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[Form 4] Agios Pharmaceuticals, Inc. Insider Trading Activity

Filing Impact
(Low)
Filing Sentiment
(Neutral)
Form Type
4
Rhea-AI Filing Summary

Cynthia Smith, a director of Agios Pharmaceuticals (AGIO), reported the vesting/conversion of 2,302 restricted stock units into common shares on 08/11/2025. The RSUs were granted on 08/11/2022 and, per the filing, vest in three equal annual installments beginning 08/11/2023. The transaction is recorded with transaction code M and shows an acquisition at $0 per share.

The filing reports 12,414 common shares beneficially owned directly by the reporting person following the reported transaction. No cash proceeds or sales are shown in the report, indicating this event reflects equity compensation vesting rather than a market sale.

Cynthia Smith, membro del consiglio di Agios Pharmaceuticals (AGIO), ha segnalato la maturazione/conversione di 2,302 unità azionarie vincolate (RSU) in azioni ordinarie il 08/11/2025. Le RSU erano state assegnate il 08/11/2022 e, secondo il deposito, maturano in tre rate annuali uguali a partire dal 08/11/2023. La transazione è registrata con codice M e indica un'acquisizione a $0 per azione.

Il deposito riporta che, a seguito della transazione, la persona che ha presentato la segnalazione detiene direttamente beneficiariamente 12,414 azioni ordinarie. Non sono indicati proventi in contanti né vendite, il che suggerisce che si tratta della maturazione di un compenso in azioni e non di una vendita sul mercato.

Cynthia Smith, directora de Agios Pharmaceuticals (AGIO), informó la maduración/conversión de 2,302 unidades de acciones restringidas (RSU) en acciones ordinarias el 08/11/2025. Las RSU se concedieron el 08/11/2022 y, según la presentación, vencen en tres cuotas anuales iguales a partir del 08/11/2023. La operación aparece con el código de transacción M y muestra una adquisición a $0 por acción.

La presentación señala que, tras la operación, la persona que informa posee directamente, a título beneficiario, 12,414 acciones ordinarias. No se registran ingresos en efectivo ni ventas, lo que indica que este hecho refleja la maduración de una compensación en acciones y no una venta en el mercado.

Cynthia Smith, Agios Pharmaceuticals(AGIO)의 이사는 08/11/2025에 제한주식단위(RSU) 2,302주가 보통주로 베스팅(권리확정)/전환되었음을 보고했습니다. 해당 RSU는 08/11/2022에 부여되었으며 제출서류에 따르면 08/11/2023부터 매년 동일한 비율로 3회에 걸쳐 권리가 확정됩니다. 거래 코드는 M로 기재되어 있으며 주당 취득가는 $0로 표기되어 있습니다.

제출서류는 보고된 거래 이후 해당 보고인이 직접적으로 수익적 소유를 하는 보통주가 12,414주임을 보고하고 있습니다. 현금 수익이나 매도 내역은 없으므로 이 거래는 시장 매도가 아니라 주식 보상(베스팅)에 따른 권리 확정임을 의미합니다.

Cynthia Smith, administratrice d'Agios Pharmaceuticals (AGIO), a déclaré la conversion liée au vesting de 2,302 unités d'actions restreintes (RSU) en actions ordinaires le 08/11/2025. Les RSU avaient été attribuées le 08/11/2022 et, d'après le dépôt, elles s'acquièrent en trois versements annuels égaux à partir du 08/11/2023. La transaction est enregistrée sous le code M et indique une acquisition à $0 par action.

Le dépôt indique qu'après la transaction, la personne déclarante détient directement, à titre bénéficiaire, 12,414 actions ordinaires. Aucune contrepartie en espèces ni vente n'est mentionnée, ce qui laisse supposer qu'il s'agit de la maturation d'une rémunération en actions et non d'une vente sur le marché.

Cynthia Smith, Direktorin von Agios Pharmaceuticals (AGIO), meldete die Vesting/Umwandlung von 2,302 Restricted Stock Units in Stammaktien am 08/11/2025. Die RSUs wurden am 08/11/2022 gewährt und laut Einreichung beginnen die Vesting-Zeitpunkte am 08/11/2023 und erfolgen in drei gleichen jährlichen Tranchen. Die Transaktion ist mit dem Code M vermerkt und weist einen Erwerb zu $0 je Aktie aus.

Die Einreichung gibt an, dass die meldende Person nach der Transaktion direkt wirtschaftlich begünstigt 12,414 Stammaktien besitzt. Es werden weder Barauszahlungen noch Verkäufe angegeben, was darauf hinweist, dass es sich um das Vesting von aktienbasierter Vergütung und nicht um einen Marktverkauf handelt.

Positive
  • 2,302 restricted stock units converted to common shares
  • Beneficial direct holdings increased to 12,414 shares
Negative
  • None.

Insights

TL;DR: Director RSU vesting added 2,302 shares; routine compensation event with limited immediate valuation impact.

The Form 4 shows a conversion/vesting of 2,302 restricted stock units into common shares at $0, increasing direct holdings to 12,414 shares. There is no sale or cash consideration reported, so this is a non-dilutive compensation recognition for the individual rather than a liquidity event. Absent larger insider sales, dilution, or other disclosures, this transaction is unlikely to materially change the company's near-term financial picture.

TL;DR: Vesting follows disclosed award schedule; transaction aligns with director retention practices and shows no insider selling.

The RSUs were originally granted on 08/11/2022 and vest in three equal annual installments beginning 08/11/2023, as stated in the filing. The report uses transaction code M and records acquisition at $0, consistent with issuance/vesting of equity compensation. This filing signals routine governance of director compensation rather than any governance concern or change in insider intent to sell.

Cynthia Smith, membro del consiglio di Agios Pharmaceuticals (AGIO), ha segnalato la maturazione/conversione di 2,302 unità azionarie vincolate (RSU) in azioni ordinarie il 08/11/2025. Le RSU erano state assegnate il 08/11/2022 e, secondo il deposito, maturano in tre rate annuali uguali a partire dal 08/11/2023. La transazione è registrata con codice M e indica un'acquisizione a $0 per azione.

Il deposito riporta che, a seguito della transazione, la persona che ha presentato la segnalazione detiene direttamente beneficiariamente 12,414 azioni ordinarie. Non sono indicati proventi in contanti né vendite, il che suggerisce che si tratta della maturazione di un compenso in azioni e non di una vendita sul mercato.

Cynthia Smith, directora de Agios Pharmaceuticals (AGIO), informó la maduración/conversión de 2,302 unidades de acciones restringidas (RSU) en acciones ordinarias el 08/11/2025. Las RSU se concedieron el 08/11/2022 y, según la presentación, vencen en tres cuotas anuales iguales a partir del 08/11/2023. La operación aparece con el código de transacción M y muestra una adquisición a $0 por acción.

La presentación señala que, tras la operación, la persona que informa posee directamente, a título beneficiario, 12,414 acciones ordinarias. No se registran ingresos en efectivo ni ventas, lo que indica que este hecho refleja la maduración de una compensación en acciones y no una venta en el mercado.

Cynthia Smith, Agios Pharmaceuticals(AGIO)의 이사는 08/11/2025에 제한주식단위(RSU) 2,302주가 보통주로 베스팅(권리확정)/전환되었음을 보고했습니다. 해당 RSU는 08/11/2022에 부여되었으며 제출서류에 따르면 08/11/2023부터 매년 동일한 비율로 3회에 걸쳐 권리가 확정됩니다. 거래 코드는 M로 기재되어 있으며 주당 취득가는 $0로 표기되어 있습니다.

제출서류는 보고된 거래 이후 해당 보고인이 직접적으로 수익적 소유를 하는 보통주가 12,414주임을 보고하고 있습니다. 현금 수익이나 매도 내역은 없으므로 이 거래는 시장 매도가 아니라 주식 보상(베스팅)에 따른 권리 확정임을 의미합니다.

Cynthia Smith, administratrice d'Agios Pharmaceuticals (AGIO), a déclaré la conversion liée au vesting de 2,302 unités d'actions restreintes (RSU) en actions ordinaires le 08/11/2025. Les RSU avaient été attribuées le 08/11/2022 et, d'après le dépôt, elles s'acquièrent en trois versements annuels égaux à partir du 08/11/2023. La transaction est enregistrée sous le code M et indique une acquisition à $0 par action.

Le dépôt indique qu'après la transaction, la personne déclarante détient directement, à titre bénéficiaire, 12,414 actions ordinaires. Aucune contrepartie en espèces ni vente n'est mentionnée, ce qui laisse supposer qu'il s'agit de la maturation d'une rémunération en actions et non d'une vente sur le marché.

Cynthia Smith, Direktorin von Agios Pharmaceuticals (AGIO), meldete die Vesting/Umwandlung von 2,302 Restricted Stock Units in Stammaktien am 08/11/2025. Die RSUs wurden am 08/11/2022 gewährt und laut Einreichung beginnen die Vesting-Zeitpunkte am 08/11/2023 und erfolgen in drei gleichen jährlichen Tranchen. Die Transaktion ist mit dem Code M vermerkt und weist einen Erwerb zu $0 je Aktie aus.

Die Einreichung gibt an, dass die meldende Person nach der Transaktion direkt wirtschaftlich begünstigt 12,414 Stammaktien besitzt. Es werden weder Barauszahlungen noch Verkäufe angegeben, was darauf hinweist, dass es sich um das Vesting von aktienbasierter Vergütung und nicht um einen Marktverkauf handelt.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Smith Cynthia

(Last) (First) (Middle)
C/O AGIOS PHARMACEUTICALS, INC.
88 SIDNEY STREET

(Street)
CAMBRIDGE MA 02139

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
AGIOS PHARMACEUTICALS, INC. [ AGIO ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
08/11/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common stock 08/11/2025 M 2,302 A $0 12,414 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted stock units (1) 08/11/2025 M 2,302 (2) (2) Common stock 2,302 $0 0 D
Explanation of Responses:
1. Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
2. The restricted stock units were granted on August 11, 2022. Beginning on August 11, 2023, the shares underlying the restricted stock units will vest in three equal annual installments.
Remarks:
/s/ William Cook, as attorney-in-fact for Cynthia Smith 08/13/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Cynthia Smith report on Form 4 for AGIO?

She reported the vesting/conversion of 2,302 restricted stock units into common shares on 08/11/2025, increasing direct holdings to 12,414 shares.

How many RSUs vested and when were they granted?

The filing shows 2,302 RSUs related to a grant dated 08/11/2022, with vesting in three equal annual installments beginning 08/11/2023.

Did Cynthia Smith sell any AGIO shares in this transaction?

No. The Form 4 shows an acquisition/vesting at $0 and does not report any dispositions or sales.

What is Cynthia Smith's role at Agios Pharmaceuticals?

The filing identifies Cynthia Smith as a Director of Agios Pharmaceuticals (AGIO).

What transaction code and price are shown in the filing?

The transaction is recorded with code M and a price of $0 per share.
Agios Pharmaceuticals Inc

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