Quantum-Si Reports Second Quarter 2026 Financial Results and Provides Proteus™ Development Update
Rhea-AI Summary
Quantum-Si (Nasdaq: QSI) reported second quarter 2026 revenue of $344 thousand, down from $591 thousand a year earlier, during its transition from the Platinum platform to the anticipated Proteus protein sequencing system. Gross profit was $172 thousand with a 50% gross margin.
Total operating expenses were $25.8 million versus $30.5 million in Q2 2025, and net loss narrowed to $23.5 million from $28.8 million. Adjusted EBITDA was negative $21.2 million, compared to negative $22.2 million in the prior-year quarter. As of June 30, 2026, cash, cash equivalents and marketable securities totaled $169.9 million.
The company updated the anticipated commercial launch of Proteus to Q2 2027 to allow an additional integrated instrument design cycle and announced a workforce reduction of about 20%, expected to yield roughly $12 million in annualized operating expense savings and extend its cash runway into Q4 2028. Quantum-Si reiterated 2026 guidance, including approximately $1.0 million in revenue and adjusted total operating expenses of $98.0 million or less, and highlighted an estimated $4 billion annual non-human proteomics market opportunity for Proteus.
Positive
- Net loss narrowed to $23.5M from $28.8M year over year
- Total operating expenses fell to $25.8M from $30.5M in Q2
- Annualized expense savings of about $12M from cost reductions
- Cash, cash equivalents and securities of $169.9M at June 30, 2026
- Cash runway extended into Q4 2028 under updated operating plan
- Reiterated 2026 guidance: ~$1.0M revenue and ≤$98M adjusted opex
Negative
- Q2 2026 revenue declined to $344K from $591K year over year
- First-half 2026 revenue $602K versus $1.4M in prior-year period
- Proteus anticipated commercial launch pushed back to Q2 2027
- Approximately 20% workforce reduction to align expenses and timeline
- Q2 2026 net loss remains large at $23.5M
- Adjusted EBITDA negative $21.2M in Q2 and $41.2M year to date
News Explained
At
Key Figures
Previous Earnings Reports
| Date | Event | Sentiment | 24h Move | Catalyst |
|---|---|---|---|---|
| May 07 | Q1 earnings report | Positive | -7.5% | Reported Q1 results and Proteus milestones while retaining a year-end 2026 launch target |
| Mar 03 | Q4 earnings report | Positive | -4.0% | Reported 2025 results, Proteus pricing, and 2026 financial guidance |
| Nov 05 | Q3 earnings report | Negative | -8.3% | Reported continuing losses, higher operating expenses, and Proteus development progress |
| Aug 05 | Q2 earnings report | Negative | -4.9% | Reported lower earnings quality amid funding challenges and a capital raise |
| May 15 | Q1 earnings report | Positive | +0.0% | Reported revenue growth, product deliveries, and expanded international distribution |
24h Move is the share-price change in the day after each event; other market factors may also have contributed.
QSI's tag-specific earnings announcements were followed by negative 24-hour reactions in four of five available events, with an average move of -4.95%.
Key Terms
single-molecule protein sequencing technical
adjusted ebitda financial
non-gaap financial measures financial
marketable securities financial
AI-generated analysis. How Rhea-AI works. Not financial advice.
Company updates anticipated commercial launch of Proteus to Q2 2027, cost-reduction actions expected to extend cash runway into Q4 2028 and highlights estimated new market opportunities for protein sequencing
BRANFORD, Conn., Aug. 13, 2026 (GLOBE NEWSWIRE) -- Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through single-molecule protein sequencing, today announced financial results for the second quarter ended June 30, 2026.
Press Release Highlights
- Reported second quarter 2026 revenue of
$344 thousand during the Proteus transition period. - Updated anticipated Proteus launch timeline to Q2 2027 to incorporate an additional integrated instrument design cycle focused on manufacturing readiness, system repeatability, and customer experience at launch.
- Highlighted an estimated
$4 billion non-human proteomics market opportunity identified through on-going Platinum commercialization activities. - Announced a reduction in force of approximately
20% of the Company’s workforce to align resources and spending with the updated Proteus launch timeline. - Extended cash runway into Q4 2028 from Q2 2028.
“Our conviction in Proteus remains strong. Testing of our integrated instruments has generated sequencing data that reinforces our confidence in the underlying technology,” said Jeff Hawkins, president and Chief Executive Officer of Quantum-Si. “As we advanced the program, we concluded that adding an additional integrated instrument design cycle was the most responsible path to strengthen manufacturing readiness, improve system performance, and ensure a successful customer experience at launch. While this decision extends the timeline, we believe it significantly improves our readiness for commercialization and positions Proteus to create the maximum long-term value for customers, shareholders, and the broader scientific community.”
Hawkins continued, “As we continue to advance Proteus toward commercialization, our ongoing customer work is also expanding our view of the platform’s addressable markets. Over the past few months, we have been working with multiple customers applying protein sequencing to agricultural applications, pathogen detection and typing, and viral protein surveillance applications. Based on this work, we believe the non-human proteomics market opportunity for Proteus is substantial, at more than
Second Quarter 2026 Financial Results
For the second quarter of 2026, the Company recorded revenue of
Total operating expenses were
The Company also announced cost-reduction actions, including a reduction in force affecting approximately
Net loss was
As of June 30, 2026, the Company’s cash, cash equivalents and investments in marketable securities were
2026 Financial Guidance
For the full year 2026, the Company reiterated the following financial guidance, as initially issued on March 3, 2026:
| Revenue: | Approximately |
| Adjusted total operating expenses: | |
| Total cash usage: | |
The Company continues to view 2026 as a transition year ahead of the anticipated Proteus launch. The updated anticipated launch timing of Q2 2027 is intended to allow the Company to complete additional integrated instrument design and testing work, advance verification and validation activities, and further prepare for manufacturing and commercial launch. The Company expects 2026 revenue to continue to reflect the transition from Platinum to Proteus, including customer purchasing behavior, installed-base consumable activity, and customer planning for the anticipated new platform.
Adjusted total operating expenses are expected to support Proteus development, platform integration, verification and validation activities, chemistry and workflow development, and launch preparation. The Company plans to manage spending against the revised launch timeline while maintaining the resources needed to advance Proteus toward commercialization.
Total cash usage is expected to include Proteus development, selected inventory investments, and commercial readiness activities supporting the updated Q2 2027 anticipated launch timing.
The Company does not provide a reconciliation of forward-looking adjusted total operating expenses to total operating expenses, the most directly comparable GAAP measure, because stock-based compensation, restructuring costs and other excluded items are dependent on future events and are not reasonably available without unreasonable efforts. These items could have a material effect on GAAP operating expenses.
The Company believes its cash, cash equivalents and investments in marketable securities of
Webcast and Conference Call Information
Quantum-Si will host a conference call to discuss its second quarter 2026 financial results on Thursday, August 13, 2026, at 4:30 p.m. Eastern Time. Individuals interested in listening to the conference call may do so by joining the live webcast in the Investors section of the Quantum-Si website under Events & Presentations. Alternatively, individuals may register here to receive a dial-in number and personalized PIN to participate in the call. An archived webcast of the event will be available for replay following the event.
About Quantum-Si Incorporated
Quantum-Si is transforming proteomics with a benchtop platform that brings single-molecule protein analysis to every lab, everywhere. The Company’s platform enables real-time kinetic-based detection and allows researchers to move beyond traditional, multistep workflows and directly access dynamic, functional protein insights with unparalleled resolution. By making protein analysis simpler, faster, and more informative, Quantum-Si is accelerating proteomic discoveries to improve the way we live. Learn more at quantum-si.com or follow us on LinkedIn or X.
Use of Non-GAAP Financial Measures
This press release presents the non-GAAP financial measures “adjusted total operating expenses” and “adjusted EBITDA.” The most directly comparable measures for these non-GAAP financial measures are total operating expenses and net loss. The Company has included below adjusted total operating expenses, which presents the Company’s total operating expenses after excluding stock-based compensation, legal settlement expense, net of insurance proceeds, restructuring costs and other non-recurring operating expenses. In addition, adjusted EBITDA further excludes interest, taxes, depreciation, amortization, dividend and interest income, changes in fair value of warrant liabilities and other income or expense.
A discussion of the reasons why management believes that the presentation of non-GAAP financial measures provides useful information to investors regarding the Company’s financial condition and results of operations is included as Exhibit 99.2 to the Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission (the “SEC”) on August 13, 2026.
Forward Looking Statements
This press release includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. The actual results of the Company may differ from its expectations, estimates, and projections and, consequently, you should not rely on these forward-looking statements as predictions of future events. Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,” “intend,” “plan,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “continue,” and similar expressions (or the negative versions of such words or expressions) are intended to identify such forward-looking statements. These forward-looking statements include, without limitation, the Company’s expectations with respect to future performance and development and commercialization of products, services and applications, its anticipated cash runway, the anticipated timing of product launches and product capabilities (including Proteus), the Company’s current belief regarding remaining technical challenges associated with Proteus commercialization, the expected timing and successful completion of system integration, optimization, verification, validation and launch-readiness activities, the expected benefits of the Company’s development-process, organizational and cost-control actions, including the reduction in force, and any financial guidance. These forward-looking statements involve significant risks and uncertainties that could cause the actual results to differ materially from those discussed in the forward-looking statements. Many of these factors are outside the Company’s control and are difficult to predict. Factors that may cause such differences include, but are not limited to: the inability to maintain the listing of the Company’s Class A common stock on The Nasdaq Stock Market; the ability of the Company to grow and manage growth and retain its key employees; the Company’s ongoing leadership transitions and succession planning; the Company’s ability to successfully implement organizational changes, including workforce reductions, cost-control actions and development-process improvements, without disrupting product development, launch readiness, employee retention or customer engagement; the possibility that additional technical, integration, performance, reliability, verification, validation or launch-readiness challenges may arise or take longer or cost more to address than expected; changes in applicable laws or regulations; the ability of the Company to raise financing in the future; the success, cost and timing of the Company’s product development and commercialization activities, including the use and benefit of artificial intelligence in these and other activities; the commercialization and adoption of the Company’s existing products and the success of any product the Company may offer in the future, including Proteus; the potential attributes and benefits of the Company’s commercialized Platinum protein sequencing instruments and kits and the Company’s other products (including Proteus) once commercialized; the Company’s ability to obtain and maintain regulatory approval for its products, and any related restrictions and limitations of any approved product; the Company’s ability to identify, in-license or acquire additional technology; the Company’s ability to maintain its existing lease, license, manufacture and supply agreements; the Company’s ability to compete with other companies currently marketing or engaged in the development or commercialization of products and services that serve customers engaged in proteomic analysis, many of which have greater financial and marketing resources than the Company; the size and growth potential of the markets for the Company’s products and services, and its ability to serve those markets once commercialized, either alone or in partnership with others; the Company’s estimates regarding future expenses, future revenue, capital requirements and needs for additional financing; the Company’s financial performance; the Company’s defense and initiation of litigation matters; and other risks and uncertainties described under “Risk Factors” in the Company’s most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q and in the Company’s other filings with the SEC. The Company cautions that the foregoing list of factors is not exclusive. The Company cautions readers not to place undue reliance upon any forward-looking statements, which speak only as of the date made. The Company does not undertake or accept any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements to reflect any change in its expectations or any change in events, conditions, or circumstances on which any such statement is based.
| QUANTUM-SI INCORPORATED CONDENSED CONSOLIDATED BALANCE SHEETS (in thousands, except share and par value amounts) (unaudited) | |||||||
| June 30, 2026 | December 31, 2025 | ||||||
| Assets | |||||||
| Current assets: | |||||||
| Cash and cash equivalents | $ | 23,653 | $ | 21,639 | |||
| Marketable securities, current | 88,088 | 141,271 | |||||
| Accounts receivable, net of allowance of | 57 | 561 | |||||
| Legal settlement insurance receivable | — | 4,638 | |||||
| Inventory | 2,027 | 3,197 | |||||
| Prepaid expenses and other current assets | 5,262 | 4,554 | |||||
| Total current assets | 119,087 | 175,860 | |||||
| Restricted cash, non-current | 2,202 | — | |||||
| Marketable securities, non-current | 58,122 | 52,855 | |||||
| Property and equipment, net | 10,905 | 13,194 | |||||
| Operating lease right-of-use assets | 2,707 | 3,464 | |||||
| Other assets | 552 | 234 | |||||
| Total assets | $ | 193,575 | $ | 245,607 | |||
| Liabilities and stockholders’ equity | |||||||
| Current liabilities: | |||||||
| Accounts payable | $ | 1,591 | $ | 1,623 | |||
| Accrued payroll and payroll-related costs | 2,955 | 5,903 | |||||
| Accrued contracted services | 3,210 | 3,356 | |||||
| Accrued legal settlement liability | — | 8,000 | |||||
| Accrued expenses and other current liabilities | 2,347 | 1,505 | |||||
| Warrant liabilities | — | 794 | |||||
| Current portion of operating lease liabilities | 1,843 | 1,844 | |||||
| Total current liabilities | 11,946 | 23,025 | |||||
| Operating lease liabilities | 1,410 | 2,322 | |||||
| Other long-term liabilities | 18 | 34 | |||||
| Total liabilities | 13,374 | 25,381 | |||||
| Stockholders’ equity: | |||||||
| Class A Common stock, | 20 | 20 | |||||
| Class B Common stock, | 2 | 2 | |||||
| Additional paid-in capital | 923,805 | 918,190 | |||||
| Accumulated other comprehensive loss | (441 | ) | (6 | ) | |||
| Accumulated deficit | (743,185 | ) | (697,980 | ) | |||
| Total stockholders’ equity | 180,201 | 220,226 | |||||
| Total liabilities and stockholders’ equity | $ | 193,575 | $ | 245,607 | |||
| QUANTUM-SI INCORPORATED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (in thousands, except per share amounts) (unaudited) | |||||||||||||||
| Three months ended June 30, | Six months ended June 30, | ||||||||||||||
| 2026 | 2025 | 2026 | 2025 | ||||||||||||
| Revenue | |||||||||||||||
| Product | $ | 314 | $ | 558 | $ | 530 | $ | 1,366 | |||||||
| Service | 30 | 33 | 72 | 67 | |||||||||||
| Total revenue | 344 | 591 | 602 | 1,433 | |||||||||||
| Cost of revenue | |||||||||||||||
| Product | 172 | 230 | 349 | 567 | |||||||||||
| Service | — | 10 | 7 | 29 | |||||||||||
| Total cost of revenue | 172 | 240 | 356 | 596 | |||||||||||
| Gross profit | 172 | 351 | 246 | 837 | |||||||||||
| Operating expenses: | |||||||||||||||
| Research and development | 15,824 | 15,213 | 30,311 | 28,930 | |||||||||||
| Selling, general and administrative | 9,977 | 11,896 | 19,617 | 23,777 | |||||||||||
| Legal settlement expense, net of insurance proceeds | — | 3,362 | — | 3,362 | |||||||||||
| Total operating expenses | 25,801 | 30,471 | 49,928 | 56,069 | |||||||||||
| Loss from operations | (25,629 | ) | (30,120 | ) | (49,682 | ) | (55,232 | ) | |||||||
| Dividend income | 114 | 155 | 245 | 376 | |||||||||||
| Interest income | 1,544 | 2,157 | 3,288 | 4,483 | |||||||||||
| Change in fair value of warrant liabilities | 437 | (994 | ) | 794 | 2,407 | ||||||||||
| Other (expense) income, net | — | (14 | ) | 28 | (28 | ) | |||||||||
| Loss before (provision) benefit for income taxes | (23,534 | ) | (28,816 | ) | (45,327 | ) | (47,994 | ) | |||||||
| (Provision) benefit for income taxes | — | (20 | ) | 122 | (31 | ) | |||||||||
| Net loss | $ | (23,534 | ) | $ | (28,836 | ) | $ | (45,205 | ) | $ | (48,025 | ) | |||
| Net loss per common share attributable to common stockholders, basic and diluted | $ | (0.11 | ) | $ | (0.16 | ) | $ | (0.21 | ) | $ | (0.26 | ) | |||
| Weighted-average shares used to compute net loss per share attributable to common stockholders, basic and diluted | 217,802 | 183,625 | 217,141 | 182,968 | |||||||||||
| Other comprehensive income (loss) | |||||||||||||||
| Net unrealized loss on marketable securities, net of tax | $ | (37 | ) | $ | (54 | ) | $ | (341 | ) | $ | (107 | ) | |||
| Foreign currency translation adjustment | (22 | ) | 16 | (94 | ) | 22 | |||||||||
| Total other comprehensive loss, net of tax | (59 | ) | (38 | ) | (435 | ) | (85 | ) | |||||||
| Comprehensive loss | $ | (23,593 | ) | $ | (28,874 | ) | $ | (45,640 | ) | $ | (48,110 | ) | |||
| QUANTUM-SI INCORPORATED RECONCILIATIONS OF U.S. GAAP TO NON-GAAP FINANCIAL MEASURES (in thousands) (unaudited) | |||||||||||||||
| Three months ended June 30, | Six months ended June 30, | ||||||||||||||
| 2026 | 2025 | 2026 | 2025 | ||||||||||||
| Net loss | $ | (23,534 | ) | $ | (28,836 | ) | $ | (45,205 | ) | $ | (48,025 | ) | |||
| Adjustments to reconcile to EBITDA: | |||||||||||||||
| Dividend income | (114 | ) | (155 | ) | (245 | ) | (376 | ) | |||||||
| Interest income | (1,544 | ) | (2,157 | ) | (3,288 | ) | (4,483 | ) | |||||||
| Depreciation and amortization | 1,229 | 1,191 | 2,454 | 2,108 | |||||||||||
| Income tax provision (benefit) | — | 20 | (122 | ) | 31 | ||||||||||
| EBITDA | (23,963 | ) | (29,937 | ) | (46,406 | ) | (50,745 | ) | |||||||
| Adjustments to reconcile to Adjusted EBITDA: | |||||||||||||||
| Change in fair value of warrant liabilities | (437 | ) | 994 | (794 | ) | (2,407 | ) | ||||||||
| Stock-based compensation | 3,050 | 2,789 | 5,615 | 5,151 | |||||||||||
| Legal settlement expense, net of insurance proceeds | — | 3,362 | — | 3,362 | |||||||||||
| Restructuring costs | 195 | 186 | 390 | 320 | |||||||||||
| Other non-recurring operating expenses | — | 367 | — | 611 | |||||||||||
| Other expense (income), net | — | 14 | (28 | ) | 28 | ||||||||||
| Adjusted EBITDA | $ | (21,155 | ) | $ | (22,225 | ) | $ | (41,223 | ) | $ | (43,680 | ) | |||
| Three months ended June 30, | Six months ended June 30, | ||||||||||||||
| 2026 | 2025 | 2026 | 2025 | ||||||||||||
| Total operating expenses | $ | 25,801 | $ | 30,471 | $ | 49,928 | $ | 56,069 | |||||||
| Adjustments to reconcile to Adjusted total operating expenses: | |||||||||||||||
| Stock-based compensation | (3,050 | ) | (2,789 | ) | (5,615 | ) | (5,151 | ) | |||||||
| Legal settlement expense, net of insurance proceeds | — | (3,362 | ) | — | (3,362 | ) | |||||||||
| Restructuring costs | (195 | ) | (186 | ) | (390 | ) | (320 | ) | |||||||
| Other non-recurring operating expenses | — | (367 | ) | — | (611 | ) | |||||||||
| Adjusted total operating expenses | $ | 22,556 | $ | 23,767 | $ | 43,923 | $ | 46,625 | |||||||
Contacts
Investor and Media:
Jeff Keyes
Chief Financial Officer
ir@quantum-si.com
Source: Quantum-Si Incorporated
