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OptimizeRx Launches CopayCue™, a Next-Generation Copay Activation Solution Powered by Real-Time Prescribing Intent

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(Moderate)
Rhea-AI Sentiment
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OptimizeRx (Nasdaq: OPRX) launched CopayCue, a copay activation solution that uses real-time HCP prescribing intent to deliver brand savings offers directly within e-prescribing workflows.

Powered by data from 400+ EHR/e-prescribing platforms, it can engage 900K authenticated HCPs and has shown prescription lift of 4–5% over EHR banners and 11.5% in standalone programs.

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AI-generated analysis. Not financial advice.

Positive

  • Launch of CopayCue, a next-generation copay activation solution integrated into prescribing workflows
  • Access to real-time intent data from more than 400 EHR and e-prescribing platforms
  • Capability to engage 900,000 authenticated healthcare professionals at prescribing moments
  • Reported 4–5% prescription lift over EHR banners when using CopayCue
  • Standalone affordability programs cited with an average 11.5% prescription lift

Negative

  • None.

Key Figures

Medication cost-related non-adherence: 43% of U.S. adults Unfilled new-drug prescriptions: Nearly two thirds Non-adherence cost: $100–$300 billion annually +4 more
7 metrics
Medication cost-related non-adherence 43% of U.S. adults Reported not taking medication as prescribed due to cost
Unfilled new-drug prescriptions Nearly two thirds Portion of prescriptions for newly launched drugs unfilled in first year
Non-adherence cost $100–$300 billion annually Estimated cost to the U.S. health system of medication non‑adherence
EHR and e‑prescribing platforms More than 400 platforms Size of OptimizeRx’s proprietary network feeding real‑time intent data
Authenticated HCPs reachable 900K HCPs Engaged at critical prescribing moments via CopayCue
Incremental prescription lift 4–5% Increase over EHR banners alone from CopayCue activation
Standalone program prescription lift 11.5% Average prescription lift for standalone affordability programs cited

Peers on Argus

OPRX was up while at least two close peers, NRC and DH, also traded higher, sugg...
1 Up 1 Down

OPRX was up while at least two close peers, NRC and DH, also traded higher, suggesting a broader sector bid even as others like SPOK and TBRG declined.

Historical Context

5 past events · Latest: Jun 25 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Jun 25 Product launch Positive +3.4% Launch of Natural Language Audience Builder for life sciences media planning.
Jun 1 Investor conferences Neutral +3.7% Management participation in two June 2026 investor conferences.
May 21 Partnership news Positive -0.6% DeepIntent becomes first healthcare DSP to integrate OPRX authenticated EHR network.
May 12 Earnings update Neutral -22.5% Q1 2026 results and updated 2026 guidance, including revenue and EBITDA targets.
May 11 Platform launch Positive -3.6% Launch of programmatic access to authenticated EHR advertising at scale.
Pattern Detected

Recent OPRX news has produced mixed reactions, with some product launches selling off while other updates and conferences were met with gains.

Regulatory & Risk Context

Short Interest: 11.44%
Short Interest
11.44% of float
0% 15% 30%+
moderate as of 2026-06-15 Days to cover: 6.33

Short interest appears elevated, indicating potential for sharper volatility if positioning shifts or liquidity changes.

Market Pulse Summary

This announcement extends OPRX’s EHR-based solutions with CopayCue, targeting affordability barriers...
Analysis

This announcement extends OPRX’s EHR-based solutions with CopayCue, targeting affordability barriers that affect 43% of adults and driving reported prescription lifts up to 11.5%. Investors may watch adoption across the 400+-platform network and competitive responses.

Key Terms

e-prescribing, electronic health record (ehr), hcp, point of care
4 terms
e-prescribing technical
"directly within the e-prescribing workflow, when HCP intent is highest"
E-prescribing is the electronic transmission of a medical prescription from a healthcare professional to a pharmacy using digital systems rather than paper or fax. Think of it like sending a secure, digital grocery list that goes straight to the store: it speeds up fulfillment, reduces mistakes, and creates data that can be tracked. For investors, adoption and quality of e-prescribing systems can affect healthcare costs, pharmacy sales, regulatory compliance, and the competitive position of health IT and pharmacy businesses.
electronic health record (ehr) technical
"network of more than 400 electronic health record (EHR) and e-prescribing platforms"
A digital system that stores a patient’s medical history, test results, medications and treatment notes in one place so healthcare providers can view and update records electronically. For investors, EHRs matter because they drive how healthcare is delivered, influence costs, create recurring revenue for software providers, and carry regulatory and cybersecurity risks; think of an EHR as the digital filing cabinet or smartphone app that organizes a clinic’s entire patient chart.
hcp medical
"reach and engage healthcare professionals (HCPs) and patients at the most important decision points"
An HCP (healthcare professional) is a licensed medical practitioner—such as a doctor, nurse, pharmacist or clinician—who diagnoses, treats and advises patients. For investors, HCPs are important because their prescribing choices and treatment recommendations directly affect product sales and market uptake, acting like gatekeepers whose preferences and acceptance can determine a therapy’s commercial success and regulatory exposure.
point of care medical
"expand patient access to therapy through point of care engagement"
Point of care is the place and moment where a patient receives medical attention or testing — for example, a doctor's office, clinic, bedside, or urgent care — rather than a distant laboratory. For investors, point‑of‑care products matter because they speed diagnosis and treatment, lower costs, and can increase demand for portable tests and devices in many healthcare settings, much like having a home thermometer instead of sending samples away.

AI-generated analysis. Not financial advice.

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Enhanced technology delivers brand savings offers directly within the prescribing workflow, when HCP intent is highest

WALTHAM, Mass., June 30, 2026 (GLOBE NEWSWIRE) -- OptimizeRx Corp. (the “Company”) (Nasdaq: OPRX), a leading provider of healthcare technology solutions helping life sciences companies reach and engage healthcare professionals (HCPs) and patients at the most important decision points, today announced the launch of CopayCue™, designed to make brand savings offers more transparent for physicians at the point of prescribing.

CopayCue is a next-generation enhancement to OptimizeRx’s foundational Financial Assistance solution, using verified, real-time HCP prescribing intent data to deliver brand savings information, such as copay cards and affordability resources, directly within the e-prescribing workflow.

Overcoming the Affordability Barrier with Real-Time Intent Data

Medication affordability impacts both HCP prescribing decisions and patient access to therapy, with 43% of U.S. adults reporting they have not taken their medication as prescribed due to cost. And for newly launched drugs, nearly two thirds of prescriptions go unfilled in their first year on the market. The cost to the U.S. health system of non-adherence has been estimated at $100-$300 billion annually.

Life sciences organizations invest heavily in brand awareness marketing and financial support programs only to lose patients when they go to fill prescriptions at the pharmacy. When savings information is connected to the prescribing workflow, it can increase brand sentiment and conversion, drive program utilization, and ensure patients have access to the intended therapies as prescribed by their physicians.

Using real-time data signals from OptimizeRx's proprietary, best-in-class network of more than 400 electronic health record (EHR) and e-prescribing platforms, CopayCue activates brand savings offers at the precise moment an HCP demonstrates intent to prescribe a specific therapy. It enables life sciences organizations to:

  • Increase the transparency of savings offers within the e-prescribing workflow
  • Remove out-of-pocket cost uncertainty as a barrier to script writing
  • Engage 900K authenticated HCPs at critical prescribing moments
  • Automatically send the savings offer directly to the pharmacy, appended to the prescription

OptimizeRx data demonstrates the impact of affordability engagement within clinical workflows. CopayCue has been shown to increase prescription lift by 4-5% over EHR banners alone, and standalone programs have achieved an average prescription lift of 11.5%.

“CopayCue brings together two powerful signals: a physician’s real-time intent to prescribe and a brand’s ability to deliver savings support at that exact moment,” said Louis Trivento, OptimizeRx SVP Strategic Partnerships. “For life sciences brands, this creates a more precise way to activate savings offers inside the prescribing workflow—helping improve provider relevance, strengthen campaign performance, and reduce missed opportunities at the point of conversion.”

“The launch of CopayCue builds on OptimizeRx's broader commitment to improve the impact of life sciences marketing and to expand patient access to therapy through point of care engagement,” said Stephen Silvestro, OptimizeRx CEO. “By now linking copay delivery directly to prescriber intent, we’re better able to tackle the billion-dollar affordability challenge, and help clients deliver timely, relevant financial assistance within the clinical workflows HCPs use every day.”

About OptimizeRx

OptimizeRx is a leading healthcare technology company that’s redefining how life science brands connect with patients and healthcare providers. Our platform combines innovative AI-driven tools like the Dynamic Audience Activation Platform (DAAP) and Micro-Neighborhood Targeting (MNT) to deliver timely, relevant, and hyper-local engagement. By bridging the gap between HCP and DTC strategies, we empower brands to create synchronized marketing solutions that drive faster treatment decisions and improved patient outcomes.

Our commitment to privacy-safe, patient-centric technology ensures that every interaction is designed to make a meaningful impact, delivering life-changing therapies to the right patients at the right time. Headquartered in Waltham, Massachusetts, OptimizeRx partners with some of the world’s leading pharmaceutical and life sciences companies to transform the healthcare landscape and create a healthier future for all.

For more information, follow the Company on LinkedIn or X, or visit www.optimizerx.com.  

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "can", "drive”, “ensure”, "activates", "enables", "increase", "engage", "creates”, “help” or other similar words and expressions are intended to identify these forward-looking statements. All statements in this press release that reflect the Company's expectations, assumptions, projections, beliefs or opinions about the future, other than statements of historical fact, are forward-looking statements, including, without limitation, statements relating to the ability of the financial savings information to increase brand sentiment and conversion, to drive program utilization, and to ensure patients have access to the intended therapies as prescribed by their physicians, the ability of the Company to deliver brand savings information directly within the e-prescribing workflow based on HCP intent, to activate brand savings offers at the precise moment an HCP demonstrates intent to prescribe a specific therapy, to help improve provider relevance, strengthen campaign performance, and reduce missed opportunities at the point of conversion, and the ability of the Company to enable life sciences companies and healthcare marketers to increase savings offer transparency, overcome cost as a prescribing barrier, to deliver timely, relevant financial assistance information within the clinical workflows, and to increase prescription volumes. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements are based upon the Company’s current expectations and involve assumptions regarding the Company's business, the economy, and other future conditions that may never materialize or may prove to be incorrect. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted, or quantified. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties including, but not limited to the effect of government regulation, seasonal trends, dependence on a concentrated group of customers, cybersecurity incidents that could disrupt operations, the ability to keep pace with growing and evolving technology, the ability to maintain contracts with eRx platforms and EHR networks, competition, and other factors discussed in the Company’s Annual Report on Form 10-K for the year ended December 31, 2025, and in other filings the Company has made and may make with the SEC in the future. One should not place undue reliance on these forward-looking statements, which speak only as of the date on which they were made. The Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as may be required by law.

OptimizeRx Contact
Jennifer Dinkel, SVP Marketing
jdinkel@optimizerx.com

Investor Relations Contact
Douglas Farrell
LifeSci Advisors, LLC
dfarrell@lifesciadvisors.com

Press Inquiries
Matter Communications
optimizerx@matternow.com


FAQ

What is CopayCue from OptimizeRx (Nasdaq: OPRX) launched on June 30, 2026?

CopayCue is a copay activation solution that delivers brand savings offers within the e-prescribing workflow. According to OptimizeRx, it links real-time HCP prescribing intent with copay cards and affordability resources at the point of care to support therapy access.

How does CopayCue use real-time prescribing intent data for OPRX clients?

CopayCue uses real-time data signals indicating a physician’s intent to prescribe a specific therapy to trigger savings offers. According to OptimizeRx, this activation occurs inside the e-prescribing workflow at the moment of intent, helping reduce out-of-pocket cost uncertainty and missed conversions.

How many healthcare professionals can OptimizeRx CopayCue reach within its network?

CopayCue can engage 900,000 authenticated healthcare professionals within prescribing workflows. According to OptimizeRx, it leverages a proprietary network of more than 400 EHR and e-prescribing platforms to present savings information when providers are actively writing prescriptions.

What prescription lift has CopayCue demonstrated for life sciences brands using OPRX solutions?

CopayCue has been shown to increase prescription lift by 4–5% over EHR banners alone. According to OptimizeRx, standalone affordability engagement programs enabled by its technology have achieved an average prescription lift of 11.5% within clinical workflows.

How does CopayCue aim to address medication affordability and non-adherence?

CopayCue connects savings offers directly to prescribing decisions to reduce cost barriers for patients. According to OptimizeRx, affordability issues contribute to widespread non-adherence, and timely copay support can improve program utilization, brand conversion, and access to intended therapies.

What specific actions can life sciences companies take with OptimizeRx CopayCue?

Life sciences companies can use CopayCue to increase visibility of savings offers and send copay information directly to pharmacies. According to OptimizeRx, the platform also helps remove out-of-pocket cost uncertainty and strengthens campaign performance at critical prescribing moments.