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Tectonic Therapeutic to Participate in December Investor Conferences

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Tectonic Therapeutic (NASDAQ: TECX) announced management will participate in two investor conferences in December 2025. Key events: a fireside chat at the Piper Sandler 37th Annual Healthcare Conference on December 2, 2025 at 3:30 PM ET in New York with Alise Reicin, MD, President and CEO, and one-on-one investor meetings at the Evercore 8th Annual Healthcare Conference on December 3, 2025 in Miami.

The Piper Sandler session will be webcast and available under the company’s Investors “Events & Presentations” page at www.tectonictx.com, with a replay accessible for approximately 90 days. Investors should contact their Piper Sandler or Evercore representatives to request one-on-one meetings.

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Positive

  • None.

Negative

  • None.

News Market Reaction

-4.52%
8 alerts
-4.52% News Effect
-2.4% Trough in 10 min
-$17M Valuation Impact
$358M Market Cap
0.3x Rel. Volume

On the day this news was published, TECX declined 4.52%, reflecting a moderate negative market reaction. Argus tracked a trough of -2.4% from its starting point during tracking. Our momentum scanner triggered 8 alerts that day, indicating moderate trading interest and price volatility. This price movement removed approximately $17M from the company's valuation, bringing the market cap to $358M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Piper Sandler date: December 2, 2025 Piper Sandler time: 3:30 PM EST Evercore date: December 3, 2025 +1 more
4 metrics
Piper Sandler date December 2, 2025 Piper Sandler 37th Annual Healthcare Conference fireside chat
Piper Sandler time 3:30 PM EST Scheduled start time of the fireside chat
Evercore date December 3, 2025 Evercore 8th Annual Healthcare Conference investor meetings
Webcast replay window 90 days Duration replay will remain available on company website

Market Reality Check

Price: $24.83 Vol: Volume 217,554 vs 20-day ...
low vol
$24.83 Last Close
Volume Volume 217,554 vs 20-day average 331,173 (relative volume 0.66) ahead of the conferences. low
Technical Pre-news, shares were trading above the 200-day MA (MA200 20.13), after a 2.31% daily gain.

Peers on Argus

Peer biotech names showed mixed moves, with ASMB, CTNM, DRUG and IMRX modestly h...
1 Down

Peer biotech names showed mixed moves, with ASMB, CTNM, DRUG and IMRX modestly higher while MBX declined 1.86%. Only CTNM appeared in the momentum scanner, moving down, suggesting TECX’s setup is more stock-specific than sector-driven.

Historical Context

5 past events · Latest: Dec 01 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Dec 01 Investor conferences Positive -4.5% Announced participation in two December 2025 healthcare investor conferences.
Nov 06 Earnings and pipeline Positive +15.5% Reported Q3 2025 results, strong cash position and positive TX45 data.
Oct 29 Clinical data update Positive +4.1% Released positive Phase 1b Part B hemodynamic data for TX45 in PH-HFrEF.
Aug 28 Investor conferences Positive -3.7% Announced participation in multiple September 2025 healthcare investor conferences.
Aug 07 Earnings and pipeline Positive +1.8% Reported Q2 2025 results and detailed TX45 and TX2100 development plans.
Pattern Detected

Operational and clinical milestones (earnings with data, trial readouts) have generally coincided with positive moves, while simple conference-participation announcements have seen negative next-day reactions.

Recent Company History

Over the last several months, Tectonic reported multiple clinical and financial milestones. Positive TX45 Phase 1b data and strong cash balances in Q2 and Q3 2025 earnings on Aug 7 and Nov 6 were followed by gains of 1.78% and 15.51%. The TX45 Phase 1b Part B topline readout on Oct 29 also saw a 4.14% rise. In contrast, conference-focused releases on Aug 28 and Dec 1 were followed by -3.73% and -4.52% moves, indicating a pattern of weaker reactions to non-clinical, non-financial news.

Regulatory & Risk Context

Active S-3 Shelf
Shelf Active
Active S-3 Shelf Registration 2025-07-07

The company has an effective Form S-3 shelf registration dated Jul 07, 2025, expiring Jul 07, 2028, with 0 recorded usages so far. This provides a framework for potential future securities offerings without indicating any specific timing or size.

Market Pulse Summary

This announcement highlighted Tectonic’s investor-relations push via a Piper Sandler fireside chat o...
Analysis

This announcement highlighted Tectonic’s investor-relations push via a Piper Sandler fireside chat on December 2, 2025 and Evercore meetings on December 3, 2025, with a webcast replay available for 90 days. Recent history showed stronger stock reactions to clinical and earnings catalysts than to conference notices. With an effective S-3 shelf filed on Jul 07, 2025, investors may monitor future capital-raising activity alongside upcoming TX45 and TX2100 milestones when assessing the company’s trajectory.

Key Terms

G-protein coupled receptors, GPCRs, webcast
3 terms
G-protein coupled receptors medical
"proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs)"
Cell-surface proteins that detect outside signals — such as hormones, neurotransmitters or sensory cues — and translate them into internal actions that change how a cell behaves, like a doorbell that triggers different responses inside a house. They are prime drug targets because tweaking these receptors can alter important biological processes; successful drugs that activate or block them often drive clinical advances, approvals and significant revenue for pharmaceutical portfolios, so their status matters to investors.
GPCRs medical
"proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs)"
G protein-coupled receptors (GPCRs) are proteins on cell surfaces that act like antennae or light switches, sensing signals from hormones, neurotransmitters, or drugs and turning those signals into actions inside the cell. They matter to investors because they are one of the largest drug target families: therapies that modulate GPCRs can become profitable medicines, drive clinical trial value, influence patent portfolios, and affect regulatory outcomes.
webcast technical
"The live fireside chat can also be accessed under “Events & Presentations”"
A webcast is a live or recorded online event where people watch or listen to presentations, announcements, or performances through the internet. It’s like a TV broadcast but over the internet, allowing viewers from anywhere to tune in in real time or later. Webcasts are important because they let companies share information quickly and widely with audiences around the world.

AI-generated analysis. Not financial advice.

WATERTOWN, Mass., Dec. 01, 2025 (GLOBE NEWSWIRE) -- Tectonic Therapeutic, Inc. (NASDAQ: TECX) (“Tectonic”), a clinical stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs), today announced that company management will participate in two upcoming investor conferences taking place in December 2025.

Piper Sandler 37th Annual Healthcare Conference

Date:
Time:
Location:
Format:
Presenters:
Webcast:
December 2, 2025
3:30 PM EST
New York, NY
Fireside Chat
Alise Reicin, MD, President and Chief Executive Officer
Link


Evercore 8
th Annual Healthcare Conference

Date:
Location:
Format:
December 3, 2025
Miami, FL
Investor Meetings


The live fireside chat can also be accessed under “Events & Presentations” on the Investors section of the Tectonic website at www.tectonictx.com. A replay of the webcast will be available on the Company’s website for approximately 90 days.

The Tectonic management team will host one-on-one meetings during the two conferences. Interested investors should contact their Piper Sandler and Evercore representatives to schedule meetings.

About Tectonic
Tectonic Therapeutic is a clinical-stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of GPCRs. Leveraging its proprietary technology platform called GEODe™ (GPCRs Engineered for Optimal Discovery), Tectonic is focused on developing biologic medicines that overcome the existing challenges of GPCR-targeted drug discovery and harness the human body to modify the course of disease. Tectonic focuses on areas of significant unmet medical need, often where therapeutic options are poor or nonexistent, as these are areas where new medicines have the potential to improve patient quality of life. Tectonic is headquartered in Watertown, Massachusetts. For more information, please visit www.tectonictx.com and follow us on LinkedIn.



Contacts:

Investors:
Dan Ferry
LifeSci Advisors
(617) 430-7576
daniel@lifesciadvisors.com

Media:
Kathryn Morris
The Yates Network
(914) 204-6412
kathryn@theyatesnetwork.com

FAQ

When will Tectonic Therapeutic (TECX) present at the Piper Sandler Healthcare Conference in December 2025?

Tectonic will hold a fireside chat on December 2, 2025 at 3:30 PM ET in New York.

Who will represent Tectonic Therapeutic (TECX) at the December 2, 2025 Piper Sandler fireside chat?

Alise Reicin, MD, President and Chief Executive Officer, will participate in the fireside chat.

Will the Piper Sandler fireside chat for Tectonic Therapeutic (TECX) be available online and for how long?

Yes; the live webcast is on the company Investors “Events & Presentations” page and a replay will be available for about 90 days.

When and where will Tectonic Therapeutic (TECX) hold investor meetings at Evercore in December 2025?

Tectonic management will host one-on-one investor meetings at the Evercore conference on December 3, 2025 in Miami.

How can investors schedule one-on-one meetings with Tectonic Therapeutic (TECX) at the December 2025 conferences?

Interested investors should contact their Piper Sandler or Evercore representatives to schedule meetings.
Tectonic Therapeutic Inc

NASDAQ:TECX

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TECX Stock Data

456.12M
11.05M
38.21%
65.05%
13.82%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
WATERTOWN