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10x Genomics Reports Second Quarter 2025 Financial Results

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10x Genomics (NASDAQ: TXG) reported Q2 2025 financial results with total revenue of $172.9 million, including a $27.3 million patent litigation settlement. Excluding the settlement, revenue was $145.6 million, representing a 5% year-over-year decrease.

Key highlights include a $30 million acquisition of Scale Biosciences, improved gross margin of 72% (67% excluding license revenue), and net income of $34.5 million compared to a loss in the previous year. The company maintains a strong cash position of $447.3 million.

For Q3 2025, 10x Genomics projects revenue between $140-144 million, accounting for approximately $4 million in accelerated Chinese purchases due to potential tariff changes.

10x Genomics (NASDAQ: TXG) ha comunicato i risultati finanziari del secondo trimestre 2025 con un fatturato totale di 172,9 milioni di dollari, incluso un accordo per una controversia brevettuale di 27,3 milioni di dollari. Escludendo tale accordo, il fatturato è stato di 145,6 milioni di dollari, con una diminuzione del 5% rispetto all’anno precedente.

I punti salienti comprendono un’acquisizione da 30 milioni di dollari di Scale Biosciences, un miglioramento del margine lordo al 72% (67% escludendo i ricavi da licenze) e un utile netto di 34,5 milioni di dollari rispetto a una perdita nell’anno precedente. L’azienda mantiene una solida posizione di cassa pari a 447,3 milioni di dollari.

Per il terzo trimestre 2025, 10x Genomics prevede un fatturato compreso tra 140 e 144 milioni di dollari, includendo circa 4 milioni di dollari di acquisti anticipati dalla Cina dovuti a possibili modifiche tariffarie.

10x Genomics (NASDAQ: TXG) reportó los resultados financieros del segundo trimestre de 2025 con ingresos totales de 172,9 millones de dólares, incluyendo un acuerdo por litigio de patentes de 27,3 millones de dólares. Excluyendo este acuerdo, los ingresos fueron de 145,6 millones de dólares, lo que representa una disminución del 5% interanual.

Los aspectos destacados incluyen una adquisición de 30 millones de dólares de Scale Biosciences, una mejora en el margen bruto al 72% (67% sin contar los ingresos por licencias) y una ganancia neta de 34,5 millones de dólares en comparación con una pérdida el año anterior. La compañía mantiene una sólida posición de efectivo de 447,3 millones de dólares.

Para el tercer trimestre de 2025, 10x Genomics proyecta ingresos entre 140 y 144 millones de dólares, considerando aproximadamente 4 millones de dólares en compras anticipadas en China debido a posibles cambios arancelarios.

10x Genomics (NASDAQ: TXG)는 2025년 2분기 재무 결과를 발표했으며, 총 매출은 1억 7,290만 달러로, 이 중 2,730만 달러는 특허 소송 합의금입니다. 합의금을 제외한 매출은 1억 4,560만 달러로 전년 대비 5% 감소했습니다.

주요 내용으로는 3,000만 달러 규모의 Scale Biosciences 인수, 72%의 개선된 총이익률(라이선스 수익 제외 시 67%), 그리고 전년 손실에서 3,450만 달러의 순이익으로 전환한 점이 포함됩니다. 회사는 4억 4,730만 달러의 강력한 현금 보유고를 유지하고 있습니다.

2025년 3분기에는 잠재적인 관세 변경에 따른 중국에서의 약 400만 달러 조기 구매를 반영하여 1억 4,000만~1억 4,400만 달러의 매출을 예상하고 있습니다.

10x Genomics (NASDAQ : TXG) a publié ses résultats financiers du deuxième trimestre 2025, affichant un chiffre d’affaires total de 172,9 millions de dollars, incluant un règlement de litige sur un brevet de 27,3 millions de dollars. Hors règlement, le chiffre d’affaires s’élève à 145,6 millions de dollars, soit une baisse de 5 % par rapport à l’année précédente.

Les points clés comprennent une acquisition de 30 millions de dollars de Scale Biosciences, une marge brute améliorée à 72 % (67 % hors revenus de licences) et un bénéfice net de 34,5 millions de dollars contre une perte l’année précédente. L’entreprise conserve une solide trésorerie de 447,3 millions de dollars.

Pour le troisième trimestre 2025, 10x Genomics prévoit un chiffre d’affaires compris entre 140 et 144 millions de dollars, intégrant environ 4 millions de dollars d’achats anticipés en Chine en raison de potentielles modifications tarifaires.

10x Genomics (NASDAQ: TXG) meldete die Finanzergebnisse für das zweite Quartal 2025 mit einem Gesamtumsatz von 172,9 Millionen US-Dollar, einschließlich einer Patentstreitbeilegung in Höhe von 27,3 Millionen US-Dollar. Ohne diese Einigung betrug der Umsatz 145,6 Millionen US-Dollar, was einem Rückgang von 5 % gegenüber dem Vorjahr entspricht.

Zu den wichtigsten Highlights zählen eine 30 Millionen US-Dollar teure Übernahme von Scale Biosciences, eine verbesserte Bruttomarge von 72 % (67 % ohne Lizenzumsätze) und ein Nettogewinn von 34,5 Millionen US-Dollar im Vergleich zu einem Verlust im Vorjahr. Das Unternehmen hält eine starke Barreserve von 447,3 Millionen US-Dollar.

Für das dritte Quartal 2025 prognostiziert 10x Genomics einen Umsatz zwischen 140 und 144 Millionen US-Dollar, wobei etwa 4 Millionen US-Dollar an vorgezogenen chinesischen Käufen aufgrund möglicher Zolländerungen berücksichtigt werden.

Positive
  • Net income of $34.5 million, compared to $37.9 million loss in prior year
  • Improved gross margin to 72% from 68% year-over-year
  • Strong cash position of $447.3 million, up $20 million from previous quarter
  • Strategic acquisition of Scale Biosciences for $30 million to strengthen single cell analysis capabilities
  • Successful patent litigation settlement resulting in $27.3 million revenue
Negative
  • 5% year-over-year revenue decrease excluding litigation settlement
  • Decline in instrument revenue
  • Q3 guidance affected by $4 million pull-forward of Chinese orders due to tariff concerns
  • Continued uncertainty in funding environment

Insights

10x Genomics reports mixed Q2 results with boosted figures from litigation settlement amid challenging market conditions while making strategic acquisitions.

Looking beneath the surface of 10x Genomics' Q2 results reveals a complex picture. The headline $172.9 million revenue includes a substantial $27.3 million from a patent litigation settlement, masking the core operational revenue of $145.6 million - a 5% year-over-year decline. This core revenue weakness is primarily attributable to decreased instrument sales, suggesting labs remain cautious with capital expenditures.

The company's gross margin improvement to 72% (from 68% year-over-year) appears impressive but is largely driven by the high-margin litigation settlement. The adjusted gross margin of 67% excluding this one-time benefit provides a more accurate operational picture.

The $30 million acquisition of Scale Biosciences represents a strategic move to strengthen 10x's single-cell analysis capabilities while potentially opening more cost-sensitive market segments. This acquisition, alongside the launch of enhanced Visium HD products and the TISHUMAP partnership, demonstrates the company's continued innovation focus despite market pressures.

Cash position remains solid at $447.3 million, increasing $20 million quarter-over-quarter, providing ample runway for continued R&D investment. However, Q3 guidance of $140-144 million suggests continued headwinds, especially considering $4 million of Chinese orders were pulled forward from Q3 into Q2 due to tariff concerns.

The $40.7 million gain from litigation settlement significantly impacts operating income, which swung from a $41.7 million loss last year to $30.1 million profit this quarter. Similarly, net income of $34.5 million versus prior year's $37.9 million loss is heavily influenced by these one-time factors rather than operational improvements.

Management's commentary about "continued uncertainty in the funding environment" and focus on "disciplined execution" signals ongoing caution about market conditions for life sciences tools, particularly in academia and biotech where funding constraints persist.

PLEASANTON, Calif., Aug. 7, 2025 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, today reported financial results for the second quarter ended June 30, 2025.

Recent Updates

  • Revenue was $172.9 million for the second quarter. Excluding $27.3 million related to a patent litigation settlement, revenue was $145.6 million.
  • Ended the second quarter with cash and cash equivalents and marketable securities of $447.3 million, representing a $20 million increase over the prior quarter.
  • Entered into a definitive agreement to acquire Scale Biosciences for upfront cash and stock consideration of $30 million, plus contingent consideration that could become payable upon the achievement of certain milestones. The acquisition strengthens the company's leadership in single cell analysis with key technology that will drive innovation and expand access by enabling more powerful, affordable and scalable experiments across a broader range of applications.
  • Began shipping Visium HD 3' and HD cell segmentation, expanding the Visium portfolio's capabilities by enabling high-resolution, high-sensitivity profiling across a wider range of applications.
  • Announced a partnership with the Genome Institute of Singapore on the TISHUMAP initiative, which will leverage Xenium and AI to uncover novel biomarkers and therapeutic targets for cancer and inflammatory diseases.

"The second quarter unfolded largely as anticipated," said Serge Saxonov, Co-founder and CEO of 10x Genomics. "Amid continued uncertainty in the funding environment, we're encouraged by the resilience of our business and the dedication of our team. We're focused on disciplined execution, and remain confident in the strength of our technology, the momentum behind our platforms and the significant long-term opportunity in front of us."

Second Quarter 2025 Financial Results

Revenue was $172.9 million for the second quarter of 2025. Excluding $27.3 million related to a patent litigation settlement, revenue was $145.6 million, a 5% decrease from the corresponding period of 2024, primarily driven by a decrease in instrument revenue. This figure also reflects approximately $4.0 million of revenue that resulted from customers in China accelerating purchases from the third quarter into the second quarter in anticipation of potential tariff changes. 

Gross margin was 72% for the second quarter of 2025, as compared to 68% for the corresponding prior year period. The increase in gross margin was primarily due to higher license and royalty revenue and lower royalties and warranty costs, partially offset by an increase in inventory reserves and higher manufacturing costs. Excluding the impact of license and royalty revenue, gross margin was 67% for the second quarter of 2025.

Operating expenses were $95.0 million for the second quarter of 2025, a 35% decrease from $146.0 million for the corresponding prior year period. The decrease was primarily driven by a $40.7 million gain on settlement related to the litigation settlement.

Operating income was $30.1 million for the second quarter of 2025, as compared to operating loss of $41.7 million for the corresponding prior year period.

Net income was $34.5 million for the second quarter of 2025, as compared to a net loss of $37.9 million for the corresponding prior year period.

Cash and cash equivalents and marketable securities were $447.3 million as of June 30, 2025.

Third Quarter 2025 Revenue Guidance

10x Genomics expects third quarter 2025 revenue to be in the range of $140 million to $144 million. This guidance reflects approximately $4.0 million of revenue that resulted from customers in China accelerating purchases from the third quarter into the second quarter in anticipation of potential tariff changes.

Webcast and Conference Call Information

10x Genomics will host a conference call to discuss the second quarter 2025 financial results, business developments and outlook after market close on Thursday, August 7, 2025 at 1:30 PM Pacific Time / 4:30 PM Eastern Time. A webcast of the conference call can be accessed at http://investors.10xgenomics.com. The webcast will be archived and available for replay at least 45 days after the event.

About 10x Genomics

10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated research solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn, X, Facebook, Bluesky or YouTube.

Forward Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.'s partnerships, plans, positioning, product launches, organization, goals, opportunities, potential, specifications, costs, enthusiasm, trends and adoption of 10x Genomics, Inc.'s products and services, expected performance advantages and benefits of using 10x Genomics, Inc.'s products and services and 10x Genomics, Inc.'s financial performance and results of operations, including expectations regarding revenue and guidance as well as government policy and academic and government research funding. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2024, filed on February 13, 2025, and the company's quarterly reports on Form 10-Q for the quarter ended March 31, 2025, filed on May 9, 2025, and for the quarter ended June 30, 2025, to be filed with the Securities and Exchange Commission (SEC), and elsewhere in the documents 10x Genomics, Inc. files with the SEC from time to time.

Disclosure Information

10x Genomics uses filings with the Securities and Exchange Commission, its website (https://www.10xgenomics.com/), press releases, public conference calls, public webcasts and its social media accounts as means of disclosing material non-public information and for complying with its disclosure obligations under Regulation FD.

Contacts
Investors: investors@10xgenomics.com
Media: media@10xgenomics.com

   

10x Genomics, Inc.

Condensed Consolidated Statements of Operations

(Unaudited)

(In thousands, except share and per share data)



Three Months Ended
June 30,


Six Months Ended
June 30,


2025


2024


2025


2024

Products and services revenue (1)

$         145,157


$         152,990


$         282,980


$         293,995

License and royalty revenue (1)

27,751


114


44,811


115

Revenue

172,908


153,104


327,791


294,110

Cost of products and services revenue (2)

47,824


48,884


97,262


96,976

Gross profit

125,084


104,220


230,529


197,134

Operating expenses:








Research and development (2)

61,224


62,918


125,469


131,556

Selling, general and administrative (2)

74,434


83,039


164,162


168,813

Gain on settlement

(40,700)



(49,900)


Total operating expenses

94,958


145,957


239,731


300,369

Income (loss) from operations

30,126


(41,737)


(9,202)


(103,235)

Other income (expense):








Interest income

4,271


4,715


7,957


9,451

Interest expense

(3)


(1)


(3)


(2)

Other income (expense), net

2,603


(56)


4,739


(1,096)

Total other income

6,871


4,658


12,693


8,353

Income (loss) before provision for income taxes

36,997


(37,079)


3,491


(94,882)

Provision for income taxes

2,459


818


3,311


2,964

Net income (loss)

$            34,538


$          (37,897)


$                 180


$          (97,846)









Net income (loss) per share, basic

$                0.28


$              (0.32)


$                   —


$              (0.82)

Net income (loss) per share, diluted

$                0.28


$              (0.32)


$                   —


$              (0.82)

Weighted-average shares used to compute net income
(loss) per share, basic

123,755,409


120,066,972


123,183,924


119,461,485

Weighted-average shares used to compute net income
(loss) per share, diluted

124,509,720


120,066,972


124,258,150


119,461,485


(1)     The following table represents revenue by source for the periods indicated (in thousands). Spatial products includes the Company's Visium and Xenium products:

 


Three Months Ended
June 30,


Six Months Ended
June 30,


2025


2024


2025


2024

Instruments








Chromium

$              5,727


$              8,792


$           11,640


$            16,642

Spatial

$              8,770


15,060


$           17,672


32,663

Total instruments revenue

14,497


23,852


29,312


49,305

Consumables








Chromium

85,788


94,108


169,897


178,035

Spatial

36,397


29,254


67,644


55,662

Total consumables revenue

122,185


123,362


237,541


233,697

Services

8,475


5,776


16,127


10,993

Products and services revenue

145,157


152,990


$         282,980


$          293,995

License and royalty revenue

27,751


114


$           44,811


$                 115

Total revenue

$         172,908


$         153,104


$         327,791


$          294,110

 

The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):

 


Three Months Ended
June 30,


Six Months Ended
June 30,


2025


2024


2025


2024

Americas








United States*

$         103,491


$           89,672


$         190,309


$         165,309

Americas (excluding United States)

2,667


3,419


$              6,419


7,412

Total Americas

106,158


93,091


196,728


172,721

Europe, Middle East and Africa

34,734


37,362


66,629


72,083

Asia-Pacific








China

23,170


13,738


40,053


27,662

Asia-Pacific (excluding China)

8,846


8,913


24,381


21,644

Total Asia-Pacific

32,016


22,651


64,434


49,306

Total revenue

$         172,908


$         153,104


$         327,791


$         294,110


* Includes license and royalty revenue.


(2)     Includes stock-based compensation expense as follows:

 


Three Months Ended
June 30,


Six Months Ended
June 30,

(in thousands)

2025


2024


2025


2024

Cost of revenue

$              1,989


$              2,247


$              4,470


$              4,280

Research and development

12,613


17,862


26,719


34,750

Selling, general and administrative

12,643


18,383


27,132


35,591

Total stock-based compensation expense

$            27,245


$            38,492


$            58,321


$            74,621

 

10x Genomics, Inc.

Condensed Consolidated Balance Sheets

(Unaudited)

(In thousands)



June 30,
2025


December 31,
2024

Assets




Current assets:




Cash and cash equivalents

$         397,712


$         344,067

Marketable securities

49,549


49,335

Accounts receivable, net

49,977


87,862

Other receivables

69,090


606

Inventory

68,968


83,107

Prepaid expenses and other current assets

20,365


19,410

Total current assets

655,661


584,387

Property and equipment, net

239,710


252,648

Operating lease right-of-use assets

62,700


57,290

Goodwill

4,511


4,511

Intangible assets, net

14,714


15,671

Other noncurrent assets

2,674


4,129

Total assets

$         979,970


$         918,636

Liabilities and stockholders' equity




Current liabilities:




Accounts payable

$           15,938


$           12,909

Accrued compensation and related benefits

26,102


33,615

Accrued expenses and other current liabilities

39,063


41,165

Deferred revenue

21,449


20,658

Operating lease liabilities

9,669


9,286

Total current liabilities

112,221


117,633

Operating lease liabilities, noncurrent

77,075


73,327

Deferred revenue, noncurrent

11,270


12,513

Other noncurrent liabilities

6,125


5,029

Total liabilities

206,691


208,502

Commitments and contingencies




Stockholders' equity:




Preferred stock


Common stock

2


2

Additional paid-in capital

2,239,924


2,177,672

Accumulated deficit

(1,466,867)


(1,467,047)

Accumulated other comprehensive income (loss)

220


(493)

Total stockholders' equity

773,279


710,134

Total liabilities and stockholders' equity

$         979,970


$         918,636

 

 

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SOURCE 10x Genomics, Inc.

FAQ

What was 10x Genomics (TXG) revenue in Q2 2025?

10x Genomics reported total revenue of $172.9 million, with $145.6 million excluding a $27.3 million patent litigation settlement.

How much did 10x Genomics pay for Scale Biosciences acquisition?

10x Genomics agreed to acquire Scale Biosciences for $30 million in upfront cash and stock, plus additional contingent milestone-based payments.

What is 10x Genomics' Q3 2025 revenue guidance?

10x Genomics expects Q3 2025 revenue between $140-144 million, accounting for $4 million in accelerated Chinese purchases.

How much cash does 10x Genomics have as of Q2 2025?

10x Genomics reported $447.3 million in cash, cash equivalents, and marketable securities, an increase of $20 million from the previous quarter.

What was 10x Genomics' profit/loss in Q2 2025?

10x Genomics reported a net income of $34.5 million, compared to a net loss of $37.9 million in the same period last year.

How did 10x Genomics' gross margin change in Q2 2025?

Gross margin improved to 72% from 68% year-over-year, though excluding license and royalty revenue, it was 67%.
10X Genomics, Inc.

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