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MARKET LEADERS
52-WEEK LEADER
WOLF +1854%
Wolfspeed, Inc.
2021 YTD LEADER
GEN +5243%
Gen Digital Inc.
APR 2021 LEADER
CUE +2859%
Cue Biopharma, Inc.
📈 52-Week Top 5 Full List →
1 WOLF +1853.6% 2 BW +851.0% 3 BE +760.2% 4 EVC +354.9% 5 CIEN +340.6%
📅 2021 YTD Top 5 Full List →
1 GEN +5242.7% 2 ENLT +4533.2% 3 CLS +3709.6% 4 STRL +3471.4% 5 AEHR +3249.2%
🗓 April 2021 Top 5 Full List →
1 CUE +2858.5% 2 BTX +1228.0% 3 IMUX +811.6% 4 ELP +385.7% 5 PLBY +112.8%
Quick Access: 52-Week 2021 YTD Apr 2021 Market Cap Dividends
#1 CUE leads with +2,859% April 2021

CUE (Cue Biopharma, Inc.) is the best performing stock in April 2021. Following are BTX (+1,228%) and IMUX (+812%). Top performing sectors: Financial Services (+202% avg, 1 in top 10), Healthcare (+158% avg, 6 in top 10), Utilities (+144% avg, 1 in top 10).

Top Stock Gainers April 2021 - Monthly Performance Ranked

Track the top performing stocks of April 2021 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.

Best performing large-cap stocks in April 2021

BNTX BioNTech SE +65.35% $23.13B
MRNA Moderna, Inc. +34.91% $24.53B
EFX Equifax Inc. +25.53% $21.36B
UPS United Parcel Service, Inc. +19.02% $100.06B
IQV IQVIA Holdings Inc. +18.49% $34.42B
2021
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

This ranking shows the top performing stocks and biggest stock gainers during April 2021, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

April 2021 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in April 2021. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

Data as of July 18, 2026 at 8:10 AM EDT

Rank
Symbol
Company Name
Apr Gain
Market Cap
Price
Country
Sector
1
CUE
Cue Biopharma, Inc.
2858.54%
130.88 M
$ 31.16
United States
Healthcare
2
BTX
BlackRock Innovation and Gr...
1228%
934.85 M
$ 8.01
United States
Financial Services
3
IMUX
Immunic, Inc.
811.57%
206.50 M
$ 15.16
United States
Healthcare
4
ELP
Companhia Paranaense de Ene...
385.71%
6.53 B
$ 9.31
Brazil
Utilities
5
PLBY
Playboy, Inc.
112.83%
135.25 M
$ 1.17
United States
Consumer Cyclical
6
GALT
Galectin Therapeutics Inc.
100.91%
274.95 M
$ 4.175
United States
Healthcare
7
OCGN
Ocugen, Inc.
89.1%
460.39 M
$ 1.36
United States
Healthcare
8
CELC
Celcuity Inc.
87.53%
4.31 B
$ 88.38
United States
Healthcare
9
BBQ
BBQ Holdings, Inc.
66.46%
185.50 M
$ 17.24
10
BNTX
BioNTech SE
65.35%
23.13 B
$ 91.48
Germany
Healthcare
11
NFGC
New Found Gold Corp.
62.43%
530.03 M
$ 1.38
Canada
Basic Materials
12
BRBS
Blue Ridge Bankshares, Inc.
61.39%
311.09 M
$ 3.46
United States
Financial Services
13
CYBN
Cybin Inc.
59.29%
148.61 M
$ 6.01
Canada
Healthcare
14
MRLN
Merlin, Inc.
58.02%
346.52 M
$ 3.59
United States
Industrials
15
NVCR
NovoCure Limited
53.06%
1.84 B
$ 15.92
Switzerland
Healthcare
16
UXIN
Uxin Limited
52.79%
370.67 M
$ 1.685
China
Consumer Cyclical
17
GNK
Genco Shipping & Trading Li...
49.95%
1.05 B
$ 24.12
United States
Industrials
18
LND
BrasilAgro - Companhia Bras...
46.6%
371.57 M
$ 3.73
Brazil
Consumer Defensive
19
SB
Safe Bulkers, Inc.
46.53%
694.46 M
$ 6.82
Monaco
Industrials
20
LNW
Light & Wonder, Inc.
45.97%
7.42 B
$ 88.43
United States
Consumer Cyclical
21
ESEA
Euroseas Ltd.
44.43%
488.44 M
$ 69.23
Greece
Industrials
22
ATNF
ETHZilla Corporation
44.03%
1.08 B
$ 7.04
United States
Healthcare
23
NMM
Navios Maritime Partners L.P.
42.73%
2.03 B
$ 71.37
Greece
Industrials
24
BSET
Bassett Furniture Industrie...
41.85%
187.02 M
$ 21.6
United States
Consumer Cyclical
25
ZIM
ZIM Integrated Shipping Ser...
41.43%
2.93 B
$ 24.3
Israel
Industrials
26
HPK
HighPeak Energy, Inc.
40.15%
930.63 M
$ 7.365
United States
Energy
27
SID
Companhia Siderúrgica Nacional
40.06%
1.32 B
$ 0.9911
Brazil
Basic Materials
28
ZNTL
Zentalis Pharmaceuticals, Inc.
36.87%
363.76 M
$ 5.11
United States
Healthcare
29
MNMD
Mind Medicine (MindMed) Inc.
36.71%
1.46 B
$ 15.02
United States
Healthcare
30
TV
Grupo Televisa, S.A.B.
36.49%
1.43 B
$ 2.71
Mexico
Communication Services
31
BAK
Braskem S.A.
36.34%
980.27 M
$ 2.46
Brazil
Basic Materials
32
GENI
Genius Sports Limited
35%
1.68 B
$ 6.3
United Kingdom
Communication Services
33
MRNA
Moderna, Inc.
34.91%
24.53 B
$ 61.82
United States
Healthcare
34
CCO
Clear Channel Outdoor Holdi...
33.51%
1.23 B
$ 2.42
United States
Communication Services
35
CLOV
Clover Health Investments, ...
33.47%
2.43 B
$ 4.62
United States
Healthcare
36
CLDX
Celldex Therapeutics, Inc.
32.97%
2.77 B
$ 35.35
United States
Healthcare
37
CRCT
Cricut, Inc.
32.5%
971.83 M
$ 4.63
United States
Technology
38
GDEN
Golden Entertainment Inc
30.37%
753.69 M
$ 28.55
United States
Consumer Cyclical
39
FLNG
FLEX LNG Ltd.
30.17%
1.66 B
$ 30.67
Bermuda
Energy
40
STGW
Stagwell Inc.
29.65%
1.86 B
$ 7.51
United States
Communication Services
41
STAA
STAAR Surgical Company
29.55%
1.32 B
$ 26.44
United States
Healthcare
42
BUR
Burford Capital Limited
28.96%
858.75 M
$ 3.92
Guernsey
Financial Services
43
KTB
Kontoor Brands, Inc.
28.91%
4.73 B
$ 85.57
United States
Consumer Cyclical
44
SEMR
SEMrush Holdings Inc
28.72%
1.81 B
$ 12
United States
Technology
45
SBLK
Star Bulk Carriers Corp.
28.57%
2.78 B
$ 24.9
Greece
Industrials
46
TH
Target Hospitality Corp.
28.57%
1.63 B
$ 16.36
United States
Industrials
47
EXTR
Extreme Networks, Inc.
28.44%
3.97 B
$ 30.34
United States
Technology
48
CVAC
CureVac N.V.
28.24%
1.21 B
$ 5.39
Germany
Healthcare
49
AORT
Artivion, Inc.
28.21%
1.22 B
$ 25.06
United States
Healthcare
50
NEGG
Newegg Commerce, Inc.
27.79%
272.44 M
$ 12.99
United States
Consumer Cyclical
51
TSHA
Taysha Gene Therapies, Inc.
27.77%
1.71 B
$ 5.96
United States
Healthcare
52
NVAX
Novavax, Inc.
27.51%
1.35 B
$ 8.21
United States
Healthcare
53
STTK
Shattuck Labs, Inc.
27.34%
719.18 M
$ 7.53
United States
Healthcare
54
TDC
Teradata Corporation
27.07%
2.87 B
$ 30.52
United States
Technology
55
ZLAB
Zai Lab Limited
26.92%
2.28 B
$ 20.2
China
Healthcare
56
VHI
Valhi, Inc.
26.89%
393.12 M
$ 13.89
United States
Basic Materials
57
GNW
Genworth Financial, Inc.
26.69%
3.86 B
$ 10.09
United States
Financial Services
58
CHRD
Chord Energy Corporation
26.33%
7.21 B
$ 128.1
United States
Energy
59
CROX
Crocs, Inc.
25.84%
6.81 B
$ 137.13
United States
Consumer Cyclical
60
LOVE
The Lovesac Company
25.72%
266.49 M
$ 18.205
United States
Consumer Cyclical
61
EFX
Equifax Inc.
25.53%
21.36 B
$ 177.08
United States
Industrials
62
TBI
TrueBlue, Inc.
25.44%
258.13 M
$ 8.49
United States
Industrials
63
OPY
Oppenheimer Holdings Inc.
25.29%
1.17 B
$ 109.13
United States
Financial Services
64
RILY
BRC Group Holdings, Inc.
25.27%
274.53 M
$ 6.83
United States
Financial Services
65
BXC
BlueLinx Holdings Inc.
24.86%
470.52 M
$ 60.46
United States
Industrials
66
PGNY
Progyny, Inc.
24.67%
2.50 B
$ 31.93
United States
Healthcare
67
OUST
Ouster, Inc.
24.57%
2.49 B
$ 37.04
United States
Technology
68
VTLE
Vital Energy, Inc.
24.55%
648.56 M
$ 16.76
United States
Energy
69
PAR
PAR Technology Corporation
24.47%
674.38 M
$ 16.35
United States
Technology
70
UAN
CVR Partners, LP
24.47%
1.26 B
$ 119.02
United States
Basic Materials
71
CTRN
Citi Trends, Inc.
24.33%
534.86 M
$ 64.21
United States
Consumer Cyclical
72
HDSN
Hudson Technologies, Inc.
24.1%
259.56 M
$ 6.17
United States
Basic Materials
73
UTL
Unitil Corporation
23.99%
981.40 M
$ 54.55
United States
Utilities
74
INGN
Inogen, Inc.
23.87%
177.88 M
$ 6.57
United States
Healthcare
75
JAKK
JAKKS Pacific, Inc.
23.72%
277.30 M
$ 24.23
United States
Consumer Cyclical
76
KRRO
Korro Bio, Inc.
23.64%
176.68 M
$ 12.25
United States
Healthcare
77
DYN
Dyne Therapeutics, Inc.
23.46%
3.92 B
$ 23.74
United States
Healthcare
78
DCBO
Docebo Inc.
23.1%
517.30 M
$ 20.38
Canada
Technology
79
BTU
Peabody Energy Corporation
22.92%
2.73 B
$ 22.44
United States
Energy
80
IMAB
I-Mab
22.91%
318.48 M
$ 3.9
United States
Healthcare
81
TMCI
Treace Medical Concepts, Inc.
22.84%†
278.95 M
$ 4.3
United States
Healthcare
82
MAX
MediaAlpha, Inc.
22.78%
763.36 M
$ 14.12
United States
Communication Services
83
DBVT
DBV Technologies S.A.
22.74%
870.04 M
$ 14.7
France
Healthcare
84
ACH
Accendra Health, Inc.
22.64%
265.75 M
$ 3.47
United States
Healthcare
85
HVT
Haverty Furniture Companies...
22.61%
412.52 M
$ 25.63
United States
Consumer Cyclical
86
ONEW
OneWater Marine Inc.
22.56%
223.84 M
$ 13.47
United States
Consumer Cyclical
87
NEWP
New Pacific Metals Corp.
21.9%
755.08 M
$ 4.08
Canada
Basic Materials
88
DSX
Diana Shipping Inc.
21.83%
255.03 M
$ 2.05
Greece
Industrials
89
LEVI
Levi Strauss & Co.
21.82%
9.37 B
$ 24.36
United States
Consumer Cyclical
90
PANL
Pangaea Logistics Solutions...
21.77%
459.87 M
$ 7.03
United States
Industrials
91
JYNT
The Joint Corp.
21.72%
127.02 M
$ 8.91
United States
Healthcare
92
BWMX
Betterware de México, S.A.P...
21.7%
683.05 M
$ 18.34
Mexico
Consumer Cyclical
93
TIGR
UP Fintech Holding Limited
21.5%
823.81 M
$ 4.61
Singapore
Financial Services
94
SNCY
Sun Country Airlines Holdin...
21.49%
876.36 M
$ 16.17
United States
Industrials
95
FLXS
Flexsteel Industries, Inc.
21.25%
297.44 M
$ 72.98
United States
Consumer Cyclical
96
CRI
Carter's, Inc.
21.11%
1.40 B
$ 38.1
United States
Consumer Cyclical
97
CDZI
Cadiz Inc.
21.1%
285.89 M
$ 3.4
United States
Utilities
98
HOG
Harley-Davidson, Inc.
21.05%
2.80 B
$ 26.58
United States
Consumer Cyclical
99
SIM
Grupo Simec, S.A.B. de C.V.
20.83%
4.58 B
$ 29.84
Mexico
Basic Materials
100
CAR
Avis Budget Group, Inc.
20.75%
5.67 B
$ 160.57
United States
Industrials
† Return measured from the start of the stock's current trading history (a recent listing or relisting), not from the start of the month.
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in April 2021?
A

CUE (Cue Biopharma, Inc.) has the highest monthly gain in this ranking for April 2021, with a gain of 2,859%. Top performers this month include CUE, BTX, IMUX.

Q What stocks gained the most in April 2021?
A

The biggest gainers in April 2021 were: CUE (+2,859%), BTX (+1,228%), IMUX (+812%), ELP (+386%), PLBY (+113%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during April 2021. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during April 2021. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in April 2021?
A

The top performing sectors in April 2021 included Healthcare, Financial Services, Utilities, based on the stocks with highest monthly gains. CUE led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in April 2021. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.