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Illumina (ILMN) Stock Price, News & Analysis

ILMN NASDAQ
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Price Move History

Daily moves over 5%
23 252 sessions, November 5, 2025 to November 5, 2026
Largest daily move
-18.6% close of October 30, 2026
1-year change
+69.9% closing prices, November 5, 2025 to November 5, 2026
1-month change
-29.2% closing prices, October 5, 2026 to November 5, 2026

Company Description

Illumina, Inc. (NASDAQ: ILMN) operates in the analytical laboratory instrument manufacturing industry and is widely described as a global leader in DNA sequencing and array-based technologies. According to the company’s own statements in multiple press releases, Illumina focuses on improving human health by unlocking the power of the genome and serves customers across research, clinical, and applied markets.

Illumina states that its products and technologies are used in life sciences, oncology, reproductive health, agriculture, and other emerging segments. Illumina Inc provides tools and services to analyze genetic material, and Illumina generates a substantial portion of its revenue from sequencing instruments, consumables, and services. Illumina’s high-throughput technology enables whole genome sequencing in humans and other large organisms, while lower-throughput tools support applications that require smaller data outputs, such as certain screening uses. Illumina also sells microarrays that enable focused genetic screening for consumer and agricultural applications.

Core business and technology focus

Illumina’s business centers on DNA sequencing and array-based technologies that support genomic and multiomic research. Company descriptions in recent news releases emphasize that Illumina is building foundational technologies and datasets for genomics, including single-cell and multiomic analysis, and that its platforms are used by customers in research laboratories, clinical environments, and applied markets.

Illumina historically has generated more than 90% of its revenue from sequencing instruments, consumables, and services, with microarrays accounting for a smaller share. Illumina has a business model built around instrument placement and the ongoing use of consumables and associated services for genomic analysis.

Applications across research, clinical, and applied markets

In company press releases, Illumina explains that its technologies are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. Examples cited by Illumina include use in cancer research and oncology, reproductive and preventive health, and agricultural and population-scale studies. The company also notes that it partners with biopharma, academic institutions, and population health programs to generate large genomic and proteomic datasets.

Illumina’s recent initiatives underscore its role in enabling precision medicine and drug discovery. In its announcement of the Illumina Billion Cell Atlas, the company describes building a large genome-wide genetic perturbation dataset intended to accelerate drug discovery through AI across the pharmaceutical ecosystem. The Atlas is designed to help validate genetic targets, train AI models at scale, and advance research into disease mechanisms across immune disorders, cancer, cardiometabolic, neurological, and rare genetic diseases.

Multiomics, AI, and data products

Illumina’s news releases describe a growing focus on multiomics and AI-enabled analysis. The company has introduced Illumina Connected Multiomics, a cloud-based research software platform to analyze and visualize multiomic and multimodal biological data at scale. According to Illumina, this platform integrates data across transcriptomics, genomics, proteomics, epigenetics, and other modalities, and uses integrated DRAGEN secondary analysis and AI-enabled variant interpretation tools such as PrimateAI and PromoterAI to highlight biologically meaningful signals.

Illumina has also launched its BioInsight business, which the company describes as providing foundational technologies and datasets to power the next generation of drug discovery and AI in pharma. The Illumina Billion Cell Atlas is identified as the first data product from BioInsight, built using Illumina’s single-cell RNA preparation platform and processed through the DRAGEN pipeline and Illumina Connected Analytics cloud platform.

Proteomics and expansion into the proteomics market

Illumina is expanding into proteomics, as detailed in company news about Illumina Protein Prep. The company states that Illumina Protein Prep delivers broad coverage of the blood proteome and is being used by customers ranging from academic institutions to large national biobanks. Illumina positions Protein Prep as a way to integrate comprehensive proteomics into large-scale genomics studies, enriching datasets for diseases such as cancer and cardiometabolic and immunologic conditions.

Illumina further notes that it is acquiring Standard BioTools’ aptamer-based and functional proteomics business, including SomaLogic, under a Stock Purchase Agreement described in a Form 8-K filing. The company states that this acquisition will add aptamer-based and functional proteomics capabilities, subject to regulatory approvals and customary closing conditions.

Strategic collaborations and partnerships

Illumina’s press releases highlight collaborations with major pharmaceutical and genomics companies. For the Billion Cell Atlas, Illumina describes an alliance framework with AstraZeneca, Merck, and Eli Lilly and Company as founding participants, with the goal of using large-scale cell perturbation data to validate drug targets and train AI models. Another release details a collaboration and strategic investment with MyOme, a genomics innovation and risk modeling company, aimed at advancing whole-genome sequencing combined with AI-integrated risk models for common, chronic conditions, cancers, and rare diseases.

These collaborations illustrate Illumina’s role as a technology and data provider to biopharma, clinical genomics, and population health initiatives, leveraging its sequencing platforms, proteomics solutions, and AI-enabled analytics.

Capital markets and regulatory filings

Illumina’s common stock, with a par value of $0.01 per share, trades on The Nasdaq Stock Market LLC under the symbol ILMN, as disclosed in multiple Form 8-K filings. The company is incorporated in Delaware, with a stated jurisdiction of incorporation of Delaware and an employer identification number listed in its SEC filings. Recent 8-K filings describe periodic financial results announcements, preliminary unaudited results, and capital markets transactions, including the issuance of 4.750% notes due 2030 under an existing indenture.

In an 8-K dated November 25, 2025, Illumina reports the completion of a public offering of notes and states that it expects to use the net proceeds for general corporate purposes, which may include repayment of existing notes and completion of the proposed SomaLogic acquisition. Another 8-K dated June 22, 2025 outlines the Stock Purchase Agreement to acquire SomaLogic and related entities, including details on the purchase price, potential milestone payments, and regulatory approval conditions.

Company status and sector classification

Based on the most recent SEC filings and press releases provided, Illumina remains an active public company with securities registered under Section 12(b) of the Exchange Act and trading on Nasdaq under the symbol ILMN. The company is classified in the analytical laboratory instrument manufacturing industry within the broader manufacturing sector, and its disclosures emphasize its role in genomics, multiomics, and proteomics technologies.

Use cases for investors and researchers

For investors, Illumina represents a company whose business is closely tied to the adoption and expansion of genomic, multiomic, and proteomic technologies in research, clinical, and applied markets. Its SEC filings provide details on financial performance, capital structure, and material agreements, while its press releases describe product launches, collaborations, and strategic initiatives in sequencing, multiomics software, proteomics, and AI-enabled data products.

For researchers and industry participants, Illumina’s platforms and datasets, such as Illumina Connected Multiomics, DRAGEN pipelines, Illumina Protein Prep, and the Billion Cell Atlas, are positioned by the company as tools to accelerate discovery, support precision medicine, and enable large-scale studies across diverse diseases and populations.

Stock Performance

$213.10
+2.45%
+5.10
Last updated: November 6, 2026 at 10:39
+69.9%
Performance 1 year
$32.2B

Illumina (ILMN) closed at $208.00 on November 5, 2026. Over the past 12 months, the price has gained 69.9%.

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ILMN Metrics & Rankings

Price returns through November 5, 2026. Month and year figures include the first trading day. Ranking links may use different dates.

SEC Filings

Illumina has filed 10 recent SEC filings, including 3 Form 4, 2 Form SCHEDULE 13G/A, 2 Form 8-K, 1 Form 144. The most recent filing was submitted on . SEC filings provide transparency into a company's financial condition, material events, and regulatory compliance. View all ILMN SEC filings →

Insider Radar

Net Sellers
90-Day Summary
0
Shares Bought
1,601,541
Shares Sold
67
Transactions
Most Recent Transaction
Meister Keith A. (Director) sold 50,000 shares held indirectly at an average of $227.17 on November 4, 2026

Insider selling at Illumina over the past 90 days can reflect routine portfolio management, scheduled trading plans (Rule 10b5-1), tax planning, or compensation-related dispositions rather than a directional view on the stock.

Based on SEC Form 4 filings over the last 90 days.

Financial Highlights

Illumina generated $4.3B in revenue in FY2025, retaining a 66.1% gross margin, operating income reached $807.0M (18.6% operating margin), and net income was $850.0M, reflecting a 19.6% net profit margin. Diluted earnings per share stood at $5.45. The company generated $1.1B in operating cash flow. The current ratio was 2.08, measuring current assets divided by current liabilities.

$4.3B
Revenue (FY2025)
$850.0M
Net Income (FY2025)
$1.1B
Operating Cash Flow

Upcoming Events

NOV
10
November 10, 2026 Marketing

UBS Fireside Chat

Fireside chat at UBS Global Healthcare Conference Nov 10, 2026 at 07:15 PT. Webcast investor.illumina.com; replay for 30 days.
NOV
17
November 17, 2026 Marketing

Jefferies Healthcare Chat

Fireside chat at Jefferies Global Healthcare Conference; webcast at investor.illumina.com. Replay archived 30 days.
YEAR
2027
2027 Product

FFPE version customer enablement

Initial customer enablement of FFPE-focused StrataMap targeted for 2027; commercial timing, availability and access to follow.
YEAR
2027
2027 Product

Global MRD solution launch

Global commercial launch of Illumina's NovaSeq-compatible MRD research solution; timing within next calendar year; details TBA

Illumina has 4 upcoming scheduled events. The next event, "UBS Fireside Chat", is scheduled for November 10, 2026 (in 4 days). Investors can track these dates to stay informed about potential catalysts that may affect the ILMN stock price.

Short Interest History

Last 12 Months

Short interest in Illumina (ILMN) currently stands at 7.9 million shares, down 16.8% from the previous reporting period, representing 5.2% of the float. Since November 2025, short interest has increased by 20.5%.

Days to Cover History

Last 12 Months

Days to cover for Illumina (ILMN) currently stands at 2.9 days, up 80.4% from the previous period. The ratio is the reported short interest divided by the average daily trading volume. Across the settlements charted above, it has ranged from 1.6 to 5.6 days.

ILMN Company Profile & Sector Positioning

Illumina (ILMN) operates in the Diagnostics & Research industry within the broader Healthcare sector and is listed on the NASDAQ.

Investors comparing ILMN often look at related companies in the same sector, including IQVIA Holdings Inc. (IQV), Waters Corp (WAT), Mettler-Toledo International (MTD), Quest Diagnostics Inc. (DGX), and Agilent Technologies Inc. (A). Comparing financial metrics, valuation ratios, and stock performance across these peers can help investors evaluate ILMN's relative position within its industry.

Frequently Asked Questions

The current stock price of Illumina (ILMN) is $213.10 as of November 6, 2026.

The market cap of Illumina (ILMN) is approximately $32.2B. Learn more about what market capitalization means .

The FY2025 revenue of Illumina (ILMN) is $4.3B, from its most recent completed fiscal year.

The FY2025 net income of Illumina (ILMN) is $850.0M, from its most recent completed fiscal year.

The diluted earnings per share (EPS) of Illumina (ILMN) is $5.45 for FY2025, its most recent completed fiscal year. Learn more about EPS .

The operating cash flow of Illumina (ILMN) is $1.1B for FY2025, its most recent completed fiscal year. Learn about cash flow.

The net profit margin of Illumina (ILMN) is 19.6% for FY2025, its most recent completed fiscal year. Learn about profit margins.

The operating profit margin of Illumina (ILMN) is 18.6% for FY2025, its most recent completed fiscal year. Learn about operating margins.

The gross profit margin of Illumina (ILMN) is 66.1% for FY2025, its most recent completed fiscal year. Learn about gross margins.

The current ratio of Illumina (ILMN), current assets divided by current liabilities, was 2.08 at the end of FY2025, its most recent completed fiscal year. Learn about liquidity ratios.

The gross profit of Illumina (ILMN) is $2.9B for FY2025, its most recent completed fiscal year.

The operating income of Illumina (ILMN) is $807.0M for FY2025, its most recent completed fiscal year. Learn about operating income.

Illumina Inc develops and manufactures DNA sequencing and array-based technologies, along with related tools and services to analyze genetic material. According to company statements, its products are used in research, clinical, and applied markets for applications in life sciences, oncology, reproductive health, agriculture, and other emerging segments.

Illumina generates the majority of its revenue from sequencing instruments, consumables, and services, with a smaller portion from microarrays. This reflects a business model built around genomic instruments and the ongoing use of consumables and associated services for genetic analysis.

Illumina operates in the analytical laboratory instrument manufacturing industry within the broader manufacturing sector. Its activities focus on DNA sequencing, array-based technologies, and related genomic and multiomic tools and software.

Illumina states that it serves customers in the research, clinical, and applied markets. Its technologies are used in the life sciences, oncology, reproductive health, agriculture, and other emerging segments, as described in multiple company press releases.

Illumina describes itself as building comprehensive multiomic solutions anchored on its sequencing platforms. It has launched Illumina Connected Multiomics, a cloud-based software platform for integrating and analyzing multiomic data, and it uses AI-enabled tools such as PrimateAI and PromoterAI for variant interpretation. The company’s BioInsight business and the Illumina Billion Cell Atlas are positioned as data products to support AI-driven drug discovery.

The Illumina Billion Cell Atlas, described in a company press release, is a large genome-wide genetic perturbation dataset being built to accelerate drug discovery through AI. It captures how individual cells respond to genetic changes via CRISPR across many disease-relevant cell lines, with the goal of validating genetic targets, training AI models, and advancing research into disease mechanisms.

Illumina Connected Multiomics is a cloud-based research software platform announced by the company to analyze and visualize multiomic and multimodal biological data at scale. According to Illumina, it integrates data across transcriptomics, genomics, proteomics, epigenetics, and more, using DRAGEN secondary analysis and AI-enabled variant interpretation to help researchers focus on biological insights.

Illumina has introduced Illumina Protein Prep, which it describes as delivering broad coverage of the blood proteome and enabling integration of proteomics into large-scale genomics studies. In addition, an 8-K filing details a Stock Purchase Agreement under which Illumina will acquire Standard BioTools’ aptamer-based and functional proteomics business, including SomaLogic, subject to regulatory approvals and customary closing conditions.

Illumina has announced an alliance framework with AstraZeneca, Merck, and Eli Lilly and Company as founding participants in the Illumina Billion Cell Atlas program, aimed at accelerating drug discovery and target validation. The company has also disclosed a collaboration and strategic investment with MyOme to support a large-scale trial using whole-genome sequencing combined with AI-integrated risk models for common, chronic conditions, cancers, and rare diseases.

According to multiple Form 8-K filings, Illumina’s common stock is registered under Section 12(b) of the Exchange Act and trades on The Nasdaq Stock Market LLC under the ticker symbol ILMN.