. The trial aims to assess safety and efficacy in RAS/MAPK pathway-altered tumors. Preliminary data showed positive responses; 44% of patients with BRAF-driven tumors exhibited responses to either monotherapy ERAS-007 or ERAS-601. This highlights the potential of targeting BRAF Class 2 and 3 alterations, which currently lack approved therapies, representing a significant unmet need in oncology.
Erasca, Inc. (Nasdaq: ERAS) announced FDA clearance of an IND application for ERAS-3490, a small molecule KRAS G12C inhibitor aimed at treating solid tumors with high CNS penetration. The drug targets the KRAS G12C mutation, prevalent in various cancers, including non-small cell lung cancer (NSCLC), where CNS metastases affect up to 40% of patients. Nonclinical data show strong anti-tumor activity and survival benefits in relevant cancer models, underscoring the potential of ERAS-3490 in precision oncology.
Erasca, Inc. (Nasdaq: ERAS) has entered a $100 million equity offering to support its exclusive worldwide license agreement with Novartis for naporafenib, a promising cancer treatment targeting NRAS mutant melanoma and other RAS/MAPK-driven tumors. Naporafenib has been evaluated in over 500 patients, showing strong safety and efficacy as both a single agent and in combination therapies. The agreement includes a $20 million upfront cash payment and stock issuance, and could yield up to $280 million in milestone payments for Novartis. A conference call will elaborate on these developments.
Erasca, Inc. (Nasdaq: ERAS) announced a pricing of an underwritten offering of 15,384,616 shares of common stock at $6.50 each, aiming to raise approximately $100 million. All shares are offered by Erasca, expected to close on December 13, 2022, pending customary closing conditions. Proceeds will support research and development of product candidates, working capital, and general corporate purposes. The offering is filed under a previously effective shelf registration with the SEC.
ERAS-007, a promising ERK1/2 inhibitor, is undergoing evaluation in combination with encorafenib and cetuximab for BRAF V600E-mutant metastatic colorectal cancer (mCRC). Erasca has formed a clinical trial collaboration with Pierre Fabre to facilitate this study, broadening its reach in Europe and Asia Pacific. Encorafenib, previously approved for mCRC, shows limited efficacy, with only 20% of patients responding. The aim of this combination therapy is to enhance treatment outcomes by reducing resistance mechanisms. This partnership complements existing collaborations with Pfizer.
Erasca, Inc. (Nasdaq: ERAS), a clinical-stage precision oncology company, has announced presentations at two upcoming investor conferences. The 5th Annual Evercore ISI HealthCONx Conference will be held virtually from November 29 to December 1, with a fireside chat scheduled for November 29 at 8:50 AM EST. Additionally, the Bank of America SMID Cap Conference is set for December 7-8, featuring a fireside chat on December 8 at 11:25 AM EST. Archived replays of both events will be available until February 2023. Visit Erasca.com/events for more details.
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