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Milestone Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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Milestone Pharmaceuticals (Nasdaq: MIST) granted a total of 30,000 stock options as inducement awards to two newly hired employees under its 2021 Inducement Plan, with a grant date of December 1, 2025.

The options have an exercise price of $2.69 per share (equal to the closing price on the grant date) and vest over four years: 25% at the one-year anniversary and the remainder in 36 equal monthly installments. Awards are subject to continuous service and standard plan terms and were made in accordance with Nasdaq Listing Rule 5635(c)(4).

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Positive

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Negative

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News Market Reaction

-1.49%
1 alert
-1.49% News Effect

On the day this news was published, MIST declined 1.49%, reflecting a mild negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Inducement options: 30,000 options Exercise price: $2.69 per share Vesting period: 4 years +4 more
7 metrics
Inducement options 30,000 options Granted under 2021 Inducement Plan to two new employees
Exercise price $2.69 per share Option exercise price equal to Dec 1, 2025 close
Vesting period 4 years 25% after one year, remainder over 36 monthly installments
Net loss Q3 2025 $11.9 million Quarter ended September 30, 2025 (10-Q)
Net loss 9M 2025 $45.6 million Nine months ended September 30, 2025 (10-Q)
Cash & investments $82.6 million Cash, equivalents and short-term investments as of Sept 30, 2025
Senior convertible notes $56.2 million Net carrying amount as of Sept 30, 2025 (10-Q)

Market Reality Check

Price: $2.05 Vol: Volume 7,347,512 vs 20-da...
high vol
$2.05 Last Close
Volume Volume 7,347,512 vs 20-day average 3,842,644 (relative volume 1.91x) ahead of this routine HR-related grant news. high
Technical Price $2.95 is trading above the 200-day MA of $1.74 and sits 6.5% above the 52-week high reference.

Peers on Argus

MIST was up 1.52% while close peers were mixed: ACOG -2.83%, VTYX -1.16% (with s...

MIST was up 1.52% while close peers were mixed: ACOG -2.83%, VTYX -1.16% (with separate news and a -15.35% reaction), CYBN +4.83%, GLSI +10.93%, KYTX +3.21%, suggesting stock-specific dynamics rather than a sector-wide move.

Historical Context

5 past events · Latest: Dec 02 (Neutral)
Pattern 5 events
Date Event Sentiment Move Catalyst
Dec 02 Inducement grants Neutral -1.5% 30,000 stock options granted as inducement awards to two new hires.
Nov 12 Earnings and update Positive +1.1% Q3 2025 results, cash of $82.6M and PDUFA date for CARDAMYST.
Nov 04 Inducement grants Neutral -2.2% 65,000 stock options granted under 2021 Inducement Plan for new hires.
Nov 03 Clinical data update Positive -3.6% Pooled etripamil PSVT data showing consistent efficacy and safety across trials.
Oct 09 Conference presentation Neutral +4.5% Announcement of upcoming AHA 2025 poster on etripamil efficacy and safety.
Pattern Detected

Recent inducement grant announcements have been neutral in tone and followed by modest single-digit percentage price moves, while clinical data news has occasionally seen negative price reactions despite positive efficacy and safety descriptions.

Recent Company History

Over the last few months, Milestone has combined routine HR-related inducement grants with significant clinical and regulatory progress. Inducement option grants on Nov 3, 2025 and Dec 1, 2025 produced small single-day moves of -2.17% and -1.49%, respectively. In contrast, a Q3 2025 update on Nov 12, 2025 highlighted $82.6 million in cash and an upcoming Dec 13, 2025 PDUFA date. Pooled etripamil data presented around AHA Sessions, with 622 patients and favorable efficacy, drew a -3.65% move on Nov 3, 2025, while an earlier conference poster announcement on Oct 9, 2025 coincided with a +4.5% reaction.

Market Pulse Summary

This announcement details a routine HR-related equity grant: 30,000 stock options at a $2.69 exercis...
Analysis

This announcement details a routine HR-related equity grant: 30,000 stock options at a $2.69 exercise price, vesting over 4 years under Nasdaq Listing Rule 5635(c)(4). It follows earlier inducement grants and sits against a backdrop of sizeable net losses but cash of $82.6 million and senior secured convertible notes of $56.2 million as of September 30, 2025. Investors tracking dilution and governance may watch future equity compensation levels and how they interact with ongoing regulatory and clinical milestones.

Key Terms

nasdaq listing rule 5635(c)(4)
1 terms
nasdaq listing rule 5635(c)(4) regulatory
"in accordance with Nasdaq Listing Rule 5635(c)(4). The Plan is used..."
NASDAQ Listing Rule 5635(c)(4) is a rule that requires a company to get approval from its shareholders before selling a large amount of its shares, usually over 20%. This helps protect investors by making sure the company doesn't flood the market with new shares without their say, which could lower the stock's value.

AI-generated analysis. Not financial advice.

MONTREAL and CHARLOTTE, N.C., Dec. 02, 2025 (GLOBE NEWSWIRE) -- Milestone Pharmaceuticals Inc. (Nasdaq: MIST) (the “Company” or “Milestone”), today announced that the Company granted equity awards, in the form of a total of 30,000 options (the “Options”) to purchase the Company’s common shares, pursuant to the Company’s 2021 Inducement Plan (the “Plan”), previously approved by the Company’s Compensation Committee and the Board of Directors, as a material inducement to the hiring of two new employees. 

The Options have a grant date of December 1, 2025, and an exercise price of $2.69 per share, which is equal to the closing price of Milestone’s common shares on the grant date. The shares subject to the Options will vest over four years, with 25% of the shares vesting on the one-year anniversary of the vesting commencement date and the balance of the shares vesting in a series of 36 successive equal monthly installments thereafter.

The Option awards are subject to the award holder’s continuous service through each vesting date and to the terms and conditions of the Plan and its standard forms of grant agreements thereunder.

The foregoing equity award was granted as an inducement material to the employee entering into employment with Milestone, in accordance with Nasdaq Listing Rule 5635(c)(4). The Plan is used exclusively for the grant of equity awards to individuals who were not previously employees of Milestone, or following a bona fide period of non-employment, as an inducement material to such individual’s entering into employment with Milestone, pursuant to Nasdaq Listing Rule 5635(c)(4).

About Milestone Pharmaceuticals

Milestone Pharmaceuticals Inc. (Nasdaq: MIST) is a biopharmaceutical company developing and commercializing innovative cardiovascular solutions to improve the lives of people living with complex and life-altering heart conditions. The Company’s focus on understanding unmet patient needs and improving the patient experience has led us to develop new treatment approaches that provide patients with an active role in self-managing their care. Milestone's lead investigational product is etripamil, a novel calcium channel blocker nasal spray that is being studied for patients to self-administer without medical supervision to treat symptomatic episodic attacks associated with PSVT and AFib-RVR.

Contact:
Kevin Gardner kgardner@lifesciadvisors.com


FAQ

What did Milestone Pharmaceuticals (MIST) announce on December 2, 2025?

Milestone announced it granted 30,000 stock options as inducement awards to two new hires, with a grant date of Dec 1, 2025.

What is the exercise price of the MIST inducement options granted Dec 1, 2025?

The options have an exercise price of $2.69 per share, equal to Milestone’s closing price on the grant date.

How do the MIST options granted under the 2021 Inducement Plan vest?

Options vest over four years: 25% after one year, then the balance in 36 equal monthly installments, subject to continuous service.

Why did Milestone use the 2021 Inducement Plan for the MIST options?

The Plan is used to grant equity to individuals not previously employees (or after bona fide non‑employment) as a material inducement under Nasdaq Listing Rule 5635(c)(4).

How many employees received inducement options from Milestone (MIST)?

The company granted the 30,000 options as a material inducement to the hiring of two new employees.

Are the MIST option awards conditional on continued employment?

Yes; the awards are subject to the award holder’s continuous service through each vesting date and the Plan’s standard grant terms.
Milestone Pharmaceuticals

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