Palatin Reports Second Quarter Fiscal Year 2026 Financial Results and Provides Corporate Update
Rhea-AI Summary
Palatin (NYSE: PTN) reported fiscal Q2 2026 results and a corporate update on Feb 17, 2026. The company completed an $18.2M public offering, regained NYSE American compliance, and strengthened its cash position to $14.5M as of Dec 31, 2025, with a cash runway beyond Mar 31, 2027.
Palatin advanced its MC4R obesity programs: oral small-molecule PL7737 targets IND filing and Phase 1 initiation in H1 2026; once-weekly peptide MC4R candidates target IND and Phase 1 in H2 2026. The company received upfronts of €2.0M from Boehringer Ingelheim and $3.8M from a PL9643 sublicense.
Positive
- Public offering raised $18.2M on November 12, 2025
- Cash position improved to $14.5M as of December 31, 2025
- PL7737 IND and Phase 1 planned for H1 2026
- Once-weekly peptide MC4R IND planned for H2 2026
- Boehringer collaboration delivered €2.0M upfront and €5.5M milestone
Negative
- Net loss widened to $7.3M for Q2 ended Dec 31, 2025
- Operating expenses increased to $7.4M in Q2
- Reliance on milestone/exercise-based proceeds for future funding
Key Figures
Market Reality Check
Peers on Argus
No peers from the Pharmaceutical Preparation Manufacturing group appeared in the momentum scanner; today’s move in PTN looks stock-specific rather than sector-driven.
Previous Earnings Reports
| Date | Event | Sentiment | Move | Catalyst |
|---|---|---|---|---|
| Nov 13 | Q1 FY26 earnings | Positive | -2.2% | Strong collaboration revenue, public offering close, NYSE trading restored. |
| Feb 13 | Q2 FY25 earnings | Positive | +7.1% | Narrowed net loss and progress on obesity and UC clinical programs. |
| Nov 14 | Q1 FY25 earnings | Negative | -10.1% | Larger net loss and low cash while advancing obesity studies. |
| Oct 01 | FY24 results | Negative | -1.6% | Significant quarterly and annual net losses with ongoing funding needs. |
| May 15 | Q3 FY24 earnings | Positive | -14.1% | Positive Phase 3 and Phase 2 updates despite higher expenses and net loss. |
Earnings updates often led to modest negative moves on average, with occasional sharp selloffs when paired with heavier losses or funding needs.
Across the last five earnings-related releases since May 2024, Palatin has consistently highlighted its melanocortin pipeline and evolving funding position. Updates ranged from successful clinical milestones in obesity, dry eye, and ulcerative colitis to larger net losses and capital raises. Price reactions have been mixed, averaging about -4.17%, with both aligned declines on weaker financials and divergences when positive clinical or partnership news accompanied results. Today’s Q2 FY2026 update continues this pattern of pairing financial results with pipeline and partnering progress.
Historical Comparison
Over the past five earnings releases, PTN’s average move was about -4.17%. Today’s pre-news gain of 3.02% represents a more constructive setup versus that history.
Earnings updates show a shift from funding constraints and larger losses toward strengthened cash via offerings and partnerships, while steadily advancing melanocortin-based obesity and immunology programs.
Market Pulse Summary
This announcement combines Q2 FY2026 results with a clearer picture of Palatin’s obesity-focused strategy. Key points include collaboration and license revenue of $116,036, a net loss of $7.3 million, and cash of $14.5 million supported by a recent $18.2 million public offering and a $3.8 million PL9643 upfront. Historical earnings releases show mixed market reactions, so investors often monitor future milestones, cash runway beyond March 2027, and progress of PL7737 and next-generation MC4R agonists.
Key Terms
mc4r medical
mc1r medical
investigational new drug regulatory
phase 1 medical
warrants financial
reverse stock split financial
hyperphagia medical
AI-generated analysis. Not financial advice.
Advancing differentiated MC4R-based obesity programs into clinical development
- Melanocortin-based obesity therapies targeting rare MC4R pathway disorders with a primary focus on hypothalamic obesity and Prader-Willi syndrome
- Oral small-molecule MC4R agonist PL7737 progressing through IND-enabling toxicology studies, with IND submission and clinical trial initiation planned for the first half of 2026
- Next-generation selective peptide MC4R agonists designed for once-weekly subcutaneous dosing, with IND submission and clinical trial initiation planned for the second half of 2026
- Executed sublicensing of MC1R agonist PL9643 in January 2026, sharpening focus on core obesity portfolio while preserving upside
- Received
in upfront consideration$3.8 million - Eligible for future milestone payments and royalties
- Received
- Strengthened balance sheet through successful public financing
- Completed an
public offering, including the full exercise of the over-allotment option, on November 12, 2025$18.2 million
- Completed an
- Restored NYSE American listing compliance and trading, re-establishing market visibility and liquidity
- Teleconference and webcast to be held on February 17, 2026 at 11:00 AM ET
"Palatin continues to advance its MC4R-based obesity pipeline, with our oral small-molecule MC4R agonist, PL7737, on track to enter clinical evaluation in the first half of this year, and a long-acting peptide MC4R agonist expected to initiate clinical development in the second half of the year," said Carl Spana, Ph.D., President and Chief Executive Officer of Palatin Technologies. "As we progress these programs, we remain focused on delivering differentiated product profiles designed to enhance patient tolerability, including the potential for reduced gastrointestinal side effects, while minimizing off-target effects such as hyperpigmentation. Our preclinical data support the potential applicability of this approach across both rare and select broader obesity indications, with a particular emphasis on neuroendocrine disorders, including hypothalamic obesity and Prader-Willi syndrome. This focus underscores the differentiated nature of our melanocortin platform and our commitment to addressing areas of significant unmet medical need."
"We delivered meaningful execution across our core strategic priorities, highlighted by the successful completion of our
Obesity Program Update
The obesity program is focused on developing differentiated MC4R agonists designed to enhance patient tolerability, including the potential for reduced gastrointestinal side effects, while minimizing off-target effects such as hyperpigmentation.
Planned clinical studies are expected to enroll and evaluate patients with hypothalamic obesity and Prader-Willi syndrome, addressing populations with significant unmet medical need.
- PL7737 (oral MC4R agonist):
- Demonstrated meaningful weight loss, oral bioavailability across relevant preclinical models.
- IND-enabling toxicology studies are progressing as planned, with an IND submission and initiation of a Phase 1 single- and multiple-ascending dose (SAD/MAD) trial anticipated in the first half of 2026.
- Next-generation selective peptide MC4R agonists:
- Designed for once-weekly subcutaneous dosing, with an IND submission and initiation of a Phase 1 SAD/MAD trial targeted for the second half of 2026.
Out-Licensing Programs Update
- Retinal diseases (MCR agonists) – Collaboration with Boehringer Ingelheim, providing near-term non-dilutive capital and substantial downstream value potential.
- Received an upfront payment of
€2.0 million ( ) in August 2025.$2.3 million - Achieved
€5.5 million ( ) research milestone in September 2025, reflecting continued program progress.$6.5 million - Eligible to receive up to
€12.5 million ( ) in additional near-term research milestones and up to$14.5 million €260 million ( ) in development, regulatory, and commercial milestones, in addition to tiered royalties on net sales.$307.0 million
- Received an upfront payment of
- PL9643 (MC1R agonist) - Dry Eye Disease – Sublicensing agreement with Altanispac Labs, providing near-term value, while preserving long-term participation.
- Received
in upfront consideration in January 2026, strengthening the Company's balance sheet.$3.8 million - Eligible to receive additional future payments under the sublicensing agreement, including asset disposition and commercialization milestones, as well as royalties on net sales.
- Received
- PL8177 (MCR agonist) - Ulcerative Colitis, advancing toward strategic partnering following clinical validation.
- Delivered positive Phase 2 proof-of-concept results, supporting the therapeutic potential of the program.
- Active out-licensing discussions are underway, reflecting interest from potential partners in the asset's clinical profile and commercial potential.
- Diabetic nephropathy (MCR agonists) - Building on encouraging clinical data to advance partnering opportunities.
- Reported positive Phase 2 open-label results, supporting the therapeutic potential of the program.
- Ongoing out-licensing discussions continue to explore strategic pathways to maximize the value of the asset.
Corporate Update
Public Offering
On November 12, 2025, Palatin announced the closing of its upsized
Each Series J Warrant has an exercise price of
The gross proceeds from the Offering, before deducting the underwriting discounts and commissions and offering expenses, were approximately
The Company intends to use the net proceeds from the Offering to support the development of its obesity program and for working capital and general corporate purposes.
NYSE American
As a result of the closing of the Offering, the Company regained compliance with NYSE American continued listing standard of the NYSE American Company Guide and all applicable requirements for continued listing on NYSE American. Effective November 12, 2025, the Company's common stock resumed trading on the NYSE American under the symbol "PTN."
Fiscal Second Quarter Ended December 31, 2025, Financial Results
Revenue
For the second quarter ended December 31, 2025, Palatin recognized
Operating Expenses
Total operating expenses were
Other Income / (Expense)
Total other income (expense), net was
Cash Flows
Palatin's net cash used in operations was
Net Loss
Palatin reported a net loss for the second quarter ended December 31, 2025, of
Cash Position
As of December 31, 2025, Palatin's cash and cash equivalents were
In January 2026, as partial consideration for the rights to PL9643, the sublicensing agreement provided for upfront consideration in the form of non-cash debt cancellation of approximately
Conference Call / Webcast
Palatin will host a conference call and audio webcast on February 17, 2026, at 11:00 a.m. ET to discuss the results of operations in greater detail and provide an update on corporate developments. Individuals interested in listening to the conference call live can dial 1-888-506-0062 (US) or 1-973-528-0011 (International), Participant Access Code: 967781. The audio webcast and replay can be accessed by logging on to the "Investor-Webcasts" section of Palatin's website at http://www.palatin.com. A telephone and audio webcast replay will be available one hour after the completion of the call. To access the telephone replay, dial 1-877-481-4010 (US) or 1-919-882-2331 (International), Replay Passcode 83633. The webcast and telephone replay will be available through March 3, 2026.
Melanocortin-4 Receptor Agonists Effect on Obesity
Hypothalamic neurons expressing the melanocortin-4 receptor (MC4R) play a central role in regulating stored energy, food intake, and body weight. Genetic mutations that inhibit signaling through the MC4R pathway lead to hyperphagia, decreased energy expenditure and early-onset obesity; such mutations have been identified as the cause of several rare genetic obesity disorders. MC4R agonism represents an attractive target for potential obesity treatments.
About Hypothalamic Obesity
Hypothalamic obesity is a rare and severe form of obesity caused by dysfunction or damage to the hypothalamus, the region of the brain that regulates appetite, satiety, and energy balance. Hypothalamic obesity can occur as an acquired condition, most commonly after surgery or radiation therapy for brain tumors such as craniopharyngioma, or as a congenital disorder associated with genetic syndromes and developmental abnormalities affecting hypothalamic function. Individuals with hypothalamic obesity typically experience rapid, excessive weight gain, uncontrollable hunger, and profound metabolic disturbances that are resistant to conventional diet, exercise, and behavioral interventions. There are currently no approved pharmacologic treatments specifically indicated for hypothalamic obesity, representing a significant unmet medical need.
About Prader-Willi Syndrome
Prader-Willi syndrome (PWS) is a rare, complex genetic neurodevelopmental disorder caused by the loss of function of specific genes on chromosome 15. The condition is characterized by hyperphagia, impaired satiety, developmental delays, reduced muscle tone, endocrine abnormalities, and behavioral challenges. Individuals with PWS typically develop an intense and persistent drive to eat, beginning in early childhood, which can lead to severe obesity and related metabolic complications if not strictly managed. Current treatment approaches focus primarily on symptom management, including nutritional supervision, behavioral interventions, and growth hormone therapy, but there are no approved pharmacologic therapies that directly address hyperphagia or the underlying hypothalamic dysfunction associated with PWS. As a result, PWS represents a significant unmet medical need.
About Melanocortin Receptor Agonists
The melanocortin receptor ("MCR") system has effects on inflammation, immune system responses, metabolism, food intake, and sexual function. There are five melanocortin receptors, MC1R through MC5R. Modulation of these receptors, through use of receptor-specific agonists, which activate receptor function, or receptor-specific antagonists, which block receptor function, can have medically significant pharmacological effects.
About Palatin
Palatin is a biopharmaceutical company developing first-in-class medicines based on molecules that modulate the activity of the melanocortin receptor systems, with targeted, receptor-specific product candidates for the treatment of diseases with significant unmet medical need and commercial potential. Palatin's strategy is to develop products and then form marketing collaborations with industry leaders to maximize their commercial potential. For more information, visit the company's website at www.palatin.com and follow us on X (formally Twitter) @PalatinTech.
Forward-looking Statements
Statements in this press release that are not historical facts, including statements about future expectations of Palatin Technologies, Inc., such as statements about Palatin products in development, clinical trial results, potential actions by regulatory agencies, regulatory plans, development programs, proposed indications for product candidates, and market potential for product candidates are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and as that term is defined in the Private Securities Litigation Reform Act of 1995. Palatin intends that such forward-looking statements be subject to the safe harbors created thereby. Such forward-looking statements involve known and unknown risks, uncertainties and other factors that could cause Palatin's actual results to be materially different from its historical results or from any results expressed or implied by such forward-looking statements. Palatin's actual results may differ materially from those discussed in the forward-looking statements for reasons including, but not limited to, results of clinical trials, regulatory actions by the FDA and other regulatory and the need for regulatory approvals, Palatin's ability to fund development of its technology and establish and successfully complete clinical trials, the length of time and cost required to complete clinical trials and submit applications for regulatory approvals, products developed by competing pharmaceutical, biopharmaceutical and biotechnology companies, commercial acceptance of Palatin's products, and other factors discussed in Palatin's periodic filings with the Securities and Exchange Commission. Palatin is not responsible for updating events that occur after the date of this press release.
Palatin Technologies® is a registered trademark of Palatin Technologies, Inc.
PALATIN TECHNOLOGIES, INC. | |||||||
and Subsidiary | |||||||
Consolidated Statements of Operations | |||||||
(unaudited) | |||||||
Three Months Ended December 31, | Six Months Ended December 31, | ||||||
2025 | 2024 | 2025 | 2024 | ||||
REVENUES | |||||||
Collaboration and license | $ 116,036 | $ - | $ 8,963,586 | $ - | |||
OPERATING EXPENSES | |||||||
Research and development | 4,319,767 | 3,429,479 | 6,845,533 | 9,173,233 | |||
General and administrative | 3,124,817 | 1,681,844 | 4,785,548 | 3,702,775 | |||
Gain on sale of Vyleesi | - | (2,500,000) | - | (2,500,000) | |||
Total operating expenses | 7,444,584 | 2,611,323 | 11,631,081 | 10,376,008 | |||
Loss from operations | (7,328,548) | (2,611,323) | (2,667,495) | (10,376,008) | |||
OTHER INCOME (EXPENSE) | |||||||
Investment income | 65,185 | 29,044 | 83,668 | 107,620 | |||
Foreign currency transaction gain | - | 143,600 | - | 12,000 | |||
Interest expense | (498) | (3,803) | (2,500) | (9,743) | |||
Total other income (expense), net | 64,687 | 168,841 | 81,168 | 109,877 | |||
NET LOSS | $ (7,263,861) | $ (2,442,482) | $ (2,586,327) | $ (10,266,131) | |||
Basic and diluted net loss per common share | $ (2.86) | $ (5.92) | $ (1.47) | $ (25.36) | |||
Weighted average number of common shares | 2,539,632 | 412,697 | 1,755,641 | 404,799 | |||
PALATIN TECHNOLOGIES, INC. | |||
and Subsidiary | |||
Consolidated Balance Sheets | |||
(unaudited) | |||
December 31, 2025 | June 30, 2025 | ||
ASSETS | |||
Current assets: | |||
Cash and cash equivalents | $ 14,476,162 | $ 2,564,265 | |
Accounts Receivable | 1,636,325 | - | |
Other receivables | - | 29,468 | |
Prepaid expenses and other current assets | 1,354,992 | 325,695 | |
Total current assets | 17,467,479 | 2,919,428 | |
Property and equipment, net | 113,485 | 129,444 | |
Right-of-use assets - operating leases | 346,764 | 161,166 | |
Other assets | - | 56,916 | |
Total assets | $ 17,927,728 | $ 3,266,954 | |
LIABILITIES AND STOCKHOLDERS' DEFICIENCY | |||
Current liabilities: | |||
Accounts payable | $ 5,453,080 | $ 6,998,806 | |
Accrued expenses | 659,841 | 881,412 | |
Short-term operating lease liabilities | 219,727 | 129,812 | |
Total current liabilities | 6,332,648 | 8,010,030 | |
Long-term operating lease liabilities | 129,061 | 33,969 | |
Total liabilities | 6,461,709 | 8,043,999 | |
Stockholders' equity (deficiency): | |||
Preferred stock of | |||
and outstanding designated as follows: | |||
Series A Convertible: authorized 4,030 shares as of December 31, 2025: issued | |||
and outstanding 4,030 shares as of December 31, 2025 and June 30, 2025 | 40 | 40 | |
Series D Convertible: authorized 3,400 shares as of December 31, 2025: issued | |||
and outstanding 3,400 shares as of December 31, 2025 and June 30, 2025 | 34 | 34 | |
Common stock of | |||
issued and outstanding 1,757,199 shares as of December 31, 2025 and 929,597 | 17,572 | 9,296 | |
Additional paid-in capital | 473,108,599 | 454,287,484 | |
Accumulated deficit | (461,660,226) | (459,073,899) | |
Total stockholders' equity (deficiency) | 11,466,019 | (4,777,045) | |
Total liabilities and stockholders' equity (deficiency) | $ 17,927,728 | $ 3,266,954 | |
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SOURCE Palatin Technologies, Inc.