Shuttle Pharmaceuticals to Acquire AI Molecular Modeling and Predictive Analytics Platform

Rhea-AI Summary

Shuttle Pharmaceuticals (NASDAQ: SHPH) announced a binding term sheet to acquire substantially all assets and liabilities of 1542770 BC Ltd. ("Molecule"), a Canadian AI molecular discovery company, for a $10 million total purchase price payable in cash and Shuttle common stock.

The final cash/equity mix will be determined by Shuttle and payments are subject to performance milestones. Closing requires mutual due diligence and execution of definitive agreements with customary conditions.

The company said the acquisition aims to expand Shuttle's AI molecular modeling and predictive analytics capabilities to support its precision radiotherapy drug-discovery pipeline.

Positive

• $10 million transaction to add AI molecular modeling assets
• Adds predictive analytics tools to Shuttle's drug-discovery pipeline
• Deal structure includes equity consideration aligning incentives

Negative

• Cash/equity mix at Shuttle's sole discretion may cause dilution
• Payments tied to performance milestones create contingent obligation
• Closing subject to mutual due diligence and may not complete

Rockville, Maryland--(Newsfile Corp. - October 21, 2025) - Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ: SHPH) ("Shuttle" or the "Company") today announced that it has entered into a binding term sheet with 1542770 BC Ltd. ("Molecule"), a Canadian artificial intelligence company specializing in molecular discovery and drug development technologies.

Under the terms of the agreement, Shuttle or one of its affiliates will acquire substantially all of Molecule's assets and liabilities for a total purchase price of $10 million, payable in a combination of cash and shares of Shuttle common stock. The exact mix of cash and equity will be determined by Shuttle at its sole discretion and will be paid over time, subject to the achievement of certain performance milestones.

The parties intend to finalize one or more definitive agreements to complete the transaction, which will include customary representations, warranties, and closing conditions. The closing of the acquisition will be subject to, among other things, satisfactory completion of mutual due diligence and the execution of the final transaction documents.

"This proposed acquisition represents an important strategic step toward expanding Shuttle's technological capabilities and advancing our mission of developing precision radiotherapy solutions," said Chris Cooper, Chief Executive Officer of Shuttle Pharmaceuticals. "Molecule's AI platform offers cutting-edge tools for molecular modeling and predictive analytics that can enhance our drug discovery and development pipeline."

About Shuttle Pharmaceuticals Holdings, Inc.
Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ: SHPH) is a clinical-stage pharmaceutical company focused on improving the outcomes of cancer therapy by developing novel drugs that sensitize cancer cells to radiation therapy. The Company's mission is to advance precision medicine approaches to radiotherapy that enhance treatment efficacy and patient quality of life.

About Molecule.AI

An intelligent platform that predicts molecular properties and interactions through autonomous AI agents helping researchers, biotech teams, and pharmaceutical innovators accelerate discovery.

Website:

https://www.moleculeai.io/

Safe Harbor Statement

Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute "forward-looking statements." These statements include, but are not limited to, statements concerning the development of our company and the closing of the acquisition of the assets of Molecule. The words "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "project," "should," "target," "will," "would" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including factors discussed in the "Risk Factors" section of Shuttle's Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on February 26, 2025, as well as other SEC filings. Any forward-looking statements contained in this press release speak only as of the date hereof and, except as required by federal securities laws, Shuttle specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.

Shuttle Pharmaceuticals
Chris Cooper
Chief Executive Officer
info@shuttlepharma.com

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/271350

FAQ

What did Shuttle Pharmaceuticals announce on October 21, 2025 regarding Molecule (SHPH)?

Shuttle announced a binding term sheet to acquire substantially all assets and liabilities of Molecule for a $10 million purchase price payable in cash and Shuttle common stock.

How will Shuttle pay for the Molecule acquisition and could it dilute SHPH shareholders?

The $10 million consideration will be paid in a mix of cash and Shuttle common stock at Shuttle's discretion, which may dilute existing SHPH shareholders if equity is used.

When will the Molecule acquisition close and what conditions apply for SHPH?

Closing requires satisfactory mutual due diligence and execution of definitive agreements with customary representations, warranties, and closing conditions; timing is not specified.

What strategic benefits does the Molecule acquisition offer to Shuttle (SHPH)?

Shuttle expects Molecule's AI platform to enhance its molecular modeling and predictive analytics capabilities to support its precision radiotherapy drug-discovery efforts.

Are any payments for the Molecule deal contingent on future milestones for SHPH?

Yes, portions of the purchase price will be paid over time and are subject to achievement of certain performance milestones.