STOCK TITAN

Alpha Cognition holder buys 123,918 shares

A 10% owner associated with Opaleye Management Inc. disclosed open-market purchases totaling 123,918 ACOG shares over three days.

(Very High)
(Positive)
Form Type
4

Rhea-AI Filing Summary

Alpha Cognition Inc. (ACOG) reported that large shareholder Opaleye Management Inc., through entities it manages, purchased a total of 123,918 shares of Alpha Cognition common stock in open-market or private transactions on September 14–16, 2026. The purchases were made indirectly via Opaleye, L.P. and a separately managed account, and Opaleye Management Inc. disclaims beneficial ownership beyond its pecuniary interest.

Positive

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Insights

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Insider Opaleye Management Inc.
Role 10% Owner
Bought 123,918 shs ($1.06M)
Type Security Shares Price Value
Purchase Common Stock, no par value F5, F1, F6 53,029 $8.5728 $455K
Purchase Common Stock, no par value F1, F6 27,141 $8.40 $228K
Purchase Common Stock, no par value F4, F1, F6 3,375 $8.5424 $29K
Purchase Common Stock, no par value F3, F1, F6 40,373 $8.696 $351K
holding Common Stock, no par value F2, F6 -- -- --
Holdings After Transaction: Common Stock, no par value — 3,172,141 shares (Indirect, By Opaleye, L.P.); Common Stock, no par value — 100,000 shares (Indirect, By Managed Account)
Footnotes (6)
  1. F1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
  2. F2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
  3. F3. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.664 to $8.72. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
  4. F4. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.53 to $8.57. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
  5. F5. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.46 to $8.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
  6. F6. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Total shares purchased 123,918 shares Common stock acquired indirectly by Opaleye-associated entities on September 14–16, 2026
Shares purchased on September 16, 2026 (trade 1) 53,029 shares Common stock at $8.5728 per share, indirect ownership via Opaleye, L.P.
Shares purchased on September 16, 2026 (trade 2) 27,141 shares Common stock at $8.40 per share, indirect ownership via Opaleye, L.P.
Shares purchased on September 15, 2026 3,375 shares Common stock at weighted average $8.5424 per share, prices from $8.53 to $8.57
Shares purchased on September 14, 2026 40,373 shares Common stock at weighted average $8.696 per share, prices from $8.664 to $8.72
Managed Account holdings 100,000 shares Indirectly owned common stock in a separately managed account as of September 14, 2026
Rule 10b5-1 plan status No plan reported Affirmation checkbox for Rule 10b5-1 was not selected for these transactions
weighted average price financial
"The price reported is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
separately managed account financial
"Securities owned by a separately managed account (the "Managed Account")."
A separately managed account (SMA) is a personalized investment portfolio owned by a single investor and run by a professional manager who buys and sells securities on that investor’s behalf. It matters to investors because an SMA offers tailored asset selection, tax handling, and transparency—like hiring a personal chef who prepares meals to your dietary needs rather than sharing a set menu—so you can align holdings with your goals and see exactly what you own.
beneficially own financial
"may be deemed to beneficially own the securities owned directly by the Fund."
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
pecuniary interest financial
"disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider activity did ACOG disclose for Opaleye Management Inc.?

Alpha Cognition disclosed that Opaleye Management Inc., a ten percent owner, reported purchasing 123,918 common shares of ACOG in open-market or private transactions during September 14–16, 2026, through investment entities it manages.

How many ACOG shares were held in the managed account after these transactions?

A separately managed account associated with Opaleye was reported as holding 100,000 ACOG common shares indirectly as of September 14, 2026, according to the Form 4 holding entry.

Were the ACOG insider purchases under a Rule 10b5-1 trading plan?

No. The filing’s Rule 10b5-1 checkbox was not marked, and no footnote indicates that the Alpha Cognition share purchases were made pursuant to a Rule 10b5-1 or other pre-arranged trading plan.

Does Opaleye Management Inc. claim full beneficial ownership of the ACOG shares?

No. Opaleye Management Inc. disclaims beneficial ownership of the reported Alpha Cognition shares except to the extent of its pecuniary interest, and states that the filing should not be construed as an admission of beneficial ownership.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Learn about SEC filing dates
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Opaleye Management Inc.

(Last)(First)(Middle)
ONE BOSTON PLACE, 26TH FLOOR

(Street)
BOSTON MASSACHUSETTS 02108

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Alpha Cognition Inc. [ ACOG ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
09/14/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock, no par value09/14/2026P40,373A$8.696(3)3,088,596IBy Opaleye, L.P.(1)(6)
Common Stock, no par value09/15/2026P3,375A$8.5424(4)3,091,971IBy Opaleye, L.P.(1)(6)
Common Stock, no par value09/16/2026P53,029A$8.5728(5)3,145,000IBy Opaleye, L.P.(1)(6)
Common Stock, no par value09/16/2026P27,141A$8.43,172,141IBy Opaleye, L.P.(1)(6)
Common Stock, no par value100,000IBy Managed Account(2)(6)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
3. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.664 to $8.72. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
4. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.53 to $8.57. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
5. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.46 to $8.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
6. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Opaleye Management Inc., By: /s/ James Silverman, President09/16/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

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