Shuttle Pharma Announces Proposed Reverse Stock Split as Part of Strategic Nasdaq Compliance Initiative

Rhea-AI Summary

Shuttle Pharmaceuticals (SHPH) has announced a proposed 25-for-1 reverse stock split to maintain Nasdaq listing compliance. The split will reduce outstanding shares from 26.2 million to approximately 1.05 million shares, pending Nasdaq approval. The action will affect all common stock, including RSU grants and warrants, with fractional shares being rounded up. Shuttle Pharma, a specialty pharmaceutical company, focuses on developing radiation sensitizers to enhance radiation therapy outcomes for cancer patients while minimizing side effects. The reverse split is positioned as a strategic move to strengthen the company's long-term capital structure while ensuring continued Nasdaq listing compliance.

Positive

• Strategic move to maintain Nasdaq listing compliance
• Strengthening of company's capital structure through share consolidation
• Simplified share structure with 25:1 reduction in outstanding shares

Negative

• Significant share consolidation indicates potential listing compliance issues
• No change in underlying market capitalization or company value
• Potential market perception concerns associated with reverse splits

GAITHERSBURG, Md., June 12, 2025 (GLOBE NEWSWIRE) -- Shuttle Pharmaceuticals Holdings, Inc. (Nasdaq: SHPH) (“Shuttle Pharma” or the “Company”), a discovery and development stage specialty pharmaceutical company focused on improving outcomes for cancer patients treated with radiation therapy (RT), announces that its Board of Directors have approved a proposed reverse stock split of its common stock at a ratio of 25-for-1. The proposed action remains subject to approval by Nasdaq and, if approved, the Company will issue a subsequent announcement disclosing the effective date.

At the effective time of the reverse stock split, every 25 shares of the Company's issued and outstanding common stock will be automatically reclassified and combined into 1 share of common stock. This will reduce the number of issued and outstanding shares of common stock from 26,210,037 shares to approximately 1,048,401 shares, without giving effect to rounding. The split will also apply to Company common stock issuable upon the exercise of the Company's outstanding RSU grants and warrants. No fractional shares will be issued; instead, any fractional entitlements will be rounded up to the next highest whole number at the participant level.

The reverse stock split is part of Shuttle’s strategic plan to maintain compliance with Nasdaq’s continued listing requirements, while also strengthening the Company’s long-term capital structure.

About Shuttle Pharmaceuticals

Shuttle Pharma is a discovery and development stage specialty pharmaceutical company focused on improving the outcomes for cancer patients treated with radiation therapy (RT). Our mission is to improve the lives of cancer patients by developing therapies that are designed to maximize the effectiveness of RT while limiting the side effects of radiation in cancer treatment. Although RT is a proven modality for treating cancers, by developing radiation sensitizers, we aim to increase cancer cure rates, prolong patient survival and improve quality of life when used as a primary treatment or in combination with surgery, chemotherapy and immunotherapy. For more information, please visit our website at www.shuttlepharma.com.

Safe Harbor Statement

Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute “forward-looking statements.” These statements include, but are not limited to, statements concerning the development of our company. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including factors discussed in the “Risk Factors” section of Shuttle Pharma’s Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on February 26, 2025, as well other SEC filings. Any forward-looking statements contained in this press release speak only as of the date hereof and, except as required by federal securities laws, Shuttle Pharmaceuticals specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.

Shuttle Pharmaceuticals
Chris Cooper
Chief Executive Officer
info@shuttlepharma.com

Investor Contacts
Lytham Partners, LLC
shph@lythampartners.com 

FAQ

What is the ratio of Shuttle Pharmaceuticals (SHPH) reverse stock split?

Shuttle Pharmaceuticals has proposed a 25-for-1 reverse stock split, meaning every 25 shares will be combined into 1 share.

How many shares will SHPH have after the reverse split?

After the reverse split, SHPH's outstanding shares will reduce from 26,210,037 to approximately 1,048,401 shares.

Why is Shuttle Pharmaceuticals doing a reverse stock split?

The reverse split is part of Shuttle's strategic plan to maintain compliance with Nasdaq's continued listing requirements and strengthen its long-term capital structure.

What happens to fractional shares in SHPH's reverse split?

No fractional shares will be issued; any fractional entitlements will be rounded up to the next highest whole number at the participant level.

When will SHPH's reverse stock split take effect?

The effective date is pending Nasdaq approval and will be announced by the company in a subsequent announcement.