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Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

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Phio Pharmaceuticals (NASDAQ: PHIO) will participate in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series on Tuesday, June 30, 2026 at 12 PM EDT. CEO and Chairman Robert Bitterman will present the INTASYL siRNA platform and lead candidate PH-762 for cutaneous carcinomas, followed by a live Q&A.

According to Phio, PH-762 is an INTASYL compound that silences the PD-1 gene implicated in various skin cancers and has been evaluated in a Phase 1b trial (NCT# 06014086) for cutaneous squamous cell carcinoma, melanoma and Merkel cell carcinoma as a potential non-surgical treatment.

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AI-generated analysis. How Rhea-AI works. Not financial advice.

Positive

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Negative

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News Market Reaction – PHIO

+1.06%
+1.06% News Effect

On the day this news was published, PHIO gained 1.06%, reflecting a mild positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

What This Means

This announcement highlights continued investor outreach around PH-762 and the INTASYL siRNA platfor...
Analysis

This announcement highlights continued investor outreach around PH-762 and the INTASYL siRNA platform, reinforcing focus on skin cancer indications across a completed Phase 1b trial. Investors may watch upcoming trial design updates while considering ATM and warrant-related overhang.

Peers on Argus

PHIO is moving independently of close biotech peers, with the only momentum-scre...
1 Down

PHIO is moving independently of close biotech peers, with the only momentum-screened peer (BCTX) trading lower and broader peer moves mixed, indicating a stock-specific reaction rather than a sector-wide move.

Historical Context

5 past events · Latest: Jun 25 (Neutral)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jun 25 Investor fireside chat Neutral -5.9% Announcement of Force Family Office virtual fireside chat on siRNA and INTASYL.
Jun 24 Clinical milestone Neutral -1.9% Key milestone with first commercial-scale cGMP production of PH-762 drug substance.
Jun 18 Conference participation Neutral -2.3% Participation in Life Sciences Investor Forum to present INTASYL and PH-762 program.
May 26 Non-deal roadshow Neutral -0.9% Renmark virtual non-deal roadshow featuring INTASYL platform and PH-762 overview.
May 12 Fireside chat Neutral +1.9% Force Family Office chat highlighting PH-762 Phase 1b safety and response data.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent company news, including investor events and program updates, has typically been followed by single-day share declines.

Regulatory & Risk Context

Active S-3 Shelf · $24.5 million · Short Interest: 2.75%
Shelf Active
Short Interest
2.75% of float
0% 15% 30%+
low as of 2026-05-29 Days to cover: 2.96

Reported short interest is relatively low, suggesting limited short-squeeze dynamics and a lower contribution of short covering to share-price volatility.

Active S-3 Shelf Registration 2025-11-20
$24.5 million registered capacity

An effective S-3 shelf supports warrant-related resale of up to 11,763,800 shares; Phio receives cash only upon warrant exercise, potentially funding PH-762 and working capital.

Key Terms

sirna, pd-1, phase 1b, merkel cell carcinoma
4 terms
sirna medical
"Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company"
Small interfering RNA (siRNA) is a short strand of genetic material that binds to and destroys the messenger RNA that carries instructions for making a specific protein, effectively switching that gene off. Investors care because siRNA is a platform for precise medicines: successful trials or approvals can create high-value drugs, while delivery challenges, manufacturing complexity, patent positions and regulatory risk can sharply affect a biotech company's prospects.
pd-1 medical
"PH-762, that silences the PD-1 gene implicated in various forms of skin cancer."
PD-1 is a protein found on certain immune cells that acts like a brake, signaling the immune system to slow down and avoid damaging healthy tissue. Drugs that block PD-1 release that brake so immune cells can better attack cancer cells; because such therapies can produce large clinical benefits, regulatory approvals, trial outcomes, pricing and market uptake for PD-1 drugs can materially affect a drugmaker’s prospects and investor returns.
phase 1b medical
"The Phase 1b trial (NCT# 06014086) evaluated PH-762 for the treatment of"
"Phase 1b" is an early stage in testing a new medical treatment or vaccine, where it is given to a small group of people to evaluate its safety and determine the right dose. For investors, this phase signals progress in development, indicating the treatment is advancing through initial safety checks, which can influence expectations for future success and potential market impact.
merkel cell carcinoma medical
"for the treatment of cutaneous squamous cell carcinoma, melanoma and Merkel cell carcinoma."
Merkel cell carcinoma is a rare, fast-growing form of skin cancer that starts in cells near the base of the skin and often spreads quickly to nearby tissues and organs. For investors, it matters because treatments for this aggressive disease can create high-value opportunities or risks: successful drugs or tests can unlock significant revenue and partnerships, while failed trials or regulatory setbacks can sharply affect a biotech company’s prospects — like a single critical test determining whether a new product succeeds or stalls.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Live Presentation and Q&A: Tuesday, June 30, 2026 12 PM EDT

King of Prussia, Pennsylvania--(Newsfile Corp. - June 26, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio Pharmaceuticals announced today that Robert Bitterman, CEO and Chairman of the Board, will present an overview of the Company's INTASYL® siRNA platform, including its lead clinical candidate PH-762 for the treatment of cutaneous carcinomas. The presentation will be followed by a live Q&A session.

"We are pleased to participate in the Renmark Virtual Non-Deal Roadshow, where we look forward to sharing our perspective on INTASYL and what we believe makes it a differentiated and compelling approach within immuno-oncology," said Robert Bitterman, CEO and Chairman of Phio Pharmaceuticals.

Phio's presentation and live Q&A will take place on Tuesday June 30, 2026, at 12 PM EDT in the live Virtual Non-Deal Roadshow Series hosted by Renmark Financial Communications Inc.

REGISTER HERE: Renmark Virtual Non-Deal Roadshow: NASDAQ - PHIO | Event Registration | Renmark Financial Communications

Please Note: If the link does not work, please copy and paste into your browser. To ensure smooth connectivity, please access the link above using the latest version of Google Chrome.

A replay of the event may be accessed on the Renmark Financial Communications Inc. website at https://www.renmarkfinancial.com/vndrs.

Phio Pharmaceuticals Corp. (Nasdaq: PHIO) is a clinical-stage biopharmaceutical company advancing its proprietary INTASYL® siRNA gene silencing technology to eliminate cancer. Phio's INTASYL compounds are designed to enhance the body's immune cells to more effectively kill cancer cells. Phio's lead clinical development program is an INTASYL compound, PH-762, that silences the PD-1 gene implicated in various forms of skin cancer. The Phase 1b trial (NCT# 06014086) evaluated PH-762 for the treatment of cutaneous squamous cell carcinoma, melanoma and Merkel cell carcinoma. PH-762 is a potential non-surgical treatment for skin cancers.

For additional information, visit the Company's website, www.phiopharma.com.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements can be identified by words such as "intends," "believes," "anticipates," "indicates," "plans," "expects," "suggests," "may," "would," "should," "potential," "designed to," "will," "ongoing," "estimate," "forecast," "target," "predict," "could" and similar references, although not all forward-looking statements contain these words. These statements, which include statements, among other things, regarding the anticipated benefits of our INTASYL™ RNAi platform, the results from our ongoing clinical trials, our expectations that our cash runway will extend into the first half of 2027, our expectations regarding timing of FDA submissions intended to propose and seek guidance for next steps in clinical study design for PH-762, our expectations that such FDA submissions and any related FDA meetings will clarify next steps in advancing the PH-762 development program, details regarding our planned non-clinical toxicology study, and our ability to support ongoing clinical development, operational requirements and strategic initiatives with the capital we currently have on hand, are based only on our current beliefs, expectations and assumptions and are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Our actual results may differ materially from those indicated in the forward-looking statements as a result of a number of important factors, including, but not limited to, the impact of future FDA interactions on the development of our product candidates; the impact to our business and operations by inflationary pressures; recession fears; the development of our product candidates, results from our nonclinical, preclinical and clinical activities, our ability to execute on business strategies, our ability to develop our product candidates with collaboration partners, and the success of any such collaborations, the timeline and duration for advancing our product candidates into clinical development, the timing or likelihood of regulatory filings and approvals, the success of our efforts to commercialize our product candidates if approved, our ability to manufacture and supply our product candidates for clinical activities, and for commercial use if approved, the scope of protection we are able to establish and maintain for intellectual property rights covering our technology platform, our ability to obtain future financing, market and other conditions and those risks identified in our most recent Annual Report on Form 10-K and subsequent Quarterly Reports on Form 10-Q under the caption "Risk Factors" and in other filings the Company periodically makes with the U.S. Securities and Exchange Commission. Readers are urged to review these risk factors and to not act in reliance on any forward-looking statements, as actual results may differ from those contemplated by our forward-looking statements. Phio does not undertake to update forward-looking statements to reflect a change in its views, events or circumstances that occur after the date of this release, except as required by law.

Contact:
Phio Pharmaceuticals Corp.
Jennifer Phillips: jphillips@phiopharma.com
Corporate Affairs

Renmark Financial Communications Inc.
James R. Kautz: jkautz@renmarkfinancial.com
Tel: (416)-644-2020 or (212)-812-7680
www.renmarkfinancial.com

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/302784

FAQ

When is Phio Pharmaceuticals' (NASDAQ: PHIO) Renmark virtual non-deal roadshow in 2026?

Phio Pharmaceuticals' Renmark virtual non-deal roadshow is scheduled for Tuesday, June 30, 2026 at 12 PM EDT. According to Phio, the session will feature a company presentation on INTASYL siRNA technology followed by a live Q&A for investors.

What will Phio Pharmaceuticals present at the June 30, 2026 Renmark roadshow for PHIO stock?

Phio will present an overview of its proprietary INTASYL siRNA platform and lead candidate PH-762. According to Phio, CEO Robert Bitterman will explain how INTASYL aims to enhance immune cells against cancer and discuss PH-762 for treating cutaneous carcinomas.

What is Phio Pharmaceuticals' PH-762 and which cancers has it been studied in?

PH-762 is Phio Pharmaceuticals' lead INTASYL siRNA compound that targets the PD-1 gene implicated in skin cancers. According to Phio, a Phase 1b trial (NCT# 06014086) evaluated PH-762 in cutaneous squamous cell carcinoma, melanoma and Merkel cell carcinoma as a potential non-surgical option.

How does Phio Pharmaceuticals' INTASYL siRNA technology relate to PHIO's cancer pipeline?

INTASYL is Phio Pharmaceuticals' proprietary siRNA gene silencing platform designed to enhance immune cells to kill cancer cells. According to Phio, INTASYL underpins its pipeline, including PH-762, which is being developed as a potential non-surgical treatment for various skin cancers.

Where can investors watch the Phio Pharmaceuticals (PHIO) Renmark non-deal roadshow replay?

Investors can access a replay of Phio Pharmaceuticals' Renmark non-deal roadshow on Renmark Financial Communications' website. According to Phio, the replay will be available at the Renmark virtual non-deal roadshow section, allowing viewers to revisit the INTASYL and PH-762 presentation.

How can investors register for the Phio Pharmaceuticals (PHIO) Renmark virtual roadshow?

Investors can register through the Renmark Virtual Non-Deal Roadshow event page for NASDAQ: PHIO. According to Phio, participants should use the latest version of Google Chrome and may copy and paste the registration link into their browser if direct access issues occur.