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MARKET LEADERS
52-WEEK LEADER
WOLF +2701%
Wolfspeed, Inc.
2025 YTD LEADER
RGC +5018%
Regencell Bioscience H..
JUL 2025 LEADER
ABVX +837%
ABIVAX Société Anonyme
📈 52-Week Top 5 Full List →
1 WOLF +2700.8% 2 BW +991.4% 3 BE +911.9% 4 CIEN +494.6% 5 TE +426.1%
📅 2025 YTD Top 5 Full List →
1 RGC +5018.3% 2 SNDK +3453.9% 3 AXTI +2645.2% 4 MGRT +1963.5% 5 TOI +1825.7%
🗓 July 2025 Top 5 Full List →
1 ABVX +837.0% 2 PROK +390.1% 3 NEGG +306.3% 4 ATNF +268.5% 5 LIXT +236.4%
Quick Access: 52-Week 2025 YTD Jul 2025 Market Cap Dividends
#1 RGC leads with +5,018% 2025 YTD

RGC (Regencell Bioscience Holdings Limited) is the best performing stock in 2025 year-to-date. Following are SNDK (+3,454%) and AXTI (+2,645%). Top performing sectors: Technology (+694% avg, 3 in top 10), Healthcare (+673% avg, 7 in top 10), Industrials (+530% avg).

Top Performing Stocks 2025 - Year-to-Date Gainers Ranked

Discover the best US stocks of 2025 ranked by year-to-date performance. This ranking tracks YTD gains and highest YTD returns from January 1st, 2025 to today, featuring the top stock gainers with market caps over $100 million on Nasdaq and NYSE.

This ranking shows the top performing US stocks and biggest stock gainers of 2025, calculated from January 1st to the most recent trading day. See which stocks delivered the highest YTD returns this year. Using split-adjusted data ensures accurate performance calculations that account for stock splits and corporate actions.

Year-to-date performance helps investors identify stocks that have been outperforming the market in the current year, revealing trends and momentum that may continue through the rest of 2025.

Looking for a specific Symbol?

Data as of July 9, 2026 at 9:35 PM EDT

Rank
Symbol
Company Name
YTD Gain
Market Cap
Price
Country
Sector
1
RGC
Regencell Bioscience Holdin...
5018.3%
3.21 B
$ 6.49
Hong Kong
Healthcare
2
SNDK
Sandisk Corporation
3453.87%†
255.78 B
$ 1727.18
United States
Technology
3
AXTI
AXT, Inc.
2645.21%
3.93 B
$ 60.12
United States
Technology
4
MGRT
Mega Fortune Company Limited
1963.52%†
1.08 B
$ 78.62
Hong Kong
Technology
5
TOI
The Oncology Institute, Inc.
1825.7%
564.90 M
$ 5.65
United States
Healthcare
6
ABVX
ABIVAX Société Anonyme
1800.41%
12.08 B
$ 138.54
France
Healthcare
7
RLMD
Relmada Therapeutics, Inc.
1324.13%
672.97 M
$ 6.41
United States
Healthcare
8
NBTX
Nanobiotix S.A.
1237.93%
1.97 B
$ 38.8
France
Healthcare
9
SLS
SELLAS Life Sciences Group,...
1185.98%
2.71 B
$ 13.76
United States
Healthcare
10
PVLA
Palvella Therapeutics, Inc.
1109.92%
2.08 B
$ 145.19
United States
Healthcare
11
ROMA
Roma Green Finance Limited
993.67%
491.71 M
$ 8.255
Hong Kong
Industrials
12
BE
Bloom Energy Corporation
988.1%
72.33 B
$ 254.29
United States
Industrials
13
MU
Micron Technology, Inc.
986.45%
1.07 T
$ 948.8
United States
Technology
14
STX
Seagate Technology Holdings...
895.51%
194.58 B
$ 860.02
Singapore
Technology
15
TNGX
Tango Therapeutics, Inc.
878.91%
4.99 B
$ 30.64
United States
Healthcare
16
NUAI
New Era Energy & Digital, Inc.
822.59%†
440.62 M
$ 4.35
United States
Technology
17
HYMC
Hycroft Mining Holding Corp...
811.84%
1.90 B
$ 20.79
United States
Basic Materials
18
WDC
Western Digital Corporation
789.45%
189.68 B
$ 550.3
United States
Technology
19
BVC
BitVentures Limited
741.25%†
1.70 B
$ 10.095
Hong Kong
Technology
20
CELC
Celcuity Inc.
729.4%
5.31 B
$ 108.9
United States
Healthcare
21
LITE
Lumentum Holdings Inc.
726.05%
55.01 B
$ 707.1
United States
Technology
22
VSAT
Viasat, Inc.
676.5%
10.11 B
$ 74
United States
Technology
23
SLGL
Sol-Gel Technologies Ltd.
636.55%
244.39 M
$ 74.76
Israel
Healthcare
24
PL
Planet Labs PBC
598.99%
9.89 B
$ 27.75
United States
Industrials
25
ERAS
Erasca, Inc.
598.89%
5.87 B
$ 18.87
United States
Healthcare
26
LQDA
Liquidia Corporation
556.78%
7.07 B
$ 79.47
United States
Healthcare
27
CLYM
Climb Bio, Inc.
555.56%
777.06 M
$ 13.57
United States
Healthcare
28
INBX
Inhibrx Biosciences, Inc.
536.72%
1.42 B
$ 97.1
United States
Healthcare
29
ACMR
ACM Research, Inc.
529.87%
6.78 B
$ 98.07
United States
Technology
30
BW
Babcock & Wilcox Enterprise...
522.54%
1.60 B
$ 10.77
United States
Industrials
31
APPS
Digital Turbine, Inc.
496.59%
1.27 B
$ 10.5
United States
Technology
32
ASM
Avino Silver & Gold Mines Ltd.
492.31%
1.00 B
$ 5.73
Canada
Basic Materials
33
TTMI
TTM Technologies, Inc.
491.09%
15.09 B
$ 145.29
United States
Technology
34
SIF
SIFCO Industries, Inc.
480.05%
132.78 M
$ 21.23
United States
Industrials
35
SIMO
Silicon Motion Technology C...
473.28%
10.62 B
$ 313.3
Hong Kong
Technology
36
STTK
Shattuck Labs, Inc.
468.6%
657.10 M
$ 6.88
United States
Healthcare
37
GORO
Gold Resource Corporation
467.57%
205.88 M
$ 1.26
United States
Basic Materials
38
LASR
nLIGHT, Inc.
464.23%
3.31 B
$ 58.68
United States
Technology
39
VICR
Vicor Corporation
445.75%
12.00 B
$ 263.16
United States
Technology
40
INTC
Intel Corporation
445.2%
554.07 B
$ 110.24
United States
Technology
41
ATRO
Astronics Corporation
440.88%
3.51 B
$ 71.17
United States
Industrials
42
WOLF
Wolfspeed, Inc.
440.87%
1.86 B
$ 35.86
United States
Technology
43
TE
T1 Energy Inc.
440.44%†
2.05 B
$ 7.35
United States
Industrials
44
PHOE
Phoenix Asia Holdings Limited
440.27%†
425.95 M
$ 19.72
Hong Kong
Industrials
45
BUUU
BUUU Group Limited
432%†
355.27 M
$ 21.28
Hong Kong
Industrials
46
CIEN
Ciena Corporation
429.76%
62.42 B
$ 440.97
United States
Technology
47
NUTX
Nutex Health Inc.
417.14%
1.24 B
$ 179.55
United States
Healthcare
48
DBVT
DBV Technologies S.A.
415.38%
991.38 M
$ 16.75
France
Healthcare
49
PGEN
Precigen, Inc.
414.81%
1.98 B
$ 5.56
United States
Healthcare
50
COGT
Cogent Biosciences, Inc.
412.44%
6.83 B
$ 39.97
United States
Healthcare
51
EVC
Entravision Communications ...
404.74%
1.08 B
$ 11.71
United States
Communication Services
52
IMMX
Immix Biopharma, Inc.
400%
783.09 M
$ 11
United States
Healthcare
53
NKTR
Nektar Therapeutics
398.79%
2.43 B
$ 71.9
United States
Healthcare
54
DWSN
Dawson Geophysical Company
394.16%
210.23 M
$ 6.77
United States
Energy
55
SIFY
Sify Technologies Limited
394.12%
1.10 B
$ 15.12
India
Communication Services
56
GH
Guardant Health, Inc.
391.56%
20.71 B
$ 156.17
United States
Healthcare
57
ANAB
AnaptysBio, Inc.
389.15%
1.93 B
$ 65.35
United States
Healthcare
58
HUT
Hut 8 Corp.
384.74%
11.95 B
$ 106.11
United States
Financial Services
59
ENLT
Enlight Renewable Energy Ltd
382.11%
11.68 B
$ 83.55
Israel
Utilities
60
KOD
Kodiak Sciences Inc.
371.35%
2.54 B
$ 40.63
United States
Healthcare
61
CYD
China Yuchai International ...
367.06%
1.77 B
$ 47.08
Singapore
Consumer Cyclical
62
TDUP
ThredUp Inc.
364.54%
845.22 M
$ 6.55
United States
Consumer Cyclical
63
AGX
Argan, Inc.
364.32%
9.33 B
$ 665.46
United States
Industrials
64
VPG
Vishay Precision Group, Inc.
364.3%
1.44 B
$ 107.95
United States
Technology
65
LRCX
Lam Research Corporation
359.9%
416.63 B
$ 333.15
United States
Technology
66
AMLX
Amylyx Pharmaceuticals, Inc.
357.29%
1.99 B
$ 17.88
United States
Healthcare
67
RLAY
Relay Therapeutics, Inc.
356.51%
4.28 B
$ 19.63
United States
Healthcare
68
CIFR
Cipher Digital Inc.
352.38%
8.94 B
$ 21.85
United States
Technology
69
RFIL
RF Industries, Ltd.
348.16%
185.77 M
$ 17.12
United States
Industrials
70
MNPR
Monopar Therapeutics Inc.
346.76%
665.02 M
$ 99.27
United States
Healthcare
71
THM
International Tower Hill Mi...
345.86%
558.23 M
$ 2.1
Canada
Basic Materials
72
MXL
MaxLinear, Inc.
339.7%
7.71 B
$ 86.05
United States
Technology
73
ARWR
Arrowhead Pharmaceuticals, ...
336.34%
12.08 B
$ 85.74
United States
Healthcare
74
DAVE
Dave Inc.
335.07%
4.77 B
$ 375.51
United States
Technology
75
USAS
Americas Gold and Silver Co...
331.79%
1.42 B
$ 4.21
Canada
Basic Materials
76
RVMD
Revolution Medicines, Inc.
331.3%
40.34 B
$ 189.77
United States
Healthcare
77
AEVA
Aeva Technologies, Inc.
329.14%
1.45 B
$ 21.5
United States
Technology
78
AMD
Advanced Micro Devices, Inc.
328.92%
843.68 B
$ 517.405
United States
Technology
79
TRVI
Trevi Therapeutics, Inc.
326.38%
2.64 B
$ 18.59
United States
Healthcare
80
BIOA
BioAge Labs, Inc.
325%
1.05 B
$ 23.63
United States
Healthcare
81
DNTH
Dianthus Therapeutics, Inc.
322.72%
5.36 B
$ 98.07
United States
Healthcare
82
ORKA
Oruka Therapeutics, Inc.
322.63%
5.09 B
$ 84.4
United States
Healthcare
83
BAND
Bandwidth Inc.
321.84%
2.26 B
$ 70.49
United States
Technology
84
TSEM
Tower Semiconductor Ltd.
320.37%
25.78 B
$ 216.7
Israel
Technology
85
PRAX
Praxis Precision Medicines,...
318.75%
9.28 B
$ 332.99
United States
Healthcare
86
WULF
TeraWulf Inc.
318.13%
11.31 B
$ 22.83
United States
Financial Services
87
ANL
Adlai Nortye Ltd.
317.21%
655.57 M
$ 10.18
United States
Healthcare
88
DRTS
Alpha Tau Medical Ltd.
312.26%
1.15 B
$ 12.78
Israel
Healthcare
89
IREN
IREN Limited
311.14%
15.37 B
$ 43.005
Australia
Financial Services
90
PARR
Par Pacific Holdings, Inc.
310.84%
3.44 B
$ 68.57
United States
Energy
91
AEHR
Aehr Test Systems, Inc.
310.21%
2.14 B
$ 67.89
United States
Technology
92
DOCN
DigitalOcean Holdings, Inc.
310.01%
14.66 B
$ 140.47
United States
Technology
93
EQ
Equillium, Inc.
309.73%
199.16 M
$ 3.15
United States
Healthcare
94
PRLD
Prelude Therapeutics Incorp...
309.6%
407.78 M
$ 5.12
United States
Healthcare
95
ABSI
Absci Corporation
309.59%
1.88 B
$ 11.1
United States
Healthcare
96
VELO
Velo3D, Inc.
309.23%†
409.76 M
$ 13.75
United States
Technology
97
QTTB
Q32 Bio Inc.
308.12%
238.75 M
$ 14.08
United States
Healthcare
98
BTSG
BrightSpring Health Service...
306.81%
13.84 B
$ 70.5
United States
Healthcare
99
PENG
Penguin Solutions, Inc.
306.16%
4.02 B
$ 78.47
United States
Technology
100
AMPX
Amprius Technologies, Inc.
304.9%
1.64 B
$ 11.58
United States
Industrials
† Return measured from the start of the stock's current trading history (a recent listing or relisting), not from January 1st.
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q What is the best stock of 2025?
A

RGC (Regencell Bioscience Holdings Limited) is the best performing stock of 2025 with a year-to-date gain of 5,018% from January 1st to today. The top 3 stocks of 2025 are RGC, SNDK, AXTI.

Q What are the top performing stocks in 2025?
A

The top performing stocks in 2025 YTD are: RGC (+5,018%), SNDK (+3,454%), AXTI (+2,645%), MGRT (+1,964%), TOI (+1,826%). Performance is calculated from January 1, 2025 to the most recent trading day.

Q Which stocks have made the most money in 2025?
A

The biggest stock gainers of 2025 include RGC leading with +5,018%, followed by SNDK (+3,454%) and AXTI (+2,645%). These represent the best investment returns YTD.

Q What sectors are performing best in 2025?
A

In 2025, the best performing sectors based on top stock gains include Healthcare, Technology. The top gainer RGC operates in the Healthcare sector.

Q Which US stocks have the highest YTD returns in 2025?
A

The US stocks with the highest year-to-date returns in 2025 include RGC (+5,018%), SNDK (+3,454%), AXTI (+2,645%). These top YTD gainers are ranked by total return from January 1st to today across NYSE and NASDAQ.

Understanding Year-to-Date Stock Performance

Year-to-date (YTD) performance measures how much a stock's price has changed since January 1st of the current year. This metric is valuable for several reasons:

  • Current Trend Identification: YTD performance reveals which stocks are leading or lagging in the current market cycle, helping identify emerging trends before they become widely recognized.
  • Benchmark Comparison: Compare individual stock performance against market indices like the S&P 500 to assess whether investments are outperforming or underperforming the broader market.
  • Tax Planning: YTD gains and losses are crucial for tax-loss harvesting strategies and estimating potential capital gains tax obligations before year-end.

Factors Driving YTD Performance

Several factors can influence a stock's year-to-date performance:

  • Earnings Reports: Quarterly earnings that beat or miss expectations can significantly impact stock prices throughout the year.
  • Industry Trends: Sector rotation and changing market preferences can drive entire industries higher or lower.
  • Macroeconomic Factors: Interest rates, inflation data, and economic indicators affect stock valuations across the market.
  • Company-Specific News: Product launches, management changes, M&A activity, and regulatory developments can move individual stocks.

Model Your Returns

See exactly how much a YTD top performer would have returned on your investment with our Stock Return Calculator. Planning regular investments? The DCA Calculator shows how dollar-cost averaging into these stocks would have performed.