Welcome to our dedicated page for Agios Pharmaceuticals SEC filings (Ticker: AGIO), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Agios Pharmaceuticals, Inc. filings document the regulatory record of a Delaware, Nasdaq-listed commercial-stage biopharmaceutical company focused on rare diseases and hematology. Its 8-K reports furnish operating results, product revenue updates for PYRUKYND® and AQVESME™, business highlights, investor presentations, and Regulation FD disclosures tied to mitapivat commercialization, clinical programs, and regulatory interactions.
Proxy and current-report filings cover annual-meeting proposals, director elections, board-class structure, committee assignments, stockholder voting matters, and compensatory arrangements for directors. Other disclosures address board appointments, pharmacovigilance communications involving PYRUKYND, exhibit filings, and Inline XBRL cover-page data.
Agios Pharmaceuticals, Inc. (Nasdaq: AGIO) filed an 8-K announcing the election of Jay Backstrom, M.D., MPH, to its Board of Directors. The Board approved his appointment on 3 July 2025, effective 8 July 2025, as a Class III director serving until the 2028 annual meeting.
Compensation package under the non-employee director policy:
- Annual cash retainers: $50,000 for board service and $7,500 for Science & Technology Committee duties.
- Equity awards effective 8 July 2025: (i) non-statutory stock option with a Black-Scholes grant-date value of $472,500; (ii) restricted stock units valued at $157,500. The option strike price equals the closing market price on the grant date. Vesting: 25 % of options after one year, remainder monthly over 36 months; RSUs vest one-third annually over three years.
- Standard reimbursement of reasonable travel expenses.
Dr. Backstrom will also sign the company’s standard indemnification agreement. The filing states there are no related-party transactions or other arrangements connected to his selection.
The disclosure is limited to governance matters; it does not include financial results or operational updates.
Schedule 13G filing: Bellevue Group AG and its wholly-owned subsidiary Bellevue Asset Management AG have disclosed a new beneficial ownership position in Agios Pharmaceuticals, Inc. (NASDAQ: AGIO).
- Stake size: 3,515,150 common shares, representing 6.1 % of the outstanding class as of the triggering date 06 / 01 / 2025.
- Voting & dispositive power: The reporting persons hold shared voting and dispositive power over the entire position; they report zero sole voting/dispositive power.
- Reporting entities: Bellevue Group AG (parent holding company, Switzerland) and Bellevue Asset Management AG (investment manager, Switzerland) filed jointly.
- Purpose: The securities were acquired and are held in the ordinary course of business, not for the purpose of influencing control, as certified in Item 10.
- Form details: Filed 07 / 07 / 2025 under Rule 13d-1(b); CUSIP 00847X104; security class – common stock.
This disclosure introduces Bellevue as a >5 % institutional holder in Agios. While no strategic intentions are indicated, the filing may signal incremental institutional confidence and can affect perceptions of the shareholder base composition.
James William Burns, Chief Legal Officer of Agios Pharmaceuticals (AGIO), reported significant insider transactions on June 24, 2025:
- Acquired 6,000 shares through the vesting of Performance Share Units (PSUs) at $0 exercise price
- Subsequently sold 2,799 shares at $33.54 per share to cover tax withholding obligations
- Following these transactions, Burns now directly owns 28,650 shares
The PSUs were originally granted on March 1, 2023, with 50% vesting upon achievement of a research milestone and 50% upon a regulatory milestone. The reported transaction reflects the vesting of the first 50% as the research milestone was met. The share sale was executed under a pre-established Rule 10b5-1 trading plan, providing an affirmative defense against insider trading liability.
Agios Pharmaceuticals (AGIO) Chief Medical Officer Sarah Gheuens reported significant insider transactions on June 24, 2025. The transactions involved performance share units (PSUs) and common stock:
- 6,000 PSUs converted to common stock upon achieving a specified research milestone
- 2,909 shares were automatically sold at $33.54 per share to cover tax obligations
- Following the transactions, Gheuens holds 56,988 shares directly
The PSUs were originally granted on March 1, 2023, with 50% vesting upon achievement of a research milestone (now met) and 50% contingent on a future regulatory milestone. The share sale was executed under a pre-established 10b5-1 trading plan, demonstrating compliance with insider trading regulations. This transaction suggests positive progress in the company's research initiatives, as evidenced by the milestone achievement triggering the PSU conversion.
Agios Pharmaceuticals (AGIO) Chief Financial Officer Cecilia Jones reported significant insider transactions on June 24, 2025. The transactions involved the vesting of performance share units (PSUs) and subsequent share disposals:
- Acquired 6,000 shares through the vesting of PSUs at $0 exercise price
- Sold 1,780 shares at $33.54 per share to cover tax withholding obligations
- Retained beneficial ownership of 30,049 shares following the transactions
The PSU vesting was triggered by achieving a specified research milestone, representing 50% of the original PSU grant from March 1, 2023. The remaining 50% will vest upon meeting a regulatory milestone. The share sale was executed under a pre-established Rule 10b5-1 trading plan, providing an affirmative defense against insider trading liability.
Agios Pharmaceuticals (AGIO) Chief Commercial Officer Tsveta Milanova reported significant insider transactions on June 24, 2025. The transactions involved performance share units (PSUs) and common stock:
- 6,000 PSUs converted to common stock upon achieving a specified research milestone, representing 50% of the total PSU grant from March 1, 2023
- 2,770 shares were subsequently sold at $33.54 per share to cover tax withholding obligations
- Following these transactions, Milanova holds 26,122 shares directly
The share sale was executed under a pre-established 10b5-1 trading plan. The remaining 50% of PSUs will vest upon achievement of a specified regulatory milestone. The transactions reflect standard executive compensation practices and planned tax-related sales rather than discretionary trading decisions.
Agios Pharmaceuticals (NASDAQ: AGIO) filed a Form 4 disclosing CEO Brian Goff’s June 24 2025 equity transactions.
- PSU vesting: 25,527 and 12,750 shares (total 38,277) converted to common stock at $0 cost.
- Automatic sales for tax-withholding: 12,471 and 6,229 shares sold at $33.54, generating roughly $0.63 million.
- Net change: Beneficial ownership rose by 19,577 shares to 111,922, a ~21 % increase versus the pre-vesting position.
- Sales executed under pre-arranged Rule 10b5-1 instructions; no discretionary selling.
The filing is routine and contains no operational, financial or strategic updates.