NextCure Provides Business Update and Reports Third Quarter 2026 Financial Results
Existing holders are expected to receive rights tied to legacy assets while retaining minority ownership in the combined company.
Sentiment and the balance of points
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Rhea-AI Summary
NextCure (NXTC) advanced its proposed merger with Avere Therapeutics, supported by approximately $820 million in committed financing, and reported quarterly results. Commitments comprise a $320 million concurrent private placement and an additional $500 million placement, including approximately $266 million satisfied through contribution and cancellation of Avere convertible notes. Stockholders will vote December 9, 2026; approval remains pending. Existing holders are expected to retain minority ownership and receive contingent value rights tied to specified legacy assets.
Third-quarter net loss narrowed to $6.846 million from $8.624 million a year earlier. Cash, equivalents and marketable securities fell to $8.728 million from $41.818 million at year-end. LigaChem assumed LNCB74 program costs incurred from July 1, 2026, and completed the regulatory transfer October 6. NextCure completed workforce reductions, lease terminations and asset disposals.
How this balance works
Rhea-AI gives every point it takes from this document a weight. Minor counts 1, Moderate 3 and Major 9, so one Major point outweighs several Minor ones. The bar adds up the weights on each side, and when neither side holds more than 65% of the total the balance reads Mixed.
It reads the document as published, with the same rules for every company, and it does not look at what the market expected or at how the stock traded, so a point can be objectively good on a day the stock falls.
Rhea-AI Sentiment measures something else, the tone of the wording.
Hollow bars mark forward-looking points. How the balance works
Positive
- Major point. Forward-looking: it has not happened yet and may not happen.Approximately $820 million committed financing comprises $320 million and $500 million placements, including approximately $266 million in note cancellation. 29× market cap
- Moderate pointForm S-4 effectiveness on November 6, 2026 advanced the proposed merger.
- Moderate pointFinal court order validated the July 2025 reverse split amendment and related shares on November 2, 2026.
- Moderate pointLigaChem assumed all LNCB74 program costs incurred from July 1, 2026; NextCure transition support is reimbursed.
- Moderate point. Forward-looking: it has not happened yet and may not happen.Completed restructuring reduced future operating cash requirements through workforce reductions, lease terminations and asset disposals.
- Moderate pointThird-quarter net loss narrowed to $6.846 million from $8.624 million; nine-month loss narrowed to $31.534 million from $46.408 million.
10 minor points
- Minor point. Forward-looking: it has not happened yet and may not happen.Contingent value rights tied to specified legacy assets are expected for existing NextCure stockholders.
- Minor pointLNCB74 regulatory transfer to LigaChem was completed October 6, 2026.
- Minor point. Forward-looking: it has not happened yet and may not happen.LNCB74 milestones and royalties remain potential receipts, expected to support legacy CVRs subject to their terms.
- Minor point. Forward-looking: it has not happened yet and may not happen.Legacy asset monetization remains under evaluation, including partnering or licensing SIM0505 rights.
- Minor pointLoss per share narrowed to $1.29 from $3.22 quarterly; nine-month loss narrowed to $5.97 from $18.84.
- Minor pointR&D expenses fell to $4.535 million from $6.136 million quarterly; nine-month expenses fell to $18.794 million from $38.123 million.
- Minor pointOperating loss narrowed to $6.919 million from $8.945 million quarterly; nine-month loss narrowed to $32.118 million from $47.859 million.
- Minor pointQuarterly restructuring gains, net totaled $2.044 million, versus no restructuring charge a year earlier.
- Minor pointAccounts payable and accrued liabilities declined to $4.197 million from $10.566 million at December 31, 2025.
- Minor pointATM equity sales provided $1.2 million in net proceeds; fixed-asset sales provided $0.7 million.
Negative
- Major point. Forward-looking: it has not happened yet and may not happen.Existing NextCure holders are expected to retain only a minority ownership interest after the merger.
- Moderate pointCash, equivalents and marketable securities fell to $8.728 million from $41.818 million at December 31, 2025.
- Minor pointMerger completion remains subject to stockholder approval at the December 9, 2026 meeting.
- Minor pointOperating cash use of $35.2 million primarily drove the decline in liquidity.
- Minor pointG&A expenses rose to $4.428 million from $2.809 million quarterly; nine-month expenses rose to $10.291 million from $9.736 million.
5 minor points
- Minor pointNine-month restructuring and impairment charges, net totaled $3.033 million, versus none a year earlier.
- Minor pointOther income, net fell to $73,000 from $321,000 quarterly; nine-month income fell to $584,000 from $1.451 million.
- Minor pointTotal assets fell to $9.700 million from $50.183 million at December 31, 2025.
- Minor pointStockholders’ equity fell to $5.503 million from $34.943 million at December 31, 2025.
- Minor pointATM equity issuance raised funds by issuing shares, diluting existing holders.
News Explained
The court order validates the reverse-split amendment and shares issued in reliance on it.
The merger remains proposed: the SEC declared its Form S-4 registration statement effective on
A Delaware court order dated
Key Figures
- Committed merger financing
- Approximately $820 million
- Supporting the proposed merger
- Previously announced private placement
- $320 million
- Component of the merger financing
- Additional private placement
- $500 million
- Component of the merger financing
- Convertible notes contribution and cancellation
- Approximately $266 million
- To be satisfied through contribution and cancellation of Avere notes
- Stockholder vote
- December 9, 2026
- Special meeting to consider merger-related proposals
- Cash, cash equivalents, and marketable securities
- $8.7 million vs. $41.8 million
- September 30, 2026 vs. December 31, 2025
- Cash used to fund operations
- $35.2 million
- Nine months ended September 30, 2026
- Net loss
- $6.8 million vs. $8.6 million
- Three months ended September 30, 2026 vs. 2025
Previous Earnings Reports
-
Q2 update recorded the initial $320 million Avere financing; the current update reports expanded commitments.
24h Move is the share-price change in the day after each event; other market factors may also have contributed.
Key Terms
private placement financial
convertible notes financial
at-the-market financial
investigational new drug application regulatory
contingent value rights financial
AI-generated analysis. How Rhea-AI works. Not financial advice.
- Advancing Toward Stockholder Approval of Proposed Merger with Avere Therapeutics Supported by Approximately
$820 Million of Committed Financing - S-4 Declared Effective by SEC; Stockholder Vote Scheduled for December 9, 2026
BALTIMORE, Md., Nov. 10, 2026 (GLOBE NEWSWIRE) -- NextCure, Inc. (Nasdaq: NXTC), today provided a business update and reported financial results for the third quarter ended September 30, 2026.
The Company continues to advance its proposed merger (the “Merger”) with Avere Therapeutics, Inc., a privately held biotechnology company focused on oral therapies for IL-23-driven inflammatory diseases (“Avere”), which is now supported by approximately
"During the third quarter, we continued to execute on the strategic initiatives associated with our proposed merger with Avere Therapeutics,” said Michael Richman, President and CEO of NextCure. "Importantly, total financing commitments supporting the proposed transaction increased to approximately
Recent Business Highlights
Proposed Merger with Avere
- Financing commitments supporting the Merger increased to approximately
$820 million , consisting of the previously announced$320 million concurrent private placement and an additional$500 million private placement, of which approximately$266 million will be satisfied through the contribution and cancellation of Avere’s outstanding convertible notes. - The financing is supported by a syndicate of leading healthcare-focused and institutional investors and is expected to provide substantial capital to advance development of AVR-001 and support future operations of the combined company.
- Subject to stockholder approval and other customary closing conditions, the combined company is expected to operate as Avere and trade on the Nasdaq Global Select Market (Nasdaq) under the ticker symbol "AVRX."
- On November 2, 2026, the Delaware Court of Chancery entered a final order validating the Company's July 2025 reverse stock split amendment and all shares issued in reliance thereon.
- On November 6, 2026, the Registration Statement on Form S-4 relating to the proposed merger was declared effective by the Securities and Exchange Commission (“SEC”). The Company established November 3, 2026 as the record date and scheduled a special meeting of stockholders for December 9, 2026 at 9:00 a.m. Eastern Time to consider and vote upon the proposals necessary to complete the merger.
- Existing NextCure stockholders are expected to retain an ownership interest in the combined company and receive contingent value rights (“CVRs”) tied to specified legacy NextCure assets.
LNCB74 Transition and Corporate Restructuring
- In August 2026, NextCure and LigaChem Biosciences, Inc. (“LigaChem”) entered into a Transition and Continuation Agreement pursuant to which LigaChem elected to become the sole developing party for the LNCB74 program (“LNCB74”) and assumed responsibility for all program costs incurred on or after July 1, 2026, with NextCure providing transition support reimbursed by LigaChem.
- On October 6, 2026, the parties completed the transfer of the LNCB74 investigational new drug application (IND) and related regulatory responsibilities to LigaChem.
- NextCure remains eligible to receive future development, regulatory and commercial milestone payments, as well as royalties on potential future net sales of LNCB74. Subject to the terms of the proposed contingent value rights arrangement, these economic interests are expected to be included in the legacy assets supporting the CVRs to be issued to pre-Merger NextCure stockholders.
- During the third quarter, the Company completed significant restructuring initiatives, including workforce reductions, termination of facility leases and disposition of all laboratory, manufacturing and facility-related assets, resulting in substantial reduction to the Company’s future operating cash requirements.
Strategic Alternatives for Legacy Assets
- The Company completed treatment and transition activities for patients enrolled in the SIM0505 clinical study by August 31, 2026 and continues to evaluate opportunities to partner, license or otherwise monetize rights associated with the program.
- The Company continues to evaluate strategic alternatives to derive value from its legacy asset portfolio for stockholders, including potential licensing, partnering and other opportunities.
Financial Results for the Quarter Ended September 30, 2026
- Cash, cash equivalents, and marketable securities as of September 30, 2026 were
$8.7 million , compared to$41.8 million as of December 31, 2025. The decrease of$33.1 million was primarily attributable to cash used to fund operations of$35.2 million , partially offset by$1.2 million of net proceeds from equity sales under the Company's existing at-the-market (ATM) program and$0.7 million from the sale of fixed assets. - Research and development expenses were
$4.5 million for the three months ended September 30, 2026, compared to$6.1 million for the three months ended September 30, 2025. The decrease of$1.6 million was primarily attributable to lower personnel costs resulting from the Company's restructuring initiatives, lower laboratory services and supplies costs and lower depreciation expense following the disposition of all the Company’s fixed assets. - General and administrative expenses were
$4.4 million for the three months ended September 30, 2026, compared to$2.8 million for the three months ended September 30, 2025. The increase of$1.6 million was primarily attributable to$1.8 million of higher legal and professional fees incurred in connection with the Merger. - Restructuring and asset impairment charges, net were (
$2.0) million for the three months ended September 30, 2026 and included a gain of$3.4 million on the termination of our leases and a gain of$0.4 million on the sale of fixed assets, partially offset by severance charges of$1.8 million associated with our restructuring initiatives. - Net loss was
$6.8 million for the three months ended September 30, 2026, compared to a net loss of$8.6 million for the three months ended September 30, 2025. The improvement was primarily driven by the lower research and development expenses mentioned above and$2.0 million of gains, net associated with the Company’s restructuring activities, partially offset by the higher general and administrative expenses mentioned above.
About the Merger
On July 14, 2026, NextCure announced a definitive merger agreement with Avere.
On November 2, 2026, the Delaware Court of Chancery entered a final order validating the Company's July 2025 reverse stock split amendment and all shares issued in reliance thereon.
On November 6, 2026, the Registration Statement on Form S-4 relating to the proposed merger was declared effective by the SEC. NextCure commenced distribution of definitive proxy materials and established November 3, 2026 as the record date for the special meeting of stockholders scheduled for December 9, 2026 at 9:00 a.m. Eastern Time.
Since announcement of the transaction, total financing commitments supporting the Merger have increased to approximately
Assuming the Merger is completed, the combined company is expected to operate as Avere and trade on the Nasdaq under the ticker symbol "AVRX." Existing NextCure stockholders are expected to receive contingent value rights related to specified legacy NextCure assets and retain a minority ownership interest in the combined company.
Completion of the Merger remains subject to stockholder approval and other customary closing conditions. NextCure has set a special stockholder meeting date of December 9, 2026 to vote on approval of the various Merger-related items.
About NextCure, Inc.
NextCure is a biopharmaceutical company focused on managing its legacy clinical and intellectual property assets, pursuing opportunities to maximize those legacy assets, fulfilling ongoing obligations under its existing collaboration and licensing agreements and advancing completion of the Merger with Avere.
Forward-Looking Statements
Some of the statements contained in this press release are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 concerning NextCure, Avere, the Merger and other matters, including with respect to the structure, timing and completion of the Merger; the combined company’s listing on Nasdaq after closing of the Merger; expectations regarding the ownership structure of the combined company; expectations regarding the contingent value rights; the future operations of the combined company; the nature, strategy and focus of the combined company; as well as funding for our operations, our expected cash runway, objectives and expectations for our business, operations and financial performance and condition, and opportunities to monetize, partner, license or otherwise derive value from our legacy assets. Any statements contained herein that are not statements of historical fact may be deemed to be forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as “aim”, “anticipate”, “assume”, “believe”, “continue”, “could”, “should”, “due”, “estimate”, “expect”, “intend”, “hope”, “may”, “objective”, “plan”, “predict”, “project”, “potential”, “positioned”, “seek”, “target”, “towards”, “forward”, “later”, “will”, “would”, and other similar expressions that are predictions of or indicate future events and future trends, or the negative of these terms or similar language.
Forward-looking statements involve substantial risks and uncertainties that could cause actual results to differ materially from those projected in any forward-looking statement. Such risks and uncertainties include, among others: risks associated with the possible failure to satisfy the conditions to the closing or consummation of the Merger, including NextCure’s failure to obtain stockholder approval for the Merger; risks associated with the potential failure to complete the financing transaction in a timely manner or at all; risks associated with the uncertainty as to the timing of the consummation of the Merger and the ability of each of NextCure and Avere to consummate the transactions contemplated by the Merger; risks associated with NextCure’s continued listing on The Nasdaq Stock Market, LLC until closing of the Merger; the failure or delay in obtaining required approvals from any governmental or quasi-governmental entity necessary to consummate the Merger; the occurrence of any event, change or other circumstance or condition that could give rise to the termination of the Merger prior to the closing or consummation of the Merger; risks associated with the possible failure to realize certain anticipated benefits of the Merger, including with respect to future financial and operating results; the effect of the completion of the Merger on the combined company’s business relationships, operating results and business generally; risks associated with the combined company’s ability to manage expenses and unanticipated spending and costs that could reduce the combined company’s cash resources; risks related to the combined company’s ability to correctly estimate its operating expenses and other events; changes in capital resource requirements; risks related to the inability of the combined company to obtain sufficient additional capital to continue to advance its product candidates or its preclinical programs; the outcome of any legal proceedings that may be instituted against the combined company or any of its directors or officers related to the Merger or the transactions contemplated thereby; the ability of the combined company to obtain, maintain and protect its intellectual property rights, in particular those related to its product candidates; the combined company’s ability to advance the development of its product candidates or preclinical activities under the timelines it anticipates in planned and future clinical trials; the combined company’s ability to replicate in later clinical trials positive results found in preclinical studies and clinical trials of its product candidates; the combined company’s ability to realize the anticipated benefits of its research and development programs, strategic partnerships, licensing programs or other collaborations; regulatory requirements or developments and the combined company’s ability to obtain necessary approvals from the U.S. Food and Drug Administration or other regulatory authorities; changes to clinical trial designs and regulatory pathways; competitive responses to the Merger and changes in expected or existing competition; unexpected costs, charges or expenses resulting from the Merger; potential adverse reactions or changes to business relationships resulting from the completion of the Merger; legislative, regulatory, political and economic developments; risks regarding our ability to monetize, partner, license or otherwise realize value from our legacy development programs and assets and other intellectual property; our expenses, future revenues, capital requirements, needs for or ability to obtain additional financing and the period over which our current cash and cash equivalents will be sufficient to fund our operations; market and other conditions; the timing and success of strategic transactions involving our legacy programs and our ability to receive future milestone, royalty or other contingent payments under our existing collaboration and licensing arrangements; the potential benefits of and our ability to maintain our relationship with LigaChem, Simcere Zaiming Pharmaceutical Co., Ltd. (formerly known as Hainan Simcere Zaiming Pharmaceutical Co., Ltd.), and other third-party vendors and collaborators; our ability to retain key personnel; changes in international relations, tariffs, and other trade regulations between the U.S. and China; developments and projections relating to our competitors and our industry, including competing therapies; and the impact of current and future laws and regulations.
More detailed information on these and additional factors that could affect NextCure’s actual results are described under the heading “Risk Factors” in NextCure’s most recent Annual Report on Form 10-K, its subsequent Quarterly Reports on Form 10-Q and in NextCure’s other filings with the SEC. You should not place undue reliance on any forward-looking statements. Forward-looking statements speak only as of the date of this press release, and NextCure assumes no obligation to update any forward-looking statements, even if expectations change.
No Offer or Solicitation
This communication is not intended to and does not constitute an offer to sell or the solicitation of an offer to subscribe for or buy, or a solicitation of any vote, consent or approval in any jurisdiction in connection with the Merger or otherwise, nor shall there be any sale, issuance or transfer of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended, or an exemption therefrom.
Important Additional Information About the Merger Will Be Filed with the SEC
In connection with the proposed Merger, NextCure filed with the SEC a registration statement on Form S-4 containing a proxy statement/prospectus relating to the proposed Merger. On November 6, 2026, the registration statement on Form S-4 was declared effective by the SEC, and NextCure commenced distribution of the definitive proxy statement/prospectus to its stockholders. NextCure and Avere may also file other documents with the SEC regarding the proposed Merger. This communication is not a substitute for the registration statement, the proxy statement/prospectus or any other document that NextCure may file with the SEC in connection with the Merger.
INVESTORS AND SECURITY HOLDERS ARE URGED TO READ THE REGISTRATION STATEMENT, THE PROXY STATEMENT/PROSPECTUS AND ANY OTHER RELEVANT DOCUMENTS THAT ARE FILED OR WILL BE FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS TO THESE DOCUMENTS, CAREFULLY AND IN THEIR ENTIRETY WHEN THEY BECOME AVAILABLE BECAUSE THEY CONTAIN OR WILL CONTAIN IMPORTANT INFORMATION ABOUT NEXTCURE, AVERE, THE MERGER AND RELATED MATTERS.
Investors and security holders may obtain free copies of the registration statement, the proxy statement/prospectus and other documents filed with the SEC by NextCure through the website maintained by the SEC at www.sec.gov or from NextCure's website at www.nextcure.com under the “Investors” section.
Participants in the Solicitation
NextCure, Avere and their respective directors and executive officers may be deemed to be participants in the solicitation of proxies from NextCure's stockholders in respect of the Merger. Information regarding the directors and executive officers of NextCure is contained in NextCure's Annual Report on Form 10-K for the fiscal year ended December 31, 2025, filed with the SEC, and in subsequent filings made by NextCure with the SEC. Additional information regarding the persons who may, under the rules of the SEC, be deemed participants in the solicitation of proxies in connection with the Merger, and a description of their direct and indirect interests in the Merger, by security holdings or otherwise, will be included in the proxy statement/prospectus and other relevant materials to be filed with the SEC when they become available. These documents may be obtained free of charge from the sources indicated above.
| NextCure, Inc. | |||||||||||||||
| Selected Financial Information | |||||||||||||||
| Selected Statement of Operations Items: | Three Months Ended | Nine Months Ended | |||||||||||||
| September 30, | September 30, | ||||||||||||||
| (in thousands, except share and per share amounts) | 2026 | 2025 | 2026 | 2025 | |||||||||||
| Operating expenses: | |||||||||||||||
| Research and development | $ | 4,535 | $ | 6,136 | $ | 18,794 | $ | 38,123 | |||||||
| General and administrative | 4,428 | 2,809 | 10,291 | 9,736 | |||||||||||
| Restructuring and asset impairment charges, net | (2,044 | ) | - | 3,033 | - | ||||||||||
| Loss from operations | (6,919 | ) | (8,945 | ) | (32,118 | ) | (47,859 | ) | |||||||
| Other income, net | 73 | 321 | 584 | 1,451 | |||||||||||
| Net loss | $ | (6,846 | ) | $ | (8,624 | ) | $ | (31,534 | ) | $ | (46,408 | ) | |||
| Net loss per common share - basic and diluted | $ | (1.29 | ) | $ | (3.22 | ) | $ | (5.97 | ) | $ | (18.84 | ) | |||
| Weighted-average shares outstanding - basic and diluted | 5,309,754 | 2,676,116 | 5,286,453 | 2,462,821 | |||||||||||
| Selected Balance Sheet Items: | |||||||||||||||
| September 30, | December 31, | ||||||||||||||
| (in thousands) | 2026 | 2025 | |||||||||||||
| Cash, cash equivalents, and marketable securities | $ | 8,728 | $ | 41,818 | |||||||||||
| Total assets | $ | 9,700 | $ | 50,183 | |||||||||||
| Accounts payable and accrued liabilities | $ | 4,197 | $ | 10,566 | |||||||||||
| Total stockholders' equity | $ | 5,503 | $ | 34,943 | |||||||||||
Investor Inquiries
Timothy Mayer, Ph.D.
NextCure, Inc.
Chief Operating Officer
(240) 762-6486
IR@nextcure.com
Mike Moyer
Managing Director,
LifeSci Advisors, LLC
Phone: (617) 308-4306
mmoyer@lifesciadvisors.com
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
How much financing supports NextCure’s proposed merger with Avere?
The proposed merger is supported by approximately $820 million of committed financing. This comprises a $320 million concurrent private placement and an additional $500 million placement, of which approximately $266 million will be satisfied through contribution and cancellation of Avere’s outstanding convertible notes.
What were NextCure’s third-quarter 2026 financial results?
NextCure reported a $6.846 million net loss, or $1.29 per share, for the quarter ended September 30, 2026. That compares with a net loss of $8.624 million, or $3.22 per share, a year earlier.
Who can vote at NextCure’s merger meeting, and where are the proxy materials?
NextCure established November 3, 2026 as the record date for its December 9, 2026 special stockholder meeting at 9:00 a.m. Eastern Time. Definitive proxy materials are available free through www.sec.gov or the Investors section of www.nextcure.com.
What will NextCure be called after the Avere merger?
Assuming completion of the merger, the combined company is expected to operate as Avere and trade on the Nasdaq Global Select Market under the ticker AVRX.
What is the status of NextCure’s SIM0505 clinical study?
NextCure completed treatment and transition activities for patients enrolled in the SIM0505 clinical study by August 31, 2026. The company continues to evaluate opportunities to partner, license or otherwise monetize rights associated with the program.