Turnstone Biologics Corp. Reports Fourth Quarter and Full Year 2024 Financial Results
Rhea-AI Summary
Turnstone Biologics (Nasdaq: TSBX) reported its Q4 and full year 2024 financial results, marking significant changes in its operations. The company, previously focused on Selected TIL therapy for solid tumors, announced the discontinuation of all TIDAL-01 clinical studies in January 2025 and is now exploring strategic alternatives to maximize shareholder value.
Financial highlights show cash, cash equivalents, and short-term investments of $28.9 million as of December 31, 2024. Q4 2024 R&D expenses decreased to $8.2 million from $13.5 million in Q4 2023, while G&A expenses reduced to $3.2 million from $4.4 million year-over-year. The company's net loss improved to $12.9 million in Q4 2024 compared to $16.5 million in Q4 2023, primarily due to corporate restructuring and workforce reduction.
Positive
- Net loss improved by $3.6 million year-over-year in Q4
- Reduced R&D expenses by $5.3 million through restructuring
- Decreased G&A expenses by $1.2 million through cost-cutting measures
Negative
- Discontinuation of all TIDAL-01 clinical studies
- Company forced to explore strategic alternatives
- Significant workforce reduction implemented
- Cash position of $28.9M may limit future operations
News Market Reaction 1 Alert
On the day this news was published, TSBX declined 0.24%, reflecting a mild negative market reaction.
Data tracked by StockTitan Argus on the day of publication.
SAN DIEGO, March 28, 2025 (GLOBE NEWSWIRE) -- Turnstone Biologics Corp. (“Turnstone” or the “Company”) (Nasdaq: TSBX), a biotechnology company historically focused on the development of a differentiated approach to treat and cure patients with solid tumors by pioneering selected tumor-infiltrating lymphocyte (“Selected TIL”) therapy, today announced its financial results for the fourth quarter and full year ended December 31, 2024, and provided recent corporate updates.
Corporate Updates
In November 2024, the Company presented preclinical data on its Selected TIL therapies at the 2024 Society for Immunotherapy of Cancer (“SITC”) Annual Meeting. Turnstone also presented clinical data at the SITC TIL Symposium in a presentation titled “TIDAL-01: Enriching for a More Potent TIL Population with Selected TIL Therapy”.
In January 2025, Turnstone made the determination to discontinue all TIDAL-01 clinical studies and halted further development of the program. As a result, the Company initiated a process to explore a range of potential strategic alternatives focused on maximizing shareholder value. Turnstone continues to evaluate strategic alternatives and will provide additional updates when it is determined that further disclosure is appropriate or legally required.
Financial Highlights
Cash, Cash Equivalents and Short-Term Investments: As of December 31, 2024, cash, cash equivalents, and short-term investments were
Research and Development (“R&D”) Expenses: R&D expenses for the three months ended December 31, 2024, were
General and Administrative (“G&A”) Expenses: G&A expenses for the three months ended December 31, 2024, were
Net Loss: Net loss for the three months ended December 31, 2024, was
About Turnstone
Turnstone Biologics is a biotechnology company historically focused on the development of a differentiated approach to treat and cure patients with solid tumors by pioneering selected tumor-infiltrating lymphocyte (“Selected TIL”) therapy. For additional information about Turnstone, please visit www.turnstonebio.com.
Forward-Looking Statements
Statements contained in this press release regarding matters that may occur in the future are “forward looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including but not limited to statements in this press release regarding Turnstone’s plans to explore and evaluate a range of potential strategic alternatives focused on maximizing shareholder value. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied by such forward-looking statements. In particular, the following factors, among others, could cause results to differ materially from those expressed or implied by such forward-looking statements: Turnstone’s ability to execute its planned exploration and evaluation of strategic alternatives; and unexpected demands on Turnstone’s cash resources. For a fuller description of risks and uncertainties that could cause actual results to differ from those expressed in forward-looking statements, see Turnstone’s Annual Report on Form 10-K for the year ended December 31, 2024, to be filed with the Securities and Exchange Commission, and Turnstone’s Quarterly Reports on Form 10-Q, especially, in each case, under the caption “Risk Factors,” as well as other documents that may be filed by Turnstone from time to time with the Securities and Exchange Commission. Investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release. Turnstone undertakes no obligation to update any forward-looking statement in this press release, except as required by law.
Contact
Ahmed Aneizi
Investor Relations
Turnstone Biologics
(347) 897-5988
ahmed.aneizi@turnstonebio.com
| Condensed Consolidated Statement of Operations and Comprehensive Income (Loss) (unaudited) (In thousands, except share and per share data) | ||||||||||||||||
| Three Months Ended December 31, | Year Ended December 31, | |||||||||||||||
| 2024 | 2023 | 2024 | 2023 | |||||||||||||
| Collaboration revenue | $ | — | $ | — | $ | — | $ | 19,306 | ||||||||
| Operating expenses: | ||||||||||||||||
| Research and development | 8,160 | 13,458 | 56,104 | 60,491 | ||||||||||||
| General and administrative | 3,218 | 4,398 | 16,390 | 17,847 | ||||||||||||
| Total operating expenses | 11,378 | 17,856 | 72,494 | 78,338 | ||||||||||||
| Loss from operations | (11,378 | ) | (17,856 | ) | (72,494 | ) | (59,032 | ) | ||||||||
| Other (expense) income, net | (659 | ) | 1,241 | 1,694 | 3,546 | |||||||||||
| Net loss before income taxes | (12,037 | ) | (16,615 | ) | (70,800 | ) | (55,486 | ) | ||||||||
| (Provision) benefit for income taxes | (835 | ) | 165 | (37 | ) | 286 | ||||||||||
| Net loss | $ | (12,872 | ) | $ | (16,450 | ) | $ | (70,837 | ) | $ | (55,200 | ) | ||||
| Other comprehensive (loss) income | (6 | ) | 122 | (83 | ) | 294 | ||||||||||
| Total comprehensive loss | $ | (12,878 | ) | $ | (16,328 | ) | $ | (70,920 | ) | $ | (54,906 | ) | ||||
| Net loss attributable to common stockholders, basic and diluted | (12,872 | ) | (16,773 | ) | (70,837 | ) | (55,239 | ) | ||||||||
| Weighted-average shares of common stock outstanding, basic and diluted | 23,059,747 | 22,934,594 | 23,037,078 | 11,562,910 | ||||||||||||
| Net loss per share attributable to common stockholders, basic and diluted | $ | (0.56 | ) | $ | (0.73 | ) | $ | (3.07 | ) | $ | (4.78 | ) | ||||
| Condensed Consolidated Balance Sheet (unaudited) (In thousands) | |||||||
| December 31, 2024 | December 31, 2023 | ||||||
| (unaudited) | |||||||
| Cash and cash equivalents and short term investments | $ | 28,926 | $ | 94,777 | |||
| Total assets | 40,139 | 112,815 | |||||
| Total liabilities | 8,672 | 14,148 | |||||
| Total stockholders' deficit | 31,467 | 98,667 | |||||
FAQ
Why did Turnstone Biologics (TSBX) discontinue the TIDAL-01 clinical studies in January 2025?
What is the current cash position of Turnstone Biologics (TSBX) as of Q4 2024?
How much did Turnstone Biologics (TSBX) reduce its R&D expenses in Q4 2024?
What was TSBX's net loss in Q4 2024 compared to Q4 2023?
