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MARKET LEADERS
52-WEEK LEADER
WOLF +1466%
Wolfspeed, Inc.
2025 YTD LEADER
RGC +4924%
Regencell Bioscience H..
JUL 2025 LEADER
ABVX +837%
ABIVAX Société Anonyme
📈 52-Week Top 5 Full List →
1 WOLF +1466.3% 2 BE +1114.2% 3 BW +967.9% 4 TE +476.7% 5 CIEN +451.5%
📅 2025 YTD Top 5 Full List →
1 RGC +4923.7% 2 SNDK +3490.5% 3 AXTI +2485.4% 4 MGRT +2049.1% 5 ABVX +1884.2%
🗓 July 2025 Top 5 Full List →
1 ABVX +837.0% 2 PROK +390.1% 3 NEGG +306.3% 4 ATNF +268.5% 5 LIXT +236.4%
Quick Access: 52-Week 2025 YTD Jul 2025 Market Cap Dividends
#1 RGC leads with +4,924% 2025 YTD

RGC (Regencell Bioscience Holdings Limited) is the best performing stock in 2025 year-to-date. Following are SNDK (+3,491%) and AXTI (+2,485%). Top performing sectors: Healthcare (+730% avg, 7 in top 10), Technology (+668% avg, 3 in top 10), Industrials (+527% avg).

Top Performing Stocks 2025 - Year-to-Date Gainers Ranked

Discover the best US stocks of 2025 ranked by year-to-date performance. This ranking tracks YTD gains and highest YTD returns from January 1st, 2025 to today, featuring the top stock gainers with market caps over $100 million on Nasdaq and NYSE.

This ranking shows the top performing US stocks and biggest stock gainers of 2025, calculated from January 1st to the most recent trading day. See which stocks delivered the highest YTD returns this year. Using split-adjusted data ensures accurate performance calculations that account for stock splits and corporate actions.

Year-to-date performance helps investors identify stocks that have been outperforming the market in the current year, revealing trends and momentum that may continue through the rest of 2025.

Looking for a specific Symbol?

Data as of July 7, 2026 at 12:14 AM EDT

Rank
Symbol
Company Name
YTD Gain
Market Cap
Price
Country
Sector
1
RGC
Regencell Bioscience Holdin...
4923.66%
3.15 B
$ 6.37
Hong Kong
Healthcare
2
SNDK
Sandisk Corporation
3490.53%†
258.42 B
$ 1745
United States
Technology
3
AXTI
AXT, Inc.
2485.39%
3.70 B
$ 56.62
United States
Technology
4
MGRT
Mega Fortune Company Limited
2049.08%†
1.13 B
$ 81.88
Hong Kong
Technology
5
ABVX
ABIVAX Société Anonyme
1884.22%
11.54 B
$ 144.65
France
Healthcare
6
TOI
The Oncology Institute, Inc.
1699.59%
527.91 M
$ 5.28
United States
Healthcare
7
SLS
SELLAS Life Sciences Group,...
1300%
2.95 B
$ 14.98
United States
Healthcare
8
RLMD
Relmada Therapeutics, Inc.
1295.25%
659.32 M
$ 6.28
United States
Healthcare
9
NBTX
Nanobiotix S.A.
1224.14%
1.95 B
$ 38.4
France
Healthcare
10
PVLA
Palvella Therapeutics, Inc.
1123%
2.10 B
$ 146.76
United States
Healthcare
11
BE
Bloom Energy Corporation
1059.14%
77.05 B
$ 270.89
United States
Industrials
12
MU
Micron Technology, Inc.
1017.1%
1.10 T
$ 975.56
United States
Technology
13
ROMA
Roma Green Finance Limited
966.51%
479.49 M
$ 8.05
Hong Kong
Industrials
14
HYMC
Hycroft Mining Holding Corp...
935.96%
2.16 B
$ 23.62
United States
Basic Materials
15
NUAI
New Era Energy & Digital, Inc.
912.73%†
483.66 M
$ 4.775
United States
Technology
16
STX
Seagate Technology Holdings...
849.37%
185.56 B
$ 820.16
Singapore
Technology
17
TNGX
Tango Therapeutics, Inc.
841.21%
4.80 B
$ 29.46
United States
Healthcare
18
VSAT
Viasat, Inc.
771.56%
11.34 B
$ 83.06
United States
Technology
19
WDC
Western Digital Corporation
771.18%
185.78 B
$ 539
United States
Technology
20
LITE
Lumentum Holdings Inc.
750.84%
56.66 B
$ 728.32
United States
Technology
21
CELC
Celcuity Inc.
722.16%
5.26 B
$ 107.95
United States
Healthcare
22
PL
Planet Labs PBC
690.43%
11.18 B
$ 31.38
United States
Industrials
23
SLGL
Sol-Gel Technologies Ltd.
629.16%
241.94 M
$ 74.01
Israel
Healthcare
24
APPS
Digital Turbine, Inc.
622.16%
1.53 B
$ 12.71
United States
Technology
25
BVC
BitVentures Limited
611.67%†
1.43 B
$ 8.54
Hong Kong
Technology
26
ERAS
Erasca, Inc.
584.07%
5.74 B
$ 18.47
United States
Healthcare
27
ASM
Avino Silver & Gold Mines Ltd.
579.14%
1.15 B
$ 6.57
Canada
Basic Materials
28
BW
Babcock & Wilcox Enterprise...
578.61%
1.75 B
$ 11.74
United States
Industrials
29
SIF
SIFCO Industries, Inc.
573.5%
154.16 M
$ 24.65
United States
Industrials
30
LQDA
Liquidia Corporation
552.31%
7.02 B
$ 78.93
United States
Healthcare
31
INBX
Inhibrx Biosciences, Inc.
539.87%
1.43 B
$ 97.58
United States
Healthcare
32
TTMI
TTM Technologies, Inc.
534.58%
16.20 B
$ 155.98
United States
Technology
33
TE
T1 Energy Inc.
529.41%†
2.39 B
$ 8.56
United States
Industrials
34
ACMR
ACM Research, Inc.
527.94%
6.76 B
$ 97.77
United States
Technology
35
CLYM
Climb Bio, Inc.
523.19%
738.69 M
$ 12.9
United States
Healthcare
36
LASR
nLIGHT, Inc.
508.17%
3.57 B
$ 63.25
United States
Technology
37
WOLF
Wolfspeed, Inc.
503.32%
2.08 B
$ 40
United States
Technology
38
INTC
Intel Corporation
495.2%
604.88 B
$ 120.35
United States
Technology
39
VICR
Vicor Corporation
486.79%
12.90 B
$ 282.95
United States
Technology
40
STTK
Shattuck Labs, Inc.
482.64%
673.33 M
$ 7.05
United States
Healthcare
41
GORO
Gold Resource Corporation
472.07%
207.51 M
$ 1.27
United States
Basic Materials
42
NUTX
Nutex Health Inc.
466.04%
1.35 B
$ 196.53
United States
Healthcare
43
EVC
Entravision Communications ...
462.5%
1.20 B
$ 13.05
United States
Communication Services
44
SIMO
Silicon Motion Technology C...
450.25%
10.20 B
$ 300.71
Hong Kong
Technology
45
BUUU
BUUU Group Limited
445%†
363.95 M
$ 21.8
Hong Kong
Industrials
46
ATRO
Astronics Corporation
438.29%
3.50 B
$ 70.83
United States
Industrials
47
GH
Guardant Health, Inc.
428.74%
22.27 B
$ 167.98
United States
Healthcare
48
VPG
Vishay Precision Group, Inc.
422.97%
1.62 B
$ 121.59
United States
Technology
49
PGEN
Precigen, Inc.
422.22%
2.01 B
$ 5.64
United States
Healthcare
50
CIEN
Ciena Corporation
407.52%
59.80 B
$ 422.46
United States
Technology
51
USAS
Americas Gold and Silver Co...
401.54%
1.65 B
$ 4.89
Canada
Basic Materials
52
SIFY
Sify Technologies Limited
400.65%
1.11 B
$ 15.32
India
Communication Services
53
TDUP
ThredUp Inc.
398.58%
907.16 M
$ 7.03
United States
Consumer Cyclical
54
COGT
Cogent Biosciences, Inc.
396.03%
6.61 B
$ 38.69
United States
Healthcare
55
NKTR
Nektar Therapeutics
392.82%
2.40 B
$ 71.04
United States
Healthcare
56
AGX
Argan, Inc.
392.71%
9.90 B
$ 706.15
United States
Industrials
57
THM
International Tower Hill Mi...
392.57%
616.71 M
$ 2.32
Canada
Basic Materials
58
PHOE
Phoenix Asia Holdings Limited
387.67%†
384.48 M
$ 17.8
Hong Kong
Industrials
59
DBVT
DBV Technologies S.A.
386.77%
936.33 M
$ 15.82
France
Healthcare
60
ENLT
Enlight Renewable Energy Ltd
386.21%
11.78 B
$ 84.26
Israel
Utilities
61
LRCX
Lam Research Corporation
385.1%
439.46 B
$ 351.41
United States
Technology
62
AEVA
Aeva Technologies, Inc.
378.64%
1.62 B
$ 23.98
United States
Technology
63
MXL
MaxLinear, Inc.
375.83%
8.34 B
$ 93.12
United States
Technology
64
ANAB
AnaptysBio, Inc.
374.7%
1.88 B
$ 63.42
United States
Healthcare
65
IMMX
Immix Biopharma, Inc.
370%
736.10 M
$ 10.34
United States
Healthcare
66
AMLX
Amylyx Pharmaceuticals, Inc.
367.26%
2.03 B
$ 18.27
United States
Healthcare
67
RFIL
RF Industries, Ltd.
366.22%
193.26 M
$ 17.81
United States
Industrials
68
VELO
Velo3D, Inc.
365.18%†
465.79 M
$ 15.63
United States
Technology
69
BIOA
BioAge Labs, Inc.
351.44%
1.12 B
$ 25.1
United States
Healthcare
70
DAVE
Dave Inc.
348.8%
4.92 B
$ 387.36
United States
Technology
71
KOD
Kodiak Sciences Inc.
347.1%
2.41 B
$ 38.54
United States
Healthcare
72
HUT
Hut 8 Corp.
343.76%
10.94 B
$ 97.14
United States
Financial Services
73
MNPR
Monopar Therapeutics Inc.
340.1%
655.10 M
$ 97.79
United States
Healthcare
74
OSS
One Stop Systems, Inc.
335.83%
388.63 M
$ 15.69
United States
Technology
75
RLAY
Relay Therapeutics, Inc.
333.72%
4.06 B
$ 18.65
United States
Healthcare
76
AMPX
Amprius Technologies, Inc.
332.87%
1.75 B
$ 12.38
United States
Industrials
77
CYD
China Yuchai International ...
330.46%
1.63 B
$ 43.39
Singapore
Consumer Cyclical
78
RVMD
Revolution Medicines, Inc.
330.09%
40.23 B
$ 189.24
United States
Healthcare
79
DWSN
Dawson Geophysical Company
329.93%
182.90 M
$ 5.89
United States
Energy
80
UAMY
United States Antimony Corp...
329.48%
1.10 B
$ 7.43
United States
Basic Materials
81
AMD
Advanced Micro Devices, Inc.
329.26%
844.36 B
$ 517.82
United States
Technology
82
ABSI
Absci Corporation
328.78%
1.97 B
$ 11.62
United States
Healthcare
83
ARWR
Arrowhead Pharmaceuticals, ...
327.43%
11.83 B
$ 83.99
United States
Healthcare
84
DRTS
Alpha Tau Medical Ltd.
326.77%
1.20 B
$ 13.23
Israel
Healthcare
85
ORKA
Oruka Therapeutics, Inc.
326.69%
5.14 B
$ 85.21
United States
Healthcare
86
SSRM
SSR Mining Inc.
326.46%
6.35 B
$ 30.62
United States
Basic Materials
87
TSEM
Tower Semiconductor Ltd.
324.93%
26.06 B
$ 219.05
Israel
Technology
88
APLD
Applied Digital Corporation
323.85%
9.45 B
$ 33.06
United States
Technology
89
AEHR
Aehr Test Systems, Inc.
322.72%
2.20 B
$ 69.96
United States
Technology
90
GLW
Corning Incorporated
321.3%
169.36 B
$ 196.79
United States
Technology
91
ASX
ASE Technology Holding Co.,...
317.86%
91.86 B
$ 41.87
Taiwan
Technology
92
STRL
Sterling Infrastructure, Inc.
317.78%
21.50 B
$ 700.75
United States
Industrials
93
CIFR
Cipher Digital Inc.
314.91%
8.20 B
$ 20.04
United States
Technology
94
NVTS
Navitas Semiconductor Corpo...
314.33%
3.52 B
$ 14.46
United States
Technology
95
TRVI
Trevi Therapeutics, Inc.
311.24%
2.55 B
$ 17.93
United States
Healthcare
96
DNTH
Dianthus Therapeutics, Inc.
306.64%
5.16 B
$ 94.34
United States
Healthcare
97
DHC
Diversified Healthcare Trust
306.61%
2.23 B
$ 9.23
United States
Real Estate
98
FIX
Comfort Systems USA, Inc.
306.37%
61.27 B
$ 1741.3
United States
Industrials
99
OPTX
Syntec Optics Holdings, Inc.
305.78%
438.04 M
$ 10.875
United States
Technology
100
OUST
Ouster, Inc.
303.56%
3.17 B
$ 49.84
United States
Technology
† Return measured from the start of the stock's current trading history (a recent listing or relisting), not from January 1st.
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q What is the best stock of 2025?
A

RGC (Regencell Bioscience Holdings Limited) is the best performing stock of 2025 with a year-to-date gain of 4,924% from January 1st to today. The top 3 stocks of 2025 are RGC, SNDK, AXTI.

Q What are the top performing stocks in 2025?
A

The top performing stocks in 2025 YTD are: RGC (+4,924%), SNDK (+3,491%), AXTI (+2,485%), MGRT (+2,049%), ABVX (+1,884%). Performance is calculated from January 1, 2025 to the most recent trading day.

Q Which stocks have made the most money in 2025?
A

The biggest stock gainers of 2025 include RGC leading with +4,924%, followed by SNDK (+3,491%) and AXTI (+2,485%). These represent the best investment returns YTD.

Q What sectors are performing best in 2025?
A

In 2025, the best performing sectors based on top stock gains include Healthcare, Technology. The top gainer RGC operates in the Healthcare sector.

Q Which US stocks have the highest YTD returns in 2025?
A

The US stocks with the highest year-to-date returns in 2025 include RGC (+4,924%), SNDK (+3,491%), AXTI (+2,485%). These top YTD gainers are ranked by total return from January 1st to today across NYSE and NASDAQ.

Understanding Year-to-Date Stock Performance

Year-to-date (YTD) performance measures how much a stock's price has changed since January 1st of the current year. This metric is valuable for several reasons:

  • Current Trend Identification: YTD performance reveals which stocks are leading or lagging in the current market cycle, helping identify emerging trends before they become widely recognized.
  • Benchmark Comparison: Compare individual stock performance against market indices like the S&P 500 to assess whether investments are outperforming or underperforming the broader market.
  • Tax Planning: YTD gains and losses are crucial for tax-loss harvesting strategies and estimating potential capital gains tax obligations before year-end.

Factors Driving YTD Performance

Several factors can influence a stock's year-to-date performance:

  • Earnings Reports: Quarterly earnings that beat or miss expectations can significantly impact stock prices throughout the year.
  • Industry Trends: Sector rotation and changing market preferences can drive entire industries higher or lower.
  • Macroeconomic Factors: Interest rates, inflation data, and economic indicators affect stock valuations across the market.
  • Company-Specific News: Product launches, management changes, M&A activity, and regulatory developments can move individual stocks.

Model Your Returns

See exactly how much a YTD top performer would have returned on your investment with our Stock Return Calculator. Planning regular investments? The DCA Calculator shows how dollar-cost averaging into these stocks would have performed.