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Seer Announces CFO Transition

Seer will see longtime finance leader David Horn depart and FP&A head Charles Endweiss assume key financial officer roles on October 1, 2026.

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(Very Positive)
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Seer (SEER) announced a leadership change as President, Chief Financial Officer and Treasurer David Horn will depart the company effective October 1, 2026 to join a private company.

On the same date, Vice President of Financial Planning & Analysis Charles Endweiss will become Treasurer, principal financial officer and principal accounting officer. Seer’s CEO highlighted Horn’s six-year tenure and described Endweiss as a long-time finance leader with deep knowledge of the business.

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Positive

  • Internal successor Charles Endweiss named as principal financial and accounting officer effective October 1, 2026
  • Leadership continuity supported by Endweiss’s nearly five years in Seer’s finance organization

Negative

  • President, CFO and Treasurer David Horn departing effective October 1, 2026 after more than six years in leadership

Market Context

Before publication, SEER closed at $1.86 after a 3.12% decline; the CFO transition was announced aga...
Analysis

Before publication, SEER closed at $1.86 after a 3.12% decline; the CFO transition was announced against that pre-existing market position, not a measured post-headline reaction.

Key Figures

Transition effective date: October 1, 2026
Transition effective date
October 1, 2026
CFO departure and finance leadership appointments

Key Terms

proteomic insights, financial planning & analysis, principal financial officer, principal accounting officer
4 terms
proteomic insights technical
"the pioneer and trusted partner for deep, unbiased proteomic insights"
Proteomic insights are findings derived from proteomics—the large-scale study and measurement of proteins in a cell, tissue or fluid—showing which proteins are present, how much of each exists, and how they change under different conditions. For investors, these insights act like a detailed parts-list and status report for a biological system: they can reveal potential drug targets, biomarkers for disease diagnosis or treatment response, and evidence about whether a biotechnology program is working as intended.
financial planning & analysis financial
"has been Seer’s Vice President, Financial Planning & Analysis"
Financial planning & analysis (FP&A) is the corporate function that builds budgets and forecasts, tracks actual results against those plans, and models different business scenarios to inform decisions. For investors it matters because FP&A shapes the company’s financial guidance and reveals how management expects to grow, manage costs and use cash—think of it as the company’s navigation system that helps predict whether future targets and returns are realistic.
principal financial officer regulatory
"will serve as Treasurer, principal financial officer and principal accounting officer"
The principal financial officer is the senior executive who runs a company's financial operations: preparing and certifying financial reports, managing accounting controls, budgets and cash flow, and advising on financial strategy. Investors care about this role because its competence affects how trustworthy the company’s numbers are, how well it manages risk and capital needs, and the credibility of forecasts—like the chief navigator steering a firm's financial course.
principal accounting officer regulatory
"principal financial officer and principal accounting officer, effective October 1, 2026"
The Principal Accounting Officer is the person responsible for making sure a company's financial records are accurate and follow the rules. They play a key role in preparing financial reports that show how well the company is doing. This helps investors, managers, and regulators trust the company's financial information.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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REDWOOD CITY, Calif., Sept. 21, 2026 (GLOBE NEWSWIRE) -- Seer, Inc. (Nasdaq: SEER) (“Seer” or the “Company”), the pioneer and trusted partner for deep, unbiased proteomic insights, today announced that David Horn, the Company’s President, Chief Financial Officer and Treasurer, will depart Seer effective October 1, 2026, to pursue a new opportunity at a private company.

Charles Endweiss, who has been Seer’s Vice President, Financial Planning & Analysis, will serve as Treasurer, principal financial officer and principal accounting officer, effective October 1, 2026.

“David has been an important member of Seer’s leadership team for more than six years, helping guide the Company through a pivotal period,” said Omid Farokhzad, M.D., Chair and Chief Executive Officer of Seer. “We are grateful for David’s many contributions and wish him all the best in his next chapter.”

Dr. Farokhzad added, “Charles has been a trusted member of Seer’s finance organization for nearly five years and brings the financial expertise, leadership and deep understanding of our business that are critical to our continued progress. We are confident he will play an important role in continuing our efforts to position Seer for long-term success.”

“It has been a privilege to work alongside Omid and the entire Seer team over the past six years,” said Mr. Horn. “I am proud of what we have accomplished together and remain confident in the team, Seer’s differentiated technology and the opportunity ahead for the Company. I have worked closely with Charles Endweiss and am confident he will be a strong steward of the finance team. I look forward to following the Company’s continued success.”

About Charles Endweiss
Charles Endweiss, age 49, has served as the Company’s Vice President, Financial Planning & Analysis since January 2021. Prior to joining the Company, Mr. Endweiss served as Head of Business Operations, Oral Health at Carbon, a provider of end-to-end digital 3D printing and manufacturing platform, from August 2017 to January 2021. Earlier in his career, Mr. Endweiss held a range of accounting, finance, and business operations positions at various technology companies. He holds a B.A. in Business from the University of Illinois, Urbana-Champaign and an M.B.A. from Santa Clara University.

About Seer, Inc.
Seer, Inc. (Nasdaq: SEER) sets the standard in deep, unbiased proteomics, delivering insights with a scale, speed, precision and reproducibility previously unattainable. Seer’s Proteograph® Product Suite integrates proprietary engineered nanoparticles, streamlined automation instrumentation, optimized consumables and advanced analytical software to overcome the limitations of traditional proteomic methods. Seer’s products are for research use only and are not intended for diagnostic procedures. For more information, visit www.seer.bio.

For more information, please email us at pr@seer.bio.

Forward Looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Such forward-looking statements are based on Seer’s beliefs and assumptions and on information currently available to it on the date of this press release. Forward-looking statements may involve known and unknown risks, uncertainties and other factors that may cause Seer’s actual results, performance, or achievements to be materially different from those expressed or implied by the forward-looking statements. These statements include but are not limited to statements relating to the transition in finance and accounting roles at the Company. These and other risks are described more fully in Seer’s filings with the Securities and Exchange Commission (“SEC”) and other documents that Seer subsequently files with the SEC from time to time. Except to the extent required by law, Seer undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Media Contact:
Patrick Schmidt
pr@seer.bio

Investor Contact:
Marissa Bych
investor@seer.bio


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What roles will Charles Endweiss assume following the CFO transition at Seer?

Effective October 1, 2026, Charles Endweiss, currently Vice President, Financial Planning & Analysis, will serve as Treasurer, principal financial officer and principal accounting officer of Seer.

When will David Horn leave Seer and why is he departing?

David Horn will depart Seer effective October 1, 2026 to pursue a new opportunity at a private company.

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