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Xilio Therapeutics Announces Closing of $50.0 Million Public Offering

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Xilio Therapeutics (XLO) has completed a public offering raising initial gross proceeds of $50.0 million through pre-funded warrants and common stock warrants. The offering was co-led by Coastlands Capital and Frazier Life Sciences, with participation from Gilead Sciences, Logos Capital, Samsara BioCapital, and other investors. The company issued 66,676,000 pre-funded warrants with accompanying Series A, B, and C warrants. If all Series B and C warrants are exercised at $0.75 per share, Xilio could receive up to an additional $100 million by end of 2026, potentially reaching total gross proceeds of $150 million. The company can cancel warrants proportionally to non-dilutive capital received. Proceeds will support product candidate development and general corporate purposes.
Xilio Therapeutics (XLO) ha completato un'offerta pubblica raccogliendo un ricavato lordo iniziale di 50,0 milioni di dollari tramite warrant prefinanziati e warrant su azioni ordinarie. L'offerta è stata co-guidata da Coastlands Capital e Frazier Life Sciences, con la partecipazione di Gilead Sciences, Logos Capital, Samsara BioCapital e altri investitori. La società ha emesso 66.676.000 warrant prefinanziati accompagnati da warrant delle Serie A, B e C. Se tutti i warrant delle Serie B e C verranno esercitati a 0,75 dollari per azione, Xilio potrebbe ricevere fino a ulteriori 100 milioni di dollari entro la fine del 2026, raggiungendo potenzialmente un ricavato lordo totale di 150 milioni di dollari. L'azienda può cancellare i warrant in modo proporzionale al capitale non diluitivo ricevuto. I proventi sosterranno lo sviluppo dei candidati al prodotto e le finalità aziendali generali.
Xilio Therapeutics (XLO) ha completado una oferta pública recaudando ingresos brutos iniciales de 50,0 millones de dólares a través de warrants prefinanciados y warrants sobre acciones ordinarias. La oferta fue co-liderada por Coastlands Capital y Frazier Life Sciences, con la participación de Gilead Sciences, Logos Capital, Samsara BioCapital y otros inversores. La compañía emitió 66.676.000 warrants prefinanciados acompañados de warrants de las Series A, B y C. Si se ejercen todos los warrants de las Series B y C a 0,75 dólares por acción, Xilio podría recibir hasta 100 millones de dólares adicionales para finales de 2026, alcanzando potencialmente ingresos brutos totales de 150 millones de dólares. La empresa puede cancelar warrants proporcionalmente al capital no dilutivo recibido. Los ingresos apoyarán el desarrollo de candidatos a productos y los propósitos corporativos generales.
Xilio Therapeutics(XLO)는 선행 자금 조달 워런트 및 보통주 워런트를 통해 초기 총 5,000만 달러의 공모를 완료했습니다. 이번 공모는 Coastlands Capital과 Frazier Life Sciences가 공동 주도했으며 Gilead Sciences, Logos Capital, Samsara BioCapital 및 기타 투자자들이 참여했습니다. 회사는 66,676,000개의 선행 자금 조달 워런트와 함께 시리즈 A, B, C 워런트를 발행했습니다. 모든 시리즈 B 및 C 워런트를 주당 0.75달러에 행사할 경우, Xilio는 2026년 말까지 최대 추가 1억 달러를 확보할 수 있어 총 공모 금액이 1억 5천만 달러에 이를 수 있습니다. 회사는 비희석성 자본 확보에 따라 비례적으로 워런트를 취소할 수 있습니다. 조달 자금은 제품 후보 개발 및 일반 기업 목적에 사용될 예정입니다.
Xilio Therapeutics (XLO) a réalisé une offre publique ayant généré un produit brut initial de 50,0 millions de dollars grâce à des bons de souscription préfinancés et des bons de souscription d’actions ordinaires. L’offre a été co-dirigée par Coastlands Capital et Frazier Life Sciences, avec la participation de Gilead Sciences, Logos Capital, Samsara BioCapital et d’autres investisseurs. La société a émis 66 676 000 bons de souscription préfinancés accompagnés de bons des séries A, B et C. Si tous les bons des séries B et C sont exercés au prix de 0,75 $ par action, Xilio pourrait recevoir jusqu’à 100 millions de dollars supplémentaires d’ici fin 2026, atteignant potentiellement un produit brut total de 150 millions de dollars. La société peut annuler les bons proportionnellement au capital non dilutif reçu. Les fonds serviront à soutenir le développement des candidats produits et les besoins généraux de l’entreprise.
Xilio Therapeutics (XLO) hat eine öffentliche Kapitalerhöhung abgeschlossen und dabei anfängliche Bruttoerlöse von 50,0 Millionen US-Dollar durch vorfinanzierte Warrants und Stammaktien-Warrants erzielt. Das Angebot wurde gemeinsam von Coastlands Capital und Frazier Life Sciences geleitet, mit Beteiligung von Gilead Sciences, Logos Capital, Samsara BioCapital und weiteren Investoren. Das Unternehmen hat 66.676.000 vorfinanzierte Warrants zusammen mit den Serien A, B und C Warrants ausgegeben. Wenn alle Serie B- und C-Warrants zum Ausübungspreis von 0,75 US-Dollar pro Aktie eingelöst werden, könnte Xilio bis Ende 2026 zusätzliche 100 Millionen US-Dollar erhalten und damit potenziell Gesamterlöse von 150 Millionen US-Dollar erzielen. Das Unternehmen kann Warrants anteilig im Verhältnis zum erhaltenen nicht verwässernden Kapital stornieren. Die Erlöse dienen der Unterstützung der Entwicklung von Produktkandidaten und allgemeinen Unternehmenszwecken.
Positive
  • Potential to raise up to $150 million in total gross proceeds through warrant exercises
  • Strong investor participation including strategic investor Gilead Sciences
  • Flexibility to cancel warrants proportionate to non-dilutive capital received
  • Immediate access to $50 million in initial gross proceeds
Negative
  • Significant potential dilution from 66.7 million pre-funded warrants and accompanying warrants
  • Additional funding dependent on warrant exercises at $0.75 per share
  • Complex warrant structure may create market uncertainty

Insights

Xilio secures $50M upfront funding with potential for $100M more, significantly extending cash runway for its immuno-oncology pipeline.

Xilio Therapeutics has successfully closed a $50 million public offering co-led by new investors Coastlands Capital and Frazier Life Sciences, with participation from Gilead Sciences and other investors. This complex financing structure includes an innovative mechanism to potentially secure up to $150 million in total gross proceeds through warrant exercises by the end of 2026.

The financing consists of pre-funded warrants to purchase 66,676,000 shares combined with three series of warrants (A, B, and C). The Series B warrants could bring an additional $50 million if exercised between November-December 2025, while Series C warrants could add another $50 million if exercised in the second half of 2026.

What makes this deal particularly noteworthy is the unique non-dilutive capital clause that allows Xilio to cancel outstanding warrants proportionate to any non-dilutive funding it secures. For every dollar of non-dilutive capital (such as partnership revenues or grants), Xilio can cancel 1.33 warrants without compensating warrant holders, effectively reducing future dilution.

The participation of Gilead Sciences is strategically significant, as large pharma investment often signals validation of a biotech's technology platform. For a clinical-stage company developing tumor-activated immuno-oncology therapies, this capital infusion provides crucial runway to advance its pipeline.

This financing structure balances immediate capital needs while creating potential for additional funding tied to future milestones, which aligns investor interests with company progress. The $50 million immediate proceeds will support Xilio's product development and general corporate expenses while maintaining flexibility for future capital optimization.

Total gross proceeds of up to $150.0 million before the end of 2026 if all Series B warrants and Series C warrants are exercised for cash

Xilio may elect to cancel unexercised Series B or Series C warrants proportionately to the amount of non-dilutive capital received, under certain circumstances

Financing co-led by new investors Coastlands Capital and Frazier Life Sciences and included participation from Gilead Sciences, Inc., Logos Capital, Samsara BioCapital and other new and existing investors

WALTHAM, Mass., June 05, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced the closing of its previously announced underwritten public offering of pre-funded warrants and accompanying common stock warrants for initial gross proceeds of approximately $50.0 million before deducting underwriting discounts and commissions and offering expenses. In addition, if all of the Series B warrants and Series C warrants are exercised in cash at their exercise price of $0.75 per warrant, Xilio would receive up to $100.0 million of additional gross proceeds by the second half of 2026, for total gross proceeds of up to $150.0 million before deducting underwriting discounts and commissions and offering expenses. The financing was co-led by new investors Coastlands Capital and Frazier Life Sciences and included participation from Gilead Sciences, Inc., Logos Capital, Samsara BioCapital and other new and existing institutional investors.

Overview of Pre-Funded Warrants and Common Stock Warrants

In connection with the offering, Xilio issued pre-funded warrants to purchase 66,676,000 shares of common stock (the “pre-funded warrants”), accompanied by Series A warrants to purchase 66,676,000 shares of common stock (or, in certain circumstances, pre-funded warrants) (the “Series A warrants”), Series B warrants to purchase 66,676,000 shares of common stock (or, in certain circumstances, pre-funded warrants) (the “Series B warrants”) and Series C warrants to purchase 66,676,000 shares of common stock (or, in certain circumstances, pre-funded warrants) (the “Series C warrants”). The combined public offering price of one pre-funded warrant, one Series A warrant, one Series B warrant and one Series C warrant, which were sold together but are immediately separable, is $0.7499, which is equal to the combined offering price of the pre-funded warrants, Series A warrants, Series B warrants and Series C warrants, less the $0.0001 per share exercise price of the pre-funded warrants. The offering closed on June 5, 2025, and all of the warrants were sold by Xilio.

The pre-funded warrants and Series A warrants may be exercised for cash or on a net exercise or “cashless” basis, and the Series B warrants and Series C warrants may be exercised for cash or on a net exercise or “cashless” basis provided there is no effective registration statement or prospectus available which covers the Series B warrants and Series C warrants and shares of common stock issuable upon exercise of the Series B warrants and Series C warrants.

The Series B warrants are exercisable at an exercise price of $0.75 per share of common stock between November 1, 2025 and December 2, 2025, subject to the terms of the warrant. If all of the Series B warrants are exercised for cash at their exercise price, Xilio would receive up to $50.0 million in additional gross proceeds before the end of 2025. The Series C warrants are exercisable at an exercise price of $0.75 per share of common stock between June 1, 2026 and December 2, 2026, subject to the terms of the warrant. If all of the Series C warrants are exercised for cash at their exercise price, Xilio would receive up to $50.0 million in additional gross proceeds before the end of 2026. In addition, for each dollar of non-dilutive capital received by Xilio prior to the exercise or expiration of the Series B and Series C warrants, Xilio may elect to cancel a number of warrant shares equal to $1.00 divided by the $0.75 warrant exercise price (or one and one-third warrants) without any compensation paid by Xilio to the warrant holders. For example, if Xilio received $30.0 million in non-dilutive capital, it could elect to cancel 40.0 million of warrant shares.

Xilio intends to use the net proceeds received from the offering to advance the development of its product candidates and for working capital requirements and other general corporate purposes.

Leerink Partners acted as the sole bookrunner for the offering.

A shelf registration statement on Form S-3 (File No. 333-285703), as amended, relating to the securities to be offered in the public offering was initially filed with the Securities and Exchange Commission (the “SEC”) on March 11, 2025, and declared effective on May 8, 2025. The offering was made only by means of a prospectus supplement and accompanying prospectus that form a part of the registration statement. A final prospectus supplement relating to the offering has been filed with the SEC and may be obtained for free by visiting the SEC’s website at www.sec.gov. Copies of the preliminary prospectus supplement and final prospectus supplement relating to the offering may also be obtained by contacting Leerink Partners LLC, Syndicate Department, 53 State Street, 40th Floor, Boston, MA 02109, or by telephone at (800) 808-7525 ext. 6105, or by email at syndicate@leerink.com.

This press release shall not constitute an offer to sell, or a solicitation of an offer to buy these securities, nor shall there be any sale of, these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Xilio Therapeutics

Xilio Therapeutics is a clinical-stage biotechnology company discovering and developing tumor-activated, or masked, immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. The company is leveraging its proprietary platform to advance a pipeline of novel, tumor-activated I-O molecules that are designed to optimize the therapeutic index by localizing anti-tumor activity within the tumor microenvironment.

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, statements regarding the use of proceeds of the offering. The words “aim,” “may,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “seek,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management’s current expectations and beliefs and are subject to a number of important risks, uncertainties and other factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release. These and other risks and uncertainties are described in greater detail in the sections entitled “Risk Factor Summary” and “Risk Factors” in Xilio’s filings with the SEC, including Xilio’s most recent Quarterly Report on Form 10-Q and any other filings that Xilio has made or may make with the SEC in the future. Any forward-looking statements contained in this press release represent Xilio’s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date. Except as required by law, Xilio explicitly disclaims any obligation to update any forward-looking statements.

Investor and Media Contact 

Scott Young
Vice President, Investor Relations and Corporate Communications
investors@xiliotx.com 


FAQ

How much did Xilio Therapeutics (XLO) raise in its June 2025 public offering?

Xilio raised initial gross proceeds of $50.0 million, with potential for additional $100 million if all Series B and C warrants are exercised, totaling up to $150 million.

What is the exercise price for XLO's Series B and C warrants?

Both Series B and Series C warrants have an exercise price of $0.75 per share of common stock.

Who were the lead investors in Xilio's 2025 public offering?

The offering was co-led by new investors Coastlands Capital and Frazier Life Sciences, with participation from Gilead Sciences, Logos Capital, and Samsara BioCapital.

When can XLO's Series B and C warrants be exercised?

Series B warrants are exercisable between November 1-December 2, 2025, and Series C warrants between June 1-December 2, 2026.

How will Xilio use the proceeds from the offering?

Xilio intends to use the net proceeds to advance the development of its product candidates and for working capital and general corporate purposes.
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