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22nd Century Group Reports Fourth Quarter and Full Year 2025 Financial Results

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22nd Century Group (Nasdaq: XXII) reported Q4 2025 net revenues of $3.5M and year 2025 revenues of $17.6M, with continuing operations net loss of $2.8M in Q4 and $13.1M for the year.

The company exited 2025 debt-free with $7.1M cash, recovered a $9.5M insurance settlement, eliminated >$8.0M legacy debt, and expanded VLN® retail/state authorizations across multiple partner brands.

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Positive

  • Exited 2025 debt-free
  • Ended year with $7.1M cash
  • Secured $9.5M insurance settlement
  • Eliminated over $8.0M legacy debt
  • VLN® availability expanded to 48 states for company brand

Negative

  • 2025 revenues declined 27.9% YoY to $17.6M
  • Gross loss increased $0.737M (30.7%) for year
  • Full-year net loss from continuing operations $13.1M
  • Adjusted EBITDA loss of $10.2M for 2025
  • VLN® product net revenues only $0.1M in Q4

News Market Reaction – XXII

-10.64% 1.8x vol
12 alerts
-10.64% News Effect
-29.8% Trough in 31 hr 22 min
-$236K Valuation Impact
$1.99M Market Cap
1.8x Rel. Volume

On the day this news was published, XXII declined 10.64%, reflecting a significant negative market reaction. Argus tracked a trough of -29.8% from its starting point during tracking. Our momentum scanner triggered 12 alerts that day, indicating notable trading interest and price volatility. This price movement removed approximately $236K from the company's valuation, bringing the market cap to $1.99M at that time. Trading volume was above average at 1.8x the daily average, suggesting increased trading activity.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Q4 2025 net revenue: $3.5M Q4 2025 net loss: $2.8M FY 2025 net revenue: $17.6M +5 more
8 metrics
Q4 2025 net revenue $3.5M Quarter ended December 31, 2025; down from $4.0M in Q3 2025
Q4 2025 net loss $2.8M Quarter ended December 31, 2025; improved from $3.8M loss in Q3 2025
FY 2025 net revenue $17.6M Year ended December 31, 2025; down from $24.4M in 2024
FY 2025 net loss $13.1M Year ended December 31, 2025; improved from $15.5M loss in 2024
Year-end cash $7.1M Cash at December 31, 2025
Debt eliminated >$8.0M Legacy debt removed in 2025 via repayment, settlement, exchange
Insurance settlement $9.5M Non-dilutive claim related to 2022 Grass Valley facility fire
VLN® cartons shipped 8,800 cartons New branded VLN® and partner VLN® products in Q4 2025

Market Reality Check

Price: $2.41 Vol: Volume 17,484 vs 20-day a...
low vol
$2.41 Last Close
Volume Volume 17,484 vs 20-day average 32,388, with relative volume at 0.54 ahead of this earnings release. low
Technical Shares traded well below the 200-day MA, at $3.29 versus the 200-day moving average of $34.58, reflecting a weak longer-term trend into earnings.

Peers on Argus

Sector peers showed mixed, mostly negative moves: KAVL -18.26%, GNLN -3.59%, TPB...
1 Down

Sector peers showed mixed, mostly negative moves: KAVL -18.26%, GNLN -3.59%, TPB -0.80%, while UVV was up 0.66%. XXII’s -4.08% move appears more company-specific than part of a broad tobacco rotation.

Previous Earnings Reports

5 past events · Latest: Feb 20 (Negative)
Same Type Pattern 5 events
Date Event Sentiment Move Catalyst
Feb 20 Prelim FY25 results Negative -15.6% Preliminary 2025 results with revenue down and continued net losses.
Aug 14 Q2 2025 earnings Negative -10.1% Q2 2025 revenue decline, net loss and adjusted EBITDA loss despite VLN® expansion.
May 13 Q1 2025 earnings Neutral +7.5% Q1 2025 revenue growth but ongoing gross loss and net loss after restructuring.
Mar 20 FY 2024 results Negative -2.6% Q4 and 2024 results with declining revenues and larger net loss.
Nov 12 Q3 2024 earnings Negative -2.4% Q3 2024 revenue drop and widening operating and net losses.
Pattern Detected

Earnings releases have typically been followed by negative price reactions, with an average move of -4.67%, especially when they highlight revenue declines and ongoing losses.

Recent Company History

Over recent earnings cycles, 22nd Century has reported declining or pressured revenues alongside persistent losses, while gradually improving operating metrics. Q3 and Q4 2024 showed revenue declines and larger losses, followed in Q1 and Q2 2025 by better cost control and volume gains but continued net losses. The preliminary Q4 and full-year 2025 report on Feb 20, 2026 emphasized narrower losses and a cash position of $7.1M. Today’s audited results largely confirm that trajectory of modest financial improvement amid top-line pressure.

Historical Comparison

-4.7% avg move · Earnings headlines over the past five events saw an average move of -4.67%. Today’s -4.08% reaction ...
earnings
-4.7%
Average Historical Move earnings

Earnings headlines over the past five events saw an average move of -4.67%. Today’s -4.08% reaction to audited Q4/FY25 results is broadly in line with that pattern.

Earnings updates have shown a progression from deeper 2024 losses and revenue declines toward 2025 results with narrower operating and net losses, higher carton volumes, and broader VLN® distribution, but without restoring prior revenue levels.

Regulatory & Risk Context

Active S-3 Shelf
Shelf Active
Active S-3 Shelf Registration 2025-06-20

An effective Form S-3 shelf filed on Jun 20, 2025 registers up to 8,588,811 resale shares from prior warrant issuances. These cashless-exercise warrants add no cash but can increase tradable float and dilute EPS and ownership percentages as shares are resold.

Market Pulse Summary

The stock dropped -10.6% in the session following this news. A negative reaction despite elements of...
Analysis

The stock dropped -10.6% in the session following this news. A negative reaction despite elements of balance-sheet improvement fits past earnings patterns, which averaged around -4.67% moves. Revenues fell to $17.6M in 2025 from $24.4M in 2024, and the business still generated a $13.1M net loss. Selling pressure could also reflect concern about overhang from registered preferred stock, warrants, and up to 8.6M resale shares under the existing shelf registration.

Key Terms

adjusted ebitda, non-gaap, modified risk tobacco product (mrtp), fda authorization, +1 more
5 terms
adjusted ebitda financial
"Adjusted EBITDA loss was $2.4 million, compared to a loss of $2.9 million."
Adjusted EBITDA is a way companies measure how much money they make from their core operations, like running a business, by removing certain costs or income that aren’t part of regular business activities. It helps investors see how well a company is doing without distractions from unusual expenses or gains, making it easier to compare companies or track performance over time.
non-gaap financial
"Adjusted EBITDA is a non-GAAP financial measure."
Non-GAAP refers to financial measures that companies use to show their earnings or performance without including certain expenses or income that are often added back to give a different picture. It matters because it can make a company's results look better or more favorable, but it may also hide important costs, so investors need to look at both GAAP (official rules) and non-GAAP numbers to get a full understanding.
modified risk tobacco product (mrtp) regulatory
"evaluated as part of the FDA’s Modified Risk Tobacco Product (MRTP) authorization process"
A modified risk tobacco product (MRTP) is a tobacco or nicotine product that a regulator has reviewed and allowed to be marketed with claims that it reduces harm or exposure compared with conventional tobacco. Think of it like an official safety rating for a product — it changes what can be said in advertising, how it can be labeled, and how consumers perceive it. For investors, MRTP status can alter sales potential, competitive position, regulatory risk, and legal exposure, making it a material factor in valuation and strategy.
fda authorization regulatory
"VLN® low nicotine combustible cigarettes were authorized in December 2021"
FDA authorization is the formal permission from the U.S. Food and Drug Administration that allows a drug, medical device, diagnostic test, or vaccine to be marketed or used for a specific purpose after the agency reviews safety and effectiveness evidence. For investors, it’s a key milestone because it opens a product to sales and reimbursement like a building permit opens construction — it can significantly reduce regulatory risk and unlock revenue potential.
u.s. food and drug administration regulatory
"the only combustible cigarettes authorized by the U.S. Food and Drug Administration"
The U.S. Food and Drug Administration is the federal agency that evaluates and enforces safety, effectiveness and labeling standards for medicines, medical devices, vaccines, food and related products before they reach consumers. For investors it matters because FDA approvals, warnings or recalls determine whether a product can be sold, how quickly it reaches the market and how costly compliance will be—changes that directly affect a company’s revenue, costs and stock value.

AI-generated analysis. Not financial advice.

VLN® Commercial Expansion Drives Continued Shift Toward Higher Margin Proprietary Branded Products

Expanding VLN® Store Counts and State Authorizations Increase Availability of Smoking Harm Reduction Products

MOCKSVILLE, N.C., March 26, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company focused on reducing the harms of smoking through nicotine reduction, today announced results for the fourth quarter and fiscal year-ended December 31, 2025, and provided an update on recent business highlights.

The Company’s proprietary low nicotine technology is designed to serve adult smokers who want to change their smoking habits by significantly reducing nicotine consumption. 22nd Century is focusing on smoker health and wellness by giving smokers an opportunity to control their tobacco consumption.

“During 2025, we executed a strategic pivot toward higher-margin branded products, expanded partnerships with established retail chains, and developed a new tobacco harm reduction category, all of which we continue to build upon in 2026. With multiple VLN® and partner product formats now actively selling in the market, we are especially focused on steadily expanding the number of retail chains and total outlets carrying VLN® products,” said Larry Firestone, CEO of 22nd Century Group.

Firestone continued, “Our strategy and business model now enable tobacco companies of any size to adopt a Partner VLN® or licensing pathway with speed and scalability. For the first time, this creates a viable model for the industry to broaden the reach of VLN® products and meaningfully deliver on its stated commitment to tobacco harm reduction.”

“We also made important progress in 2025 to strengthen our financial position as we shifted our focus from restructuring to growth. We exited the year debt-free, with a more efficient operating structure and sufficient capital to support our near-term growth objectives. During the year, we eliminated over $8.0 million of legacy debt through repayment, settlement, and exchange, improving our balance sheet and reducing our cost base. In addition, we finalized our insurance claim related to the 2022 Grass Valley facility fire, securing a $9.5 million non-dilutive settlement at a critical point in our transition.”

“As we move through 2026, we are executing with a clear strategic growth focus, supported by a strengthened financial and operational foundation. Our priorities include expanding VLN® retail distribution and consumer awareness, scaling toward profitability, and maintaining active engagement with FDA regulators and public health stakeholders both domestically and internationally.”

Fourth Quarter 2025 Financial Results (compared to Third Quarter 2025, except as noted)

All figures reported below reflect continuing operations, excluding discontinued operations related to the sale and exit of the Company’s hemp/cannabis business in late 2023, except as noted.

  • Net revenues decreased slightly to $3.5 million from $4.0 million.
  • Gross profit (loss) improved to $(0.8) million, compared to $(1.1) million.
  • Operating expenses were $2.0 million, decreased from $2.2 million.
  • Operating loss decreased to $2.8 million, compared to $3.2 million.
  • Net loss was $2.8 million, compared to net loss of $3.8 million.
  • Adjusted EBITDA loss was $2.4 million, compared to a loss of $2.9 million.
  • Ended the calendar year 2025 with cash of $7.1 million.

Recent Business Highlights

  • Maintained a strong balance sheet, ending the year with no outstanding debt and $7.1 million in cash available for operations.
  • Continued to expand market access to both VLN® and Partner VLN® products, as well as new natural style cigarette products, with expanded store availability
  • Further increased state authorizations to support expanded access to the Company’s branded products, including:
    • 22nd Century VLN® – 48 States
    • Pinnacle® VLN® – 42 States
    • Pinnacle® – 45 States
    • Smoker Friendly VLN® – 43 States
    • Smoker Friendly – 47 States
    • Smoker Friendly Black Label (Tobacco & Water) – 39 states
  • Increased Pinnacle® VLN® availability to almost 1,500 stores within a top-5 convenience store chain across 12 states; full rollout across all remaining store locations is expected in next 90 days supported by in-store marketing materials and digital promotion programs.
  • Continued to advance negotiations with new customers to expand VLN® distribution and launch additional VLN® partner brands, further diversifying the reduced nicotine content product category.
  • Continued to advance initiatives aimed at margin expansion through mix improvement, operating cost efficiency and capital allocation.
  • Moved forward on plans to introduce 100mm format VLN® cigarettes and additional international combustible products tailored to consumer preferences in those markets.

Fourth Quarter 2025 Product Line Net Revenues

  • Cigarette net revenues were $2.6 million, increased from $2.5 million in the third quarter of 2025, reflecting an increase in certain customer pricing incentives, offset by increased CMO volumes. Additional expansion of new natural style cigarette products launched in 2025 will continue to accelerate revenue and margin growth in this category.
  • Filtered cigar net revenues were $0.4 million compared to $1.3 million, reflecting ongoing shifting product mix and decreasing volume from remaining CMO customers.
  • Distribution net revenues from other tobacco products, consisting of Pinnacle branded moist snuff and cigarillos were $0.4 million compared to negligible amounts in the third quarter 2025.
  • VLN® cigarette net revenues were $0.1 million, reflecting continuing placements of VLN® and partner VLN® products, offset by customer returns and product exchanges to the new VLN® branding. Total new branded VLN® and partner VLN® products shipped in the fourth quarter were approximately 8,800 cartons.

Balance Sheet

  • The Company reported zero long-term debt, having extinguished its remaining senior secured debt in full during 2025.
  • Cash and equivalents were $7.1 million at quarter end.
  • Inventories were $4.3 million, increased from $2.9 million at third quarter end, reflecting increases in reduced nicotine content tobacco leaf.

Conference Call
22nd Century will host a live webcast today at 8:00 a.m. E.T. to discuss its fourth quarter and full year 2025 financial results and business highlights. The live and archived webcast will be accessible in the Events section on 22nd Century’s Investor Relations website at https://ir.xxiicentury.com/events.

Summary Financial Results
(dollars in thousands, except per share data)

  Three Months Ended
  December 31,  Change
  2025  2024  $%
Revenues, net $3,537  $4,020  (483)(12.0)
Gross loss $(834) $(1,254) 420 (33.5)
Operating loss $(2,803) $(4,091) 1,288 (31.5)
Net loss from continuing operations $(2,783) $(4,246) 1,463 (34.5)
Basic and diluted loss per common share from continuing operations $(5.89) $(3,257.47) 3,251.58 (99.8)
Adjusted EBITDA (a) $(2,387) $(3,888) 1,501 38.6 


  Year Ended
  December 31,  Change
  2025  2024  $%
Revenues, net $17,587  $24,382  (6,795)(27.9)
Gross loss $(3,137) $(2,400) (737)30.7 
Operating loss $(11,566) $(13,950) 2,384 (17.1)
Net loss from continuing operations $(13,117) $(15,495) 2,378 (15.3)
Basic and diluted loss per common share from continuing operations $(71.26) $(27,812.56) 27,741.30 (99.7)
Adjusted EBITDA (a) $(10,233) $(13,137) 2,904 22.1 
          
(a) Adjusted EBITDA is a non-GAAP financial measure. Please see “Notes Regarding Non-GAAP Financial Information” for additional information regarding our use of non-GAAP financial measures. Refer to Tables A at the end of this release for reconciliations of adjusted amounts to the closest corresponding GAAP financial measures.


Summary Product Line Results

(in thousands)

  Three Months Ended
  December 31,    
  2025 2024  Change
  $Cartons $Cartons $Cartons
Contract manufacturing         
Cigarettes 2,648155 3,276 228  (628)(73)
Filtered cigars 40651 833 112  (427)(61)
Other tobacco products 35440 - -  354 40 
Total contract manufacturing 3,408246 4,109 340  (701)(94)
VLN® 1292 (89)(2) 218 4 
Total product line revenues 3,537248 4,020 338  (483)(90)


  Year Ended
  December 31,    
  2025 2024 Change
  $Cartons $Cartons $Cartons
Contract manufacturing         
Cigarettes 12,8971,525 14,219 644 (1,322)881 
Filtered cigars 4,110549 9,427 1,361 (5,317)(812)
Other tobacco products 44254 756 120 (314)(66)
Total contract manufacturing 17,4492,128 24,402 2,125 (6,953)3 
VLN® 1384 (20)- 158 4 
Total product line revenues 17,5872,132 24,382 2,125 (6,795)7 


About 22nd Century Group, Inc.

22nd Century Group is pioneering the tobacco harm reduction movement by enabling smokers to take control of their nicotine consumption.

Our Technology is Tobacco
Our proprietary non-GMO reduced nicotine tobacco plants were developed using our patented technologies that regulate alkaloid biosynthesis activities resulting in a tobacco plant that contains 95% less nicotine than traditional tobacco plants. Our extensive patent portfolio has been developed to ensure that our high-quality tobacco can be grown commercially at scale. We continue to develop our intellectual property to ensure our ongoing leadership in the tobacco harm reduction movement.

Our Products
We created our flagship product, the VLN® cigarette using our low nicotine tobacco, to give traditional cigarette smokers an authentic and familiar alternative in the form of a combustible cigarette that helps them take control of their nicotine consumption. VLN® cigarettes have 95% less nicotine compared to traditional cigarettes and have been proven to allow consumers to greatly reduce their nicotine consumption.

FDA Authorization and Scientific Foundation
VLN® low nicotine combustible cigarettes were authorized in December 2021, making them the first and still the only combustible cigarettes authorized by the U.S. Food and Drug Administration specifically to help reduce nicotine consumption.

Decades of independent clinical research and peer-reviewed studies—evaluated as part of the FDA’s Modified Risk Tobacco Product (MRTP) authorization process—demonstrated that reducing nicotine content can decrease nicotine intake, increase quit attempts, and reduce overall exposure to nicotine.

FDA-authorized VLN® claims include:

  • 95% less nicotine”
  • “Helps reduce your nicotine consumption”
  • “Greatly reduces your nicotine consumption”
  • “Helps you smoke less”

VLN® and Helps You Smoke Less® are registered trademarks of 22nd Century Limited LLC.

Learn more at xxiicentury.com, on X (formerly Twitter), on LinkedIn, and on YouTube.

Learn more about VLN® at tryvln.com.

Cautionary Note Regarding Forward-Looking Statements
Except for historical information, all of the statements, expectations, and assumptions contained in this press release are forward-looking statements, including but not limited to our full year business outlook. Forward-looking statements typically contain terms such as “anticipate,” “believe,” “consider,” “continue,” “could,” “estimate,” “expect,” “explore,” “foresee,” “goal,” “guidance,” “intend,” “likely,” “may,” “plan,” “potential,” “predict,” “preliminary,” “probable,” “project,” “promising,” “seek,” “should,” “will,” “would,” and similar expressions. Forward-looking statements include, but are not limited to, statements regarding (i) our cost reduction initiatives, (ii) our expectations regarding regulatory enforcement, including our ability to receive an exemption from new regulations, and (iii) our financial and operating performance. Actual results might differ materially from those explicit or implicit in forward-looking statements. Important factors that could cause actual results to differ materially are set forth in “Risk Factors” in the Company’s Annual Report on Form 10-K filed on March 26, 2026. All information provided in this release is as of the date hereof, and the Company assumes no obligation to and does not intend to update these forward-looking statements, except as required by law.

Notes regarding Non-GAAP Financial Information
In addition to the Company’s reported results in accordance with generally accepted accounting principles in the United States of America (“GAAP”), the Company provides EBITDA and Adjusted EBITDA.

In order to calculate EBITDA, the Company adjusts net (loss) income by adding back interest expense (income), provision (benefit) for income taxes, and depreciation and amortization expense. Adjusted EBITDA consists of EBITDA adjusted by the Company for certain non-cash and/or non-operating expenses, including adding back equity-based employee compensation expense, restructuring and restructuring-related charges such as impairment, acquisition and transaction costs, and other unusual or infrequently occurring items, if applicable, such as inventory reserves and adjustments, gains or losses on disposal of property, plant and equipment, and gains or losses on investments.

The Company believes that the presentation of EBITDA and Adjusted EBITDA are important financial measures that supplement discussion and analysis of its financial condition and results of operations and enhances an understanding of its operating performance. While management considers EBITDA and Adjusted EBITDA to be important, these financial performance measures should be considered in addition to, but not as a substitute for or superior to, other measures of financial performance prepared in accordance with GAAP, such as operating (loss) income, net (loss) income and cash flows from operations. Adjusted EBITDA is susceptible to varying calculations and the Company’s measurement of Adjusted EBITDA may not be comparable to those of other companies.

Investor Relations & Media Contact
Matt Kreps
Investor Relations
22nd Century Group
investorrelations@xxiicentury.com
214-597-8200

22nd CENTURY GROUP, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited)
(amounts in thousands, except share and per-share data)

  December 31,  December 31, 
  2025  2024 
ASSETS      
Current assets:      
Cash and cash equivalents $7,149  $4,422 
Accounts receivable, net  3,594   1,698 
Inventories  4,326   2,015 
Insurance recoveries     768 
GVB promissory note, net     500 
Prepaid expenses and other current assets  2,562   1,068 
Current assets of discontinued operations held for sale     1,051 
Total current assets  17,631   11,522 
Property, plant and equipment, net  2,440   2,773 
Operating lease right-of-use assets, net  728   1,639 
Intangible assets, net  6,224   5,724 
Other assets     15 
Total assets $27,023  $21,673 
       
LIABILITIES, MEZZANINE EQUITY AND SHAREHOLDERS' EQUITY      
Current liabilities:      
Notes and loans payable-current $204  $254 
Current portion of long-term debt     1,500 
Operating lease obligations  168   261 
Accounts payable  1,000   2,401 
Accrued expenses and other current liabilities  836   1,439 
Accrued litigation     768 
Accrued excise taxes and fees  3,343   2,038 
Contract liabilities  1,721   20 
Current liabilities of discontinued operations held for sale     1,281 
Total current liabilities  7,272   9,962 
Long-term liabilities:      
Notes and loans payable  504    
Operating lease obligations  601   1,437 
Long-term debt     5,165 
Other long-term liabilities  154   1,097 
Total liabilities  8,531   17,661 
       
Mezzanine equity:      
Series A convertible preferred shares, $0.00001 par value; 10,000,000 shares authorized, 9,650 shares issued and outstanding at December 31, 2025 and 0 at December 31, 2024, respectively  2,734    
Total mezzanine equity  2,734    
       
Shareholders' equity:      
Common stock, $.00001 par value, 500,000,000 shares authorized, 510,384 shares issued and outstanding at December 31, 2025 and 2,285 at December 31, 2024, respectively      
Common stock, par value      
Capital in excess of par value  414,683   397,883 
Accumulated deficit  (398,925)  (393,871)
Total shareholders' equity  15,758   4,012 
Total liabilities, mezzanine equity and shareholders’ equity $27,023  $21,673 


22nd CENTURY GROUP, INC.

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
(Unaudited)
(amounts in thousands, except share and per-share data)

 Year Ended
 December 31, 
 2025  2024 
Revenues, net$17,587  $24,382 
Cost of goods sold 10,186   14,278 
Excise taxes and fees on products 10,538   12,504 
Gross loss (3,137)  (2,400)
Operating expenses:     
Sales, general and administrative 7,591   10,287 
Research and development 688   1,133 
Other operating expense, net 150   130 
Total operating expenses 8,429   11,550 
Operating loss from continuing operations (11,566)  (13,950)
Other income (expense):     
Other income (expense), net (207)  507 
Interest income 83   72 
Interest expense (1,455)  (2,094)
Total other income (expense), net (1,579)  (1,515)
Loss from continuing operations before income taxes (13,145)  (15,465)
(Benefit) provision for income taxes (28)  30 
Net loss from continuing operations$(13,117) $(15,495)
      
Discontinued operations:     
Income from discontinued operations before income taxes$8,063  $331 
Provision for income taxes     
Income from discontinued operations$8,063  $331 
      
Net loss$(5,054) $(15,164)
Comprehensive loss$(5,054) $(15,164)
      
Net loss$(5,054) $(15,164)
Deemed dividends (4,679)  (10,303)
Net loss available to common shareholders$(9,733) $(25,467)
      
Basic and diluted income (loss) per share:     
Basic and diluted loss per common share from continuing operations$(71.26) $(27,812.56)
Basic and diluted income per common share from discontinued operations$43.81  $594.83 
Basic and diluted loss per common share from deemed dividends$(25.42) $(18,493.32)
Basic and diluted loss per common share$(52.87) $(45,711.05)
      
Weighted average shares outstanding - basic and diluted 184,067   557 


Table A – Reconciliations of Non-GAAP Measures

(dollars in thousands, except share and per-share data)

Below is a table containing information relating to the Company’s Net loss, EBITDA and Adjusted EBITDA for the years ended December 31, 2025 and 2024, including a reconciliation of these Non-GAAP measures for such periods.

  Quarter Ended
  December 31, 
  Amounts in thousands ($000's)
  except share and per share data
  (UNAUDITED)
         $ Change 
  2025  2024   fav / (unfav)1
Net loss from continuing operations $ (2,783) $ (4,246) $ 1,463 
Interest (income)/expense, net  (25)  221   (246)
Provision (benefit) for income taxes  5   3   2 
Amortization and depreciation  218   241   (23)
EBITDA $ (2,585) $ (3,781) $ 1,196 
Adjustments:         
Restructuring and impairment     (111)  111 
Change in fair value of derivative liabilities     (75)  75 
Change in fair value of warrant liabilities     (68)  68 
Equity-based employee compensation expense  198   147   51 
Adjusted EBITDA $ (2,387) $ (3,888) $ 1,501 
          
Adjusted EBITDA loss per common share $(5.05) $(2,982.89) $2,977.84 
Weighted average common shares outstanding - basic and diluted  472,290   1,304    


  Year Ended
  December 31, 
  Amounts in thousands ($000's)
  except share and per share data
  (UNAUDITED)
         $ Change 
  2025  2024   fav / (unfav)1
Net loss from continuing operations $ (13,117) $ (15,495) $ 2,378 
Interest (income)/expense, net  1,372   2,022   (650)
Provision (benefit) for income taxes  (28)  30   (58)
Amortization and depreciation  912   1,003   (91)
EBITDA $ (10,861) $ (12,440) $ 1,579 
Adjustments:         
Restructuring and impairment     (459)  459 
Inventory write-down     431   (431)
Change in fair value of derivative liabilities     (557)  557 
Change in fair value of warrant liabilities  207   (492)  699 
Equity-based employee compensation expense  421   380   41 
Adjusted EBITDA $ (10,233) $ (13,137) $ 2,904 
          
Adjusted EBITDA loss per common share $(55.59) $(23,580.59) $23,525.00 
Weighted average common shares outstanding - basic and diluted  184,067   557    


1
Fav = Favorable variance, which increases EBITDA and Adjusted EBITDA; Unfav = unfavorable variance, which reduces EBITDA and Adjusted EBITDA


FAQ

What were 22nd Century (XXII) Q4 2025 revenues and net loss?

Q4 2025 revenue was $3.5 million and net loss was $2.8 million. According to the company, those figures reflect continuing operations excluding the prior hemp business, with slightly lower revenues versus Q3 and improved gross loss and operating expense trends.

How much cash and debt did 22nd Century (XXII) report at year-end 2025?

22nd Century exited 2025 debt-free with $7.1 million cash. According to the company, this follows repayment and settlements that eliminated legacy debt and was supported by a $9.5 million insurance recovery tied to a prior facility loss.

What were 22nd Century's (XXII) full-year 2025 revenue and adjusted EBITDA results?

Full-year 2025 revenue was $17.6 million and adjusted EBITDA loss was $10.2 million. According to the company, revenues fell 27.9% year-over-year while adjusted EBITDA loss improved versus the prior year.

How broadly available are VLN® products after 22nd Century's 2025 expansion?

Company VLN® authorization reached 48 states

What operational progress did 22nd Century (XXII) report on product shipments and inventory in Q4 2025?

Q4 shipped roughly 8,800 cartons of new VLN® and partner products; inventory rose to $4.3M. According to the company, inventory increases reflect higher reduced‑nicotine tobacco leaf and continued placements alongside customer returns and brand transition activity.
22Nd Century

NASDAQ:XXII

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1.50M
493.29k
Tobacco
Cigarettes
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United States
WILLIAMSVILLE