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Trevi Therapeutics (TRVI) Stock News

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Welcome to our dedicated page for Trevi Therapeutics news (Ticker: TRVI), a resource for investors and traders seeking the latest updates and insights on Trevi Therapeutics stock.

Trevi Therapeutics, Inc. reports news on its clinical-stage biopharmaceutical development of Haduvio, an oral extended-release formulation of nalbuphine, for chronic cough in patients with idiopathic pulmonary fibrosis, non-IPF interstitial lung disease, and refractory chronic cough. Company updates commonly cover clinical trial results and plans, FDA interactions, medical-conference presentations, intellectual property, and the investigational status of Haduvio.

Trevi also reports financing and corporate updates tied to its development strategy, including common stock offerings, quarterly financial results, cash runway commentary, and participation in healthcare investor events.

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Trevi Therapeutics (NASDAQ: TRVI) announced positive Phase 2b CORAL trial results for Haduvio in treating chronic cough in idiopathic pulmonary fibrosis (IPF) patients. The trial met its primary endpoint with significant reductions in 24-hour cough frequency across all dose groups, with the highest dose (108mg BID) achieving a -43.3% placebo-adjusted reduction. The drug demonstrated rapid efficacy at Week 2 and was well-tolerated, with similar discontinuation rates between treatment (5.6%) and placebo (5.0%) groups. Secondary endpoints showed significant improvements in cough severity and patient-reported outcomes. The company plans to meet with the FDA and initiate Phase 3 trials in first half of 2026.
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Trevi Therapeutics (NASDAQ: TRVI) has scheduled a conference call and webcast for June 2nd, 2025, at 8:30 a.m. ET to present topline results from their Phase 2b CORAL trial. The trial evaluates Haduvio (oral nalbuphine ER) for treating chronic cough in patients with idiopathic pulmonary fibrosis (IPF). The presentation will be accessible via webcast with audio and slides, and participants can join by phone at (877) 870 4263 (domestic) or (412) 317 0790 (international). A 30-day replay will be available on the company's website after the event. Haduvio is also being investigated for refractory chronic cough (RCC) treatment.
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Trevi Therapeutics (NASDAQ: TRVI), a clinical-stage biopharmaceutical company developing Haduvio™ (oral nalbuphine ER) for chronic cough treatments, announced its participation in three major conferences in June 2025. The company will present at the American Cough Conference (June 6-7) discussing RIVER trial demographics for refractory chronic cough. At the CPDD 87th Annual Scientific Meeting (June 14-18), they will present research on nalbuphine's human abuse potential. Finally, at the BIO International Convention (June 16-19), the company will deliver a corporate presentation. Key executives, including CEO Jennifer Good and other senior management, will represent Trevi at these events.

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Trevi Therapeutics (NASDAQ: TRVI) has presented additional analyses from its Phase 2a RIVER trial of Haduvio™ (oral nalbuphine ER) for refractory chronic cough (RCC). The trial met its primary endpoint with a 67% reduction in 24-hour cough frequency from baseline and 57% on a placebo-adjusted basis (p0.0001)
  • Statistically significant responder analyses across all doses at 30%, 50%, and 75% thresholds
  • Significant improvement in Leicester Cough Questionnaire at Day 21
  • Adverse events were more common during initial exposure (27mg BID) but decreased over time
  • Most discontinuations occurred in first two weeks due to CNS and GI-related adverse events
  • The company awaits Phase 2b trial results in IPF patients with chronic cough to determine future development strategy.
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    Trevi Therapeutics (NASDAQ: TRVI) reported Q1 2025 financial results and key developments for its drug candidate Haduvio. The company announced positive Phase 2a RIVER trial results showing a significant 67% reduction in 24-hour cough frequency from baseline in refractory chronic cough patients. The Phase 2b CORAL trial for IPF patients with chronic cough completed enrollment and last patient visit, with topline results expected in Q2 2025. Financially, Trevi ended Q1 with $103.3 million in cash, providing runway into Q4 2026. The company reported R&D expenses of $7.8 million (down from $8.8 million in Q1 2024) and G&A expenses of $3.7 million (up from $3.1 million), resulting in a net loss of $10.3 million compared to $10.9 million in the same period last year.
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    Trevi Therapeutics (NASDAQ: TRVI) has scheduled its Q1 2025 financial results and corporate update conference call for May 8, 2025, at 4:30 p.m. ET. The company, which is developing Haduvio™ (oral nalbuphine ER) for chronic cough treatment in patients with idiopathic pulmonary fibrosis (IPF) or refractory chronic cough (RCC), will host the event via conference call and live audio webcast. Investors can join by dialing (877) 870 4263 (domestic) or (412) 317 0790 (international). The webcast will be available through the 'Investors & News' section on Trevi's website and archived for 30 days afterward.

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    Trevi Therapeutics (Nasdaq: TRVI), developing Haduvio™ (oral nalbuphine ER) for chronic cough in patients with idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC), has announced its participation in three major investor conferences this April 2025.

    The company will present at the following events:

    • 24th Annual Needham Virtual Healthcare Conference (April 7-10) with a corporate presentation on April 7 at 11:00-11:40 a.m. ET
    • Jones Healthcare and Technology Innovation Conference (April 8-9) in Las Vegas, with a presentation on April 9 at 11:00-11:20 a.m. PT
    • Piper Sandler Spring Biopharma Symposium (April 16-17) in Boston

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    Trevi Therapeutics (NASDAQ: TRVI) reported significant progress in its clinical trials for Haduvio, a therapy for chronic cough conditions. The company announced positive topline data from Phase 2a RIVER trial showing a 57% placebo-adjusted reduction in 24-hour cough frequency for refractory chronic cough patients.

    Key developments include completed enrollment in the Phase 2b CORAL trial for IPF chronic cough patients, with topline data expected in Q2 2025, and positive sample size re-estimation outcome requiring no changes to the study. The company also reported positive results from its Human Abuse Potential study.

    Financial highlights for Q4 2024:

    • Cash position: $107.6 million, with runway into H2 2026
    • R&D expenses: $9.3 million (up from $6.5M in Q4 2023)
    • Net loss: $11.4 million (compared to $7.8M in Q4 2023)

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    Trevi Therapeutics (NASDAQ: TRVI) has scheduled its fourth quarter and year-end 2024 financial results announcement and corporate update for March 18, 2025, at 4:30 p.m. ET. The company, which is developing Haduvio™ (oral nalbuphine ER) for chronic cough treatment in patients with idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC), will host a conference call and live audio webcast.

    Participants can join via phone at (877) 870 4263 (domestic) or (412) 317 0790 (international). The webcast will be available through the 'Investors & News' section on Trevi's website, with a 30-day replay option available after the event.

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    Trevi Therapeutics (NASDAQ: TRVI) announced positive topline results from its Phase 2a RIVER trial evaluating Haduvio for refractory chronic cough (RCC). The trial met its primary endpoint with a 57% placebo-adjusted reduction in 24-hour cough frequency (p0.0001).Key findings include:

    • 67% reduction in cough frequency from baseline
    • 66% reduction in severe cough subgroup
    • 68% reduction in moderate cough subgroup
    • 84% of Haduvio patients achieved at least 30% reduction in cough frequency vs 29% for placebo

    The trial involved 66 patients in a randomized, double-blind, placebo-controlled crossover study. Significant improvements were observed as early as Day 7 at the lowest dose (27mg BID). Common side effects included constipation, nausea, somnolence, headache, dizziness, and fatigue, with no serious adverse events reported.

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    FAQ

    What is the current stock price of Trevi Therapeutics (TRVI)?

    The current stock price of Trevi Therapeutics (TRVI) is $14.21 as of June 12, 2026.

    What is the market cap of Trevi Therapeutics (TRVI)?

    The market cap of Trevi Therapeutics (TRVI) is approximately 1.9B.