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Shuttle Pharmaceuticals Announces $3.5 Million Public Offering

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Shuttle Pharmaceuticals (NASDAQ: SHPH) announced a public offering to issue 2,238,800 shares of common stock and pre-funded warrants to purchase 4,761,200 shares for aggregate gross proceeds of approximately $3.5 million.

The offering is expected to close on or about March 9, 2026, with E.F. Hutton & Co. as exclusive placement agent. The company intends to use up to $1.5 million for marketing and the remainder for working capital and general corporate purposes. The securities are being offered under an effective Form S-1 (File No. 333-293363) registration statement.

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Positive

  • Gross proceeds of approximately $3.5 million
  • Up to $1.5 million earmarked for future marketing efforts
  • Form S-1 registration effective on February 17, 2026

Negative

  • Issuance of 2,238,800 shares plus pre-funded warrants for 4,761,200 shares may cause shareholder dilution
  • Net proceeds reduced by placement agent fees and offering expenses
  • Closing is subject to customary conditions and not certain (expected on March 9, 2026)

Key Figures

Gross proceeds: $3,500,000 Common shares offered: 2,238,800 shares Pre-funded warrant shares: 4,761,200 shares +5 more
8 metrics
Gross proceeds $3,500,000 Aggregate gross proceeds from March 2026 public offering
Common shares offered 2,238,800 shares New common stock issued in March 2026 public offering
Pre-funded warrant shares 4,761,200 shares Shares underlying pre-funded warrants in March 2026 offering
Marketing allocation Up to $1.5 million Portion of this offering’s net proceeds earmarked for marketing
S-1 registered amount 2,229,300 shares Shares and pre-funded warrants registered in February 2026 S-1/A
Assumed offering price $1.57 per share Assumed price in February 2026 S-1/A registration
Estimated 2025 net loss $10.9–$12.1 million Preliminary net loss range from February 17, 2026 8-K
Working capital deficit $0.7–$0.8 million Estimated deficit as of Dec 31, 2025 per 8-K

Market Reality Check

Price: $0.9170 Vol: Volume 57,044 is 0.51x th...
low vol
$0.9170 Last Close
Volume Volume 57,044 is 0.51x the 20-day average of 111,298, showing no pre-news accumulation spike. low
Technical Shares at $0.8685 are trading below the 200-day MA of $2.96 and sit just above the 52-week low of $0.851.

Peers on Argus

SHPH was down 6.27% while only one momentum peer (RDHL) showed an intraday move,...
1 Up

SHPH was down 6.27% while only one momentum peer (RDHL) showed an intraday move, rising about 3.64%. Other close peers showed mixed, mostly modest changes, pointing to a stock-specific reaction rather than a sector-wide move.

Previous Offering Reports

1 past event · Latest: Oct 29 (Neutral)
Same Type Pattern 1 events
Date Event Sentiment Move Catalyst
Oct 29 Equity offering Neutral +0.0% Announced $4.5M public offering to fund IND-enabling and Phase I/II trials.
Pattern Detected

The prior tagged offering in October 2024 produced a 0% next-day move, suggesting historically muted immediate price response to capital raises.

Recent Company History

Over the past 18 months, Shuttle Pharmaceuticals has repeatedly tapped the capital markets while pivoting its business model. A key prior event was the October 29, 2024 offering for $4.5 million, aimed at funding IND-enabling and Phase I/II trials, which saw a 0% 24-hour price reaction. More recently, private placements and Molecule.ai-related transactions expanded the share count and shifted focus toward AI-enabled discovery. Today’s $3.5 million public offering continues this pattern of equity financing, but proceeds are now directed mainly to marketing and general corporate purposes.

Historical Comparison

+0.0% avg move · In the last year, SHPH reported one prior offering with an average 0% next-day move. Any pronounced ...
offering
+0.0%
Average Historical Move offering

In the last year, SHPH reported one prior offering with an average 0% next-day move. Any pronounced reaction to this $3.5M raise would depart from that historically flat response.

Earlier offerings, like the $4.5M raise in October 2024, targeted clinical trial funding. The current $3.5M public offering shifts proceeds toward marketing and working capital, reflecting the transition from clinical programs toward promoting the AI-driven Molecule.ai platform and supporting general operations.

Market Pulse Summary

This announcement details a $3.5 million public offering involving 2,238,800 common shares and 4,761...
Analysis

This announcement details a $3.5 million public offering involving 2,238,800 common shares and 4,761,200 pre-funded warrant shares, with up to $1.5 million earmarked for marketing and the balance for working capital. In context of a preliminary $10.9–$12.1 million 2025 net loss and a working capital deficit of $0.7–$0.8 million, the raise addresses liquidity but increases share count. Investors may watch future capital needs, Molecule.ai integration progress, and any shift in expense trends.

Key Terms

pre-funded warrants, securities purchase agreement, public offering, registration statement on form s-1, +2 more
6 terms
pre-funded warrants financial
"shares of common stock and pre-funded warrants to purchase 4,761,200 shares"
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
securities purchase agreement financial
"announced that it has entered into a securities purchase agreement with investors"
A securities purchase agreement is a written contract between a buyer and a seller outlining the terms for buying or selling financial assets such as stocks or bonds. It specifies details like the price, quantity, and conditions of the transaction, similar to a shopping list with agreed-upon terms. For investors, it provides clarity and legal protection when transferring ownership of these financial instruments.
public offering financial
"shares of common stock and pre-funded warrants ... in a public offering"
A public offering is when a company sells shares to the general public through the stock market, either by issuing new shares to raise cash or by letting existing owners sell their stakes. Think of it like a business opening its doors to many new owners at once: it can bring in money for growth but also increases the number of shares available, which can change the stock price and dilute existing ownership — key factors investors watch closely.
registration statement on form s-1 regulatory
"pursuant to a registration statement on Form S-1 (File No. 333-293363)"
A registration statement on Form S-1 is a detailed filing a company submits to the U.S. securities regulator to register new shares for public sale; it includes a plain-language prospectus, financial statements, business description and risk factors. For investors it matters because it provides the official, comprehensive blueprint of the offering — like an owner’s manual — allowing buyers to assess risks, inspect financial health and compare valuation before deciding to invest.
prospectus regulatory
"The offering of the securities is being made only by means of a prospectus"
A prospectus is a detailed document that explains a company's plans for offering new shares or investments to the public. It’s important because it provides potential investors with key information about the company’s business, risks, and how they might make money, helping them decide whether to invest. Think of it as a guidebook for understanding what you're buying into.
placement agent financial
"E.F. Hutton & Co. is acting as the exclusive placement agent for the offering"
A placement agent is a professional or firm that helps organizations raise money from investors, such as individuals, institutions, or funds. They act like matchmakers, connecting those seeking investments with the right investors and guiding the process to ensure successful funding. For investors, they can provide access to exclusive opportunities and help navigate complex fundraising efforts.

AI-generated analysis. Not financial advice.

Gaithersburg, Maryland--(Newsfile Corp. - March 6, 2026) - Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ: SHPH) ("Shuttle Pharma" or the "Company"), the owner of Molecule.ai, an artificial intelligence ("AI") driven platform for molecular discovery and early-stage drug development, today announced that it has entered into a securities purchase agreement with investors for the issuance and sale of 2,238,800 shares of common stock and pre-funded warrants to purchase 4,761,200 shares of common stock, in a public offering, for aggregate gross proceeds of approximately $3,500,000, before deducting placement agent fees and other offering expenses. The offering is expected to close on or about March 9, 2026, subject to the satisfaction of customary closing conditions.

E.F. Hutton & Co. is acting as the exclusive placement agent for the offering. The Company intends to use up to $1.5 million of the net proceeds from this offering for future marketing efforts and the remainder for working capital and general corporate purposes.

The securities described above are being offered and sold by the Company in a public offering pursuant to a registration statement on Form S-1 (File No. 333-293363) that was originally filed with the Securities and Exchange Commission (the "SEC") on February 11, 2026, and became effective on February 17, 2026. The offering of the securities is being made only by means of a prospectus that forms a part of the effective registration statement. A preliminary prospectus relating to the offering has been filed with the SEC. A final prospectus relating to, and describing the terms of, the public offering will be filed with the SEC and will be available on the SEC's website at www.sec.gov. Electronic copies of the final prospectus relating to the public offering, when available, may also be obtained by contacting E.F. Hutton & Co., at 745 Fifth Avenue, 34th Floor & PH, New York, NY 10151, by telephone at v, or by email at info@efhutton.com.

This press release shall not constitute an offer to sell or a solicitation of an offer to buy any of the securities described herein, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction.

About Shuttle Pharmaceuticals

Shuttle Pharma (NASDAQ: SHPH) owns a pharmaceutical software AI driven platform for molecular discovery and early-stage drug development. By combining modern AI techniques with structured scientific workflows, the Molecule.ai platform helps researchers explore the chemical space more efficiently, evaluate molecular ideas with greater clarity and make more informed decisions during the earliest stages of drug development.

Cautionary Note Regarding Forward-Looking Statements

Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute "forward-looking statements." These statements include, but are not limited to, statements concerning the completion of the offering. The words "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "project," "should," "target," "will," "would" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including risks related to our ability to satisfy the closing conditions related to the offering, general economic and market risks, and factors discussed in the "Risk Factors" section of Shuttle Pharma's Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on February 26, 2025, as well as other SEC filings. Any forward-looking statements contained in this press release speak only as of the date hereof and, except as required by federal securities laws, Shuttle Pharma disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/286465

FAQ

What exactly is Shuttle Pharmaceuticals (SHPH) selling in the March 6, 2026 public offering?

Shuttle Pharma is offering 2,238,800 common shares and pre-funded warrants for 4,761,200 shares. According to Shuttle Pharma, aggregate gross proceeds are approximately $3.5 million, before placement agent fees and offering expenses.

When will the SHPH public offering close and who is the placement agent?

The offering is expected to close on or about March 9, 2026, subject to customary conditions. According to Shuttle Pharma, E.F. Hutton & Co. is the exclusive placement agent for the deal.

How does Shuttle Pharma plan to use the proceeds from the SHPH offering?

The company intends to use up to $1.5 million for marketing and the remainder for working capital. According to Shuttle Pharma, remaining net proceeds will support general corporate purposes.

Are the SHPH securities being offered under an SEC registration statement?

Yes, the securities are offered under a Form S-1 registration statement (File No. 333-293363). According to Shuttle Pharma, the Form S-1 became effective on February 17, 2026.

Will the SHPH offering dilute existing shareholders and how certain is the closing?

The issuance and warrants could dilute existing shareholders if issued and exercised. According to Shuttle Pharma, the offering is expected to close on or about March 9, 2026, but is subject to customary closing conditions.
SHUTTLE PHARMACTCLS HLDGS INC

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