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Rani Therapeutics Appoints Jesper Høiland as Head of Strategy to Advance Corporate and Pipeline Prioritization

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Rani Therapeutics (Nasdaq: RANI) named Jesper Høiland Head of Strategy effective March 25, 2026. He joins after advising Rani since 2023 and brings 30+ years of pharmaceutical leadership with experience in obesity and metabolic disease.

Høiland will prioritize internal programs, evaluate therapeutic opportunities, and support partnering and business development for the RaniPill® oral biologics platform.

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Positive

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Negative

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News Market Reaction – RANI

-5.26%
9 alerts
-5.26% Session close to close
+23.8% Peak Tracked
-7.0% Trough Tracked
$139.14M Market Cap
0.8x Rel. Volume

In the Mar 26 session, RANI declined 5.26%, reflecting a notable negative market reaction. Argus tracked a peak move of +23.8% during that session. Argus tracked a trough of -7.0% from its starting point during tracking. Our momentum scanner triggered 9 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock moved -5.3% in the session following this news. A negative reaction despite a senior strat...
Analysis

The stock moved -5.3% in the session following this news. A negative reaction despite a senior strategy hire fits a pattern where Rani’s operational updates have met with cautious trading. The stock sat at $1.14, far below the $3.87 52-week high, and prior positive milestones sometimes coincided with flat or down moves. With an S-3 resale registration in place and past financing-driven dilution, sentiment could remain sensitive to execution on partnerships and obesity-program milestones.

Key Figures

Industry experience: More than 30 years Adviser tenure: Since 2023 Preclinical data timing: Last year +3 more
6 metrics
Industry experience More than 30 years Global pharmaceutical leadership experience of Jesper Høiland
Adviser tenure Since 2023 Period Jesper Høiland has served as strategic adviser to Rani
Preclinical data timing Last year Timing of preclinical semaglutide and GLP-1/GLP-2 data referenced
1-day price move -7.02% Price change in the 24h before this news
52-week range $0.387 – $3.87 52-week low and high before this news
Market cap $103,404,040 Equity value prior to this announcement

Historical Context

5 past events · Latest: Mar 19 (Neutral)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 19 Earnings date set Neutral -1.7% Announcement of timing for Q4 and full-year 2025 results and call.
Jan 28 Executive promotion Positive -2.9% Promotion of Alireza Javadi, Ph.D. to Chief Technical Officer.
Jan 08 Phase 1 trial start Positive +0.0% Initiation of Phase 1 RT-114 RaniPill® study for obesity with ProGen.
Nov 24 Conference participation Neutral -3.0% Participation in the 8th Annual Evercore Healthcare Conference.
Nov 06 Earnings and financing Negative -11.0% Q3 2025 results with tight cash, large loss, and major financing updates.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news, including management changes, clinical progress, and financing-related disclosures, has often been followed by flat to negative one-day moves, even when the underlying updates were operationally positive.

Recent Company History

Over the last six months, Rani has balanced corporate development with capital and pipeline milestones. A Nov 6, 2025 Q3 update combined a large Chugai collaboration and an oversubscribed $60.3 million private placement with tight liquidity, and the stock fell 11.01%. Subsequent items—an Evercore conference appearance, initiation of a Phase 1 obesity trial RT-114, and internal leadership promotions—saw flat to modestly negative reactions. An earnings-date announcement on Mar 19, 2026 also coincided with a small decline, suggesting the market has not rewarded recent milestones in the near term.

Key Terms

biotherapeutics, metabolic disease, semaglutide, glp-1/glp-2
4 terms
biotherapeutics medical
"a clinical-stage biotherapeutics company focused on the oral delivery of biologics"
Biotherapeutics are medicines made from living cells or biological molecules—such as proteins, antibodies, vaccines, or engineered cells and genes—designed to prevent, treat, or cure disease by working with the body’s natural systems. They matter to investors because they can offer groundbreaking, high-value treatments but also come with higher development, manufacturing and regulatory complexity, so their commercial success can drive large stock moves like a breakthrough product or a failed trial.
metabolic disease medical
"including extensive expertise in obesity and metabolic disease."
A metabolic disease is a disorder that disrupts the body’s normal chemical processes for turning food into energy and maintaining balance, like when an engine or fuel system in a car isn’t working right. Investors care because these conditions drive demand for diagnostics, medicines, devices and long‑term care, shape regulatory and reimbursement decisions, and create predictable market opportunities or costs that affect company revenue and research priorities.
semaglutide medical
"preclinical semaglutide and GLP-1/GLP-2 data Rani announced last year"
Semaglutide is a medication originally developed to help manage blood sugar levels in people with diabetes, but it also promotes weight loss. It works by mimicking a natural hormone that helps control appetite and insulin release. For investors, its potential to influence healthcare and weight management markets makes it a significant product in the pharmaceutical industry.
glp-1/glp-2 medical
"preclinical semaglutide and GLP-1/GLP-2 data Rani announced last year"
GLP-1 and GLP-2 are naturally occurring gut hormones that help control digestion, appetite and blood sugar; drugmakers mimic them with medicines that can lower blood sugar, reduce appetite or support gut health. For investors, they matter because drugs targeting these hormones have large commercial potential and can reshape a company’s revenue and regulatory risk—think of them as a new class of tools that can change market winners and losers.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SAN JOSE, Calif., March 25, 2026 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. (“Rani Therapeutics” or “Rani”) (Nasdaq: RANI), a clinical-stage biotherapeutics company focused on the oral delivery of biologics and drugs, today announced the appointment of Jesper Høiland as Head of Strategy. Mr. Høiland has served as a strategic adviser to the company since 2023 and brings more than 30 years of global pharmaceutical leadership experience, including extensive expertise in obesity and metabolic disease.

“Jesper is a highly respected leader with a rare combination of strategic insight and deep commercial experience, and we are thrilled to welcome him as Head of Strategy,” said Talat Imran, Chief Executive Officer of Rani. “As we continue to expand our pipeline and evaluate new opportunities for the RaniPill® platform, Jesper will play a critical role in helping us prioritize the most impactful programs and align our strategy with areas of greatest clinical and market potential. His experience across global organizations and therapeutic areas, along with his strong industry relationships, will be invaluable as we advance our partnering strategy and continue to build a differentiated pipeline.”

In this newly created adviser role, Mr. Høiland will be responsible for shaping Rani’s corporate and pipeline strategy, including prioritization of internal programs, evaluation of new therapeutic opportunities, and support of the company’s partnering and business development efforts. He will work closely with the executive team to align development decisions with long-term strategic and market considerations.

Mr. Høiland brings more than three decades of experience in global pharmaceutical leadership, with a proven track record of shaping strategy, building organizations, and guiding the successful development and commercialization of innovative therapies. Most recently, he served as Global Commercial Officer at Ascendis Pharma, where he oversaw worldwide commercial strategy across established and emerging markets. Prior to Ascendis, he served as President and Chief Executive Officer of Radius Health. Earlier in his career, he served as President and Executive Vice President of Novo Nordisk’s U.S. operations, where he led key launches and commercial strategy across the company’s metabolic portfolio.

Over the course of his career, Mr. Høiland has contributed to the development and commercialization of multiple leading therapies, including Novo Nordisk’s insulin analog portfolio and Tresiba®, as well as Tymlos® and Skytrofa®, providing him with deep insight into the full lifecycle of innovative medicines from development through market adoption.

“What attracted me to Rani is the strength of its platform and the breadth of opportunity it creates across multiple therapeutic areas,” said Mr. Høiland. “The ability to deliver biologics orally has the potential to reshape treatment paradigms, and I believe Rani is uniquely positioned to capitalize on that opportunity. In particular, I was extremely impressed by the preclinical semaglutide and GLP-1/GLP-2 data Rani announced last year and how well Rani is positioned in the obesity space. My focus will be on helping the company prioritize the right programs, identifying the most valuable opportunities for the platform, and supporting strategic partnerships that can bring these therapies to patients globally. I look forward to working with the team as Rani continues to advance its pipeline and execute on its long-term strategy.”

About Rani Therapeutics
Rani Therapeutics is a clinical-stage biotherapeutics company focused on advancing technologies to enable the development of orally administered biologics and drugs. Rani has developed the RaniPill® capsule, a novel, proprietary and patented platform technology, intended to replace subcutaneous injection or intravenous infusion of biologics and drugs with oral dosing. Rani has successfully conducted several preclinical and clinical studies to evaluate safety, tolerability and bioavailability using RaniPill® capsule technology.

Forward-Looking Statements
Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements regarding, among other things, Rani’s ability to advance its clinical pipeline, the potential for the RaniPill® platform, the identification and prioritization of pipeline opportunities, the potential for future partnerships, and the expected benefits of oral biologic therapies. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as “potential,” “will,” “believe,” “look forward” and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Rani’s current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, including, without limitation, risks and uncertainties associated with Rani’s business and those described in Rani’s filings with the Securities and Exchange Commission, including Rani’s Annual Report on Form 10-K for the year ended December 31, 2025, and subsequent filings and reports by Rani. All forward-looking statements contained in this press release speak only as of the date on which they were made. Rani undertakes no obligation to update such statements to reflect events or circumstances that occur after the date on which they were made, except as required by law.

Investor Contact:
investors@ranitherapeutics.com
Media Contact:
media@ranitherapeutics.com


FAQ

Who is Jesper Høiland and what role did RANI appoint him to on March 25, 2026?

Jesper Høiland was appointed Head of Strategy at RANI on March 25, 2026. According to the company, he previously served as a strategic adviser since 2023 and brings over 30 years of global pharmaceutical leadership and commercial experience.

What responsibilities will Jesper Høiland have as Head of Strategy at RANI?

Høiland will shape corporate and pipeline strategy and prioritize programs at RANI. According to the company, responsibilities include evaluating new therapeutic opportunities and supporting partnering and business development for the RaniPill platform.

How does Jesper Høiland’s background relate to RANI’s focus on obesity and metabolic disease?

Høiland has deep commercial experience in metabolic therapies, including work at Novo Nordisk and launches like Tresiba. According to the company, his expertise is expected to help prioritize obesity-related programs and market strategies for the RaniPill platform.

What prior roles did Jesper Høiland hold before joining RANI as Head of Strategy?

Høiland served as Global Commercial Officer at Ascendis Pharma and was CEO of Radius Health, plus senior roles at Novo Nordisk. According to the company, these roles included leading launches and global commercial strategy across metabolic portfolios.

Will Jesper Høiland influence RANI’s partnering and business development efforts?

Yes, Høiland will support and advance RANI’s partnering strategy. According to the company, he will leverage industry relationships to identify strategic partnerships and align development decisions with long-term market considerations for the RaniPill platform.

Does Jesper Høiland’s appointment indicate any immediate changes to RANI’s pipeline priorities?

The appointment signals a focus on prioritization but does not announce specific program changes. According to the company, Høiland’s role is to help prioritize internal programs and evaluate opportunities across therapeutic areas for the RaniPill platform.