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#1 SLNO leads with +493% September 2023

Among the 3,452 NYSE, Nasdaq and NYSE American stocks currently eligible for this ranking, SLNO (Soleno Therapeutics, Inc.) has the highest gain in September 2023 with +493%. Following are THTX (+128%) and GPCR (+72%). Top performing sectors: Healthcare (+42% avg, 9 in top 10), Real Estate (+31% avg), Financial Services (+28% avg, 1 in top 10).

Top Stock Gainers September 2023 - Monthly Performance Ranked

Track the top performing stocks of September 2023 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.

Best performing large-cap stocks in September 2023

SMMT Summit Therapeutics Inc. +14.72% $10.01B
CNC Centene Corporation +12.42% $31.56B
CASY Casey's General Stores, Inc. +11.63% $31.71B
INSM Insmed Incorporated +11.53% $22.57B
JBL Jabil Inc. +9.94% $31.75B
2023

This ranking shows the top performing stocks and biggest stock gainers during September 2023, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

September 2023 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in September 2023. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

September 2023 ranking, complete through September 29, 2023

21 stocks are withheld from this ranking because their price history is under review.

The gain covers the period above. Price, market cap, sector and country show each company as it is today, not as it was then.

Rank
Symbol
Company Name
Sep Gain
Market Cap (today)
Price (today)
Country
Sector
1
492.57%
2.76 B
$ 53.01
United States
Healthcare
2
128.12%
150.81 M
$ 3.28
Canada
Healthcare
3
71.67%
3.40 B
$ 47.89
United States
Healthcare
4
70.87%
148.61 M
$ 6.01
Canada
Healthcare
5
70.53%
8.88 B
$ 83.86
United States
Healthcare
6
60.03%
7.99 B
$ 38.9
United States
Healthcare
7
57.26%
4.34 B
$ 26.65
United States
Healthcare
8
52.46%
272.90 M
$ 5.09
United States
Healthcare
9
49.34%
600.84 M
$ 8.44
United States
Healthcare
10
48.08%
199.80 M
$ 9.99
France
Financial Services
11
47.5%
171.10 M
$ 0.4084
United States
Communication Services
12
47.06%
185.71 M
$ 3.84
United States
Healthcare
13
45.5%
324.38 M
$ 11.53
United States
Industrials
14
42.33%
400.97 M
$ 0.8942
Canada
Healthcare
15
39.3%
231.14 M
$ 3.86
United States
Healthcare
16
37.33%
2.07 B
$ 13.77
United States
Healthcare
17
36.03%
181.01 M
$ 2.06
Canada
Healthcare
18
36.02%
636.78 M
$ 9.75
United States
Basic Materials
19
35.22%
363.83 M
$ 4.39
United States
Industrials
20
32.06%
1.03 B
$ 19.52
United States
Healthcare
21
30.9%
209.50 M
$ 17.58
United States
Real Estate
22
30.61%
150.26 M
$ 5.17
United States
Healthcare
23
30.16%
1.07 B
$ 28.1
United States
Communication Services
24
30.07%
187.90 M
$ 14.62
Israel
Healthcare
25
29.86%
173.74 M
$ 6.31
United States
Healthcare
26
29.34%
100.81 M
$ 3.07
United States
Healthcare
27
28.63%
352.44 M
$ 10.2
United Kingdom
Energy
28
28.41%
688.58 M
$ 14.61
United States
Utilities
29
28.06%
342.87 M
$ 3.14
United States
Healthcare
30
27.68%
2.63 B
$ 23.22
United States
Healthcare
31
26.65%
1.13 B
$ 5.89
Singapore
Healthcare
32
26.42%
111.82 M
$ 1.94
United States
Industrials
33
26.23%
1.61 B
$ 23.6
United States
Consumer Cyclical
34
25.05%
114.24 M
$ 2.65
Canada
Healthcare
35
24.84%
1.25 B
$ 1.46
China
Healthcare
36
24.46%
803.58 M
$ 22.19
United States
Basic Materials
37
24.42%
6.33 B
$ 9.72
United States
Technology
38
23.97%
168.48 M
$ 2.72
Canada
Healthcare
39
23.92%
4.17 B
$ 79
United States
Basic Materials
40
23.43%
1.55 B
$ 36.81
United States
Consumer Cyclical
41
22.79%
183.99 M
$ 1.72
United States
Basic Materials
42
22.45%
904.88 M
$ 29.89
United States
Financial Services
43
22.22%
345.83 M
$ 3.08
Singapore
Technology
44
22.2%
157.09 M
$ 1.94
United States
Healthcare
45
21.95%
1.73 B
$ 28.69
Denmark
Healthcare
46
21.81%
1.95 B
$ 17
United States
Consumer Cyclical
47
21.8%
1.84 B
$ 145.07
United States
Basic Materials
48
21.74%
494.92 M
$ 4.95
United States
Healthcare
49
20.7%
3.81 B
$ 18.43
United States
Healthcare
50
20.18%
433.39 M
$ 1.79
United States
Technology
51
20.11%
344.81 M
$ 4.45
United States
Basic Materials
52
20%
3.57 B
$ 51.605
United Arab Emirates
Communication Services
53
19.52%
6.84 B
$ 112.23
United States
Healthcare
54
19.27%
1.64 B
$ 64.87
United States
Healthcare
55
19.24%
214.19 M
$ 1.67
United Kingdom
Consumer Defensive
56
18.9%
872.74 M
$ 5.21
United States
Healthcare
57
18.44%
292.29 M
$ 180.65
United States
Energy
58
17.1%
101.69 M
$ 11.24
United States
Healthcare
59
17.02%
2.49 B
$ 2.75
Canada
Energy
60
16.58%
177.53 M
$ 4.13
United States
Energy
61
16.4%
1.01 B
$ 11.62
United States
Healthcare
62
16.34%
168.76 M
$ 1.52
United States
Healthcare
63
16.24%
960.38 M
$ 27.15
United States
Communication Services
64
16.03%
3.12 B
$ 63.9
United States
Industrials
65
15.98%
153.24 M
$ 2.9
United Kingdom
Technology
66
15.85%
345.26 M
$ 14.53
United States
Energy
67
15.77%
1.84 B
$ 13.45
United States
Technology
68
15.66%
389.71 M
$ 2.23
United States
Utilities
69
15.62%
3.34 B
$ 169.65
United States
Energy
70
15.53%
545.56 M
$ 11.55
United Kingdom
Healthcare
71
15.26%
2.58 B
$ 25.55
United States
Energy
72
14.81%
133.21 M
$ 1.07
Canada
Healthcare
73
14.77%
621.63 M
$ 15.49
Israel
Healthcare
74
14.75%
1.10 B
$ 4.64
France
Healthcare
75
14.72%
299.54 M
$ 80
United States
Technology
76
14.72%
10.01 B
$ 12.55
United States
Healthcare
77
14.68%
277.95 M
$ 18.59
United States
Consumer Cyclical
78
14.6%
137.58 M
$ 13.76
United States
Healthcare
79
14.44%
421.59 M
$ 3.28
Brazil
Technology
80
14.32%
3.94 B
$ 67.48
United States
Industrials
81
14.26%
445.14 M
$ 2.73
United States
Healthcare
82
13.89%
407.53 M
$ 2.78
Canada
Energy
83
13.86%
102.03 M
$ 6.81
United States
Healthcare
84
13.75%
7.91 B
$ 156.35
United States
Industrials
85
13.72%
853.35 M
$ 2.45
United States
Industrials
86
13.65%
7.16 B
$ 64.29
Mexico
Energy
87
13.64%
512.50 M
$ 10.17
United States
Industrials
88
13.54%
2.83 B
$ 11.33
United States
Energy
89
13.4%
2.13 B
$ 8.43
Israel
Consumer Cyclical
90
13.39%
239.56 M
$ 3.34
United States
Healthcare
91
13.36%
747.37 M
$ 34.36
United States
Industrials
92
13.34%
322.43 M
$ 6.35
United States
Consumer Cyclical
93
13.28%
6.08 B
$ 9.18
Canada
Energy
94
13.27%
3.67 B
$ 134.87
United States
Consumer Cyclical
95
13.16%
3.33 B
$ 25.91
United States
Energy
96
13.03%
376.23 M
$ 34.38
United States
Consumer Cyclical
97
12.88%
5.92 B
$ 49.37
United States
Healthcare
98
12.83%
263.45 M
$ 7.25
Canada
Healthcare
99
12.69%
2.54 B
$ 62.77
United States
Financial Services
100
12.67%
1.31 B
$ 52.61
United States
Technology
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in September 2023?
A

SLNO (Soleno Therapeutics, Inc.) has the highest monthly gain in this ranking for September 2023, with a gain of 493%. Top performers this month include SLNO, THTX, GPCR.

Q What stocks gained the most in September 2023?
A

The biggest gainers in September 2023 were: SLNO (+493%), THTX (+128%), GPCR (+72%), CYBN (+71%), CRNX (+71%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during September 2023. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during September 2023. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in September 2023?
A

The top performing sectors in September 2023 included Healthcare, based on the stocks with highest monthly gains. SLNO led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in September 2023. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.