Amicus Therapeutics Announces Second Quarter 2025 Financial Results and Corporate Updates
Amicus Therapeutics (Nasdaq: FOLD) reported strong Q2 2025 financial results with total revenue of $154.7M, up 18% at constant exchange rates. The company's performance was driven by two commercial therapies: Galafold revenue reached $128.9M (up 12%) and Pombiliti + Opfolda achieved $25.8M (up 58%).
Key highlights include Japanese regulatory approval for Pombiliti + Opfolda in adult LOPD patients, progress in the ACTION3 Study of DMX-200 for FSGS, and anticipated GAAP profitability in H2 2025. The company maintains its 2025 guidance with projected revenue growth of 15-22% and expects to exceed $1 billion in total revenue by 2028.
Q2 GAAP net loss was $24.4M ($0.08 per share), while non-GAAP net income was $1.9M ($0.01 per share). Cash position stood at $231.0M as of June 30, 2025.
Amicus Therapeutics (Nasdaq: FOLD) ha riportato solidi risultati finanziari per il secondo trimestre 2025 con un fatturato totale di 154,7 milioni di dollari, in crescita del 18% a tassi di cambio costanti. La performance dell'azienda è stata trainata da due terapie commerciali: il ricavo di Galafold ha raggiunto 128,9 milioni di dollari (in aumento del 12%) e Pombiliti + Opfolda ha totalizzato 25,8 milioni di dollari (in crescita del 58%).
Tra i principali eventi si segnalano l'approvazione regolatoria in Giappone per Pombiliti + Opfolda nei pazienti adulti con LOPD, i progressi nello studio ACTION3 di DMX-200 per FSGS e la previsione di redditività GAAP nella seconda metà del 2025. L'azienda conferma le previsioni per il 2025 con una crescita del fatturato stimata tra il 15% e il 22% e si aspetta di superare 1 miliardo di dollari di fatturato totale entro il 2028.
La perdita netta GAAP del secondo trimestre è stata di 24,4 milioni di dollari (0,08 dollari per azione), mentre l'utile netto non GAAP è stato di 1,9 milioni di dollari (0,01 dollari per azione). La posizione di cassa al 30 giugno 2025 era di 231,0 milioni di dollari.
Amicus Therapeutics (Nasdaq: FOLD) reportó sólidos resultados financieros en el segundo trimestre de 2025 con ingresos totales de $154.7M, un aumento del 18% a tipos de cambio constantes. El desempeño de la empresa estuvo impulsado por dos terapias comerciales: los ingresos de Galafold alcanzaron $128.9M (un aumento del 12%) y Pombiliti + Opfolda lograron $25.8M (un incremento del 58%).
Los aspectos destacados incluyen la aprobación regulatoria en Japón para Pombiliti + Opfolda en pacientes adultos con LOPD, avances en el estudio ACTION3 de DMX-200 para FSGS y la rentabilidad GAAP anticipada para la segunda mitad de 2025. La compañía mantiene su guía para 2025 con un crecimiento proyectado de ingresos del 15-22% y espera superar los $1 mil millones en ingresos totales para 2028.
La pérdida neta GAAP en el segundo trimestre fue de $24.4M ($0.08 por acción), mientras que el ingreso neto no GAAP fue de $1.9M ($0.01 por acción). La posición de efectivo al 30 de junio de 2025 fue de $231.0M.
아미커스 테라퓨틱스 (Nasdaq: FOLD)는 2025년 2분기에 총 매출 1억 5470만 달러를 기록하며 환율 변동을 고려한 기준으로 18% 성장한 강력한 실적을 발표했습니다. 회사의 성과는 두 가지 상업용 치료제에 의해 견인되었으며, Galafold 매출은 1억 2890만 달러(12% 증가), Pombiliti + Opfolda는 2580만 달러(58% 증가)를 기록했습니다.
주요 하이라이트로는 일본에서 성인 LOPD 환자를 위한 Pombiliti + Opfolda의 규제 승인, FSGS 치료제 DMX-200의 ACTION3 연구 진전, 2025년 하반기 GAAP 수익성 예상이 포함됩니다. 회사는 2025년 매출 성장률 15-22% 전망을 유지하며, 2028년까지 총 매출 10억 달러 이상 달성을 기대하고 있습니다.
2분기 GAAP 순손실은 2440만 달러(주당 0.08달러)였으며, 비GAAP 순이익은 190만 달러(주당 0.01달러)였습니다. 2025년 6월 30일 기준 현금 보유액은 2억 3100만 달러였습니다.
Amicus Therapeutics (Nasdaq : FOLD) a annoncé de solides résultats financiers pour le deuxième trimestre 2025 avec un chiffre d'affaires total de 154,7 millions de dollars, en hausse de 18 % à taux de change constants. La performance de l'entreprise a été portée par deux thérapies commerciales : le chiffre d'affaires de Galafold a atteint 128,9 millions de dollars (en hausse de 12 %) et Pombiliti + Opfolda a réalisé 25,8 millions de dollars (en progression de 58 %).
Les points clés incluent l'approbation réglementaire japonaise pour Pombiliti + Opfolda chez les patients adultes atteints de LOPD, les progrès de l'étude ACTION3 sur le DMX-200 pour la FSGS, et la rentabilité GAAP attendue au second semestre 2025. L'entreprise maintient ses prévisions pour 2025 avec une croissance du chiffre d'affaires projetée entre 15 et 22 % et prévoit de dépasser 1 milliard de dollars de chiffre d'affaires total d'ici 2028.
La perte nette GAAP du deuxième trimestre s'est élevée à 24,4 millions de dollars (0,08 dollar par action), tandis que le bénéfice net non GAAP était de 1,9 million de dollars (0,01 dollar par action). La trésorerie au 30 juin 2025 s'élevait à 231,0 millions de dollars.
Amicus Therapeutics (Nasdaq: FOLD) meldete starke Finanzergebnisse für das zweite Quartal 2025 mit einem Gesamtumsatz von 154,7 Mio. USD, was einem Anstieg von 18 % bei konstanten Wechselkursen entspricht. Die Leistung des Unternehmens wurde von zwei kommerziellen Therapien getragen: Der Umsatz von Galafold erreichte 128,9 Mio. USD (plus 12 %) und Pombiliti + Opfolda erzielten 25,8 Mio. USD (plus 58 %).
Zu den wichtigsten Highlights zählen die Zulassung von Pombiliti + Opfolda in Japan für erwachsene LOPD-Patienten, Fortschritte in der ACTION3-Studie zu DMX-200 bei FSGS sowie die erwartete GAAP-Rentabilität in der zweiten Hälfte des Jahres 2025. Das Unternehmen bestätigt seine Prognose für 2025 mit einem erwarteten Umsatzwachstum von 15-22 % und rechnet damit, bis 2028 einen Gesamtumsatz von über 1 Milliarde USD zu erzielen.
Der GAAP-Nettogewinn im zweiten Quartal betrug -24,4 Mio. USD (-0,08 USD je Aktie), während der Non-GAAP-Nettogewinn 1,9 Mio. USD (0,01 USD je Aktie) betrug. Die Barbestände beliefen sich zum 30. Juni 2025 auf 231,0 Mio. USD.
- Total revenue growth of 18% at CER, marking 17th consecutive quarter of double-digit gains
- Galafold revenue up 12% to $128.9M driven by new patient starts and strong compliance
- Pombiliti + Opfolda revenue surged 58% to $25.8M with launches in five countries
- Japanese regulatory approval obtained for Pombiliti + Opfolda
- Company expects to achieve GAAP profitability in H2 2025
- Projected to exceed $1B in total revenue by 2028
- GAAP net loss increased to $24.4M from $15.7M year-over-year
- Operating expenses increased 48% to $148.9M, including $30M upfront payment for DMX-200 licensing
- Cash position decreased to $231.0M from $249.9M at end of 2024
Insights
Amicus delivers strong 18% growth with both products performing well, maintains guidance including H2 2025 profitability milestone.
Amicus Therapeutics delivered a solid Q2 2025 with
Breaking down the revenue components, Galafold generated
The company reported a GAAP net loss of
The cash position remains solid at
The pipeline is advancing with the ACTION3 study of DMX-200 on track to complete enrollment by year-end, potentially adding a third commercial asset in the medium term. Additionally, Pombiliti+Opfolda received regulatory approval in Japan in June, with up to 10 new launch countries expected in 2025, which should drive further growth.
Looking further ahead, management has set an ambitious goal of exceeding
Q2 2025 Total Revenue of
Galafold® Q2 Revenue of
Pombiliti® + Opfolda® Q2 Revenue of
Reiterating 2025 Financial Guidance including GAAP Profitability During H2 2025
Conference Call and Webcast Today at 8:30 a.m. ET
PRINCETON, N.J., July 31, 2025 (GLOBE NEWSWIRE) -- Amicus Therapeutics (Nasdaq: FOLD), a patient-dedicated global biotechnology company focused on developing and commercializing novel medicines for rare diseases, today announced financial results for the quarter ended June 30, 2025.
"We delivered strong second quarter growth of
Second Quarter 2025 Financial Highlights:
- Total revenues for the second quarter 2025 were
$154.7 million , reflecting strong operational growth measured at constant exchange rates (CER)1 of18% and a currency tailwind of$5 million or4% .
(in thousands) | Three Months Ended June 30, | Year over Year % Growth | Six Months Ended June 30, | Year over Year % Growth | |||||||||||||||||||
2025 | 2024 | Reported | at CER1 | 2025 | 2024 | Reported | at CER1 | ||||||||||||||||
Galafold® | $ | 128,872 | $ | 110,817 | $ | 233,116 | $ | 210,176 | |||||||||||||||
Pombiliti® + Opfolda® | $ | 25,816 | $ | 15,852 | $ | 46,821 | $ | 26,896 | |||||||||||||||
Net Product Revenues | $ | 154,688 | $ | 126,669 | $ | 279,937 | $ | 237,072 | |||||||||||||||
- Galafold (migalastat) net product sales for the second quarter 2025 were
$128.9 million , representing a year-over-year increase of16% , or12% at CER1, driven by continued commercial execution in all markets, net new patient starts, and strong compliance. - Pombiliti (cipaglucosidase alfa-atga) + Opfolda (miglustat) net product sales for the second quarter 2025 were
$25.8 million , representing a year-over-year increase of63% , or58% at CER1, driven by high commercial demand and new launches in five countries. - Total GAAP operating expenses, which include the upfront payment of
$30 million for the U.S. licensing agreement of DMX-200, of$148.9 million for the second quarter 2025 increased by48% as compared to$100.4 million for the second quarter 2024. Total non-GAAP operating expenses2, which also include the upfront payment of$30 million for the U.S. licensing agreement of DMX-200, were up56% to$127.8 million for the second quarter 2025 as compared to$82.1 million for the second quarter 2024. - GAAP net loss was
$24.4 million , or$0.08 loss per share basic and diluted, for the second quarter 2025, compared to a net loss of$15.7 million , or$0.05 per share basic and diluted, for the second quarter 2024. Non-GAAP net income2,3 was$1.9 million , or$0.01 per share basic and diluted, for the second quarter 2025, compared to non-GAAP net income of$18.5 million , or$0.06 per share basic and diluted, for the second quarter 2024. - Cash, cash equivalents, and marketable securities totaled
$231.0 million at June 30, 2025 as compared to$249.9 million at December 31, 2024. Current cash position reflects the$30 million upfront payment in the second quarter for the U.S. licensing agreement of DMX-200.
Corporate Updates:
- Pombiliti + Opfolda regulatory approval granted in Japan for adult LOPD patients in June. The Company also continues to anticipate additional reimbursement agreements throughout the year and remains on track for up to 10 new launch countries in 2025.
- New analysis of data from the ERT-experienced cohort of the PROPEL study of cipaglucosidase alfa + miglustat published in Muscle and Nerve. As previously announced, in this new publication, based on a within group effect-size analysis, subjects who switched from alglucosidase alfa to cipaglucosidase alfa + miglustat achieved improvements or stability in most of the outcomes measured.
- ACTION3 Study of DMX-200 is on track for full enrollment by end of year. As announced in May, Amicus entered into a licensing agreement with Dimerix for exclusive rights for the U.S. commercialization of their Phase 3 asset, DMX-200. DMX-200 is a first in class treatment for FSGS, a rare and fatal kidney disease with no approved therapies and significant market potential. The ACTION3 study, being funded and executed by Dimerix, is on track for full enrollment by end of the year.
2025 Financial Guidance
Amicus reiterates its financial guidance for 2025, as follows:
Total Revenue Growth1 | ||
Galafold Revenue Growth1 | ||
Pombiliti + Opfolda Revenue Growth1 | ||
Gross Margin | Mid | |
Non-GAAP Operating Expenses4 | (Incl. | |
GAAP Net Income | Positive during H2 2025 | |
1 In order to illustrate underlying performance, Amicus discusses its results in terms of constant exchange rate (CER) growth. This represents growth calculated as if the exchange rates had remained unchanged from those used in the comparative period.
2 Full reconciliation of GAAP results to the Company’s non-GAAP adjusted measures for all reporting periods appear in the tables to this press release.
3 Amicus defines non-GAAP Net (Loss) Income as GAAP Net (Loss) Income excluding the impact of share-based compensation expense, changes in fair value of contingent consideration, loss on impairment of assets, depreciation and amortization, acquisition related income (expense), loss on extinguishment of debt, restructuring charges and income taxes.
4 A reconciliation of the differences between the non-GAAP expectation and the corresponding GAAP measure is not available without unreasonable effort due to high variability, complexity, and low visibility as to the items that would be excluded from the GAAP measure.
Conference Call and Webcast
Amicus Therapeutics will host a conference call and audio webcast today, July 31, 2025, at 8:30 a.m. ET to discuss the second quarter 2025 financial results and corporate updates. Participants and investors interested in accessing the call by phone will need to register using the online registration form. After registering, all phone participants will receive a dial-in number along with a personal PIN to access the event.
A live audio webcast and related presentation materials can also be accessed via the Investors section of the Amicus Therapeutics corporate website at ir.amicusrx.com. Web participants are encouraged to register on the website 15 minutes prior to the start of the call. An archived webcast and accompanying slides will be available on the Company's website shortly after the conclusion of the live event.
About Galafold
Galafold® (migalastat) 123 mg capsules is an oral pharmacological chaperone of alpha-Galactosidase A (alpha-Gal A) for the treatment of Fabry disease in adults who have amenable galactosidase alpha gene (GLA) variants. In these patients, Galafold works by stabilizing the body’s own dysfunctional enzyme so that it can clear the accumulation of disease substrate. Globally, Amicus Therapeutics estimates that approximately 35 to 50 percent of people living with Fabry disease may have amenable GLA variants, though amenability rates within this range vary by geography. Galafold is approved in more than 40 countries around the world, including the U.S., EU, U.K., and Japan.
U.S. INDICATIONS AND USAGE
Galafold is indicated for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene (GLA) variant based on in vitro assay data.
This indication is approved under accelerated approval based on reduction in kidney interstitial capillary cell globotriaosylceramide (KIC GL-3) substrate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
U.S. IMPORTANT SAFETY INFORMATION
ADVERSE REACTIONS: The most common adverse reactions reported with Galafold (≥
About Pombiliti + Opfolda
Pombiliti + Opfolda, is a two-component therapy that consists of cipaglucosidase alfa-atga, a bis-M6P-enriched rhGAA that facilitates high-affinity uptake through the M6P receptor while retaining its capacity for processing into the most active form of the enzyme, and the oral enzyme stabilizer, miglustat, that’s designed to reduce loss of enzyme activity in the blood.
U.S. INDICATIONS AND USAGE
POMBILITI in combination with OPFOLDA is indicated for the treatment of adult patients with late-onset Pompe disease (lysosomal acid alpha-glucosidase [GAA] deficiency) weighing ≥40 kg and who are not improving on their current enzyme replacement therapy (ERT).
SAFETY INFORMATION
HYPERSENSITIVITY REACTIONS INCLUDING ANAPHYLAXIS: Appropriate medical support measures, including cardiopulmonary resuscitation equipment, should be readily available. If a severe hypersensitivity reaction occurs, POMBILITI should be discontinued immediately and appropriate medical treatment should be initiated. INFUSION-ASSOCIATED REACTIONS (IARs): If severe IARs occur, immediately discontinue POMBILITI and initiate appropriate medical treatment. RISK OF ACUTE CARDIORESPIRATORY FAILURE IN SUSCEPTIBLE PATIENTS: Patients susceptible to fluid volume overload, or those with acute underlying respiratory illness or compromised cardiac or respiratory function, may be at risk of serious exacerbation of their cardiac or respiratory status during POMBILITI infusion. See PI for complete Boxed Warning. CONTRAINDICATION: POMBILITI in combination with Opfolda is contraindicated in pregnancy. EMBRYO-FETAL TOXICITY: May cause embryo-fetal harm. Advise females of reproductive potential of the potential risk to a fetus and to use effective contraception during treatment and for at least 60 days after the last dose. Adverse Reactions: Most common adverse reactions ≥
About Amicus Therapeutics
Amicus Therapeutics (Nasdaq: FOLD) is a global, patient-dedicated biotechnology company focused on discovering, developing and delivering novel high-quality medicines for people living with rare diseases. With extraordinary patient focus, Amicus Therapeutics is committed to advancing and expanding a pipeline of cutting-edge, first- or best-in-class medicines for rare diseases. For more information please visit the company’s website at www.amicusrx.com, and follow on X and LinkedIn.
Non-GAAP Financial Measures
In addition to financial information prepared in accordance with U.S. GAAP, this press release also contains adjusted financial measures that we believe provide investors and management with supplemental information relating to operating performance and trends that facilitate comparisons between periods and with respect to projected information. These adjusted financial measures are non-GAAP measures and should be considered in addition to, but not as a substitute for, the information prepared in accordance with U.S. GAAP. We use these non-GAAP measures as key performance measures for the purpose of evaluating operational performance and cash requirements internally. We typically exclude certain GAAP items that management does not believe affect our basic operations and that do not meet the GAAP definition of unusual or non-recurring items. Other companies may define these measures in different ways. When we provide our expectation for non-GAAP operating expenses and profitability on a forward-looking basis, a reconciliation of the differences between the non-GAAP expectation and the corresponding GAAP measure generally is not available without unreasonable effort due to potentially high variability, complexity and low visibility as to the items that would be excluded from the GAAP measure in the relevant future period, such as unusual gains or losses. The variability of the excluded items may have a significant, and potentially unpredictable, impact on our future GAAP results.
Forward Looking Statement
This press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 relating to the prospects and timing of the potential regulatory and pricing approval of our products, commercialization plans, manufacturing and supply plans, financing plans, the collaboration with Dimerix, and the projected revenues and cash position for the Company. The inclusion of forward-looking statements should not be regarded as a representation by us that any of our plans will be achieved. Any or all of the forward-looking statements in this press release may turn out to be wrong and can be affected by inaccurate assumptions we might make or by known or unknown risks and uncertainties. For example, statements regarding the goals, progress, timing, and outcomes of discussions with regulatory authorities and pricing and reimbursement authorities, are based on current information. Actual results may differ materially from those set forth in this release due to the risks and uncertainties inherent in our business, including, without limitation: the potential that regulatory authorities may not grant or may delay approval for our product candidates; the potential that required regulatory inspections may be delayed or not be successful and delay or prevent product approval; the potential that we may not be successful in negotiations with pricing and reimbursement authorities; the potential that we may not be successful in commercializing Galafold and/or Pombiliti and Opfolda in Europe, the UK, the US and other geographies; the potential that the Dimerix license agreement for of DMX-200 may not be successful, including without limitation expectations of the timing of Phase 3 clinical trial evaluating DMX-200; the likelihood of success of such clinical trial; the prospects for FDA approval of DMX-200 for FSGS or other indications; the estimated prevalence of FSGS; the achievement of any milestone and timing of any payments associated with milestones and the success of any efforts to commercialize DMX-200, including any projections of future financial performance or payments; the potential that we may not be able to manufacture or supply sufficient commercial products; and the potential that we will need additional funding to complete the manufacturing and commercialization of our products. With respect to statements regarding corporate financial guidance and financial goals and the expected attainment of such goals and projections of the Company's revenue, non-GAAP profitability and cash position, actual results may differ based on market factors and the Company's ability to execute its operational and budget plans. In addition, all forward-looking statements are subject to other risks detailed in our Annual Report on Form 10-K for the year ended December 31, 2024 and our Quarterly Report on Form 10-Q to be filed today. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, and we undertake no obligation to revise or update this news release to reflect events or circumstances after the date hereof.
CONTACT:
Investors:
Amicus Therapeutics
Andrew Faughnan
Vice President, Investor Relations
afaughnan@amicusrx.com
(609) 662-3809
Media:
Amicus Therapeutics
Diana Moore
Head of Global Corporate Affairs and Communications
dmoore@amicusrx.com
(609) 662-5079
FOLD-G
TABLE 1
Amicus Therapeutics, Inc. Consolidated Statements of Operations (Unaudited) (in thousands, except share and per share amounts) | |||||||||||||||
Three Months Ended June 30, | Six Months Ended June 30, | ||||||||||||||
2025 | 2024 | 2025 | 2024 | ||||||||||||
Net product sales | $ | 154,688 | $ | 126,669 | $ | 279,937 | $ | 237,072 | |||||||
Cost of goods sold | 15,217 | 11,261 | 26,915 | 24,828 | |||||||||||
Gross profit | 139,471 | 115,408 | 253,022 | 212,244 | |||||||||||
Operating expenses: | |||||||||||||||
Research and development | 60,848 | 24,683 | 88,687 | 53,012 | |||||||||||
Selling, general, and administrative | 84,543 | 73,576 | 176,370 | 161,605 | |||||||||||
Restructuring charges | — | — | — | 6,045 | |||||||||||
Loss on impairment of assets | 1,702 | — | 1,702 | — | |||||||||||
Depreciation and amortization | 1,852 | 2,182 | 3,689 | 4,336 | |||||||||||
Total operating expenses | 148,945 | 100,441 | 270,448 | 224,998 | |||||||||||
Loss from operations | (9,474 | ) | 14,967 | (17,426 | ) | (12,754 | ) | ||||||||
Other expense: | |||||||||||||||
Interest income | 843 | 1,370 | 1,655 | 2,910 | |||||||||||
Interest expense | (11,565 | ) | (12,512 | ) | (23,020 | ) | (24,948 | ) | |||||||
Other income (expense) | 1,015 | (3,717 | ) | 1,565 | (8,683 | ) | |||||||||
Loss before income tax | (19,181 | ) | 108 | (37,226 | ) | (43,475 | ) | ||||||||
Income tax expense | (5,239 | ) | (15,805 | ) | (8,880 | ) | (20,641 | ) | |||||||
Net loss attributable to common stockholders | $ | (24,420 | ) | $ | (15,697 | ) | $ | (46,106 | ) | $ | (64,116 | ) | |||
Net loss attributable to common stockholders per common share — basic and diluted | $ | (0.08 | ) | $ | (0.05 | ) | $ | (0.15 | ) | $ | (0.21 | ) | |||
Weighted-average common shares outstanding — basic and diluted | 308,254,256 | 303,773,922 | 307,972,054 | 303,336,787 |
TABLE 2
Amicus Therapeutics, Inc. Consolidated Balance Sheets (in thousands, except share and per share amounts) | |||||||
June 30, 2025 | December 31, 2024 | ||||||
Assets | |||||||
Current assets: | |||||||
Cash and cash equivalents | $ | 158,702 | $ | 213,752 | |||
Investments in marketable securities | 72,296 | 36,194 | |||||
Accounts receivable | 105,849 | 101,099 | |||||
Inventories | 154,875 | 118,782 | |||||
Prepaid expenses and other current assets | 46,285 | 34,909 | |||||
Total current assets | 538,007 | 504,736 | |||||
Operating lease right-of-use assets, net | 21,988 | 22,278 | |||||
Property and equipment, less accumulated depreciation of | 28,570 | 29,383 | |||||
Intangible assets, less accumulated amortization of | 15,570 | 17,198 | |||||
Goodwill | 197,797 | 197,797 | |||||
Other non-current assets | 13,371 | 13,641 | |||||
Total Assets | $ | 815,303 | $ | 785,033 | |||
Liabilities and Stockholders’ Equity | |||||||
Current liabilities: | |||||||
Accounts payable | $ | 13,893 | $ | 12,947 | |||
Accrued expenses and other current liabilities | 145,144 | 127,300 | |||||
Operating lease liabilities | 8,610 | 8,455 | |||||
Total current liabilities | 167,647 | 148,702 | |||||
Long-term debt | 391,322 | 390,111 | |||||
Operating lease liabilities | 43,383 | 45,078 | |||||
Other non-current liabilities | 8,647 | 7,097 | |||||
Total liabilities | 610,999 | 590,988 | |||||
Commitments and contingencies | |||||||
Stockholders’ equity: | |||||||
Common stock, | 3,016 | 2,944 | |||||
Common stock in treasury, at cost; 7,390 shares as of June 30, 2025 | (71 | ) | — | ||||
Additional paid-in capital | 2,956,839 | 2,926,115 | |||||
Accumulated other comprehensive income (loss): | |||||||
Foreign currency translation adjustment | 30,935 | 5,302 | |||||
Unrealized loss on available-for-sale securities | (129 | ) | (207 | ) | |||
Warrants | — | 71 | |||||
Accumulated deficit | (2,786,286 | ) | (2,740,180 | ) | |||
Total stockholders’ equity | 204,304 | 194,045 | |||||
Total Liabilities and Stockholders’ Equity | $ | 815,303 | $ | 785,033 |
TABLE 3
Amicus Therapeutics, Inc. Reconciliation of Non-GAAP Financial Measures (in thousands) (Unaudited) | |||||||||||
Three Months Ended June 30, | Six Months Ended June 30, | ||||||||||
2025 | 2024 | 2025 | 2024 | ||||||||
Total operating expenses - as reported GAAP | $ | 148,945 | $ | 100,441 | $ | 270,448 | $ | 224,998 | |||
Research and development: | |||||||||||
Share-based compensation | 2,393 | 3,061 | 6,397 | 7,932 | |||||||
Selling, general and administrative: | |||||||||||
Share-based compensation | 15,166 | 13,136 | 36,334 | 39,068 | |||||||
Loss on impairment of assets | 1,702 | — | 1,702 | — | |||||||
Restructuring Charges | — | — | — | 6,045 | |||||||
Depreciation and amortization | 1,852 | 2,182 | 3,689 | 4,336 | |||||||
Total operating expense adjustments to reported GAAP | 21,113 | 18,379 | 48,122 | 57,381 | |||||||
Total operating expenses - as adjusted | $ | 127,832 | $ | 82,062 | $ | 222,326 | $ | 167,617 |
TABLE 4
Amicus Therapeutics, Inc. Reconciliation of Non-GAAP Financial Measures (in thousands, except share and per share amounts) (Unaudited) | ||||||||||||||||
Three Months Ended June 30, | Six Months Ended June 30, | |||||||||||||||
2025 | 2024 | 2025 | 2024 | |||||||||||||
GAAP net loss | $ | (24,420 | ) | $ | (15,697 | ) | $ | (46,106 | ) | $ | (64,116 | ) | ||||
Share-based compensation | 17,559 | 16,197 | 42,731 | 47,000 | ||||||||||||
Depreciation and amortization | 1,852 | 2,182 | 3,689 | 4,336 | ||||||||||||
Loss on impairment of assets | 1,702 | — | 1,702 | — | ||||||||||||
Restructuring charges | — | — | — | 6,045 | ||||||||||||
Income tax expense | 5,239 | 15,805 | 8,880 | 20,641 | ||||||||||||
Non-GAAP net income | $ | 1,932 | $ | 18,487 | $ | 10,896 | $ | 13,906 | ||||||||
Non-GAAP net income attributable to common stockholders per common share — basic and diluted | $ | 0.01 | $ | 0.06 | $ | 0.04 | $ | 0.05 | ||||||||
Weighted-average common shares outstanding — basic | 308,254,256 | 303,773,922 | 307,972,054 | 303,336,787 | ||||||||||||
Weighted-average common shares outstanding — diluted | 309,651,693 | 307,022,626 | 309,520,474 | 307,598,542 |
