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Tiziana Life Sciences to Present at Jefferies Global Healthcare Conference

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Tiziana Life Sciences (Nasdaq: TLSA) said its senior leadership will present a corporate overview at the Jefferies London Healthcare Conference on Wednesday, November 19, 2025. The presentation is scheduled for 12:30 p.m.–12:55 p.m. GMT and will run 25 minutes.

CEO Ivor Elrifi and COO/CFO Keeren Shah will discuss the company’s pipeline and recent clinical milestones, including an update on lead candidate intranasal foralumab, a fully human anti‑CD3 monoclonal antibody in clinical development for neurodegenerative diseases such as non‑active SPMS, Alzheimer’s disease, MSA, and ALS. Management will be available for one‑on‑one meetings via the conference portal or investor relations.

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News Market Reaction – TLSA

-7.30%
1 alert
-7.30% News Effect
-$16M Valuation Impact
$206M Market Cap
0.3x Rel. Volume

On the day this news was published, TLSA declined 7.30%, reflecting a notable negative market reaction. This price movement removed approximately $16M from the company's valuation, bringing the market cap to $206M at that time.

Data tracked by StockTitan Argus on the day of publication.

BOSTON, Nov. 13, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announced that its senior leadership team will present at the prestigious Jefferies London Healthcare Conference.

Chief Executive Officer Ivor Elrifi and Chief Operating Officer/Chief Financial Officer Keeren Shah will deliver a corporate overview highlighting the Company’s innovative pipeline and recent clinical milestones. The session will include an update on the lead candidate foralumab, the only fully human anti-CD3 monoclonal antibody in clinical development administered intranasally for neurodegenerative diseases such as non-active secondary progressive multiple sclerosis (SPMS), Alzheimer’s disease (AD), multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS).

The Jefferies London Healthcare Conference is one of Europe’s premier investor forums, attracting leading global healthcare companies, institutional investors, and industry thought leaders. Tiziana’s participation underscores its growing visibility within the biotechnology investment community and its commitment to advancing transformative therapies for patients with high unmet medical needs.

Presentation Details
Event: Jefferies London Healthcare Conference
Date: Wednesday, November 19, 2025
Time: 12:30 p.m. – 12:55 p.m. GMT (25-minute presentation)
Location: London, UK
Presenters:

  • Ivor Elrifi, Chief Executive Officer
  • Keeren Shah, Chief Operating Officer and Chief Financial Officer

Management will also be available for one-on-one meetings throughout the conference. Interested parties may request meetings through the Jefferies conference portal or by contacting Tiziana’s investor relations team.

About Foralumab

Foralumab, a fully human anti-CD3 monoclonal antibody, is a biological drug candidate that has been shown to stimulate T regulatory cells when dosed intranasally. At present, 14 patients with Non-Active Secondary Progressive Multiple Sclerosis (na-SPMS) have been dosed in an open-label intermediate sized Expanded Access (EA) Program (NCT06802328) with either an improvement or stability of disease seen within 6 months in all patients. In addition, intranasal foralumab is currently being studied in a Phase 2a, randomized, double-blind, placebo-controlled, multicenter, dose-ranging trial in patients with non-active secondary progressive multiple sclerosis (NCT06292923).

Foralumab is the only fully human anti-CD3 monoclonal antibody (mAb) currently in clinical development. Immunomodulation by intranasal foralumab represents a novel avenue for the treatment of neuroinflammatory and neurodegenerative human diseases.[1],[2]

About Tiziana Life Sciences

Tiziana Life Sciences is a clinical-stage biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies to enable alternative routes of immunotherapy. Tiziana’s innovative nasal approach has the potential to provide an improvement in efficacy as well as safety and tolerability compared to intravenous (IV) delivery. Tiziana’s lead candidate, intranasal foralumab, which is the only fully human anti-CD3 mAb currently in clinical development, has demonstrated a favorable safety profile and clinical response in patients in studies to date. Tiziana’s technology for alternative routes of immunotherapy has been patented with several applications pending and is expected to allow for broad pipeline applications.

For more information about Tiziana Life Sciences and its innovative pipeline of therapies, please visit www.tizianalifesciences.com.

For further inquiries:

Tiziana Life Sciences Ltd
Paul Spencer, Business Development, and Investor Relations
+44 (0) 207 495 2379
email: info@tizianalifesciences.com

[1] https://www.pnas.org/doi/10.1073/pnas.2220272120

[2] https://www.pnas.org/doi/10.1073/pnas.2309221120


FAQ

When is Tiziana Life Sciences (TLSA) presenting at the Jefferies London Healthcare Conference?

Tiziana is presenting on Wednesday, November 19, 2025 from 12:30 p.m. to 12:55 p.m. GMT.

Who will present for TLSA at the Jefferies London Healthcare Conference?

Presenters are CEO Ivor Elrifi and COO/CFO Keeren Shah.

What will TLSA discuss in its November 19, 2025 presentation?

Management will provide a corporate overview, highlight the pipeline and recent clinical milestones, and update on intranasal foralumab.

What is intranasal foralumab and which diseases is TLSA developing it for?

Intranasal foralumab is a fully human anti‑CD3 monoclonal antibody in clinical development for neurodegenerative diseases including non‑active SPMS, Alzheimer’s disease, MSA, and ALS.

How long is the TLSA presentation at the Jefferies conference on November 19, 2025?

The presentation is scheduled for 25 minutes (12:30 p.m.–12:55 p.m. GMT).

How can investors request one‑on‑one meetings with TLSA management at the Jefferies conference?

Interested parties may request meetings through the Jefferies conference portal or by contacting Tiziana’s investor relations team.
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