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YD Bio Announces Peer-Reviewed Publication in Nutrients, Co-Authored with Physicians from the Taiwan Chronic Disease Healthcare Association and the Future Health Institute

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YD Bio (Nasdaq: YDES) announced that a peer-reviewed review article titled “Beyond Bone Health: Exploring the ‘Heart–Brain–Bone’ Axis Modulated by Lipid-Soluble Nutrients (Omega-3, Vitamin D3, and Vitamin K2)” has been published open access in Nutrients, an MDPI journal. The paper, accepted on August 18, 2026 and published August 19, 2026, was co-authored by YD Bio’s scientific team and physicians from the Taiwan Chronic Disease Healthcare Association, the Future Health Institute, and Taipei Medical University Hospital. The article synthesizes evidence on how omega-3 fatty acids, vitamin D3 and vitamin K2 may influence shared pathways across cardiovascular, central nervous and skeletal systems, and it formalizes a research component within YD Bio’s recently announced physician-partnership and nutraceutical initiative in Taiwan.

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Positive

  • None.

Negative

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Market Context

YD Bio’s recent news record included 9.74%, 0.87%, and 0.44% 24-hour reactions, alongside -7.69% and...
Analysis

YD Bio’s recent news record included 9.74%, 0.87%, and 0.44% 24-hour reactions, alongside -7.69% and -17.75% declines. That mixed history places this research milestone alongside a risk: commercial results were not reported.

Key Figures

Announcement date: August 25, 2026 Prior initiative date: August 11, 2026 Nutraceutical products: 2 products +3 more
6 metrics
Announcement date August 25, 2026 YD Bio publication announcement
Prior initiative date August 11, 2026 Earlier physician-partnership announcement
Nutraceutical products 2 products Launched in Taiwan with physician collaborators
Manuscript acceptance August 18, 2026 Peer-reviewed manuscript acceptance date
Journal citation Nutrients 2026, 18(16), 2711 Published open-access article citation
Conditions in framework 3 conditions Cardiovascular disease, neurocognitive decline and osteoporotic bone loss

Historical Context

5 past events · Latest: Aug 11 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Aug 11 Partnership initiative Positive +9.7% Launched physician-partnership initiative with two nutraceutical products in Taiwan alongside CDHA and FHI
Aug 04 Research publication Positive +0.9% Highlighted a computational framework for keratoconus research with Taipei Medical University collaborators
Jul 28 Cancer testing pilot Positive +0.4% Launched six-month Canadian pilot capped at up to 50 patient episodes
Jul 23 Conference exhibition Positive -7.7% Showcased ophthalmology, oncology diagnostics and clinical services at BIO Asia-Taiwan
Jul 02 Laboratory expansion Positive -17.8% Secured Rhode Island and Pennsylvania licenses, expanding authorized operations to 46 states

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news reactions were positive after the three most recent announcements but negative after the two earlier operational or exhibition updates.

Key Terms

dna methylation, laboratory-developed test, cholecalciferol, menaquinone-7
4 terms
dna methylation technical
"a biotechnology company advancing DNA methylation–based cancer detection technology"
A chemical tag added to DNA that acts like a sticky note on a recipe, changing whether a gene is read without altering the underlying genetic code. For investors, DNA methylation matters because these tags can serve as measurable biomarkers for disease diagnosis, risk prediction, and treatment response, and they can be targets for drugs or diagnostic tests—factors that influence clinical value, regulatory approval, and market potential.
laboratory-developed test regulatory
"oncology testing programs in the United States under a laboratory-developed test strategy"
A laboratory-developed test is a diagnostic test that a single clinical laboratory designs, builds and uses in its own facility rather than buying from an outside manufacturer; think of it as a custom recipe made and run in-house for diagnosing disease. Investors care because these tests can be quicker to bring to market and create a revenue stream for labs, but they also carry regulatory and quality-risk differences that can affect demand, reimbursement and legal exposure.
cholecalciferol medical
"vitamin D3 (cholecalciferol) and vitamin K2"
Cholecalciferol is the chemical name for vitamin D3, a fat‑soluble nutrient the body makes in skin after sun exposure and that is also sold as a supplement or formulated into medicines. As a raw ingredient it matters to investors because its classification, purity, dosing and label claims determine whether a product is regulated as a dietary supplement or a drug, affect manufacturing and quality controls, and influence market demand like any essential input in a recipe.
menaquinone-7 medical
"vitamin K2 (menaquinone-7, MK-7) act on shared biological pathways"
Menaquinone-7 (often called MK-7) is a specific chemical form of vitamin K2 used in dietary supplements and some medical products; it helps the body move calcium into bones and away from blood vessels. Investors encounter the term when assessing companies that make supplements, ingredient suppliers, or drug developers because MK-7 affects product claims, manufacturing standards, labeling rules, and market demand — like a recognizable ingredient on a product’s spec sheet.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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TAIPEI, Taiwan, Aug. 25, 2026 (GLOBE NEWSWIRE) -- YD Bio Limited (“YD Bio” or the “Company”) (Nasdaq: YDES), a biotechnology company advancing DNA methylation–based cancer detection technology and ophthalmologic innovations, today announced the publication of a peer-reviewed review article in Nutrients, an international open-access journal published by MDPI (Multidisciplinary Digital Publishing Institute). The article, titled “Beyond Bone Health: Exploring the ‘Heart–Brain–Bone’ Axis Modulated by Lipid-Soluble Nutrients (Omega-3, Vitamin D3, and Vitamin K2),” was co-authored by members of the Company’s scientific team together with physicians associated with the Taiwan Chronic Disease Healthcare Association (“CDHA”), the Future Health Institute (“FHI”), and the Department of Neurosurgery at Taipei Medical University Hospital, among others.

On August 11, 2026, YD Bio previously announced a physician-partnership initiative, along with the launch of two nutraceutical products in Taiwan in collaboration with the Taiwan CDHA and FHI. This announcement reflects an expansion of the initiative to include peer-reviewed research. The Company disclosed at the time that a manuscript co-authored by YD Bio personnel and physician collaborators had been submitted to a peer-reviewed journal and was under review. The manuscript was accepted on August 18, 2026 and published the following day in Nutrients as the article described in this announcement.

Publication Highlights

  • Published open access in Nutrients (MDPI) — Nutrients 2026, 18(16), 2711; https://doi.org/10.3390/nu18162711.
  • Assembles and grades available evidence on how long-chain omega-3 polyunsaturated fatty acids (EPA/DHA), vitamin D3 (cholecalciferol) and vitamin K2 (menaquinone-7, MK-7) act on shared biological pathways involving calcium trafficking, inflammation resolution and vascular integrity across the cardiovascular, central nervous and skeletal systems.
  • Explores the “Heart–Brain–Bone” axis as an integrative framework connecting three major conditions associated with aging — cardiovascular disease, neurocognitive decline and osteoporotic bone loss — which have historically been investigated and managed across separate clinical disciplines.
  • Brings together expertise across clinical medicine, neurosurgery, and industry, with the Company’s scientific team contributing to peer-reviewed research alongside physician collaborators in healthcare areas relevant to its consumer health business.

From Physician Collaboration to Peer-Reviewed Science

YD Bio’s physician-partnership model is built on practicing clinicians defining formulation requirements based on observations from their own patient populations, with the Company contributing product development, sourcing, quality oversight and commercialization.

This publication adds a peer-reviewed research component to the model, expanding the scope of collaboration between physician partners and YD Bio’s scientific team.

The Company believes that this approach can connect clinical observations, scientific research, and consumer health product development, while providing a framework for future collaborations with other physicians and healthcare organizations.

As YD Bio expands its physician-partnership initiative, the Company intends to continue supporting scientific and peer-reviewed work alongside its current and future clinician partners.

“When we announced our physician-partnership initiative earlier this month, we indicated that the underlying science was undergoing peer review.” said Dr. Ethan Shen, Founder, Chairman and Chief Executive Officer of YD Bio. “The publication of this article is an important milestone in our process. We believe a consumer health business built alongside practicing physicians should be supported not only by clinical experience and product development capabilities, but also by scientific rigor and accompanying literature. We intend to continue working this way as we expand our physician-partnership model to additional healthcare professionals and organizations.”

About YD Bio Limited

YD Bio is a U.S.-anchored public biotechnology company building an integrated healthcare platform spanning regulated molecular diagnostics, clinical services, precision medicine, and life science commercialization. The Company operates DNA methylation–based oncology testing programs in the United States under a laboratory-developed test strategy and supports pharmaceutical and biotechnology partners through compliant life science distribution and clinical trial supply chain services. In addition, the Company maintains regulated ocular health commercialization operations and a consumer health distribution platform in Asia. For more information, visit ir.ydesgroup.com and follow the Company on Facebook, X, Threads, Instagram and LinkedIn.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are intended to be covered by the safe harbor provisions created by the U.S. Private Securities Litigation Reform Act of 1995, including statements regarding the Company’s intention to support further peer-reviewed work alongside clinician partners and to expand its physician-partnership model, and the anticipated benefits of such approach. Forward-looking statements are not guarantees of future performance and can be identified by words such as “aim,” “intend,” “seek,” “believe,” “designed to,” “expects,” “anticipates,” “plans,” “may,” “could,” “will” and other similar expressions. The article described above is a narrative review of published literature; it reports no new experimental or clinical data and does not establish the clinical safety or efficacy of any product. Actual results may differ materially from those expressed or implied due to a variety of factors, including consumer demand and market acceptance; the Company’s ability to enter into and maintain partnerships with physicians and other healthcare organizations; competition; regulatory and labeling requirements in Taiwan and other jurisdictions; and other risks and uncertainties described in YD Bio’s filings with the U.S. Securities and Exchange Commission. The Company cautions investors not to place undue reliance on such forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to update any forward-looking statements, except as required by law, and encourages investors to review the risk factors in its Annual Report on Form 20-F and other SEC filings.

For investor and media inquiries, please contact:

YD Bio Limited
Investor Relations
Email: investor@ydesgroup.com

WFS Investor Relations Inc.
Email: services@wfsir.com
Phone: +1 628 283 9214


FAQ

What did YD Bio (NASDAQ:YDES) announce on August 25, 2026?

YD Bio announced publication of a peer-reviewed review article in the journal Nutrients. According to YD Bio, the paper was co-authored with Taiwanese physician collaborators and examines how omega-3, vitamin D3 and vitamin K2 may affect cardiovascular, brain and bone health through shared biological pathways.

What is the focus of YD Bio’s Nutrients article on omega-3, vitamin D3 and vitamin K2?

The article reviews evidence on how omega-3, vitamin D3 and vitamin K2 act on shared pathways affecting calcium trafficking, inflammation and vascular integrity. According to YD Bio, it frames these nutrients within a “Heart–Brain–Bone” axis linking cardiovascular disease, neurocognitive decline and osteoporotic bone loss.

How does the Nutrients publication relate to YD Bio’s physician-partnership initiative announced for YDES shareholders?

The publication adds a peer-reviewed research layer to YD Bio’s physician-partnership model. According to YD Bio, practicing clinicians define nutraceutical formulations, while the company contributes development and commercialization, and now supports scientific articles co-authored with physicians to connect clinical observations with consumer health product development.

Which institutions collaborated with YD Bio on the Nutrients review article mentioned in the YDES news?

The review was co-authored with physicians from the Taiwan Chronic Disease Healthcare Association, the Future Health Institute and Taipei Medical University Hospital. According to YD Bio, these collaborators contributed clinical perspectives that complement the company’s scientific team in areas relevant to its consumer health business in Asia.

What does the published Heart–Brain–Bone axis research mean for YD Bio’s consumer health strategy?

The research supports YD Bio’s consumer health approach with peer-reviewed literature on omega-3, vitamin D3 and vitamin K2. According to YD Bio, integrating clinician input, scientific review and product development may guide future nutraceutical offerings and collaborations with additional physicians and healthcare organizations.

When was YD Bio’s Nutrients article on the Heart–Brain–Bone axis accepted and published?

The manuscript was accepted on August 18, 2026 and published on August 19, 2026 in Nutrients. According to YD Bio, this timing follows its August 11, 2026 announcement of a physician-partnership initiative and related nutraceutical product launches in Taiwan.