STOCK TITAN

Seres Therapeutics to Present at CARB-X Investor Day

(Neutral)
Tags

Seres Therapeutics (Nasdaq: MCRB) will present at the CARB-X Investor Day on April 16, 2026, ahead of ESCMID in Munich. Elizabeth Halvorsen, Ph.D., will overview Seres’ therapeutic platform and its CARB-X collaboration. In 2025 Seres received up to $3.6 million from CARB-X to advance SER-428, an oral liquid formulation derived from SER-155 strains, and is designing a Phase 1b open-label trial in medical ICU patients.

Loading...
Loading translation...

Positive

  • None.

Negative

  • None.

News Market Reaction – MCRB

-0.57%
1 alert
-0.57% Session close to close
$87.43M Market Cap
0.5x Rel. Volume

In the Apr 9 session, MCRB declined 0.57%, reflecting a mild negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights Seres’ continued engagement with CARB-X and progress on SER-428, an ora...
Analysis

This announcement highlights Seres’ continued engagement with CARB-X and progress on SER-428, an oral liquid formulation targeting high-risk ICU patients who cannot take capsules. The non-dilutive CARB-X award of up to $3.6 million supports development and a planned Phase 1b trial. In context of a Phase 2–ready SER-155 program and earlier inflammatory and immune disease efforts, investors may watch for trial initiations, additional partnerships, and clarity on broader pipeline prioritization.

Key Figures

CARB-X award: $3.6 million Projected AMR deaths: 10 million per year Award year: 2025 +2 more
5 metrics
CARB-X award $3.6 million Non-dilutive funding in 2025 to support SER-428 development
Projected AMR deaths 10 million per year World Health Organization estimate by 2050 for antimicrobial resistance
Award year 2025 Year Seres received its second CARB-X non-dilutive award
Phase 1b trial Phase 1b Open-label ICU trial design for SER-428 in high-risk patients
SER-155 status Phase 2 ready Program to reduce bloodstream infections in allo-HSCT patients

Historical Context

5 past events · Latest: Mar 12 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 12 Earnings and updates Positive +1.3% Reported 2025 results, highlighted SER-155 data timeline and cash runway into Q3 2026.
Mar 02 Management change Neutral -1.8% Appointed interim CEO and refocused on inflammatory and immune disease biotherapeutics.
Feb 12 Program reprioritization Negative -41.7% Paused SER-155 Phase 2 allo-HSCT, implemented ~30% workforce reduction to extend runway.
Jan 06 Clinical publications Positive +2.4% Published VOWST mechanism data and highlighted SER-155’s 77% bloodstream infection reduction.
Nov 24 Conference participation Neutral -4.2% Announced participation in Piper Sandler healthcare conference and webcast availability.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent stock reactions have generally aligned with the tone of major business and scientific updates, while neutral conference/management items have sometimes seen negative moves.

Recent Company History

Over the past months, Seres has pivoted toward early-stage microbiome programs while managing funding constraints. On Jan 6, positive VOWST mechanism and SER-155 data saw a +2.37% move. A strategic reprioritization and cost-cut on Feb 12 led to a sharp -41.66% reaction. Subsequent management and earnings updates in March produced modest mixed moves. Today’s CARB-X Investor Day presentation fits the pattern of visibility-focused news alongside ongoing development of SER-428 and SER-155.

Key Terms

antimicrobial resistance, AMR, Phase 1b, allogeneic hematopoietic stem cell transplant, +4 more
8 terms
antimicrobial resistance medical
"working to combat antimicrobial resistance (AMR). The World Health Organization"
Antimicrobial resistance is when microbes such as bacteria, viruses or fungi evolve so that medicines meant to kill them no longer work — like a lock changing so the old key no longer fits. For investors, this increases demand and cost for new treatments, prolongs hospital stays, prompts tougher regulation and can shrink sales of once-effective drugs, affecting pharmaceutical revenues, R&D spending and broader healthcare risk.
AMR medical
"patients at high risk of AMR infections. Seres has advanced development"
Antimicrobial resistance (AMR) is when bacteria, viruses or other microbes evolve so the drugs designed to stop them no longer work, often because of genetic changes and overuse of treatments. For investors, AMR reshapes healthcare demand and regulation: it raises treatment costs, drives demand for new drugs, diagnostics and hospital measures, and creates long-term market opportunities and risks—like a widening pothole that forces industry-wide rerouting and repair.
Phase 1b medical
"designing a Phase 1b open label trial in collaboration with Dr."
"Phase 1b" is an early stage in testing a new medical treatment or vaccine, where it is given to a small group of people to evaluate its safety and determine the right dose. For investors, this phase signals progress in development, indicating the treatment is advancing through initial safety checks, which can influence expectations for future success and potential market impact.
allogeneic hematopoietic stem cell transplant medical
"in patients undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT)."
A treatment that replaces a patient’s blood-forming cells with stem cells taken from a genetically matched donor, used to rebuild the immune and blood system after disease or intensive therapy. Think of it like re-seeding a damaged lawn with grass from a healthy yard; it can restore function but carries risks such as immune reactions and serious complications. Investors track this procedure because its effectiveness, safety profile, supply constraints and reimbursement drive demand for related drugs, devices and services and can materially affect company value.
allo-HSCT medical
"life-threating bloodstream infections in patients undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT)."
Allo-HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically matched donor to replace a diseased or damaged bone marrow, often used for blood cancers and immune disorders. For investors, it matters because demand and outcomes for this complex, high-cost treatment affect hospital and clinic revenue, the market for supportive drugs and cell therapies, and the commercial value of companies developing safer transplants, donor matching tools, or complications treatments — like replacing a failing engine with a donated one and tracking the market for parts and repairs.
irEC medical
"immune diseases including inflammatory bowel disease (IBD) and immune checkpoint inhibitor-related enterocolitis (irEC)"
I-REC (International Renewable Energy Certificate) is a tradable certificate that proves one megawatt-hour of electricity was generated from renewable sources. Think of it like a receipt for clean power that companies can buy to show they are using greener energy; investors watch I-REC use because it signals a company's environmental commitments, can affect operating costs, regulatory compliance, and brand value, and may influence long-term risk and valuation.
medical ICU medical
"such as intubated patients in the medical ICU, and other medically vulnerable"
An intensive care unit (ICU) is a hospital ward that provides continuous, high-level monitoring and life-support treatment for patients with severe or life-threatening illnesses or injuries. For investors, ICU use is a key indicator of healthcare demand and cost pressure—higher ICU admissions can signal greater spending on complex care, strain on hospital capacity, and implications for medical equipment, staffing needs, and reimbursement rates, much like a stressed machine needing specialized service.

AI-generated analysis. How Rhea-AI works. Not financial advice.

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google
Add on Google

CAMBRIDGE, Mass., April 09, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB), (Seres or the Company), a leading live biotherapeutics company, today announced that it will present at the 2026 CARB-X Investor Day on April 16, 2026, which precedes the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Global conference in Munich, Germany. CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator) is a global nonprofit partnership accelerating the development of new antibacterial products to address drug-resistant bacteria. The CARB-X Investor Day brings together pharmaceutical and biotech product developers, investors, and partners working to combat antimicrobial resistance (AMR). The World Health Organization declared AMR as a top ten global public health threat, with estimates that yearly deaths may reach 10 million by 2050, putting mortality due to AMR on par with deaths due to cancer. The event will feature presentations on innovative therapeutics from recipients of CARB-X grants, providing opportunities for collaboration and funding support.

At the meeting, Elizabeth Halvorsen, Ph.D., Senior Director of Translational Biology at Seres, will provide an overview of the Company’s therapeutic platform and the productive, long-term collaboration with CARB-X. In 2025, Seres received a non-dilutive award from CARB-X for up to $3.6 million, representing the Company’s second CARB-X award, to support development of an oral liquid formulation based on SER-155 strains, now referred to as SER-428, for dosing in patients who cannot take oral capsules such as intubated patients in the medical ICU, and other medically vulnerable patients at high risk of AMR infections. Seres has advanced development and manufacturing of SER-428 and is designing a Phase 1b open label trial in collaboration with Dr. Dan Freedberg at Columbia University to evaluate this therapeutic candidate in medical ICU patients at high risk of infection.

“We are pleased to continue our collaboration with CARB-X, whose support has been instrumental in advancing our efforts to address antimicrobial resistance,” said Matthew Henn, Ph.D., President and Chief Scientific Officer of Seres. “We are advancing SER-428, a liquid-formulation biotherapeutic designed to expand access to vulnerable patients, including those unable to take oral capsules. We believe SER-428 can play an important role in preventing and treating antimicrobial resistance and other serious infections in ICU patients, and, with CARB-X support, are progressing toward clinical studies in high-risk populations.”

Seres continues to work to create meaningful partnerships with collaborators to support further development of its pipeline programs in inflammatory and immune diseases including inflammatory bowel disease (IBD) and immune checkpoint inhibitor-related enterocolitis (irEC), and for its Phase 2 ready SER-155 program to reduce life-threating bloodstream infections in patients undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT).

About Seres Therapeutics
Seres Therapeutics, Inc. (Nasdaq: MCRB) is a clinical-stage biotechnology company developing novel live biotherapeutics, with a focus on inflammatory and immune diseases. The Company led the development and FDA approval of VOWST™, the first orally administered microbiome therapeutic, which was subsequently divested to Nestlé Health Science. SER-155, which has received Breakthrough Therapy and Fast Track designations, is being advanced for patients undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT), and is Phase 2 ready, pending receipt of funding. An investigator-sponsored trial of SER-155 is ongoing in immune checkpoint inhibitor–related enterocolitis (irEC) to further evaluate the potential breadth of the Company’s live biotherapeutic platform. SER-603, in development for irritable bowel disease, is designed to modulate the gastrointestinal microbiome and support mucosal barrier integrity by targeting inflammatory bacteria and associated metabolites. For more information, please visit www.serestherapeutics.com.

Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including statements about: upcoming presentations and conferences; CARB-X funding and its intended uses and benefits; potential accessibility for patients; the design, timing and results of our clinical studies and data readouts; current or future product candidates and their potential impacts and outcomes; clinical development plans and commercial opportunities; our efforts to create a strategic, R&D, or other partnership; our ability to operationalize a study upon receipt of any financing; our planned strategic focus; the anticipated timing of any of the foregoing; and other statements that are not historical fact. 

These forward-looking statements are based on management’s current expectations. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, the following: (1) our need for additional funding; (2) our ability to continue as a going concern; (3) we have incurred significant losses, are not currently profitable and may never become profitable; (4) our cost reduction actions may not achieve their intended benefits, including an extended cash runway; (5) our limited operating history; (6) the expected payments from the VOWST sale are subject to risks and uncertainties; (7) we may not be able to realize the anticipated benefits of the VOWST sale, and may face new challenges as a smaller, less diversified company; (8) we have in the past and may in the future receive notice of the failure to satisfy a continued listing rule from The Nasdaq Stock Market LLC; (9) our novel approach to therapeutic intervention; (10) our reliance on third parties to conduct our clinical trials and manufacture our product candidates; (11) our ability to achieve market acceptance necessary for commercial success; (12) the competition we will face; (13) our ability to protect our intellectual property; (14) impact of our recent management transitions and appointments and our ability, to retain key personnel; and (15) disruptions at the FDA or other government agencies. These and other important factors discussed under the caption “Risk Factors” in our Annual Report on Form 10-K filed with the Securities and Exchange Commission (SEC) on March 12, 2026, as well as our other reports filed with the SEC, could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management’s estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, we disclaim any obligation to do so, even if subsequent events cause our views to change. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release.

Investor and Media Contact:

IR@serestherapeutics.com

Carlo Tanzi, Ph.D.
Kendall Investor Relations
ctanzi@kendallir.com


FAQ

When will Seres (MCRB) present at CARB-X Investor Day and where is the event?

Seres will present on April 16, 2026 at the CARB-X Investor Day in Munich. According to the company, the event precedes the ESCMID global conference and gathers developers, investors, and partners focused on antimicrobial resistance.

What funding did Seres (MCRB) receive from CARB-X and what is it for?

Seres received a non-dilutive award of up to $3.6 million from CARB-X in 2025. According to the company, funds support development of an oral liquid formulation, SER-428, based on SER-155 strains for patients who cannot take capsules.

What is SER-428 and which patients is Seres (MCRB) targeting?

SER-428 is a liquid formulation of SER-155 strains intended for patients unable to take oral capsules. According to the company, it targets intubated and other medically vulnerable ICU patients at high risk of antimicrobial resistance infections.

Does Seres (MCRB) plan clinical studies for SER-428 and with whom?

Seres is designing a Phase 1b open-label trial to evaluate SER-428 in medical ICU patients. According to the company, the study is being planned in collaboration with Dr. Dan Freedberg at Columbia University.

What other programs will Seres (MCRB) discuss or advance alongside SER-428?

Seres plans to discuss broader pipeline efforts including Phase 2-ready SER-155 and programs for IBD and irEC. According to the company, SER-155 aims to reduce life-threatening bloodstream infections in allo-HSCT patients.