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NextCure to Present Phase 1b Data of NC410 in Combination with Pembrolizumab at ASCO 2024

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NextCure, Inc. (NXTC) will present Phase 1b data of NC410 in combination with pembrolizumab at ASCO 2024. The clinical trial investigator will showcase results from a study on immune checkpoint inhibitors in colorectal and ovarian cancer patients.
NextCure, Inc. (NXTC) presenterà i dati della Fase 1b di NC410 in combinazione con pembrolizumab all'ASCO 2024. L'investigatore del trial clinico esporrà i risultati di uno studio sugli inibitori dei checkpoint immunitari in pazienti affetti da cancro al colon-retto e ovarico.
NextCure, Inc. (NXTC) presentará los datos de la Fase 1b de NC410 en combinación con pembrolizumab en el ASCO 2024. El investigador del ensayo clínico mostrará los resultados de un estudio sobre inhibidores de puntos de control inmunológicos en pacientes de cáncer colorrectal y de ovario.
NextCure, Inc. (NXTC)는 2024년 ASCO에서 NC410과 pembrolizumab를 결합한 1b상 데이터를 발표할 예정입니다. 임상 시험 연구자는 대장암과 난소암 환자를 대상으로 한 면역 체크포인트 억제제에 관한 연구 결과를 공개할 것입니다.
NextCure, Inc. (NXTC) présentera les données de la phase 1b de NC410 en combinaison avec le pembrolizumab lors de l'ASCO 2024. L'investigateur de l'essai clinique présentera les résultats d'une étude sur les inhibiteurs de points de contrôle immunitaire chez des patients atteints de cancer colorectal et ovarien.
NextCure, Inc. (NXTC) wird auf der ASCO 2024 Daten der Phase 1b von NC410 in Kombination mit Pembrolizumab präsentieren. Der klinische Studienleiter wird Ergebnisse aus einer Studie zu Immuncheckpoint-Inhibitoren bei Patienten mit Kolorektal- und Eierstockkrebs vorstellen.
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BELTSVILLE, Md., April 24, 2024 (GLOBE NEWSWIRE) --  NextCure, Inc. (Nasdaq: NXTC), a clinical-stage biopharmaceutical company committed to discovering and developing novel, first-in-class and best-in-class therapies to treat cancer, today announced that clinical trial investigator Eric S. Christenson, M.D., Assistant Professor of Oncology at Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, will present a poster on clinical data from the Phase 1b portion of a study evaluating NC410 in combination with pembrolizumab at the American Society of Clinical Oncology (ASCO) Annual Meeting from May 31 – June 4 in Chicago.

Presentation details:

Title: A phase 1b study of NC410 in combination with pembrolizumab in immune checkpoint inhibitor (ICI) naïve, and refractory microsatellite stable (MSS)/microsatellite instability-low (MSI-L) colorectal cancer (CRC) and ovarian cancer
Date and Time: June 1, 2024, 9:00 am-12:00 pm CT
Session: Poster Session: Developmental Therapeutics—Immunotherapy
Abstract Number: 2538

About NextCure, Inc.

NextCure is a clinical-stage biopharmaceutical company that is focused on advancing innovative medicines that treat cancer patients that do not respond to, or have disease progression on, current therapies, through the use of differentiated mechanisms of actions including antibody-drug conjugates, antibodies and proteins. We focus on advancing therapies that leverage our core strengths in understanding biological pathways and biomarkers, the interactions of cells, including in the tumor microenvironment, and the role each interaction plays in a biologic response. www.nextcure.com

Cautionary Statement Regarding Forward-Looking Statements

Statements made in this press release that are not historical facts are forward-looking statements. Words such as “expects,” “believes,” “intends,” “hope,” “forward” and similar expressions are intended to identify forward-looking statements. Examples of forward-looking statements in this press release include, among others, statements about NextCure’s plans, objectives, and intentions with respect to the discovery of immunomedicine targets and the discovery and development of immunomedicines. Forward-looking statements involve substantial risks and uncertainties that could cause actual results to differ materially from those projected in any forward-looking statement. Such risks and uncertainties include, among others: our limited operating history and no products approved for commercial sale; our history of significant losses; our need to obtain additional financing; risks related to clinical development, including that early clinical data may not be confirmed by later clinical results; risks that pre-clinical research may not be confirmed in clinical trials; risks related to marketing approval and commercialization; and the unproven approach to the discovery and development of product candidates based on our FIND-IO platform. More detailed information on these and additional factors that could affect NextCure’s actual results are described in NextCure’s filings with the Securities and Exchange Commission (the “SEC”), including NextCure’s most recent Form 10-K and subsequent Form 10-Q. You should not place undue reliance on any forward-looking statements. NextCure assumes no obligation to update any forward-looking statements, even if expectations change.



FAQ

What is NextCure (NXTC) presenting at ASCO 2024?

NextCure will present Phase 1b data of NC410 in combination with pembrolizumab at ASCO 2024.

Who is the clinical trial investigator presenting the data at ASCO 2024?

Eric S. Christenson, M.D., Assistant Professor of Oncology at Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, will present the data.

What type of cancer is the study focusing on?

The study is evaluating NC410 in combination with pembrolizumab in immune checkpoint inhibitor naïve and refractory colorectal and ovarian cancer patients.

When will the presentation take place at ASCO 2024?

The presentation is scheduled for June 1, 2024, from 9:00 am to 12:00 pm CT.

What is the abstract number of the presentation?

The abstract number is 2538.

NextCure, Inc.

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About NXTC

nextcure, inc., a clinical-stage biopharmaceutical company, engages in discovering and developing novel immunomedicines to treat cancer and other immune-related diseases by restoring normal immune function. its lead product candidate is nc318, which is in phase 2 clinical trials for the treatment of advanced or metastatic solid tumors. the company is also developing nc410, is a novel immunomedicine designed to block immune suppression mediated by an immune modulator called leukocyte-associated immunoglobulin-like receptor 1. its discovery and research programs include an antibody in preclinical evaluation of other potential novel immunomodulatory molecules that targets a novel member of the b7-family of immunomodulatory proteins; and an antibody in preclinical development targeting an immune modulator that is expressed in inflamed tissue and the tumor microenvironment in various tumor types. nextcure, inc. has a license agreement with yale university; and a research and development col