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Alto Neuroscience (ANRO) grants $6M retention to new president and CFO

(Moderate)
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Alto Neuroscience, Inc. (ANRO) announced a leadership change effective August 26, 2026. The Board promoted Nicholas C. Smith, previously Chief Financial Officer and Chief Business Officer, to President and Chief Financial Officer. Amit Etkin, M.D., Ph.D. remains Chief Executive Officer and continues to serve as the principal executive officer, while Mr. Smith is the principal financial officer.

Under a new Promotion and Retention Agreement, Mr. Smith is entitled to a cash Retention Payment totaling $6,000,000, with $3,000,000 payable within ten days of August 26, 2026 and $3,000,000 on the twelve-month anniversary of that date, subject to standard deductions and withholdings. If his employment ends for any reason, or for Cause by the company, before the two-year Retention Date, any unpaid portion is forfeited and any paid portion is subject to recoupment within 30 days, except when the company terminates him without Cause or his employment ends due to death or Disability, in which case any unpaid portion will be paid.

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Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Governance
Key personnel changes including departures, elections, or appointments of directors and executive officers.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, or exhibit attachments filed with this report.
Total Retention Payment $6,000,000 Cash Retention Payment under Promotion and Retention Agreement for Nicholas C. Smith
First Retention Installment $3,000,000 Payable within ten days of the August 26, 2026 Effective Date
Second Retention Installment $3,000,000 Payable on the twelve-month anniversary of the August 26, 2026 Effective Date
Retention Period Two-year anniversary of August 26, 2026 Date used as the Retention Date for forfeiture and recoupment provisions
Repayment Deadline 30 days Time for Nicholas C. Smith to repay prior retention amounts after employment ends before Retention Date (except certain terminations)
Effective Date August 26, 2026 Date Mr. Smith’s promotion and Promotion and Retention Agreement became effective
Retention Payment financial
"the Company has agreed to pay Mr. Smith a cash retention payment (the “Retention Payment”)"
Cause regulatory
"terminated by the Company for Cause (as such term is defined in the Offer Letter)"
Disability regulatory
"terminates due to his death or Disability (as such term is defined in the Offer Letter)"
principal executive officer regulatory
"Dr. Etkin serves as the Company’s principal executive officer"
The principal executive officer is the highest-ranking manager who leads a company’s overall strategy, operations and public communication—often acting like the captain of a ship who sets direction and makes final calls. Investors watch this person because their decisions, credibility and ability to deliver results shape company performance, risk and market confidence, and changes in that role can directly affect stock value and corporate accountability.
principal financial officer regulatory
"Mr. Smith serves as the Company’s principal financial officer"
The principal financial officer is the senior executive who runs a company's financial operations: preparing and certifying financial reports, managing accounting controls, budgets and cash flow, and advising on financial strategy. Investors care about this role because its competence affects how trustworthy the company’s numbers are, how well it manages risk and capital needs, and the credibility of forecasts—like the chief navigator steering a firm's financial course.

FAQ

What executive leadership change did Alto Neuroscience (ANRO) announce on August 26, 2026?

Alto Neuroscience promoted Nicholas C. Smith to President and Chief Financial Officer effective August 26, 2026. Amit Etkin, M.D., Ph.D. remains Chief Executive Officer and continues as the company’s principal executive officer, while Mr. Smith serves as principal financial officer.

How much is the retention payment for Alto Neuroscience (ANRO) President and CFO Nicholas C. Smith?

Under his Promotion and Retention Agreement, Nicholas C. Smith is entitled to a total Retention Payment of $6,000,000, payable in two equal installments of $3,000,000 each, subject to standard deductions and withholdings.

When will Alto Neuroscience (ANRO) pay the retention installments to Nicholas C. Smith?

Alto Neuroscience will pay Nicholas C. Smith $3,000,000 within ten days of August 26, 2026 and another $3,000,000 on the twelve-month anniversary of that Effective Date, subject to standard deductions and withholdings.

What happens to the retention payment if Nicholas C. Smith leaves Alto Neuroscience (ANRO) before the Retention Date?

If Nicholas C. Smith’s employment ends for any reason, including resignation or termination for Cause, before the two-year Retention Date, he forfeits any unpaid portion and must repay any previously paid retention amounts within 30 days of his last day of employment.

Under what circumstances will Alto Neuroscience (ANRO) still pay unpaid retention amounts to Nicholas C. Smith?

If, before the Retention Date, Alto Neuroscience terminates Nicholas C. Smith’s employment without Cause, or his employment ends due to his death or Disability, the company will pay him any unpaid portion of the Retention Payment upon such termination.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Learn about SEC filing dates
0001999480False00019994802026-08-262026-08-26

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
_____________________
FORM 8-K
_____________________

CURRENT REPORT
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): August 26, 2026
_____________________
ALTO NEUROSCIENCE, INC.
(Exact Name of Registrant as Specified in its Charter)
_____________________
Delaware
 001-41944
83-4210124
(State or Other Jurisdiction
of Incorporation)
(Commission
File Number)
(IRS Employer
Identification No.)
650 Castro Street, Suite 450, Mountain View, CA
94041
(Address of principal executive offices)(Zip Code)
Registrant’s telephone number, including area code: (650) 200-0412
N/A
(Former name or former address, if changed since last report)
_____________________
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
oWritten communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
oSoliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
oPre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
oPre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))


Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading
Symbol(s)
Name of each exchange
on which registered
Common Stock, $0.0001 par value per shareANRONew York Stock Exchange

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company x
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o



Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On August 26, 2026 (the “Effective Date”), the Board of Directors (the “Board”) of Alto Neuroscience, Inc. (the “Company”) promoted Nicholas C. Smith, the Company’s Chief Financial Officer and Chief Business Officer, to the position of President and Chief Financial Officer, effective immediately. In connection with Mr. Smith’s promotion, as of August 26, 2026, Amit Etkin, M.D., Ph.D., the Company’s President and Chief Executive Officer, continues in his role as the Company’s Chief Executive Officer, but no longer holds the office of the President. Dr. Etkin serves as the Company’s principal executive officer and Mr. Smith serves as the Company’s principal financial officer.

In connection with Mr. Smith’s promotion to President and Chief Financial Officer, on the Effective Date, the Company entered into a promotion and retention agreement (the “Promotion and Retention Agreement”) with Mr. Smith. Pursuant to the Promotion and Retention Agreement, the Company has agreed to pay Mr. Smith a cash retention payment (the “Retention Payment”) which shall be paid as follows: (1) $3,000,000 payable within ten days of the Effective Date and (2) $3,000,000 payable on the twelve-month anniversary of the Effective Date. Both portions of the Retention Payment are subject to standard deductions and withholdings.

If Mr. Smith’s employment with the Company terminates for any reason, including Mr. Smith’s resignation, or is terminated by the Company for Cause (as such term is defined in the Offer Letter, as amended, between Mr. Smith and the Company (the “Offer Letter”)), in either case prior to the two-year anniversary of the Effective Date (the “Retention Date”), Mr. Smith will not be entitled to any unpaid portion of the Retention Payment, and any previously paid portion of the Retention Payment will be subject to recoupment by the Company, with Mr. Smith required to repay such amounts to the Company within 30 days following his last day of employment. If, prior to the Retention Date, the Company terminates Mr. Smith's employment without Cause, or his employment terminates due to his death or Disability (as such term is defined in the Offer Letter), the Company will pay to Mr. Smith any unpaid portion of the Retention Payment upon such termination.

Biographical information for Mr. Smith is contained in the Company’s definitive proxy statement, filed with the U.S. Securities and Exchange Commission on March 26, 2026. There are no arrangements or understandings between Mr. Smith and any other persons, pursuant to which he was appointed to the position of President, there are no family relationships between Mr. Smith and any of the Company’s directors or other executive officers, and there are no transactions between Mr. Smith and the Company that would be required to be disclosed pursuant to Item 404(a) of Regulation S-K.

The foregoing summary is qualified in its entirety by reference to the full text of the Promotion and Retention Agreement, a copy of which is attached hereto as Exhibit 10.1 and is incorporated into this Item 5.02 by reference.



Item 9.01    Financial Statements and Exhibits.

(d)Exhibits.
Exhibit No.Description
10.1
Promotion and Retention Agreement, dated August 26, 2026, between Alto Neuroscience, Inc. and Nicholas C. Smith
104Cover Page Interactive Data File (embedded within the Inline XBRL document).



SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
ALTO NEUROSCIENCE, INC.
Dated: August 27, 2026By:/s/ Amit Etkin
Amit Etkin, M.D., Ph.D.
Chief Executive Officer

Filing Exhibits & Attachments

4 documents