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OptimizeRx Reports Strong Fourth Quarter and Full Year 2025 Financial Results

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OptimizeRx (Nasdaq: OPRX) reported strong Q4 and full-year 2025 results with Q4 revenue $32.2M, full-year revenue $109.4M (19% YoY), and record Q4 net income $5.0M and Q4 adjusted EBITDA $12.0M. The board authorized a $10M share repurchase program and 2026 guidance was set to $109M–$114M revenue and $21M–$25M adjusted EBITDA.

Cash was $23.4M at year-end, operating cash flow improved, and the company reduced term loan principal by $2M.

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Positive

  • Full-year revenue of $109.4M, up 19% year-over-year
  • Q4 adjusted EBITDA record of $12.0M, boosting profitability
  • Full-year adjusted EBITDA of $24.3M, implying >20% margin
  • Board-authorized $10M share repurchase program effective March 12, 2026
  • Year-end cash of $23.4M and $18.7M net operating cash provided

Negative

  • Q4 revenue flat at $32.2M versus $32.3M year-ago, showing limited near-term top-line growth
  • Net revenue retention declined to 116% from 121%, indicating reduced existing-client growth
  • Average revenue per top-20 pharma fell to $2,838 from $2,976, a potential concentration pressure

Market Reaction – OPRX

+5.58% $7.95 2.2x vol
15m delay 14 alerts
+5.58% Since News
+31.1% Peak in 3 min
$7.95 Last Price
$7.30 $8.01 Day Range
+$7M Valuation Impact
$140M Market Cap
2.2x Rel. Volume

Following this news, OPRX has gained 5.58%, reflecting a notable positive market reaction. Argus tracked a peak move of +31.1% during the session. Our momentum scanner has triggered 14 alerts so far, indicating notable trading interest and price volatility. The stock is currently trading at $7.95. This price movement has added approximately $7M to the company's valuation. Trading volume is elevated at 2.2x the average, suggesting notable buying interest.

Data tracked by StockTitan Argus (15 min delayed). Upgrade to Silver for real-time data.

Key Figures

Q4 2025 revenue: $32.2 million Q4 2025 gross profit: $24.1 million Q4 2025 GAAP net income: $5.0 million +5 more
8 metrics
Q4 2025 revenue $32.2 million Fourth quarter 2025 revenue versus $32.3 million in Q4 2024
Q4 2025 gross profit $24.1 million Fourth quarter 2025, up 9% year-over-year
Q4 2025 GAAP net income $5.0 million Fourth quarter 2025 vs $(0.1) million loss in Q4 2024
2025 revenue $109.4 million Full year 2025 revenue, up from $92.1 million in 2024
2025 GAAP net income $5.1 million Full year 2025 vs $(20.1) million net loss in 2024
2025 adjusted EBITDA $24.3 million Full year 2025 vs $11.7 million in 2024
Cash and cash equivalents $23.4 million Balance at December 31, 2025 vs $13.4 million a year earlier
Share repurchase authorization $10 million Board-authorized share repurchase program effective March 12, 2026

Market Reality Check

Price: $7.87 Vol: Volume 294,806 is below t...
low vol
$7.87 Last Close
Volume Volume 294,806 is below the 438,482 20-day average ahead of the earnings release. low
Technical Price $7.87 is trading below the $14.49 200-day moving average and 64.63% under the 52-week high.

Peers on Argus

OPRX gained 7.51% while peers were mixed: DH rose 7.46%, SPOK and SY were modest...

OPRX gained 7.51% while peers were mixed: DH rose 7.46%, SPOK and SY were modestly positive, and TBRG and NRC declined, indicating a stock-specific reaction rather than a sector-wide move.

Previous Earnings Reports

5 past events · Latest: Nov 06 (Positive)
Same Type Pattern 5 events
Date Event Sentiment Move Catalyst
Nov 06 Q3 2025 earnings Positive -17.4% Reported Q3 2025 growth, improved profitability, and raised 2025–2026 guidance ranges.
Oct 30 Earnings call scheduling Neutral +4.5% Announced upcoming Q2 2025 results call with full dial-in and webcast details.
Aug 07 Q2 2025 earnings Positive +34.7% Strong Q2 2025 revenue, return to GAAP profitability, and higher full-year guidance.
May 12 Q1 2025 earnings Positive +19.7% Q1 2025 growth, improved losses, and increased 2025 revenue and EBITDA guidance.
Mar 12 Q4 2024 earnings Positive +51.7% Strong Q4 and 2024 results with DAAP expansion and initial 2025 guidance.
Pattern Detected

Earnings-related headlines have usually led to positive price reactions, with one notable selloff on strong Q3 2025 results.

Recent Company History

Over the last year, OPRX’s earnings cadence has shown steady revenue growth and improving profitability. Q1–Q3 2025 reports highlighted rising revenue, expanding gross profit, and a shift from GAAP losses to income, often accompanied by raised guidance. The strong Q4 and full-year 2025 results with record revenue and adjusted EBITDA extend this trajectory. Historically, most earnings updates (e.g., on Mar 12, May 12, and Aug 7, 2025) saw shares move higher, with the Q3 2025 selloff an exception.

Historical Comparison

+18.6% avg move · Across five recent earnings-related releases, OPRX moved an average of 18.64%. Today’s 7.51% gain is...
earnings
+18.6%
Average Historical Move earnings

Across five recent earnings-related releases, OPRX moved an average of 18.64%. Today’s 7.51% gain is positive but more moderate than prior earnings reactions.

Earnings releases through 2025 showed a steady progression: Q1 and Q2 established double-digit growth and improving margins, Q3 maintained profitability and higher guidance, and Q4/full-year 2025 confirmed record revenue and adjusted EBITDA.

Market Pulse Summary

The stock is up +5.6% following this news. A strong positive reaction aligns with the company’s reco...
Analysis

The stock is up +5.6% following this news. A strong positive reaction aligns with the company’s record Q4 and full-year 2025 results and the announced $10 million buyback. The 7.51% gain is smaller than the average 18.64% move seen after past earnings headlines, but still fits a pattern where most earnings updates have been rewarded. With shares trading well below the $14.49 200-day MA, prior sharp post-earnings swings highlight that volatility around results has been common.

Key Terms

adjusted EBITDA, non-GAAP, GAAP, net revenue retention, +2 more
6 terms
adjusted EBITDA financial
"Q4 net income and adjusted EBITDA hit records at $5.0 million and $12.0 million"
Adjusted EBITDA is a way companies measure how much money they make from their core operations, like running a business, by removing certain costs or income that aren’t part of regular business activities. It helps investors see how well a company is doing without distractions from unusual expenses or gains, making it easier to compare companies or track performance over time.
non-GAAP financial
"Non-GAAP net income in the fourth quarter of 2025 totaled $9.9 million"
Non-GAAP refers to financial measures that companies use to show their earnings or performance without including certain expenses or income that are often added back to give a different picture. It matters because it can make a company's results look better or more favorable, but it may also hide important costs, so investors need to look at both GAAP (official rules) and non-GAAP numbers to get a full understanding.
GAAP financial
"GAAP net income in the fourth quarter of 2025 totaled $5.0 million"
GAAP, or Generally Accepted Accounting Principles, are a set of standardized rules and guidelines that companies follow when preparing their financial statements. They ensure consistency, transparency, and comparability across different companies, making it easier for investors to understand and compare financial information accurately. This helps investors make informed decisions based on trustworthy and uniform financial reports.
net revenue retention financial
"Net revenue retention | | 116 | % | | 121 | %"
Net revenue retention measures how much revenue a company keeps from its existing customers over a set period after accounting for customers who leave, reductions in spending, and any increases from upsells or cross-sells. For investors it shows whether a company can grow sales from the customers it already has—like checking whether a store is making more or less money from its regular shoppers—which signals business health and future revenue durability.
restricted stock units financial
"4,000 restricted stock units converted into 4,000 shares of common stock"
Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.
Rule of 40 financial
"we set a goal to become a Rule of 40 company and we have, in 2025"
The "rule of 40" is a simple guideline used by investors to assess the health of a company's growth and profitability. It adds a company's growth rate to its profit margin; if the total is 40% or higher, the company is generally considered to be performing well. This helps investors quickly gauge whether a company is balancing rapid growth with solid profits, much like checking if a car’s speed and fuel efficiency together are within a safe and efficient range.

AI-generated analysis. Not financial advice.

-   Q4 revenue of $32.2 million
-   Q4 gross profit increased 9% year-over-year to $24.1 million
-   Q4 net income and adjusted EBITDA hit records at $5.0 million and $12.0 million, respectively
-   Updating 2026 revenue guidance to $109-$114 million and adjusted EBITDA guidance to $21-$25 million
-   Paid off an incremental $2 million in principal from term loan during Q4
-   OptimizeRx's Board authorizes a $10 million share repurchase program
 

WALTHAM, Mass., March 05, 2026 (GLOBE NEWSWIRE) -- OptimizeRx Corp. (the “Company”) (Nasdaq: OPRX), a leading provider of healthcare technology solutions helping life sciences companies reach and engage healthcare professionals (HCPs) and patients, today announced results for the fourth quarter and full year ended December 31, 2025.

Financial Highlights

  • Revenue in the fourth quarter of 2025 remained consistent at $32.2 million when compared to $32.3 million in the same period of 2024. Full year revenue for 2025 came in at $109.4 million, a 19% increase, when compared to $92.1 million in the same year-ago period.
  • Gross profit in the fourth quarter of 2025 increased 9% year-over-year to $24.1 million from $22.0 million in the same period of 2024. Gross profit for the full year of 2025 was $73.6 million an increase from $59.4 million in the same year-ago period.
  • GAAP net income in the fourth quarter of 2025 totaled $5.0 million, or $0.26 per diluted share, compared to net loss of $(0.1) million, or $0.00 per diluted share, in the same period of 2024. GAAP net income for the full year of 2025 totaled $5.1 million, or $0.27 per diluted share, compared to net loss of $(20.1) million, or $(1.10) per diluted share, in the same year-ago period.
  • Non-GAAP net income in the fourth quarter of 2025 totaled $9.9 million, or $0.51 per diluted share, compared to $5.5 million, or $0.30 per diluted share in the same period of 2024. Non-GAAP net income in the full year of 2025 came in at $19.9 million, or $1.05 per diluted share, compared to $6.2 million, or $0.33 per diluted share, in the same year-ago period. (see *Non-GAAP Measures below).
  • Adjusted EBITDA for the fourth quarter of 2025 increased to $12.0 million compared to $8.8 million in the same period of 2024. Adjusted EBITDA for the full year of 2025 came in at $24.3 million compared to $11.7 million in the same year-ago period. (see *Non-GAAP Measures below).
  • Cash and cash equivalents was $23.4 million as of December 31, 2025 as compared to $13.4 million as of December 31, 2024
  • Net cash provided by operating activities was $18.7 million for the year ended December 31, 2025 as compared to $4.9 million in the same period of 2024.

Stephen L. Silvestro, OptimizeRx CEO commented, “We delivered a strong fourth quarter, exceeding both consensus and internal expectations, with revenue of $32.2 million and adjusted EBITDA of $12.0 million. For the full year, revenue reached a record $109.4 million and adjusted EBITDA totaled $24.3 million, reflecting more than 20% margin and nearly $19 million in operating cash flow. Importantly, one year ago, we set a goal to become a Rule of 40 company and we have, in 2025, achieved this benchmark demonstrating the strength of our profitable growth model and the durability of our platform. We continue to be focused on becoming a sustainable Rule of 40 company over the next few years.

“We are beginning to see increased market volatility, driven in part by uncertainty surrounding Most Favored Nation (MFN) pricing. In response, we believe some customers are taking a more measured approach to discretionary spending and contract duration. While this dynamic may create some near-term headwinds, we continue to see solid engagement across our network and remain confident in the underlying demand trends supporting our business.

“Against that backdrop, OptimizeRx continues to play a mission-critical role for life sciences companies by enhancing brand visibility, reducing script abandonment, improving interoperability between disparate point-of-care platforms, and supporting the growing shift toward complex specialty medications. In addition, we believe advancements in AI will enable customers to reallocate marketing dollars from content creation toward reach and execution—areas where we provide differentiated value with significant ROIs, further strengthening our position over time.”

 For the Year Ended
December 31,
 
Key Performance Indicators (KPIs)**2025
 2024
 
 (in thousands, except percentages) 
Average revenue per top 20 pharmaceutical manufacturers$2,838  $2,976  
Percent of total revenue attributable to top 20 pharmaceutical manufacturers 52%  65% 
Net revenue retention 116%  121% 
Revenue per average full-time employee$839  $701  
         

Financial Outlook

The Company is also updating its fiscal year 2026 guidance at this time and is expecting revenue to be between $109 million and $114 million with Adjusted EBITDA to be between $21 million and $25 million.

Share Repurchase Program

OptimizeRx’s board of directors has authorized a share repurchase program for up to $10 million of the Company’s outstanding common stock. Under this new program, share repurchases may be made from time to time depending on market conditions, share price, share availability and other factors at the Company’s discretion. This share repurchase authorization is effective March 12, 2026 and expires on the earlier of March 15, 2027, or when the repurchase of $10 million shares has been reached. The Company’s repurchase of shares will take place in open market transactions or privately negotiated transactions in accordance with applicable securities and other laws, including the Securities Exchange Act of 1934. The Company intends to finance the purchase using its available cash and cash equivalents. The Company’s board of directors may modify, suspend, extend or terminate the share repurchase program at any time.

Conference Call, Webcast, and Webcast Replay Information

Date:Thursday, March 5, 2026
Time:4:30 p.m. Eastern Time (1:30 p.m. Pacific Time)
Toll Free:1-844-825-9789
International:1-412-317-5180
Conference ID10206362
Call Me:https://callme.viavid.com/?$Y2FsbG1lPXRydWUmcGFzc2NvZGU9JmluZm89Y29tcGFueSZyPXRydWUmYj0xNg==
Webcast:https://viavid.webcasts.com/starthere.jsp?ei=1750927&tp_key=099094fd29
Call Me Passcode:6586380
Webcast Replay:The archived webcast will be on the investor relations section of the OptimizeRx website
 

Invitation

In an effort to increase relations with institutional investors, OptimizeRx management has dedicated time to hosting individual meetings with portfolio managers and analysts. If you are interested in scheduling a meeting with OptimizeRx management, please contact: adsilva@optimizerx.com or shalper@lifesciadvisors.com.

*Non-GAAP Measures

In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), this earnings release also contains non-GAAP financial measures. The reasons why we believe these measures provide useful information to investors and, for historical periods, a reconciliation of these measures to the most directly comparable GAAP measures are included in the supplemental tables that follow.

Although the Company provides guidance for Adjusted EBITDA, a non-GAAP financial measure, it is not able to provide guidance to the most directly comparable GAAP measure. Reconciliations for forward-looking figures would require unreasonable effort at this time because of the uncertainty and variability of the nature and amount of certain components of various necessary GAAP components, including, for example, those related to compensation, acquisition expenses, other income, amortization or others that may arise during the year, and the Company’s management believes such reconciliations would imply a degree of precision that would be confusing or misleading to investors. For the same reasons, the Company is unable to address the probable significance of the unavailable information.

**Definition of Key Performance Indicators

Top 20 pharmaceutical manufacturers: We have updated the definition of “top 20 pharmaceutical manufacturers” in our key performance indicators to be based upon Fierce Pharma’s most updated list of “The top 20 pharma companies by 2024 revenue”. We previously used “The top 20 pharma companies by 2023 revenue”. As a result of this change, prior periods have been restated for comparative purposes.

Net revenue retention: Net revenue retention is a comparison of revenue generated from all clients in the previous period to total revenue generated from the same clients in the following year (i.e., excludes new client relationships for the most recent year).

Revenue per average full-time employee: We define revenue per average full-time employee (FTE) as total revenue over the last 12 months (LTM) divided by the average number of employees over the LTM, which is calculated by taking our total number of FTEs at the end of the prior year period by our total FTE headcount at the end of the most recent period.

About OptimizeRx

OptimizeRx is a leading healthcare technology company that’s redefining how life science brands connect with patients and healthcare providers. Our platform combines innovative artificial intelligence (AI)-driven tools like the Dynamic Audience Activation Platform (DAAP) and Micro-Neighborhood Targeting (MNT) to deliver timely, relevant, and hyper-local engagement. By bridging the gap between HCP and DTC strategies, we empower brands to create synchronized marketing solutions that drive faster treatment decisions and improved patient outcomes.

Our commitment to privacy-safe, patient-centric technology ensures that every interaction is designed to make a meaningful impact, delivering life-changing therapies to the right patients at the right time. Headquartered in Waltham, Massachusetts, OptimizeRx partners with some of the world’s leading pharmaceutical and life sciences companies to transform the healthcare landscape and create a healthier future for all.

For more information, follow the Company on X, LinkedIn or visit www.optimizerx.com. 

Important Cautions Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “anticipates”, “believes”, “estimates”, “expects”, “forecasts”, “intends”, “plans”, “projects”, “targets”, “designed”, “could”, “may”, “should”, “will” or other similar words and expressions are intended to identify these forward-looking statements. All statements that reflect the Company’s expectations, assumptions, projections, beliefs or opinions about the future, other than statements of historical fact, are forward-looking statements, including, without limitation, statements relating to the Company’s future performance, expected revenues, expected Adjusted EBITDA, plans to grow shareholder value creation, plans to continue the Company’s growth and transformation, plans to position the Company to become a sustained “Rule of 40” company, increased market volatility, engagement across the Company’s network, improving interoperability between disparate point-of-care platforms, growing shift toward complex specialty medications, advancements in AI, plans to pay down debt at an accelerated rate, momentum extending into 2026, setting the stage for sustained strength in 2026 and beyond, the timing and amount of repurchases of our common stock and other statements relating to future performance, plans, and expectations. These forward-looking statements are based on the Company’s current expectations and involve assumptions regarding the Company’s business, the economy, and other future conditions that may never materialize or may prove to be incorrect. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted, or quantified. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties including, but not limited to, the effect of government regulation, seasonal trends, dependence on a concentrated group of customers, cybersecurity incidents that could disrupt operations, the ability to keep pace with growing and evolving technology, the ability to maintain contracts with electronic prescription platforms and electronic health records networks, competition, and other factors discussed in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, its subsequent Quarterly Reports on Form 10-Q, and in other filings the Company has made and may make with the Securities and Exchange Commission in the future. One should not place undue reliance on these forward-looking statements, which speak only as of the date on which they were made. The Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as may be required by law.

OptimizeRx Contact
Andy D’Silva, Chief Business Officer
adsilva@optimizerx.com

Investor Relations Contact
Steven Halper
LifeSci Advisors, LLC
shalper@lifesciadvisors.com

OPTIMIZERX CORPORATION
CONSOLIDATED BALANCE SHEETS
(in thousands, except share and per share data)
 
 December 31, 
 2025
 2024
 
ASSETS        
Current assets        
Cash and cash equivalents$23,365  $13,380  
Accounts receivable, net of allowance for credit losses of $260 and $335 at December 31,
2025 and 2024, respectively
 37,752   38,212  
Taxes receivable 752     
Prepaid expenses and other 2,846   2,379  
Total current assets 64,715   53,971  
Property and equipment, net 106   150  
Other assets        
Goodwill 70,869   70,869  
Patent rights, net 4,586   5,517  
Technology assets, net 6,870   8,180  
Tradename and customer relationships, net 29,340   31,819  
Operating lease right-of-use assets 404   366  
Security deposits and other assets 28   296  
Total other assets 112,097   117,047  
TOTAL ASSETS$176,918  $171,168  
LIABILITIES AND STOCKHOLDERS’ EQUITY        
Current liabilities        
Current portion of long-term debt$4,255  $2,000  
Accounts payable 1,636   2,156  
Accrued expenses 11,591   8,486  
Revenue share payable 3,086   5,053  
Taxes payable    318  
Current portion of lease liabilities 193   168  
Deferred revenue 503   473  
Total current liabilities 21,264   18,654  
Non-current liabilities        
Long-term debt, net 21,421   30,816  
Lease liabilities, net of current portion 234   209  
Deferred tax liabilities, net 5,705   4,491  
Total liabilities 48,624   54,170  
Commitments and contingencies        
Stockholders’ equity        
Preferred stock, $0.001 par value, 10,000,000 shares authorized, none issued and
outstanding at December 31, 2025 and 2024, respectively
      
Common stock, $0.001 par value, 166,666,667 shares authorized, 20,500,986 and
20,194,697 shares issued at December 31, 2025 and 2024, respectively
 20   20  
Treasury stock, $0.001 par value,1,741,397 shares purchased at December 31, 2025 and
2024
 (2)  (2) 
Additional paid-in-capital 207,512   201,348  
Accumulated deficit (79,236)  (84,368) 
Total stockholders’ equity$128,294  $116,998  
TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY$176,918  $171,168  
 


OPTIMIZERX CORPORATION
CONSOLIDATED STATEMENTS OF OPERATIONS
(in thousands, except share and per share data)
 
 For the Three Months Ended
December 31,
 For the Year Ended
December 31,
 
 2025
 2024
 2025
 2024
 
                 
Net revenue$32,239  $32,317  $109,429  $92,127  
Cost of revenues, exclusive of depreciation and
amortization presented separately below
 8,139   10,293   35,834   32,749  
Gross profit 24,100   22,024   73,595   59,378  
                 
Operating expenses                
Stock-based compensation 1,960   2,937   6,962   11,467  
Impairment charges 368      368   7,489  
Depreciation and amortization 1,078   1,094   4,327   4,329  
Other general and administrative expenses 12,125   14,358   50,245   49,799  
Total operating expenses 15,531   18,389   61,902   73,084  
Income (loss) from operations 8,569   3,635   11,693   (13,706) 
Other income (expense)                
Interest expense (1,241)  (1,563)  (5,294)  (6,160) 
Other income 59   41   198   152  
Interest income 84   96   353   329  
Total other expenses, net (1,098)  (1,426)  (4,743)  (5,679) 
Income (loss) before provision for income taxes 7,471   2,209   6,950   (19,385) 
Income tax expense (2,451)  (2,286)  (1,818)  (725) 
Net income (loss)$5,020  $(77) $5,132  $(20,110) 
Weighted average number of shares outstanding – basic 18,661,212   18,418,519   18,555,343   18,292,935  
Weighted average number of shares outstanding – diluted 19,381,024   18,418,519   18,998,463   18,292,935  
Income (loss) per share – basic$0.27  $  $0.28  $(1.10) 
Income (loss) per share – diluted$0.26  $  $0.27  $(1.10) 
 


OPTIMIZERX CORPORATION
CONSOLIDATED STATEMENTS OF CASH FLOWS
(in thousands)
 
 For the Year Ended
December 31,
 
 2025
 2024
 
OPERATING ACTIVITIES:        
Net income (loss)$5,132  $(20,110) 
Adjustments to reconcile net income (loss) to net cash provided by operating activities:        
Depreciation and amortization 4,327   4,329  
Impairment charges 368   7,489  
Bad debt expense    208  
Stock-based compensation 6,962   11,467  
Amortization of debt issuance costs 1,110   835  
Change in:        
Accounts receivable 460   (2,168) 
Prepaid expenses and other assets (467)  811  
Accounts payable (520)  (72) 
Revenue share payable (1,967)  (453) 
Accrued expenses and other liabilities 3,374   1,053  
Operating lease liabilities 12     
Taxes receivable and payable (1,070)    
Deferred tax liabilities 1,214   1,449  
Deferred loan fees (250)  (250) 
Deferred revenue 30   301  
NET CASH PROVIDED BY OPERATING ACTIVITIES 18,715   4,889  
         
INVESTING ACTIVITIES:        
Purchases of property and equipment (58)  (112) 
Capitalized software development costs 126   (338) 
NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES 68   (450) 
         
FINANCING ACTIVITIES:        
Repayment of long-term debt (8,000)  (4,000) 
Cash paid for employee withholding taxes related to the vesting of restricted stock units (1,150)  (911) 
Proceeds from exercise of stock options, net of cash paid for withholding taxes 352     
NET CASH USED IN FINANCING ACTIVITIES (8,798)  (4,911) 
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS 9,985   (472) 
CASH AND CASH EQUIVALENTS – BEGINNING OF PERIOD 13,380   13,852  
CASH AND CASH EQUIVALENTS – END OF PERIOD$23,365  $13,380  
         
SUPPLEMENTAL CASH FLOW INFORMATION:        
Cash paid for interest$4,184  $6,203  
Cash paid for income taxes$1,760  $161  
 


OPTIMIZERX CORPORATION
RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL MEASURES
(in thousands, except share and per share data, unaudited)
 

This earnings release includes certain financial measures not derived in accordance with generally accepted accounting principles (GAAP). These non-GAAP financial measures are measures of performance not defined by accounting principles generally accepted in the United States and should be considered in addition to, not in lieu of, GAAP reported measures. Additionally, these non-GAAP measures may not be comparable to similarly titled measures reported by other companies. However, management believes that presenting certain non-GAAP financial measures provides additional information to facilitate comparison of the Company's historical operating results and trends in its underlying operating results and provides transparency on how the Company evaluates its business. Management uses these non-GAAP financial measures in making financial, operating and planning decisions and in evaluating the Company's performance. Management believes that financial information excluding certain items that are not considered to reflect the Company’s ongoing operating results, such as those listed below, improves the comparability of year-to-year results. Consequently, management believes that investors may be able to better understand the Company’s operating results excluding these items. Non-GAAP financial measures may reflect adjustments for items such as asset impairment charges, amortization, stock-based compensation, acquisition expenses, severance tied to executive departures and reduction in force initiatives, shareholder activist related fees, CEO search fees, other income, as well as other items that management believes are not related to the Company’s ongoing performance.

 For the Three Months Ended
December 31,
 For the Twelve Months Ended
December 31,
 
 2025
 2024
 2025
 2024
 
Net income (loss)$5,020  $(77) $5,132  $(20,110) 
Deferred income taxes     153   1,215   153  
Depreciation and amortization 1,078   1,094   4,327   4,329  
Stock-based compensation 1,960   2,937   6,962   11,467  
Impairment charges 368      368   7,489  
Severance charges    1,183   275   1,908  
Shareholder activist related fees       451     
CEO search fees       225     
Other income (59)  (40)  (198)  (152) 
Amortization of debt issuance costs 325   288   1,110   835  
Acquisition expense          243  
Non-GAAP net income     5,538   19,867   6,162  
                 
Non-GAAP net income per share                
Diluted$0.51  $0.30  $1.05  $0.33  
Weighted average shares outstanding:                
Diluted 19,381,024   18,464,605   18,998,463   18,583,936  
 


 For the Three Months Ended
December 31,
 For the Twelve Months Ended
December 31,
 
 2025
 2024
 2025
 2024
 
Net income (loss)$5,020  $(77) $5,132  $(20,110) 
Depreciation and amortization 1,078   1,094   4,327   4,329  
Stock-based compensation 1,960   2,937   6,962   11,467  
Impairment charges 368      368   7,489  
Severance charges    1,183   275   1,908  
Acquisition expense          243  
Shareholder activist related fees       451     
CEO search fees       225     
Other income (59)  (40)  (198)  (152) 
Interest expense (income), net 1,157   1,466   4,941   5,831  
Income tax expense 2,451   2,286   1,818   725  
Adjusted EBITDA 11,975   8,849   24,301   11,730  

FAQ

What were OptimizeRx (OPRX) Q4 2025 revenue and adjusted EBITDA results?

Q4 2025 revenue was $32.2 million and adjusted EBITDA was $12.0 million. According to the company, adjusted EBITDA and GAAP net income reached record levels, reflecting improved margins and operational leverage in the quarter.

How did OptimizeRx (OPRX) perform for the full year 2025 and what was the revenue growth?

Full-year 2025 revenue was $109.4 million, a 19% increase versus 2024. According to the company, full-year adjusted EBITDA was $24.3 million, and operating cash flow improved materially to support higher profitability.

What guidance did OptimizeRx (OPRX) provide for fiscal 2026 revenue and adjusted EBITDA?

OptimizeRx updated 2026 guidance to $109M–$114M revenue and $21M–$25M adjusted EBITDA. According to the company, this reflects expected continued demand amid some near-term market volatility tied to MFN pricing uncertainty.

What is the size and timing of OptimizeRx's (OPRX) share repurchase program?

The board authorized a $10 million share repurchase program effective March 12, 2026, expiring March 15, 2027 or upon completion. According to the company, repurchases may occur in open-market or private transactions using available cash.

How did OptimizeRx (OPRX) cash and operating cash flow change in 2025?

Cash and equivalents rose to $23.4 million at December 31, 2025 and net operating cash provided was $18.7 million for the year. According to the company, improved collections and profitability drove stronger cash generation versus 2024.

What key KPI changes did OptimizeRx (OPRX) report for 2025 that investors should watch?

Net revenue retention declined to 116% and percent revenue from top-20 pharma fell to 52%. According to the company, these KPI shifts reflect client dynamics and a changed definition of top-20 pharma used for comparability.
Optimizerx Corp

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