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ProMIS Neurosciences Invited to Participate in the 2026 Bloom Burton & Co. Healthcare Investor Conference

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ProMIS Neurosciences (NASDAQ: PMN) will present at the 2026 Bloom Burton & Co. Healthcare Investor Conference in Toronto on April 21-22, 2026. CEO Neil Warma will present on April 21, 2:30–3:00pm ET and be available for one-on-one investor meetings.

The company said a webcast will be available to registered attendees. ProMIS highlighted progress on its PRECISE-AD Phase 1b trial, targeting a six-month interim blinded safety and biomarker analysis in mid-2026, full dosing by year-end 2026, and anticipated unblinded top-line data in early 2027.

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Positive

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Negative

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News Market Reaction – PMN

+2.54%
5 alerts
+2.54% Session close to close
-12.2% Trough in 25 hr 16 min
$123.75M Market Cap
0.6x Rel. Volume

In the Apr 13 session, PMN gained 2.54%, reflecting a moderate positive market reaction. Argus tracked a trough of -12.2% from its starting point during tracking. Our momentum scanner triggered 5 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement centers on PMN’s participation in a major healthcare investor conference and reite...
Analysis

This announcement centers on PMN’s participation in a major healthcare investor conference and reiterates key PRECISE-AD Phase 1b timelines, including a six-month interim analysis in mid-2026 and unblinded top-line data in early 2027. Against a backdrop of recent financing, an effective S-3 shelf for up to $50,000,000 of ATM shares, and mixed historical price reactions to news, attention may focus on execution toward these clinical readouts and subsequent financing choices.

Key Figures

Conference dates: April 21–22, 2026 Company presentation time: 2:30–3:00 pm ET Interim analysis timing: Six-month interim, mid-2026 +2 more
5 metrics
Conference dates April 21–22, 2026 Bloom Burton & Co. Healthcare Investor Conference
Company presentation time 2:30–3:00 pm ET Scheduled slot on April 21, 2026
Interim analysis timing Six-month interim, mid-2026 Blinded safety and biomarker data for PRECISE-AD Phase 1b
Full dosing completion Year-end 2026 Completion of patient dosing in PRECISE-AD Phase 1b
Top-line data timing Early 2027 Unblinded top-line PRECISE-AD Phase 1b results

Historical Context

5 past events · Latest: Mar 25 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 25 Earnings & update Positive -9.1% 2025 results plus PRECISE-AD and financing runway highlights.
Mar 18 Scientific conference Positive -13.0% Posters on ALS and Parkinson’s programs at AD/PD 2026.
Feb 04 Investor conference Neutral -16.3% Participation in Guggenheim biotech summit and investor meetings.
Jan 30 Private placement Positive +17.9% Up to $175M PIPE financing extending cash runway into 2028.
Dec 18 Clinical milestone Positive -5.6% PRECISE-AD Phase 1b enrollment completion with favorable safety profile.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent PMN news, even when fundamentally positive, has often been followed by negative price reactions, with the January 2026 financing a notable positive outlier.

Recent Company History

Over the last few months, PMN has advanced its PRECISE-AD Phase 1b trial, completed enrollment of 144 patients, and secured up to $175M in private placement financing. Multiple investor and scientific conference appearances have been accompanied by sharp one-day declines of 9–16%. Only the January 30, 2026 financing saw a strong positive reaction of +17.95%. Today’s conference-related update fits the pattern of ongoing execution on trial and visibility milestones.

Key Terms

phase 1b, biomarker, blinded
3 terms
phase 1b medical
"our PRECISE-AD Phase 1b clinical trial and welcoming discussions"
"Phase 1b" is an early stage in testing a new medical treatment or vaccine, where it is given to a small group of people to evaluate its safety and determine the right dose. For investors, this phase signals progress in development, indicating the treatment is advancing through initial safety checks, which can influence expectations for future success and potential market impact.
biomarker medical
"six-month interim analysis of blinded safety and biomarker data in mid-2026"
A biomarker is a measurable indicator found in the body, such as in blood or tissues, that provides information about health, disease, or how the body responds to treatment. For investors, biomarkers can signal the potential success or risk of medical products or therapies, influencing the value of related companies and industry trends. They act like signals or clues that help assess the progress of medical advancements and their market impact.
blinded medical
"six-month interim analysis of blinded safety and biomarker data in mid-2026"
Blinded describes a setup in a clinical study where one or more parties — such as patients, doctors, or people analyzing results — do not know which treatment was given, preventing their expectations from influencing outcomes. For investors, blinding matters because it makes trial results more reliable and reduces the risk that positive or negative findings are driven by bias rather than the treatment itself, much like a referee making calls without knowing which team is favored.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Cambridge, Massachusetts--(Newsfile Corp. - April 13, 2026) - ProMIS Neurosciences, Inc. (NASDAQ: PMN), a clinical-stage biotechnology company developing next-generation therapies for Alzheimer's disease (AD) and other neurodegenerative disorders, today announced that Neil Warma, Chief Executive Officer, will participate in the 2026 Bloom Burton & Co. Healthcare Investor Conference.

The conference is being held April 21-22, 2026, at the Metro Toronto Convention Centre in Toronto, Ontario. ProMIS will present on Tuesday, April 21 at 2:30-3:00pm ET and will be available for one-on-one meetings with investors throughout the conference. A webcast of the company presentation will be available to registered attendees via the conference portal.

We look forward to sharing our recent progress related to our PRECISE-AD Phase 1b clinical trial and welcoming discussions with investors and industry partners regarding our differentiated approach to targeting toxic misfolded proteins in Alzheimer's and other neurodegenerative diseases. We are on track to complete a six-month interim analysis of blinded safety and biomarker data in mid-2026. Full patient dosing is expected to be completed by year-end 2026, with presentation of unblinded top-line data anticipated in early 2027.

About ProMIS Neurosciences Inc.

ProMIS Neurosciences is a clinical-stage biotechnology company committed to the discovery and development of therapeutic antibodies and vaccines selective for toxic oligomers associated with the development and progression of neurodegenerative and other misfolded protein diseases. The Company's proprietary target discovery engine, EpiSelect™, has been shown to predict novel targets known as Disease Specific Epitopes (DSEs) on the molecular surface of misfolded proteins that cause neurodegenerative and other misfolded protein diseases, including Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), multiple system atrophy (MSA), and Parkinson's disease (PD). ProMIS has offices in Cambridge, Massachusetts (USA) and Toronto, Ontario (CAN).

About PMN310 and the PRECISE-AD Trial for Alzheimer's Disease (AD)

PMN310, the Company's lead product candidate for the treatment of AD, is a humanized monoclonal antibody that has been designed to selectively target only the toxic oligomers, avoiding plaque, thereby potentially reducing, or eliminating amyloid-related imaging abnormalities (ARIA) liability. In addition, because PMN310 may not be limited by off-target binding or side effects, PMN310 could potentially offer an improved efficacy profile over other amyloid-directed antibody therapeutics. PMN310 was granted Fast Track designation by the U.S. Food and Drug Administration in July 2025.

Based on the encouraging results from the Phase 1a trial (NCT06105528) of PMN310, ProMIS initiated PRECISE-AD, a Phase 1b clinical trial in AD patients. PRECISE-AD (NCT06750432) is a randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability and pharmacokinetics (PK) of multiple ascending doses (5, 10, 20 mg/kg) of intravenous PMN310 in patients with Mild Cognitive Impairment due to AD and mild AD (Stage 3 and Stage 4 AD).

For further information: Visit us at www.promisneurosciences.com

Please submit media inquiries to info@promisneurosciences.com

For Investor Relations, please contact:

Carie Pierce at carie.pierce@promisneurosciences.com

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/290087

FAQ

When and where will ProMIS Neurosciences (PMN) present at the Bloom Burton 2026 conference?

ProMIS will present on April 21, 2026 from 2:30–3:00pm ET at the Metro Toronto Convention Centre. According to the company, CEO Neil Warma will deliver the presentation and meet one-on-one with investors throughout the April 21–22 conference.

Will there be a webcast of the ProMIS Neurosciences (PMN) presentation at Bloom Burton 2026?

Yes, a webcast will be available to registered conference attendees via the event portal. According to the company, registered participants can access the presentation webcast through the conference platform for live viewing and possibly archived access.

What updates will ProMIS Neurosciences (PMN) share about the PRECISE-AD Phase 1b trial at the conference?

ProMIS will discuss recent progress on the PRECISE-AD Phase 1b clinical trial and its approach to targeting toxic misfolded proteins. According to the company, discussion topics include blinded safety, biomarker progress, and trial timelines through 2026–2027.

When does ProMIS expect the PRECISE-AD six-month interim analysis and full patient dosing for PMN?

The company expects a six-month interim blinded safety and biomarker analysis in mid-2026 and full patient dosing by year-end 2026. According to the company, these milestones lead toward reporting unblinded top-line data in early 2027.

What timeline did ProMIS (PMN) give for unblinded top-line PRECISE-AD results?

ProMIS anticipates presenting unblinded top-line PRECISE-AD data in early 2027. According to the company, this timing follows completion of full patient dosing by the end of 2026 and a mid-2026 interim blinded analysis.

How can investors meet ProMIS management at the Bloom Burton & Co. Healthcare Investor Conference?

Investors can attend the April 21–22 conference and request one-on-one meetings with CEO Neil Warma, who will be available throughout the event. According to the company, meeting scheduling is handled via the conference platform for registered attendees.