Welcome to our dedicated page for Annovis Bio SEC filings (Ticker: ANVS), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Annovis Bio, Inc. filings document the regulatory record of a clinical-stage biotechnology company developing buntanetap for Alzheimer’s disease, Parkinson’s disease, and related neurodegenerative conditions. Recent Form 8-K reports cover operating results, Regulation FD materials, clinical and regulatory updates, material-event disclosure, exhibits, and changes in executive finance leadership.
Proxy materials describe annual-meeting proposals, director elections, stockholder voting procedures, board governance, and the company’s common stock structure. The filings also identify ANVS common stock as a New York Stock Exchange-listed security and provide capital-structure and governance disclosures relevant to the company’s development-stage business.
Annovis Bio, Inc. appointed Mark Guerin, age 57, as its new Chief Financial Officer effective September 25, 2025. He previously served as CFO of Onconova Therapeutics, now Traws Pharma, Inc., from 2016 through February 2025, and holds a bachelor’s degree in accounting plus CPA, CMA, and CFM certifications.
His compensation package includes an annual base salary of $450,000, an annual target bonus of 40%, stock options to purchase 200,000 shares of Annovis Bio common stock, six months of severance pay, and eligibility to participate in the company’s standard employee benefit plans. The company stated there are no related-party transactions requiring disclosure between Annovis Bio and Mr. Guerin and issued a press release announcing his appointment.
Michael B. Hoffman, a director of Annovis Bio, Inc. (ANVS), reported purchases of company common stock on 08/29/2025. He acquired three blocks of 5,000 shares each at prices of $2.28, $2.29, and $2.30, increasing his direct holdings from 1,469,929 to 1,479,929 shares. The filing also discloses indirect beneficial ownership of 223,357 shares held in the 2018 Jane and Michael Hoffman Descendants Trust, over which he has voting and investment power. The Form 4 is signed by an attorney-in-fact on behalf of the reporting person.
Michael B. Hoffman, a director of Annovis Bio, Inc. (ANVS), reported multiple open-market purchases of common stock on 08/19/2025. The Form 4 shows four acquisitions totaling 18,645 shares at prices ranging from $2.57 to $2.60, recorded as purchases (code A). After these transactions Mr. Hoffman directly beneficially owned 1,464,929 shares, and 223,357 shares were held indirectly in the 2018 Jane and Michael Hoffman Descendants Trust, over which he has voting and investment power.
The filing was signed by an attorney-in-fact on 08/20/2025. The form identifies Mr. Hoffman as a director and a single reporting person for this report.
Annovis Bio, Inc. reported that Andrew Walsh, its Vice President of Finance and Principal Financial Officer, resigned effective August 22, 2025. The company stated that his resignation did not result from any disagreement over operations, policies, or practices.
On August 15, 2025, the board unanimously appointed Chief Executive Officer Maria Maccecchini to also serve as Acting Chief Financial Officer. Annovis Bio indicated it is actively searching for a permanent Chief Financial Officer to fill the role.
Annovis Bio reported a cash balance of $17.1 million as of June 30, 2025 and a six-month net loss of $11.8 million, leaving an accumulated deficit of $146.6 million. Operating loss for the six months was $12.6 million versus $15.6 million in the prior year period. Net proceeds of $19.3 million were generated from a February 2025 underwritten offering with ThinkEquity, and the company sold an additional $0.5 million of common stock under its December 2024 ATM during the six months.
The filing discloses that management has concluded substantial doubt exists about the company’s ability to continue as a going concern and is pursuing additional capital through equity or debt financings, collaborations or cost deferrals. On the clinical front, Annovis initiated its FDA-cleared pivotal ANVS-25001 Phase 3 trial in early Alzheimer’s disease in February 2025 and describes prior topline PD and AD data and alignment with the FDA on a development path for buntanetap.
Annovis Bio, Inc. furnished a Current Report on Form 8-K stating that on August 12, 2025 the company issued a press release announcing its financial results for the second quarter ended June 30, 2025 and providing a corporate update. The filing indicates the press release is included as Exhibit 99.1 and also includes the Cover Page Interactive Data File as Exhibit 104. The registrant is identified as an emerging growth company and has elected not to use the extended transition period for new or revised accounting standards.
The 8-K text itself does not present the numerical results or additional operational details; those items are contained in the referenced press release furnished as an exhibit.
Annovis Bio, Inc. (NYSE: ANVS) filed a Form 8-K reporting the outcome of its 2025 virtual Annual Meeting held on 17 June 2025.
Quorum: 11,588,981 shares (59.47% of shares outstanding).
Proposal 1 – Election of Directors (one-year terms):
- Maria Maccecchini – 4,216,112 FOR / 173,438 WITHHELD / 7,199,431 broker non-votes
- Michael Hoffman – 4,182,806 FOR / 206,744 WITHHELD / 7,199,431 broker non-votes
- Claudine Bruck – 4,041,007 FOR / 348,543 WITHHELD / 7,199,431 broker non-votes
- Reid McCarthy – 4,202,391 FOR / 187,159 WITHHELD / 7,199,431 broker non-votes
- Mark White – 3,780,238 FOR / 609,312 WITHHELD / 7,199,431 broker non-votes
Proposal 2 – Ratification of Independent Auditor: Ernst & Young LLP ratified with 11,382,542 FOR, 187,959 AGAINST, 18,480 ABSTAIN.
All proposals passed; no additional matters were presented.
Annovis Bio, Inc. (NYSE: ANVS) filed an 8-K on June 19, 2025 to disclose that the New York Stock Exchange has accepted the company’s previously submitted listing-compliance plan. The plan was required after Annovis fell out of compliance with NYSE continued-listing standards; acceptance removes the immediate risk of delisting and starts a defined remediation timetable. The 8-K furnishes, but does not file, a press release (Exhibit 99.1) announcing the NYSE decision. No financial statements, earnings data or major transactions were included, and the disclosure is made solely under Item 7.01 (Regulation FD) with no impact on historical financial reporting.
Investors should note that, while acceptance is a constructive step, Annovis must still meet the milestones outlined in the compliance plan to regain full compliance. The filing contains no new operational or financial metrics.
Annovis Bio (ANVS) Vice President of Finance Andrew Walsh reported a new acquisition of company shares on Form 4. The transaction details include:
- Acquired 500 shares of Common Stock
- Purchase price: $2.90 per share
- Transaction date: June 16, 2025
- Total transaction value: $1,450
- Ownership type: Direct
Following this transaction, Walsh holds 500 shares directly. The purchase represents an initial position for the executive, as no prior holdings were reported. The transaction was reported within the required two-business-day filing window, with the Form 4 being filed on June 28, 2025. No derivative securities were involved in this transaction.