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SenesTech's Evolve™ Rodent Birth Control Proven in Urban Rodent Hotspots from Hong Kong to San Francisco

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SenesTech (NASDAQ: SNES) has reported successful results from major urban deployments of its Evolve™ Rat Birth Control solution in Hong Kong and San Francisco. The company's innovative approach combines fertility control with traditional rodenticide methods, demonstrating significant effectiveness in urban pest control.

In Hong Kong's high-density mixed-use building deployment, the company achieved dramatic reduction in rodent sightings and bait consumption within three months. Similar success was recorded in San Francisco, with notable decreases in rodent activity and new births. SenesTech is now preparing for a container-sized order from Hong Kong following these positive results.

SenesTech (NASDAQ: SNES) ha riportato risultati positivi da importanti interventi urbani con la sua soluzione Evolve™ Rat Birth Control a Hong Kong e San Francisco. L'approccio innovativo dell'azienda combina il controllo della fertilità con i metodi tradizionali di derattizzazione, dimostrando un'efficacia significativa nel controllo dei roditori in ambienti urbani.

Nel caso degli edifici a uso misto ad alta densità di Hong Kong, l'azienda ha ottenuto una drastica riduzione degli avvistamenti di roditori e del consumo di esche entro tre mesi. Successi simili sono stati registrati a San Francisco, con una notevole diminuzione dell'attività dei roditori e delle nuove nascite. SenesTech si sta ora preparando per un ordine di dimensioni container da Hong Kong in seguito a questi risultati positivi.

SenesTech (NASDAQ: SNES) ha informado resultados exitosos de importantes despliegues urbanos de su solución Evolve™ Rat Birth Control en Hong Kong y San Francisco. El enfoque innovador de la compañía combina el control de la fertilidad con métodos tradicionales de rodenticidas, demostrando una efectividad significativa en el control de plagas urbanas.

En el despliegue en edificios de uso mixto de alta densidad en Hong Kong, la compañía logró una reducción drástica en avistamientos de roedores y consumo de cebos en tres meses. Se registró un éxito similar en San Francisco, con notables disminuciones en la actividad de roedores y nacimientos. SenesTech ahora se prepara para un pedido de tamaño contenedor desde Hong Kong tras estos resultados positivos.

SenesTech (NASDAQ: SNES)는 홍콩과 샌프란시스코에서 자사의 Evolve™ Rat Birth Control 솔루션을 대규모 도시 배치한 결과 성공적인 성과를 보고했습니다. 이 회사의 혁신적인 접근법은 전통적인 쥐약 방법과 생식 조절을 결합하여 도시 해충 관리에 있어 상당한 효과를 입증했습니다.

홍콩의 고밀도 복합용도 건물 배치에서는 3개월 이내에 설치류 목격과 미끼 소비가 크게 감소하는 성과를 거두었습니다. 샌프란시스코에서도 설치류 활동과 새끼 출산이 눈에 띄게 줄어드는 유사한 성공을 기록했습니다. SenesTech는 이러한 긍정적인 결과를 바탕으로 홍콩에서 컨테이너 규모 주문을 준비 중입니다.

SenesTech (NASDAQ : SNES) a annoncé des résultats concluants issus de déploiements majeurs en milieu urbain de sa solution Evolve™ Rat Birth Control à Hong Kong et San Francisco. L'approche innovante de l'entreprise combine le contrôle de la fertilité avec des méthodes traditionnelles de rodenticides, démontrant une efficacité significative dans la lutte contre les nuisibles urbains.

Lors du déploiement dans des bâtiments à usage mixte à haute densité à Hong Kong, l'entreprise a obtenu une réduction spectaculaire des observations de rongeurs et de la consommation d'appâts en trois mois. Un succès similaire a été enregistré à San Francisco, avec des baisses notables de l'activité des rongeurs et des nouvelles naissances. SenesTech se prépare désormais à une commande de la taille d’un conteneur depuis Hong Kong suite à ces résultats positifs.

SenesTech (NASDAQ: SNES) hat erfolgreiche Ergebnisse aus groß angelegten städtischen Einsätzen seiner Evolve™ Rat Birth Control-Lösung in Hongkong und San Francisco gemeldet. Der innovative Ansatz des Unternehmens kombiniert Fertilitätskontrolle mit traditionellen Rodentizid-Methoden und zeigt eine signifikante Wirksamkeit bei der Schädlingsbekämpfung in urbanen Gebieten.

Bei Einsätzen in hochdichten, gemischt genutzten Gebäuden in Hongkong erzielte das Unternehmen innerhalb von drei Monaten eine deutliche Reduktion von Ratten-Sichtungen und Köderverbrauch. Ähnliche Erfolge wurden in San Francisco verzeichnet, mit bemerkenswerten Rückgängen bei der Rattenaktivität und Neugeburten. SenesTech bereitet nun eine bestellung in Containergröße aus Hongkong vor, basierend auf diesen positiven Ergebnissen.

Positive
  • Successful deployment results in both Hong Kong and San Francisco markets
  • Secured container-sized order from Hong Kong for expansion
  • Reduced overall poison usage while maintaining effectiveness
  • Solution aligns with environmental regulations and public demand for humane pest control
Negative
  • None.

Insights

SenesTech demonstrates Evolve's effectiveness as a fertility control solution for urban rodent infestations, with promising commercial traction in global markets.

SenesTech's announcement provides compelling evidence that their fertility control approach is gaining meaningful traction in the urban pest management sector. The results from Hong Kong and San Francisco demonstrate a significant advancement in integrated pest management (IPM) strategy by combining Evolve™ with traditional rodenticides. This dual approach addresses both immediate control needs through poison baiting and long-term population suppression through fertility control.

What makes these deployments particularly noteworthy is the demonstrated effectiveness in high-challenge environments that have historically frustrated traditional control methods. In the Hong Kong deployment, three key metrics showed success: reduced sightings, declining bait consumption, and absence of new litters - breaking the reinfestation cycle that plagues urban environments.

The mention of a container-sized order from Hong Kong signals substantial commercial validation. In pest management, successful field demonstrations typically precede significant adoption, as professionals are notoriously cautious about new methodologies. This order suggests a transition from trial to full implementation.

From a technical perspective, Evolve's approach is particularly valuable in dense urban centers where rodents' rapid reproductive capabilities (a female rat can produce up to 50 offspring annually) have historically outpaced poisoning efforts. By addressing reproduction while maintaining traditional control measures, SenesTech is targeting a persistent gap in urban IPM programs.

This announcement indicates SenesTech is positioning itself at the intersection of regulatory trends toward reduced poison use and the persistent demand for effective rodent control solutions in global urban centers.

Pallet and Container Orders Expected for Resupply and Expansion

SURPRISE, Ariz., June 26, 2025 /PRNewswire/ -- SenesTech, Inc. (NASDAQ: SNES, "SenesTech" or the "Company"), a leader in fertility control for managing animal pest populations, today announced compelling results from two major urban deployments — one in Hong Kong and one in San Francisco — showing how pairing Evolve™ Rat Birth Control with traditional poison bait stations delivers faster, more sustainable rodent control where it's needed most.

Global Cities Face Persistent Rodent Pressure
Urban centers worldwide face constant rodent challenges due to dense infrastructure, hard-to-access breeding sites, and abundant food sources. Even the most aggressive traditional rodenticide programs often fall short over time, as rodents adapt to poisons and continue to reproduce unchecked.

A Breakthrough: Combining Fertility Control with Traditional Rodenticides
In both Hong Kong and San Francisco, pest management teams implemented a novel integrated strategy: deploying Evolve's palatable soft bait alongside conventional rodenticide blocks within standard bait stations across infested buildings and surrounding areas.

This hybrid approach tackles two critical issues simultaneously:

  • Immediate population knockdown via targeted poison baiting
  • Long-term population suppression by disrupting rodent reproduction cycles with fertility control

In Hong Kong, this method was applied in a high-density mixed-use building with persistent rodent activity. Within three months, sightings fell dramatically, bait consumption declined as the population shrank, and no new litters were detected — breaking the cycle of reinfestation that had frustrated property managers for years.

Further details on this study can be read here.

In San Francisco, an urban deployment in a heavily trafficked neighborhood known for recurring infestations achieved similar success: a clear reduction in visible rodent activity, less poison used overall, and a measurable drop in new rodent births.

A New Industry Standard for Sustainable Urban IPM
"These successes prove that fertility control isn't just an idea — it's a practical tool that helps pest professionals get ahead of chronic infestations faster and with less rodenticide. Deploying Evolve alongside bait blocks strengthens any IPM program. Cities worldwide can benefit from this smarter, more sustainable approach," said Joel Fruendt, CEO of SenesTech. "These kinds of validating results are also what trigger rapid expansion – we are currently preparing for a container-sized order from Hong Kong, for example."

Delivering Value to Investors and Operators
Fertility control solutions like Evolve align with changing environmental regulations and public demand for humane, low-toxicity pest management. For pest control professionals and property owners, this means improved outcomes, new service offerings, and better ROI from each deployment. For investors, it signals a rapidly growing global market for next-generation rodent control solutions that complement and enhance traditional tools.

About SenesTech
We are committed to improving the health of the world by humanely managing animal pest populations through our expertise in fertility control. We invented ContraPest®, the only U.S. EPA-registered contraceptive for male and female rats, as well as Evolve™ Rat and Evolve™ Mouse, EPA-designated minimum risk contraceptives for rodents, reflecting our mission to provide products that are proactive, safe and sustainable. ContraPest and Evolve fit seamlessly into all integrated pest management programs, significantly improving the overall goal of effective pest management. We strive for clean cities, efficient businesses and happy households – with a product designed to be humane, effective and sustainable.

For more information visit https://senestech.com/.

Safe Harbor Statement
This press release contains "forward-looking statements" within the meaning of federal securities laws, and we intend that such forward-looking statements be subject to the safe harbor created thereby. Such forward-looking statements include, among others, our belief that pairing Evolve with traditional poison bait stations delivers faster, more sustainable rodent control where it's needed most; our belief that fertility control is a practical tool that helps pest professionals get ahead of chronic infestations faster and with less rodenticide; our belief that deploying Evolve alongside bait blocks strengthens any IPM program; our belief that cities worldwide can benefit from this smarter, more sustainable approach; our belief that fertility control solutions like Evolve align with changing environmental regulations and public demand for humane, low-toxicity pest management, meaning improved outcomes, new service offerings, and better ROI from each deployment for pest control professionals and property owners, and signaling to investors a rapidly growing global market for next-generation rodent control solutions that complement and enhance traditional tools. Forward-looking statements may describe future expectations, plans, results or strategies and are often, but not always, made through the use of words such as "believe," "may," "future," "plan," "will," "should," "expect," "anticipate," "eventually," "project," "estimate," "continuing," "intend" and similar words or phrases. You are cautioned that such statements are subject to risks, uncertainties and other factors that could cause actual results to differ materially from those reflected by such forward-looking statements. Such factors include, among others, the successful commercialization of our products, market acceptance of our products, regulatory approval and regulation of our products and other factors and risks identified from time to time in our filings with the Securities and Exchange Commission, including our Annual Report on Form 10-K for the fiscal year ended December 31, 2024. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. Except as required by law, we do not undertake any obligation to publicly update any forward-looking statements, whether as a result of the receipt of new information, the occurrence of future events or otherwise.

Contact Information:
Investors:
Robert Blum, Lytham Partners, LLC
(602) 889-9700
senestech@lythampartners.com

Marketing:
Rochelle Paulet, Director of Marketing, SenesTech, Inc.
(928) 779-4143 x814

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/senestechs-evolve-rodent-birth-control-proven-in-urban-rodent-hotspots-from-hong-kong-to-san-francisco-302491716.html

SOURCE SenesTech, Inc.

FAQ

What results did SenesTech (SNES) achieve with Evolve™ Rat Birth Control in Hong Kong?

In Hong Kong, SenesTech's Evolve™ achieved dramatic reduction in rodent sightings and bait consumption within three months, with no new litter detection in a high-density mixed-use building.

How does SenesTech's Evolve™ pest control solution work?

Evolve™ combines traditional rodenticide blocks with fertility control soft bait, delivering both immediate population knockdown and long-term population suppression by disrupting rodent reproduction cycles.

What new orders has SenesTech (SNES) secured from the Hong Kong market?

Following successful deployment results, SenesTech is preparing for a container-sized order from Hong Kong for resupply and expansion.

How does SenesTech's Evolve™ align with environmental regulations?

Evolve™ aligns with environmental regulations by offering a humane, low-toxicity pest management solution that reduces overall poison usage while maintaining effectiveness.

What were the results of SenesTech's Evolve™ deployment in San Francisco?

In San Francisco, the deployment resulted in reduced visible rodent activity, decreased poison usage, and a measurable drop in new rodent births in a heavily trafficked neighborhood.
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