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I-Mab to Participate in the H.C. Wainwright “HCW@Home” Series

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I-Mab (NASDAQ: IMAB), a U.S.-based biotech company specializing in immuno-oncology, has announced its participation in the H.C. Wainwright virtual "HCW@Home" Series on June 17, 2025. The company's management team will engage in a fireside chat focused on Claudin 18.2 as a therapeutic target for gastric cancers, with particular emphasis on their drug candidate givastomig, a Claudin 18.2 x 4-1BB bispecific antibody. The discussion will feature CEO Sean Fu and CMO Phillip Dennis, moderated by H.C. Wainwright Senior Analyst Andres Maldonado. Notably, givastomig's Phase 1 dose escalation study results in combination with immunochemotherapy have been selected for presentation at the upcoming ESMO GI Cancers Congress on July 2, 2025.
I-Mab (NASDAQ: IMAB), una società biotech statunitense specializzata in immuno-oncologia, ha annunciato la sua partecipazione alla serie virtuale "HCW@Home" di H.C. Wainwright il 17 giugno 2025. Il team di gestione dell'azienda prenderà parte a una conversazione informale incentrata su Claudin 18.2 come target terapeutico per i tumori gastrici, con particolare attenzione al loro candidato farmaco givastomig, un anticorpo bispecifico Claudin 18.2 x 4-1BB. Alla discussione parteciperanno il CEO Sean Fu e il CMO Phillip Dennis, con la moderazione dell'analista senior di H.C. Wainwright Andres Maldonado. Da notare che i risultati dello studio di dose escalation di Fase 1 di givastomig in combinazione con l'immunochemioterapia sono stati selezionati per la presentazione al prossimo Congresso ESMO sui tumori gastrointestinali il 2 luglio 2025.
I-Mab (NASDAQ: IMAB), una empresa biotecnológica estadounidense especializada en inmuno-oncología, ha anunciado su participación en la serie virtual "HCW@Home" de H.C. Wainwright el 17 de junio de 2025. El equipo directivo de la compañía participará en una charla informal centrada en Claudin 18.2 como objetivo terapéutico para los cánceres gástricos, con especial énfasis en su candidato a fármaco givastomig, un anticuerpo bispecífico Claudin 18.2 x 4-1BB. La discusión contará con la presencia del CEO Sean Fu y el CMO Phillip Dennis, moderados por el analista senior de H.C. Wainwright, Andres Maldonado. Cabe destacar que los resultados del estudio de escalada de dosis de fase 1 de givastomig en combinación con inmunoquimioterapia han sido seleccionados para su presentación en el próximo Congreso ESMO de Cánceres GI el 2 de julio de 2025.
I-Mab(NASDAQ: IMAB)는 미국에 본사를 둔 면역항암 전문 바이오텍 회사로, 2025년 6월 17일 H.C. Wainwright의 가상 'HCW@Home' 시리즈에 참여한다고 발표했습니다. 회사 경영진은 위암 치료 표적으로서 Claudin 18.2에 관한 대담에 참여하며, 특히 Claudin 18.2 x 4-1BB 이중특이성 항체인 후보 약물 기바스토미그에 중점을 둘 예정입니다. 이번 토론에는 CEO Sean Fu와 CMO Phillip Dennis가 참여하며, H.C. Wainwright의 수석 분석가 Andres Maldonado가 진행을 맡습니다. 특히 기바스토미그의 면역화학요법과 병용한 1상 용량 증량 연구 결과가 2025년 7월 2일 개최되는 ESMO 위장관암 학회에서 발표될 예정입니다.
I-Mab (NASDAQ : IMAB), une entreprise biotechnologique américaine spécialisée en immuno-oncologie, a annoncé sa participation à la série virtuelle "HCW@Home" de H.C. Wainwright le 17 juin 2025. L'équipe de direction de la société participera à une discussion informelle axée sur la Claudine 18.2 en tant que cible thérapeutique pour les cancers gastriques, avec un accent particulier sur leur candidat médicament givastomig, un anticorps bispécifique Claudine 18.2 x 4-1BB. La discussion réunira le PDG Sean Fu et le directeur médical Phillip Dennis, sous la modération de l'analyste principal d'H.C. Wainwright, Andres Maldonado. Il est à noter que les résultats de l'étude de dose escalade de phase 1 de givastomig en combinaison avec l'immunochimiothérapie ont été sélectionnés pour une présentation lors du prochain Congrès ESMO sur les cancers gastro-intestinaux le 2 juillet 2025.
I-Mab (NASDAQ: IMAB), ein in den USA ansässiges Biotechnologieunternehmen, das sich auf Immunonkologie spezialisiert hat, hat seine Teilnahme an der virtuellen "HCW@Home"-Reihe von H.C. Wainwright am 17. Juni 2025 angekündigt. Das Management-Team des Unternehmens wird an einem Gespräch über Claudin 18.2 als therapeutisches Ziel für Magenkrebs teilnehmen, mit besonderem Fokus auf ihren Arzneimittelkandidaten Givastomig, einen Claudin 18.2 x 4-1BB bispezifischen Antikörper. An der Diskussion nehmen CEO Sean Fu und CMO Phillip Dennis teil, moderiert von H.C. Wainwright Senior Analyst Andres Maldonado. Bemerkenswert ist, dass die Ergebnisse der Phase-1-Dosissteigerungsstudie von Givastomig in Kombination mit Immunchemotherapie für eine Präsentation auf dem kommenden ESMO GI Cancer Congress am 2. Juli 2025 ausgewählt wurden.
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ROCKVILLE, Md., June 03, 2025 (GLOBE NEWSWIRE) -- I-Mab (NASDAQ: IMAB) (the “Company”), a U.S.-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer, today announced that I-Mab’s management team will participate in the H.C. Wainwright “HCW@Home” Series, being held virtually on Tuesday, June 17, 2025.

The discussion will cover a general overview of the Claudin 18.2 landscape as a validated therapeutic target for gastric cancers. The session will also offer a particular focus on givastomig, a potential best-in-class, Claudin 18.2 x 4-1BB bispecific antibody that is being developed in Claudin 18.2-positive gastric cancers. The Phase 1 dose escalation study of givastomig in combination with immunochemotherapy has been selected for a Mini Oral presentation at the ESMO GI Cancers Congress, scheduled for July 2, 2025.

Conference details are as follows:

H.C. Wainwright “HCW@Home with I-Mab”
Format: Fireside Chat
Moderator: Andres Maldonado, PhD, Senior Analyst, H.C. Wainwright
I-Mab Speakers:

  • Sean Fu, PhD, MBA, Chief Executive Officer
  • Phillip Dennis, MD, PhD, Chief Medical Officer

Date: Tuesday, June 17, 2025
Time: 10:00 AM to 11:00 AM ET
Webcast Link: Register here

The webcast of the event will be accessible from News & Events page of the I-Mab website for 90 days.

About I-Mab

I-Mab (NASDAQ: IMAB) is a U.S.-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer. The Company’s differentiated pipeline is led by givastomig, a potential best-in-class, bispecific antibody (Claudin 18.2 x 4-1BB) designed to treat Claudin 18.2-positive gastric cancers. Givastomig conditionally activates T cells via the 4-1BB signaling pathway in the tumor microenvironment where Claudin 18.2 is expressed. Givastomig is being developed for first-line metastatic gastric cancers, with additional potential in other solid tumors. In Phase 1 trials, givastomig was observed to maintain a strong tumor-binding property and anti-tumor activity, attributable to a potential synergistic effect of proximal interaction with Claudin 18.2 and 4-1BB, while minimizing toxicities commonly seen with other 4-1BB agents.

For more information, please visit www.i-mabbiopharma.com and follow us on LinkedIn and X.

I-Mab Forward Looking Statements

This announcement contains forward-looking statements. These statements are made under the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will”, “expects”, “believes”, “designed to”, “anticipates”, “future”, “intends”, “plans”, “potential”, “estimates”, “confident”, and similar terms or the negative thereof. I-Mab may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities and Exchange Commission (the “SEC”), in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about I-Mab’s beliefs and expectations, are forward-looking statements. Forward-looking statements in this press release include, without limitation, statements regarding: the Company’s pipeline and clinical development of I-Mab’s drug candidates, including givastomig; the projected advancement of the Company’s portfolio and anticipated milestones and related timing; the Company’s expectations regarding the impact of data from ongoing and future clinical trials the timing and progress of studies and trials (including with respect to patient enrollment); the potential benefits of givastomig; and the availability of data and information from ongoing studies and trials. Forward-looking statements involve inherent risks and uncertainties that may cause actual results to differ materially from those contained in these forward-looking statements, including but not limited to the following: I-Mab’s ability to demonstrate the safety and efficacy of its drug candidates; the clinical results for its drug candidates, which may or may not support further development or New Drug Application/Biologics License Application (NDA/BLA) approval; the content and timing of decisions made by the relevant regulatory authorities regarding regulatory approval of I-Mab’s drug candidates; I-Mab’s ability to achieve commercial success for its drug candidates, if approved; I-Mab’s ability to obtain and maintain protection of intellectual property for its technology and drugs; I-Mab’s reliance on third parties to conduct drug development, manufacturing and other services; and I-Mab’s limited operating history and I-Mab’s ability to obtain additional funding for operations and to complete the development and commercialization of its drug candidates, as well as those risks more fully discussed in the “Risk Factors” section in I-Mab’s annual report on Form 20-F filed with the SEC on April 3, 2025, as well as the discussions of potential risks, uncertainties, and other important factors in I-Mab’s subsequent filings with the SEC. All forward-looking statements are based on information currently available to I-Mab. I-Mab undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise, except as may be required by law.

I-Mab Investor & Media Contacts
PJ Kelleher
LifeSci Advisors
+1-617-430-7579
pkelleher@lifesciadvisors.com
IR@imabbio.com


FAQ

When is I-Mab (IMAB) presenting at the H.C. Wainwright conference?

I-Mab is presenting at the H.C. Wainwright 'HCW@Home' Series on Tuesday, June 17, 2025, from 10:00 AM to 11:00 AM ET.

What will I-Mab (IMAB) discuss at the H.C. Wainwright conference?

I-Mab will discuss the Claudin 18.2 landscape as a therapeutic target for gastric cancers and their drug candidate givastomig, a Claudin 18.2 x 4-1BB bispecific antibody.

Who are the speakers from I-Mab (IMAB) at the H.C. Wainwright conference?

The speakers from I-Mab are Sean Fu, PhD, MBA (Chief Executive Officer) and Phillip Dennis, MD, PhD (Chief Medical Officer).

When will I-Mab (IMAB) present givastomig's Phase 1 study results?

I-Mab will present givastomig's Phase 1 dose escalation study results at the ESMO GI Cancers Congress on July 2, 2025.

What type of drug is I-Mab's (IMAB) givastomig?

Givastomig is a potential best-in-class, Claudin 18.2 x 4-1BB bispecific antibody being developed for Claudin 18.2-positive gastric cancers.
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