Welcome to our dedicated page for Esperion Therape news (Ticker: ESPR), a resource for investors and traders seeking the latest updates and insights on Esperion Therape stock.
Esperion Therapeutics, Inc. (NASDAQ: ESPR) is a commercial-stage biopharmaceutical company focused on cardiometabolic and rare/orphan disease therapies, with an emphasis on oral, once-daily, non-statin treatments for patients with elevated LDL-C who are at risk for cardiovascular disease. This news page aggregates company announcements, clinical updates, partnership developments, and financial disclosures related to Esperion and its products.
Investors and healthcare-focused readers can use this feed to follow Esperion’s progress with NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe), including regulatory milestones, commercialization updates, and guideline-related developments. Recent company communications highlight inclusion of bempedoic acid in major cardiovascular guidelines, presentations of new analyses from the CLEAR Outcomes trial, and expansion of access through partners in Europe, Japan, Canada and other regions.
News items also cover Esperion’s pipeline activities, such as the nomination of ESP-2001, a highly specific allosteric ATP-citrate lyase inhibitor for primary sclerosing cholangitis, and broader ACLY-focused research efforts. Financial and corporate updates, including quarterly results, capital raises via public offerings, and executive appointments, are reported through press releases and Form 8-K filings and are reflected in this news stream.
By reviewing the ESPR news feed, readers can see how Esperion describes its Vision 2040 strategy, commercial execution in the U.S. statin-intolerant market, international launches with partners, and ongoing safety and indication communications for NEXLETOL and NEXLIZET. This page offers a centralized view of the company’s publicly released information over time.
Esperion (NASDAQ:ESPR) announced record-breaking financial results for Q2 2020, achieving total revenue of $212.2 million and $214.1 million for the first half of the year. Strong commercial traction was highlighted by over 80% commercial and 50% Medicare Part D formulary coverage for its products NEXLETOL® and NEXLIZET™. The company ended the second quarter with a robust cash position of over $300 million. Esperion also reported a net income of $124.6 million for the quarter, compared to a net loss in the same quarter the previous year.
Esperion (NASDAQ: ESPR) will report its second quarter 2020 financial results on August 10, 2020. Following the release, a conference call will be held at 4:30 p.m. ET to discuss the results and business progress. Esperion is focused on developing oral medications to lower LDL-C, addressing the significant health challenge posed by high cholesterol levels. Approximately 96 million adult Americans suffer from high LDL-C, with many unable to reach target levels using current therapies. The company aims to significantly impact cardiovascular health through its innovations.
Esperion (NASDAQ: ESPR) announced a publication in JAMA Cardiology detailing a pooled efficacy analysis from four Phase 3 studies of NEXLETOL, an oral LDL-cholesterol lowering medication. The studies involved 3,623 patients and demonstrated that NEXLETOL, when added to statin therapy, significantly lowered LDL-C by 18% versus placebo, and by 24% in statin-intolerant patients. The drug is intended for those with familial hypercholesterolemia or established cardiovascular disease needing additional LDL-C reduction. The safety profile showed similar adverse event rates between NEXLETOL and placebo.
Esperion (NASDAQ: ESPR) announced a $150 million milestone payment from Daiichi Sankyo Europe (DSE), which will be received this month due to the transfer of Marketing Authorization Approvals (MAAs) for NILEMDO and NUSTENDI. This agreement allows DSE to commercialize the drugs in Europe. With this payment, Esperion will have received $300 million in total milestone payments. Additionally, Esperion is conducting the CLEAR Cardiovascular Outcomes Trial to assess the impact of bempedoic acid on cardiovascular health for patients unable to tolerate statins.
Esperion (NASDAQ: ESPR) presented a pooled analysis from four Phase 3 clinical studies of NEXLETOL at the American Diabetes Association's 80th Scientific Sessions. The study revealed significant reductions in LDL cholesterol and other cholesterol markers among patients with diabetes, prediabetes, and normoglycemia. NEXLETOL also lowered hemoglobin A1c by 0.19%. The safety profile was consistent across all glycemic status subgroups. This analysis supports the efficacy and safety of NEXLETOL, which is a first-in-class oral medication approved for LDL-C lowering.
Esperion (NASDAQ: ESPR) received notice that the Institute for Clinical and Economic Review (ICER) will assess non-statin medicines for hypercholesterolemia, including the cost-effectiveness of NEXLETOL, with a report expected by February 2021. The company has achieved over 70% commercial and 40% Medicare Part D formulary coverage for NEXLETOL, aiming for affordable access to its treatment. Esperion is committed to patient access and has initiated the CLEAR Cardiovascular Outcomes Trial to evaluate NEXLETOL’s effects on cardiovascular events in statin-averse patients.
Esperion (NASDAQ: ESPR) announced that its CEO, Tim M. Mayleben, will participate in an analyst-led fireside chat at the Goldman Sachs 41st Annual Global Healthcare Conference on June 11, 2020, at 4:40 p.m. ET. The event will be available via a live audio webcast on Esperion's investor relations website, with a replay accessible for 90 days afterward. Esperion is dedicated to developing oral medicines focused on lowering LDL-C to combat cardiovascular diseases, which affect millions in the U.S. Due to the high prevalence of elevated LDL-C levels, the company aims to offer effective solutions to improve patient outcomes.
Esperion (NASDAQ: ESPR) announced the launch of NEXLIZETTM (bempedoic acid and ezetimibe), the first approved non-statin LDL-C lowering combination medicine, now available in U.S. pharmacies. The drug achieves a mean LDL-C reduction of 38% when added to statins, with minimal paperwork for healthcare providers. NEXLIZET aims to set a new standard for affordability with broad payer coverage and a low co-pay for eligible patients. The launch has been accelerated by one month in response to healthcare provider requests, emphasizing the urgent need for additional cholesterol-lowering options.
Esperion (NASDAQ: ESPR) announced the grant of 88,902 restricted stock units (RSUs) to 194 new employees as part of its 2017 Inducement Equity Incentive Plan. The RSUs will vest over four years, with 25% after one year and the remaining 75% quarterly. This grant aims to attract talent as the company continues its mission of developing LDL-C lowering medicines to address cardiovascular disease. The press release contains forward-looking statements regarding clinical development and commercialization plans that carry inherent risks and uncertainties.
Esperion (NASDAQ: ESPR) announced that CEO Tim M. Mayleben will engage in an analyst-led fireside chat at the BofA Securities 2020 Healthcare Conference on May 12, 2020, at 9:00 a.m. ET. Interested parties can access a live audio webcast from the investor relations section of Esperion's website. The discussion will emphasize the company's efforts in cholesterol management, specifically targeting LDL-C levels. Esperion's mission is to develop oral medications that can significantly reduce LDL-C, combating the prevalence of cardiovascular diseases.