XOMA Royalty Reports Second Quarter and Year to Date 2025 Financial Results and Highlights Recent Business Achievements
Rhea-AI Summary
XOMA Royalty (NASDAQ:XOMA) reported Q2 2025 financial results and significant business developments. The company received $29.6 million in royalties and milestones in H1 2025, including $11.7 million in Q2. Notable achievements include the acquisition of multiple companies (Turnstone Biologics, LAVA Therapeutics, and HilleVax) and the $20 million purchase of mezagitamab royalty rights from BioInvent.
Q2 2025 financial highlights include net income of $9.2 million and total income/revenue of $13.1 million. The company ended Q2 with $78.5 million in cash and cash equivalents. Several pipeline advancements were reported, including Rezolute's completion of Phase 3 enrollment for ersodetug and EMA's acceptance of Day One's tovorafenib MAA.
[ "Received $29.6 million in royalties and milestones in H1 2025", "Net income of $9.2 million in Q2 2025, up from $7.4 million in Q2 2024", "Strategic acquisitions of Turnstone Biologics, LAVA Therapeutics, and HilleVax expanding portfolio", "Strong cash position of $78.5 million as of June 30, 2025", "Multiple pipeline advancements including regulatory milestones and Phase 3 trial progress", "Decreased G&A expenses to $7.8 million in Q2 2025 from $11.0 million in Q2 2024" ]Positive
- None.
Negative
- Cash and cash equivalents decreased from $106.4 million in December 2024 to $78.5 million in June 2025
- Significant capital deployment for acquisitions may impact short-term liquidity
News Market Reaction
On the day this news was published, XOMA gained 8.54%, reflecting a notable positive market reaction. Argus tracked a peak move of +10.3% during that session. Argus tracked a trough of -10.0% from its starting point during tracking. Our momentum scanner triggered 8 alerts that day, indicating moderate trading interest and price volatility. This price movement added approximately $31M to the company's valuation, bringing the market cap to $396M at that time. Trading volume was elevated at 2.5x the daily average, suggesting notable buying interest.
Data tracked by StockTitan Argus on the day of publication.
Business development: Purchased mezagitamab royalty and milestone rights held by BioInvent International and will secure royalty economic interests in two early-stage partnered assets through XOMA Royalty’s recently announced acquisition of LAVA Therapeutics.
Company acquisitions: Announced XOMA Royalty’s acquisitions of Turnstone Biologics, LAVA Therapeutics, and HilleVax; acted as structuring agent and provided financing for XenoTherapeutics’ acquisition of ESSA Pharma; completed the sale of Kinnate pipeline assets and distributed upfront proceeds to Kinnate contingent value right (CVR) holders.
Key Pipeline advancements: Rezolute completed enrollment in Phase 3 sunRIZE study of ersodetug in patients with congenital hyperinsulinism; the Marketing Authorization Application (MAA) for Day One Biopharmaceuticals and Ipsen’s tovorafenib was accepted for review by the European Marketing Authority (EMA), resulting in a
Cash receipts: In the first half of 2025, XOMA Royalty received
EMERYVILLE, Calif., Aug. 13, 2025 (GLOBE NEWSWIRE) -- XOMA Royalty Corporation (NASDAQ: XOMA), the biotech royalty aggregator, reported its 2025 second quarter and year to date financial results and highlighted recent actions that have the potential to deliver shareholder value.
“We continue to add to our diversified portfolio of both early- and late-stage assets through disciplined capital deployment and creative financial structures,” stated Owen Hughes, Chief Executive Officer of XOMA Royalty. “Recently approved drugs are addressing key unmet patient needs, which is driving increased royalty receipts, and we await data from several key Phase 3 assets over the coming quarters.”
Royalty and Milestone Acquisitions
| Company | Asset and Transaction Detail |
| BioInvent | XOMA Royalty deployed |
| LAVA Therapeutics | XOMA Royalty will secure an economic interest in two partnered assets through the Company’s recently announced acquisition of LAVA. The partnered assets are PF-08046052, which is being developed by Pfizer, and JNJ-89853413, which is being developed by Johnson & Johnson. |
Company Acquisitions
| Company | Transaction Details |
| Turnstone Biologics | XOMA Royalty and Turnstone Biologics entered into a definitive merger agreement, whereby XOMA Royalty will acquire Turnstone for |
| HilleVax | XOMA Royalty and HilleVax have entered into a definitive merger agreement, whereby XOMA Royalty will acquire HilleVax for |
| LAVA Therapeutics | XOMA Royalty and LAVA Therapeutics have entered into a definitive merger agreement, whereby XOMA Royalty will acquire LAVA for between |
| XenoTherapeutics Acquisition of ESSA Pharma | XOMA Royalty acted as structuring agent and is providing short-term financing for XenoTherapeutics’ acquisition of ESSA Pharma. |
| Kinnate | XOMA Royalty sold the remaining Kinnate pipeline assets for a total of up to |
Pipeline Partner Updates through August 8, 2025
| Partner | Event |
| Rezolute | In May, the company announced the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation (BTD) to its investigational therapy, ersodetug, for the treatment of hypoglycemia caused by tumor HI.1 |
| In May, Rezolute announced the completion of enrollment in the Phase 3 sunRIZE study. Topline data are anticipated in December of 2025.2As a result of Rezolute completing enrollment in the study, XOMA Royalty received a | |
| Takeda | The first patient was dosed in Takeda’s Phase 3 clinical trial investigating mezagitamab as a treatment for adults with chronic primary immune thrombocytopenia (ITP). This achievement resulted in XOMA Royalty receiving a |
| Day One Biopharmaceuticals | Ipsen, Day One’s partner outside of the U.S., announced its Marketing Authorization Application (MAA) for tovorafenib as a treatment for pediatric low-grade glioma (pLGG) had been accepted for review by the European Medicines Agency (EMA)3. |
| Zevra Therapeutics | On July 28, Zevra announced it had submitted an MAA to EMA for the evaluation of arimoclomol for the treatment of Niemann-Pick Disease Type C (NPC)4. |
| Gossamer Bio | On June 16, Gossamer announced it had completed enrollment in the ongoing Phase 3 PROSERA Study that is evaluating seralutinib in Functional Class II and III pulmonary atrial hypertension (PAH) patients5. Topline results continue to be anticipated in February 20266. |
| Daré Biosciences | Announced positive interim safety and efficacy results from its ongoing Phase 3 clinical trial evaluating the contraceptive effectiveness, safety, and acceptability of Ovaprene®, an investigational monthly, hormone-free intravaginal contraceptive.7 |
Anticipated 2025 Partner Events of Note
| Partner | Event |
| Rezolute | Topline data from sunRIZE Phase 3 clinical trial, which is investigating ersodetug in infants and children with congenital hyperinsulinism (cHI). Topline data are expected in December 20252. |
| First patient dosed in the Phase 3 registrational study for ersodetug for the treatment of hypoglycemia due to tumor hyperinsulinism8. | |
| Takeda | First patient dosed in Takeda’s Phase 3 clinical trial investigating mezagitamab as a treatment for adults with IgA Nephropathy. |
| Gossamer Bio | Activates first clinical sites for the global, registrational Phase 3 SERANATA Study examining seralutinib in patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD) in the fourth quarter5. |
| Daré Bioscience | Makes Sildenafil Cream, |
| Commencement of one of two registrational Phase 3 clinical trials investigating Sildenafil Cream, |
Second Quarter and Year to Date 2025 Financial Results
Tom Burns, Chief Financial Officer of XOMA Royalty, commented, “In the first six months of 2025, we have received
Income and Revenue: Income and revenue for the three and six months ended June 30, 2025, were
Research and Development (R&D) Expenses: R&D expenses for the three and six months ended June 30, 2025, were
General and Administrative (G&A) Expenses: G&A expenses for the three and six months ended June 30, 2025, were
In 2025, XOMA Royalty’s G&A expenses included non-cash stock-based compensation expenses during the three and six months ended June 30, 2025, of
Credit Losses on Purchased Receivables: In the second quarter of 2024, XOMA Royalty recorded a one-time, non-cash credit loss on purchased receivables of
Amortization of Intangible Assets: Amortization of intangible assets relates to the IP acquired in the Company’s acquisitions of Pulmokine in November 2024 and the mezagitamab economics from the BioInvent transaction in May 2025. Amortization of non-cash intangible assets were
Gain on Acquisition of Kinnate: In the second quarter of 2024, XOMA Royalty recorded a
Interest Expense: For the three and six months ended June 30, 2025, interest expense was
Other Income, net: For the three and six months ended June 30, 2025, other income, net was
Net Income: XOMA Royalty reported net income of
Cash Position: On June 30, 2025, XOMA Royalty had cash and cash equivalents of
In the second quarter of 2025, XOMA Royalty received
About XOMA Royalty Corporation
XOMA Royalty is a biotechnology royalty aggregator playing a distinctive role in helping biotech companies achieve their goal of improving human health. XOMA Royalty acquires the potential future economics associated with pre-commercial and commercial therapeutic candidates that have been licensed to pharmaceutical or biotechnology companies. When XOMA Royalty acquires the future economics, the seller receives non-dilutive, non-recourse funding they can use to advance their internal drug candidate(s) or for general corporate purposes. The Company has an extensive and growing portfolio of assets (asset defined as the right to receive potential future economics associated with the advancement of an underlying therapeutic candidate). For more information about the Company and its portfolio, please visit www.xoma.com or follow XOMA Royalty Corporation on LinkedIn.
Forward-Looking Statements/Explanatory Notes
Certain statements contained in this press release are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, including statements regarding the timing and amount of potential commercial payments to XOMA Royalty and other developments related to VABYSMO® (faricimab-svoa), OJEMDA™ (tovorafenib), MIPLYFFA™ (arimoclomol), XACIATO™ (clindamycin phosphate) vaginal gel
EXPLANATORY NOTE: Any references to “portfolio” in this press release refer strictly to milestone and/or royalty rights associated with a basket of drug products in development. Any references to “assets” in this press release refer strictly to milestone and/or royalty rights associated with individual drug products in development.
As of the date of this press release, the commercial assets in XOMA Royalty’s milestone and royalty portfolio are VABYSMO® (faricimab-svoa), OJEMDA™ (tovorafenib), MIPLYFFA™ (arimoclomol), XACIATO™ (clindamycin phosphate) vaginal gel
1 https://ir.rezolutebio.com/news/detail/354/rezolute-receives-breakthrough-therapy-designation-from-fda-for-ersodetug-in-the-treatment-of-hypoglycemia-due-to-tumor-hyperinsulinism
2 https://ir.rezolutebio.com/news/detail/356/rezolute-announces-completion-of-enrollment-in-the-phase-3-sunrize-study-of-ersodetug-in-patients-with-congenital-hyperinsulinism
3 https://www.ipsen.com/press-releases/ipsen-delivers-strong-sales-in-the-first-quarter-2025-and-confirms-its-full-year-guidance-3062256/
4 https://investors.zevra.com/news-releases/news-release-details/zevra-therapeutics-submits-marketing-authorization-application
5 https://ir.gossamerbio.com/news-releases/news-release-details/gossamer-bio-announces-completion-enrollment-registrational
6 https://ir.gossamerbio.com/news-releases/news-release-details/gossamer-bio-announces-second-quarter-2025-financial-results-and
7 https://ir.darebioscience.com/news-releases/news-release-details/positive-interim-phase-3-results-highlight-potential-ovaprener
8 https://ir.rezolutebio.com/news/detail/337/rezolute-announces-fda-clearance-of-ind-application-for-phase-3-registrational-study-of-rz358-for-treatment-of-hypoglycemia-due-to-tumor-hyperinsulinism
9 https://ir.darebioscience.com/news-releases/news-release-details/dare-bioscience-and-rosy-wellness-announce-strategic
10 https://ir.darebioscience.com/news-releases/news-release-details/dare-bioscience-announces-phase-3-plans-sildenafil-cream-36
| XOMA CORPORATION | |||||||||||||||
| CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS | |||||||||||||||
| (unaudited) | |||||||||||||||
| (in thousands, except share and per share amounts) | |||||||||||||||
| Three Months Ended June, | Six Month Ended June 30, | ||||||||||||||
| 2025 | 2024 | 2025 | 2024 | ||||||||||||
| Income and Revenues: | |||||||||||||||
| Income from purchased receivables under the EIR method | $ | 6,007 | $ | 4,562 | $ | 12,077 | $ | 4,562 | |||||||
| Income from purchased receivables under the cost recovery method | 1,743 | 870 | 7,268 | 870 | |||||||||||
| Revenue from contracts with customers | 5,025 | 5,025 | 9,025 | 6,025 | |||||||||||
| Revenue recognized under units-of-revenue method | 354 | 629 | 671 | 1,119 | |||||||||||
| Total income and revenues | 13,129 | 11,086 | 29,041 | 12,576 | |||||||||||
| Operating expenses: | |||||||||||||||
| Research and development | 69 | 1,161 | 1,362 | 1,194 | |||||||||||
| General and administrative | 7,802 | 11,004 | 15,948 | 19,465 | |||||||||||
| Credit losses on purchased receivables | - | 9,000 | - | 9,000 | |||||||||||
| Amortization of intangible assets | 655 | - | 1,199 | - | |||||||||||
| Total operating expenses | 8,526 | 21,165 | 18,509 | 29,659 | |||||||||||
| Income (Loss) from operations | 4,603 | (10,079 | ) | 10,532 | (17,083 | ) | |||||||||
| Other income (expense) | |||||||||||||||
| Gain on the acquisition of Kinnate | - | 19,316 | - | 19,316 | |||||||||||
| Change in fair value of embedded derivative related to RPA | - | 8,100 | - | 8,100 | |||||||||||
| Interest expense | (3,236 | ) | (3,402 | ) | (6,703 | ) | (6,953 | ) | |||||||
| Other income, net | 7,824 | 2,050 | 7,729 | 4,010 | |||||||||||
| Net income | $ | 9,191 | $ | 15,985 | $ | 11,558 | $ | 7,390 | |||||||
| Net income available to common stockholders, basic | $ | 5,522 | $ | 10,224 | $ | 6,225 | $ | 3,253 | |||||||
| Basic net income per share available to common stockholders | $ | 0.46 | $ | 0.88 | $ | 0.52 | $ | 0.28 | |||||||
| Weighted average shares used in computing basic net income per share available to common stockholders | 12,007 | 11,643 | 11,988 | 11,611 | |||||||||||
| Net income available to common stockholders, diluted | $ | 7,823 | $ | 14,617 | $ | 8,822 | $ | 4,654 | |||||||
| Diluted net income per share available to common stockholders | $ | 0.44 | $ | 0.84 | $ | 0.50 | $ | 0.27 | |||||||
| Weighted average shares used in computing diluted net income per share available to common stockholders | 17,761 | 17,321 | 17,777 | 17,263 | |||||||||||
| XOMA CORPORATION | |||||||
| CONDENSED CONSOLIDATED BALANCE SHEETS | |||||||
| (unaudited) | |||||||
| (in thousands, except share and per share amounts) | |||||||
| June 30, | December 31, | ||||||
| 2025 | 2024 | ||||||
| ASSETS | |||||||
| Current assets: | |||||||
| Cash and cash equivalents | $ | 75,060 | $ | 101,654 | |||
| Short-term restricted cash | 80 | 1,330 | |||||
| Investment in equity securities | 8,801 | 3,529 | |||||
| Trade and other receivables, net | 1,817 | 1,839 | |||||
| Short-term royalty and commercial payment receivables under the EIR method | 17,960 | 14,763 | |||||
| Short-term royalty and commercial payment receivables under the cost recovery method | 700 | 413 | |||||
| Prepaid expenses and other current assets | 507 | 2,076 | |||||
| Total current assets | 104,925 | 125,604 | |||||
| Long-term restricted cash | 3,345 | 3,432 | |||||
| Property and equipment, net | 26 | 32 | |||||
| Operating lease right-of-use assets | 288 | 319 | |||||
| Long-term royalty and commercial payment receivables under the EIR method | 4,775 | 4,970 | |||||
| Long-term royalty and commercial payment receivables under the cost recovery method | 58,937 | 55,936 | |||||
| Exarafenib milestone asset (Note 4) | 3,402 | 3,214 | |||||
| Investment in warrants | 609 | - | |||||
| Intangible assets, net | 45,434 | 25,909 | |||||
| Other assets - long term | 1,715 | 1,861 | |||||
| Total assets | $ | 223,456 | $ | 221,277 | |||
| LIABILITIES, CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ EQUITY | |||||||
| Current liabilities: | |||||||
| Accounts payable | $ | 1,138 | $ | 1,053 | |||
| Accrued and other liabilities | 5,411 | 5,752 | |||||
| Contingent consideration under RPAs, AAAs, and CPPAs | - | 3,000 | |||||
| Operating lease liabilities | 472 | 446 | |||||
| Unearned revenue recognized under units-of-revenue method | 1,434 | 1,361 | |||||
| Preferred stock dividend accrual | 1,368 | 1,368 | |||||
| Current portion of long-term debt | 11,672 | 11,394 | |||||
| Total current liabilities | 21,495 | 24,374 | |||||
| Unearned revenue recognized under units-of-revenue method – long-term | 3,666 | 4,410 | |||||
| Exarafenib milestone contingent consideration | 3,402 | 3,214 | |||||
| Long-term operating lease liabilities | 238 | 483 | |||||
| Long-term debt | 102,201 | 106,875 | |||||
| Total liabilities | 131,002 | 139,356 | |||||
| Convertible preferred stock, | 20,019 | 20,019 | |||||
| Stockholders’ equity: | |||||||
| 49 | 49 | ||||||
| — | — | ||||||
| Common stock, | 90 | 90 | |||||
| Additional paid-in capital | 1,300,066 | 1,298,747 | |||||
| Accumulated other comprehensive income | 122 | 73 | |||||
| Accumulated deficit | (1,227,892 | ) | (1,237,057 | ) | |||
| Total stockholders’ equity | 72,435 | 61,902 | |||||
| Total liabilities, convertible preferred stock and stockholders’ equity | $ | 223,456 | $ | 221,277 | |||
| XOMA CORPORATION | |||||||
| CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS | |||||||
| (unaudited) | |||||||
| (in thousands) | |||||||
| Six Months Ended June 30, | |||||||
| 2025 | 2024 | ||||||
| Cash flows from operating activities: | |||||||
| Net income | $ | 11,558 | $ | 7,390 | |||
| Adjustments to reconcile net income to net cash provided by (used in) operating activities: | |||||||
| Adjustment for income from EIR method purchased receivables | (3,935 | ) | (4,562 | ) | |||
| Stock-based compensation expense | 3,588 | 5,546 | |||||
| Credit losses on purchased receivables | — | 9,000 | |||||
| Gain on the acquisition of Kinnate | — | (19,316 | ) | ||||
| Common stock contribution to 401(k) | 141 | 118 | |||||
| Amortization of intangible assets | 1,199 | — | |||||
| Depreciation | 6 | 5 | |||||
| Accretion of long-term debt discount and debt issuance costs | 749 | 508 | |||||
| Non-cash lease expense | 31 | 29 | |||||
| Change in fair value of equity securities | (5,173 | ) | (535 | ) | |||
| Change in fair value of available-for-sale debt securities classified as cash equivalents | 49 | — | |||||
| Change in fair value of derivatives | (5 | ) | — | ||||
| Changes in assets and liabilities: | |||||||
| Trade and other receivables, net | 22 | 478 | |||||
| Prepaid expenses and other assets | 1,715 | (603 | ) | ||||
| Accounts payable and accrued liabilities | (387 | ) | 921 | ||||
| Operating lease liabilities | (219 | ) | (82 | ) | |||
| Unearned revenue recognized under units-of-revenue method | (671 | ) | (1,117 | ) | |||
| Net cash provided by (used in) operating activities | 8,668 | (2,220 | ) | ||||
| Cash flows from investing activities: | |||||||
| Net cash acquired in Kinnate acquisition | — | 18,926 | |||||
| Payments of consideration under RPAs, AAAs, and CPPAs | (8,000 | ) | (37,000 | ) | |||
| Receipts under RPAs, AAAs, and CPPAs | 2,039 | 16,741 | |||||
| Payment for BioInvent contract-based intangible asset | (20,614 | ) | — | ||||
| Purchase of property and equipment | — | (17 | ) | ||||
| Purchase of equity securities | (99 | ) | — | ||||
| Net cash used in investing activities | (26,674 | ) | (1,350 | ) | |||
| Cash flows from financing activities: | |||||||
| Principal payments – debt | (5,065 | ) | (3,616 | ) | |||
| Debt issuance costs and loan fees paid in connection with long-term debt | (80 | ) | (661 | ) | |||
| Payment of preferred stock dividends | (2,736 | ) | (2,736 | ) | |||
| Repurchases of common stock | (2,370 | ) | (13 | ) | |||
| Proceeds from exercise of options and other share-based compensation | 896 | 2,353 | |||||
| Taxes paid related to net share settlement of equity awards | (570 | ) | (1,387 | ) | |||
| Net cash used in financing activities | (9,925 | ) | (6,060 | ) | |||
| Net decrease in cash, cash equivalents and restricted cash | (27,931 | ) | (9,630 | ) | |||
| Cash, cash equivalents and restricted cash at the beginning of the period | 106,416 | 159,550 | |||||
| Cash, cash equivalents and restricted cash at the end of the period | $ | 78,485 | $ | 149,920 | |||
| Supplemental Cash Flow Information: | |||||||
| Cash paid for interest | $ | 6,078 | $ | 3,780 | |||
| Cash paid for taxes | $ | 277 | $ | — | |||
| Non-cash investing and financing activities: | |||||||
| Estimated fair value of the Exarafenib milestone asset | $ | — | $ | 2,922 | |||
| Estimated fair value of the Exarafenib milestone contingent consideration | $ | — | $ | 2,922 | |||
| Right-of-use assets obtained in exchange for operating lease liabilities in Kinnate acquisition | $ | — | $ | 824 | |||
| Relative fair value basis reduction of rights-of-use assets in Kinnate acquisition | $ | — | $ | (824 | ) | ||
| Accrual of contingent consideration under the Affitech CPPA | $ | — | $ | 3,000 | |||
| Preferred stock dividend accrual | $ | 1,368 | $ | 1,368 | |||
| Excise tax accrual due to stock repurchases | $ | 24 | $ | — | |||
| Transaction costs in connection with BioInvent IP acquisition included in accounts payable | $ | 111 | $ | — | |||
| Investor contact: | Media contact: |
| Juliane Snowden | Kathy Vincent |
| XOMA Royalty Corporation | KV Consulting & Management |
| +1-646-438-9754 | kathy@kathyvincent.com |
| juliane.snowden@xoma.com |