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NexTel Medical Corp. Executes Letter of Intent to Acquire 100% of Xycota Biosciences, LLC

(Very High)
(Very Positive)

NexTel Medical (OTC: MAJI) has executed a definitive Letter of Intent to acquire 100% of Xycota Biosciences, a preclinical biotech developing non-psychoactive, exosome-delivered therapeutics to repair brain circuitry and restore synaptic connectivity in severe neurodegenerative diseases.

Xycota’s lead candidate, XYCO-01, uses proprietary fungal-derived exosome delivery to upregulate the BDNF‑TrkB neuroplasticity pathway while avoiding first-pass liver metabolism and hallucinogenic receptor activation. Xycota has applied to the FDA for Orphan Drug Designation for XYCO-01 in Frontotemporal Dementia, with issuance expected by the company. The platform is led by co-founder and CSO Dr. Marvin S. Hausman, who is credited with over 50 years of CNS drug development experience and six successful FDA NDAs, and is positioned for follow-on indications including ALS, mild traumatic brain injury and broader neurodegenerative conditions.

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Positive

  • LOI to acquire 100% of Xycota Biosciences expands NexTel’s neurodegeneration pipeline
  • Lead asset XYCO-01 targets BDNF-TrkB neuroplasticity via exosome delivery in Frontotemporal Dementia
  • Orphan Drug Designation application filed with FDA for XYCO-01 in FTD, with potential exclusivity and tax benefits
  • Experienced scientific leadership via CSO Dr. Marvin Hausman, credited with 6 prior FDA NDAs

Negative

  • Transaction at LOI stage only, with no disclosed closing terms, timing, or financial consideration
  • Xycota is preclinical, with no approved products or late-stage clinical data disclosed
  • Orphan Drug Designation for XYCO-01 is pending and not yet granted by the FDA

News Market Reaction – MAJI

+2.25%
+2.25% Session close to close

In the Aug 5 session, MAJI gained 2.25%, reflecting a moderate positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

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Strategic Acquisition Positions NexTel at the Forefront of Precision Neuro-Restoration with Xycota's Breakthrough Exosome-Delivered Brain Circuitry Repair Platform and Pending FDA Orphan Drug Designation

ORLANDO, FL / ACCESS Newswire / August 5, 2026 / NexTel Medical Corp. (f/k/a Exousia Pro, Inc.) (OTCID:MAJI), today announced that it has executed a definitive Letter of Intent (LOI) to acquire 100% of Xycota Biosciences, LLC ("Xycota"), a preclinical biotechnology platform engineering non-psychoactive, precision-targeted therapeutics to physically repair brain circuitry and restore synaptic connectivity.

Xycota is advancing a transformative biological interface designed to physically repair damaged neural networks in catastrophic neurodegenerative diseases. By utilizing proprietary fungal-derived exosome delivery systems, Xycota's lead candidate, XYCO-01, directly upregulates the BDNF-TrkB neuroplasticity signaling pathway while bypassing first-pass liver metabolism and hallucinogenic receptor activation. This paradigm-shifting approach decouples therapeutic neural restoration from psychedelic side effects, establishing a standardized, controllable mechanism for structural brain repair.

Key Regulatory & Growth Catalyst: Pending FDA Orphan Drug Designation

Xycota has formally applied for Orphan Drug Designation (ODD) with the U.S. Food and Drug Administration (FDA) for XYCO-01 in its primary indication, Frontotemporal Dementia (FTD). Official issuance of the ODD status is expected shortly. Upon designation and approval, ODD status provides seven years of U.S. market exclusivity, tax credits for qualified clinical testing, and regulatory fee exemptions, greatly accelerating the clinical and commercial development roadmap.

Cutting-Edge Scientific Foundation & Platform Synergy

Xycota's platform is anchored by peer-reviewed mechanistic evidence published in the Nature Portfolio journal Neuropsychopharmacology (Trezza, Hausman, et al., 2026 Psilocybin improves novel object recognition... through the modulation of the BDNF/TrkB signaling pathway, demonstrating that synaptic restoration and cognitive improvement can be achieved by modulating intrinsic BDNF/TrkB growth pathways. Xycota's pipeline is led by Co-Founder & Chief Scientific Officer Dr. Marvin S. Hausman, MD, who brings over 50 years of CNS drug development experience, 6 successful FDA NDAs, and a proven track record of commercial exits.

Following the initial lead indication in Frontotemporal Dementia, the platform offers rapid expansion into Amyotrophic Lateral Sclerosis (ALS), mild traumatic brain injury (mTBI), and broader neurodegenerative conditions.

"Executing this LOI to acquire 100% of Xycota Biosciences marks a defining milestone in NexTel Medical's corporate development and growth trajectory," stated Matthew Dwyer, President and Chief Executive Officer of NexTel Medical Corp. "Xycota's cutting-edge exosome delivery platform addresses immense unmet clinical needs in Frontotemporal Dementia and ALS where no restorative therapies currently exist. Combining Xycota's breakthrough neuro-restoration architecture with NexTel's commercial infrastructure creates an extraordinary, value-generative catalyst for our shareholders."

About Xycota Biosciences, LLC

Xycota Biosciences, LLC is a precision biotechnology company engineering exosome-delivered neuroplasticity therapeutics to repair brain circuitry. Anchored by peer-reviewed science and institutional leadership, Xycota is building a scalable translational platform targeting FTD, ALS, and neurodegenerative disorders. For more information, visit https://xycota.com/ and connect on LinkedIn at https://www.linkedin.com/company/xycota-biosciences.

About NexTel Medical Corp.

NexTel Medical Corp. is a medical technology and biotechnology enterprise focused on acquiring, integrating, and commercializing high-impact medical platforms, novel therapeutic delivery technologies, and healthcare innovations.

Media & Investor Contacts:

NexTel Medical Corp.
Investor Relations & Corporate Communications
Email: ir@nextelmedical.com
Website: www.nextelmedical.com

Xycota Biosciences, LLC
Brad Listermann, President & Co-Founder
Email: info@xycota.com
Website: https://xycota.com/

SOURCE: NexTel Medical Corp



View the original press release on ACCESS Newswire

FAQ

What did NexTel Medical (MAJI) announce about acquiring Xycota Biosciences on August 5, 2026?

NexTel Medical announced it executed a definitive Letter of Intent to acquire 100% of Xycota Biosciences. According to NexTel, Xycota adds a preclinical exosome-delivered neuro-restoration platform and lead candidate XYCO-01 targeting Frontotemporal Dementia and other neurodegenerative conditions.

What is Xycota Biosciences and its role in NexTel Medical’s (MAJI) strategy?

Xycota Biosciences is a precision biotech engineering exosome-delivered neuroplasticity therapeutics to repair brain circuitry. According to NexTel, acquiring Xycota would integrate a scalable platform targeting FTD, ALS, mild traumatic brain injury and broader neurodegenerative disorders into NexTel’s medical technology and biotechnology portfolio.

What is XYCO-01 in the NexTel Medical (MAJI) and Xycota acquisition announcement?

XYCO-01 is Xycota’s lead preclinical candidate delivered via proprietary fungal-derived exosomes to upregulate the BDNF-TrkB neuroplasticity pathway. According to NexTel, this approach aims to restore synaptic connectivity while bypassing first-pass liver metabolism and psychedelic receptor activation in severe neurodegenerative diseases.

Has XYCO-01 received FDA Orphan Drug Designation in NexTel Medical’s (MAJI) deal with Xycota?

XYCO-01 has not yet received Orphan Drug Designation; Xycota has formally applied to the FDA for Frontotemporal Dementia. According to NexTel, official issuance is expected, and designation could provide seven years’ U.S. market exclusivity, tax credits, and regulatory fee exemptions.

How could the planned Xycota acquisition impact NexTel Medical (MAJI) shareholders?

The Letter of Intent could add a novel neuro-restoration platform and multiple potential indications to NexTel’s pipeline. According to NexTel, combining Xycota’s exosome technology with NexTel’s commercial infrastructure is intended as a value-generative catalyst, though financial terms and closing details were not disclosed.

What stage is the NexTel Medical (MAJI) acquisition of Xycota Biosciences at now?

The transaction is currently at the definitive Letter of Intent stage; a completed acquisition has not been announced. According to NexTel, the LOI covers acquiring 100% of Xycota, but specific closing timelines, conditions, and consideration have not been detailed publicly.

Who is leading the scientific development at Xycota in NexTel Medical’s (MAJI) proposed acquisition?

Scientific development at Xycota is led by co-founder and Chief Scientific Officer Dr. Marvin S. Hausman. According to NexTel, he brings over 50 years of CNS drug development experience, six successful FDA new drug applications, and a history of commercial exits to the platform.