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Immuron CEO, Steven Lydeamore presentation at Kalkine Media Webinar

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Immuron (NASDAQ: IMRN; ASX: IMC) announced that CEO Steven Lydeamore will present virtually at the Kalkine Media Webinar on Monday, 20 July 2026 at 12:30pm Australian Eastern Time. The accompanying slide deck is available on Immuron’s investor website.

According to Immuron, the company develops orally delivered targeted polyclonal antibodies for infectious diseases, led by Travelan (IMM‑124E) for travelers’ diarrhea, adjunctive candidate IMM‑529 for recurrent Clostridioides difficile infection, and distribution of ProIBS for irritable bowel syndrome in Australia and New Zealand.

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Positive

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Negative

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News Market Reaction – IMRN

-6.61%
4 alerts
-6.61% News Effect
-4.1% Trough Tracked
-$662K Valuation Impact
$9.35M Market Cap
1.0x Rel. Volume

On the day this news was published, IMRN declined 6.61%, reflecting a notable negative market reaction. Argus tracked a trough of -4.1% from its starting point during tracking. Our momentum scanner triggered 4 alerts that day, indicating moderate trading interest and price volatility. This price movement removed approximately $662K from the company's valuation, bringing the market cap to $9.35M at that time.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock moved -6.6% in the session following this news. The historical -5.04% reaction to FY26 sal...
Analysis

The stock moved -6.6% in the session following this news. The historical -5.04% reaction to FY26 sales growth provides a documented downside comparison for this presentation notice. The record shows that positive company disclosures have not always aligned with subsequent price reactions.

Key Figures

Primary disease prevention: 80% (P =0.0052) Disease recurrence protection: 67% (P <0.01) Primary disease treatment: 78.6% (P<0.0001) +5 more
8 metrics
Primary disease prevention 80% (P =0.0052) IMM-529 pre-clinical infection model
Disease recurrence protection 67% (P <0.01) IMM-529 pre-clinical relapse model
Primary disease treatment 78.6% (P<0.0001) IMM-529 pre-clinical infection model
ETEC strains 13 strains IMM-124E vaccine
Usability study users 1,003 users ProIBS usability study
ProIBS helpfulness 94% ProIBS usability study participants
Daily-life improvement 91% ProIBS usability study participants
Recommendation rate 98% ProIBS usability study participants

Historical Context

5 past events · Latest: Jul 16 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jul 16 FY26 sales growth Positive -5.0% Travelan sales rose 6% across four consecutive quarters of year-over-year growth.
Jul 06 IMM-529 partnering strategy Positive +1.8% Pullan Consulting was engaged to seek a strategic partner for Phase 2-ready IMM-529.
Apr 22 Research report update Positive -3.4% Research coverage maintained its rating and raised the 12-month price target.
Apr 17 Third-quarter sales growth Positive +13.3% Third-quarter sales increased 16% on the prior comparative period.
Mar 05 First-half results Positive +4.5% Revenue growth, narrowed losses, additional funding, and Phase 2 authorization were reported.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Immuron's recent positive sales and development announcements produced mixed reactions, with three aligned gains and two divergent declines.

Key Terms

passive immunotherapy, hyper-immune bovine colostrum, polyclonal immunoglobulins, proteolysis
4 terms
passive immunotherapy medical
"Travelan® is an orally administered passive immunotherapy"
Passive immunotherapy is a medical approach that gives a person ready-made antibodies or immune proteins to neutralize pathogens or diseased cells, providing immediate but usually temporary protection or treatment. It matters to investors because these therapies involve different development timelines, manufacturing needs, regulatory paths and pricing models than vaccines or small-molecule drugs—similar to renting a tool for immediate use rather than building one yourself, which affects market demand, production scale and revenue dynamics.
hyper-immune bovine colostrum medical
"derived from engineered hyper-immune bovine colostrum"
Hyper-immune bovine colostrum is the antibody-rich first milk collected from cows that have been specifically vaccinated to produce high levels of antibodies against a chosen pathogen or toxin. For investors, it matters because these concentrated, targeted antibodies can be developed as preventive supplements or treatments, and their commercial potential depends on clinical proof, regulatory approval, manufacturing scale and consistent supply—similar to assessing a drug or specialty food ingredient.
polyclonal immunoglobulins medical
"technology is based on polyclonal immunoglobulins (IgG)"
Polyclonal immunoglobulins are mixtures of antibodies produced by many different immune cells and collected from pooled blood plasma; they provide broad, ready-made immune activity rather than a single targeted antibody. They matter to investors because these biologic therapies involve complex manufacturing, donor-dependent supply chains, regulatory oversight and recurring demand for treatment of immune deficiencies and certain inflammatory conditions, which can affect revenue, costs and risk profiles for companies that make or distribute them.
proteolysis medical
"resistant to proteolysis by the digestive enzymes"
Proteolysis is the chemical process by which enzymes called proteases cut proteins into smaller peptides or amino acids, similar to scissors trimming a long chain into shorter links. It matters to investors because controlling or harnessing proteolysis influences how diseases progress, how long biologic drugs last in the body, and how new therapies (including targeted protein degradation) are developed and regulated, which can affect the commercial and scientific value of biotech assets.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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MELBOURNE, Australia, July 20, 2026 (GLOBE NEWSWIRE) -- Immuron Limited (ASX: IMC; NASDAQ: IMRN) is pleased to advise our Chief Executive Officer, Steven Lydeamore is presenting virtually at the Kalkine Media Webinar on Monday, 20th July 2026 (12:30pm Australian Eastern Time).

A copy of the presentation slide deck is available on the Company’s website:

https://investors.immuron.com.au/announcements/7639968

This release has been authorised by the directors of Immuron Limited.

COMPANY CONTACT:
Steven Lydeamore
Chief Executive Officer
steve@immuron.com        
  


About Immuron

Immuron Limited (ASX: IMC, NASDAQ: IMRN), is an Australian biopharmaceutical company focused on developing and commercializing orally delivered targeted polyclonal antibodies for the treatment of infectious diseases.

About Travelan®

Travelan® is an orally administered passive immunotherapy that prophylactically reduces the likelihood of contracting travelers’ diarrhea, a digestive tract disorder that is commonly caused by pathogenic bacteria and the toxins they produce. Travelan® is a highly purified tabletized preparation of hyper immune bovine antibodies and other factors, which when taken with meals bind to diarrhea-causing bacteria and prevent colonization and the pathology associated with travelers’ diarrhea. In Australia, Travelan® is a listed medicine on the Australian Register for Therapeutic Goods (AUST L 106709) and is indicated to reduce the risk of Travelers’ Diarrhea, reduce the risk of minor gastro-intestinal disorders and is antimicrobial. In Canada, Travelan® is a licensed natural health product (NPN 80046016) and is indicated to reduce the risk of Travelers’ Diarrhea. In the U.S., Travelan® is sold as a dietary supplement for digestive tract protection.

Travelers’ diarrhea (TD)
TD is generally defined as the passage of ≥ 3 unformed stools per 24 hours plus at least one additional symptom (such as nausea, vomiting, abdominal cramps, fever, blood/mucus in the stools, or fecal urgency) that develop while abroad or within 10 days of returning from any resource-limited destinations (Leung et al., 2006). Diarrhea continues to be the most frequent health problem among travelers to destinations in lower- and middle-income regions (Steffen, 2017). Deployed US military personnel, essentially representing a long-term traveller population, are particularly affected given their population dynamics and the context in which they seek care and treatment (Connor et al., 2012). Diarrhea is the leading infectious disease threat to the overall health and preparedness of deployed US armed forces, with diarrheagenic E. coli, Campylobacter spp., and Shigella spp. among the most commonly reported etiologies (Riddle et al., 2006).

Immuron Platform Technology

Immuron’s proprietary technology is based on polyclonal immunoglobulins (IgG) derived from engineered hyper-immune bovine colostrum. Immuron has the capability of producing highly specific immunoglobulins to any enteric pathogen and our products are orally active. Bovine IgG can withstand the acidic environment of the stomach and is resistant to proteolysis by the digestive enzymes found in the Gastrointestinal (GI) tract. Bovine IgG also possesses this unique ability to remain active in the human GI tract delivering its full benefits directly to the bacteria found there. The underlying nature of Immuron’s platform technology enables the development of medicines across a large range of infectious diseases. The platform can be used to block viruses or bacteria at mucosal surfaces such as the Gastrointestinal tract and neutralize the toxins they produce.

IMM-124E (Travelan®)

IMM-124E was developed using Immuron’s platform technology. IMM-124E is produced from the colostrum of birthing cattle that have been immunised during pregnancy with a vaccine containing the outer antigens of multiple human derived ETEC. A total of 13 ETEC strains are used in the vaccine to produce high levels of antibodies against selected surface antigens from the most common strains of ETEC. (Otto et al., 2011)

The resultant hyperimmune colostrum IMM-124E from ETEC vaccinated cows contains significant levels of polyclonal antibodies specific for ETEC antigens LPS, CFA-I and Flagellin (Sears et al., 2017).

The antibodies produced in IMM-124E have been found to have a stronger binding and neutralizing activity (than the antibodies of unvaccinated cattle) against a wide range of LPS antigens including both the variable O-polysaccharide region and the preserved oligosaccharide core ‘R’ region of LPS from the 13 serotypes used in the ETEC vaccine.

IMM-124E is manufactured into a tablet form referred to as Travelan®.

IMM-529
Immuron is developing IMM-529 as an adjunctive therapy in combination with standard of care antibiotics for the prevention and/or treatment of recurrent Clostridioides difficile infection (CDI). IMM-529 antibodies targeting Clostridioides difficile (C. diff) may help to clear CDI infection and promote a quicker re-establishment of normal gut flora, providing an attractive oral preventative for recurrent CDI.

Immuron is collaborating with Dr. Dena Lyras and her team at Monash University, Australia to develop vaccines to produce bovine colostrum-derived antibodies. Dairy cows were immunised to generate hyperimmune bovine colostrum (HBC) that contains antibodies targeting three essential C. diff virulence components. IMM-529 targets Toxin B (TcB), the spores and the surface layer proteins of the vegetative cells.

This unique 3-target approach has yielded promising results in pre-clinical infection and relapse models, including (1) Prevention of primary disease (80% P =0.0052); (2) Protection of disease recurrence (67%, P <0.01) and (3) Treatment of primary disease (78.6%, P<0.0001; TcB HBC). Importantly IMM-529 antibodies cross-react with whole cell lysates of many different human strains of C. diff including hypervirulent strains.

To our knowledge, IMM-529 is, to date, the only investigational drug that has shown therapeutic potential in all three phases of the disease (Hutton et al., 2017).

ProIBS®
Immuron has an exclusive distribution agreement with Calmino goup AB for the territories of Australia and New Zealand for ProIBS®. ProIBS® - to help patients treat IBS symptoms ProIBS® is a certified medical device for the treatment of IBS symptoms such as abdominal pain, bloating and unsettled bowel movements (diarrhoea and/or constipation). ProIBS® contains AVH200®, derived from the plant Aloe barbadensis. Mill. AVH200® has gel forming components which support the intestinal mucosal barrier. As IBS is known to affect individuals for a long period of time, it is essential to have a treatment appropriate for long-term use –as ProIBS® is. The product is safe, and no interactions with other medications are known. Science-driven innovative Calmino group AB, the developer of ProIBS®, conducted a usability study among 1,003 users. PROIBS® was helpful for 94% of them. 91% of the users experienced an improvement in daily life and 98% would recommend PROIBS® to someone else. To learn more please check: www.proibs.eu.

Irritable bowel syndrome (IBS) is a common condition where you experience symptoms related to your digestive system. This is sometimes linked to certain foods, lifestyle habits and stress levels or mood. IBS affects around 3 out of every 10 people. Females are more likely than males to be affected. Some key symptoms of IBS include: abdominal pain or discomfort; stomach bloating and wind; chronic diarrhoea or constipation, or alternating between the two.(healthdirect.gov.au) According to available data, the IBS treatment market in Australia is estimated to be a part of the broader "Digestives & Intestinal Remedies" market, generating a revenue of around AU$221.14 million in 2025, with a projected annual growth rate of 3.28%.(Statista)

References

Connor P, Porter CK, Swierczewski B and Riddle MS. Diarrhea during military deployment: current concepts and future directions. Curr Opin Infect Dis. 25(5): 546-54; 2012.

Hutton, M.L., Cunningham, B.A., Mackin, K.E. et al. Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative. Sci Rep 7, 3665 (2017). https://doi.org/10.1038/s41598-017-03982-5

Leung AK, Robson WL, Davies HD. Travelers’ diarrhea. Adv Ther. Jul-Aug; 23(4): 519-27; 2006

Otto W, Najnigier B, Stelmasiak T and Robins-Browne RM. Randomized control trials using a tablet formulation of hyperimmune bovine colostrum to prevent diarrhea caused by enterotoxigenic Escherichia coli in volunteers Scandinavian Journal of Gastroenterology 46: 862– 868; 2011.

Riddle MS, Sanders JW, Putnam SD, and Tribble DR. Incidence, etiology, and impact of diarrhea among long-term travelers’ (US military and similar populations): A systematic review. American Journal of Tropical Medicine and Hygiene. 74(5): 891-900; 2006.

Sears KT, Tennant SM, Reymann MK, Simon R, Konstantopolos N, Blackwelder WC, Barry EM and Pasetti MF. Bioactive Immune Components of Anti-Diarrheagenic Enterotoxigenic Escherichia coli Hyperimmune Bovine Colostrum products. Clinical and Vaccine Immunology. 24 (8) 1-14; 2017.

Steffen R. Epidemiology of travelers' diarrhea. J Travel Med. 24(suppl_1): S2-S5; 2017.

For more information visit: https://www.immuron.com.au/ and https://www.travelan.com
Subscribe to Immuron’s InvestorHub: Here

FORWARD-LOOKING STATEMENTS:

This press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, each as amended. Such statements include, but are not limited to, any statements relating to our growth strategy and product development programs and any other statements that are not historical facts. Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition, and stock value. Factors that could cause actual results to differ materially from those currently anticipated include: risks relating to our growth strategy; our ability to obtain, perform under and maintain financing and strategic agreements and relationships; risks relating to the results of research and development activities; risks relating to the timing of starting and completing clinical trials; uncertainties relating to preclinical and clinical testing; our dependence on third-party suppliers; our ability to attract, integrate and retain key personnel; the early stage of products under development; our need for substantial additional funds; government regulation; patent and intellectual property matters; competition; as well as other risks described in our SEC filings. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions, or circumstances on which any such statement is based, except as required by law.


FAQ

What is Immuron (NASDAQ: IMRN) presenting at the Kalkine Media Webinar on July 20, 2026?

Immuron will present an overview of its business and products at the Kalkine Media Webinar on July 20, 2026. According to Immuron, CEO Steven Lydeamore will present virtually at 12:30pm Australian Eastern Time, supported by a slide deck on the company’s investor website.

How can investors access Immuron’s July 20, 2026 Kalkine Media Webinar presentation for IMRN?

Investors can access Immuron’s July 20, 2026 webinar presentation via the slide deck on its investor website. According to Immuron, a copy of the presentation is available under announcements at https://investors.immuron.com.au/announcements/7639968 for detailed company and product information.

What is Travelan from Immuron (IMRN) and how is it used against travelers’ diarrhea?

Travelan is an orally administered product that reduces the likelihood of contracting travelers’ diarrhea. According to Immuron, it contains hyperimmune bovine antibodies that bind diarrhea-causing bacteria in the gut, preventing colonization. It is registered as a medicine in Australia and a natural health product in Canada.

What is Immuron’s IMM-529 candidate and what preclinical results have been reported?

IMM-529 is being developed as an adjunctive oral therapy for recurrent Clostridioides difficile infection. According to Immuron, preclinical models showed prevention of primary disease in 80%, protection against recurrence in 67%, and treatment of primary disease in 78.6%, targeting toxin B, spores and surface layer proteins.

What does Immuron’s platform technology focus on for IMRN shareholders?

Immuron’s platform focuses on orally delivered polyclonal immunoglobulins derived from hyperimmune bovine colostrum. According to Immuron, these antibodies remain active in the gastrointestinal tract, where they can bind enteric pathogens or toxins, supporting development of products for multiple infectious diseases affecting the gut mucosal surfaces.

What is ProIBS and how is Immuron involved in its distribution in Australia and New Zealand?

ProIBS is a certified medical device aimed at relieving IBS symptoms such as abdominal pain, bloating and irregular bowel movements. According to Immuron, it holds exclusive distribution rights for ProIBS in Australia and New Zealand under an agreement with Calmino group AB, supporting long-term IBS management.