STOCK TITAN

Avalo Therapeutics (AVTX) CMO option exercises and 108,234-share sale

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Avalo Therapeutics Chief Medical Officer Doyle Mittie reported option exercises and related share sales in Avalo Therapeutics, Inc. common stock. On May 5–6, 2026, she exercised stock options covering 108,234 shares at strike prices of $8.04 and $12.65 per share and sold 108,234 shares in open-market transactions.

The sales occurred at prices ranging from $16.00 to about $22.88, executed in multiple trades. According to a footnote, all transactions were carried out under a pre-arranged Rule 10b5-1 trading plan adopted on November 13, 2025, indicating they were scheduled in advance rather than timed discretionarily.

Positive

  • None.

Negative

  • None.
Insider Doyle Mittie
Role Chief Medical Officer
Sold 108,234 shs ($2.23M)
Type Security Shares Price Value
Exercise Stock Option (Right to Buy) 77,905 $0.00 --
Exercise Stock Option (Right to Buy) 28,650 $0.00 --
Exercise Common Stock 77,905 $12.65 $985K
Exercise Common Stock 28,650 $8.04 $230K
Sale Common Stock 27,538 $18.0262 $496K
Sale Common Stock 5,000 $19.6502 $98K
Sale Common Stock 44,944 $21.1968 $953K
Sale Common Stock 19,015 $22.406 $426K
Sale Common Stock 10,058 $22.88 $230K
Exercise Stock Option (Right to Buy) 1,000 $0.00 --
Exercise Stock Option (Right to Buy) 679 $0.00 --
Exercise Common Stock 1,000 $12.65 $13K
Exercise Common Stock 679 $8.04 $5K
Sale Common Stock 1,679 $16.00 $27K
Holdings After Transaction: Stock Option (Right to Buy) — 131,625 shares (Direct, null); Common Stock — 81,527 shares (Direct, null)
Footnotes (1)
  1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 13, 2025. The reported securities were sold in multiple transactions at prices ranging from $18.00 to $18.97. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range. The reported securities were sold in multiple transactions at prices ranging from $19.08 to $19.99. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range. The reported securities were sold in multiple transactions at prices ranging from $20.75 to $21.69. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range. The reported securities were sold in multiple transactions at prices ranging from $21.83 to $22.80. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range. The stock option vests twenty-five percent (25%) on July 15, 2025 and the remainder will vest in equal monthly installments over the following three (3) years, subject to the Reporting Person's continued service on each such vesting date. The stock option vests twenty-five percent (25%) on January 28, 2026 and the remainder will vest in equal monthly installments over the following three (3) years, subject to the Reporting Person's continued service on each such vesting date.
Shares sold 108,234 shares Total open-market sales reported in Form 4
Shares exercised 108,234 shares Stock options converted to common stock
Sale price range $16.00 to about $22.88 per share Reported common stock sale prices
Option strike price 1 $8.04 per share Exercise price for one stock option grant
Option strike price 2 $12.65 per share Exercise price for another stock option grant
10b5-1 plan adoption date November 13, 2025 Date CMO adopted trading plan for these transactions
Option expiration 1 January 28, 2035 Expiration date for $8.04 strike option
Option expiration 2 July 15, 2034 Expiration date for $12.65 strike option
Rule 10b5-1 trading plan regulatory
"transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
Stock Option (Right to Buy) financial
"security_title: "Stock Option (Right to Buy)" with underlying common stock"
derivative exercise/conversion financial
"transaction_action: "derivative exercise/conversion" for M-coded transactions"
open-market sale financial
"transaction_action: "open-market sale" for S-coded transactions"
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
vesting financial
"The stock option vests twenty-five percent (25%) on July 15, 2025 and the remainder will vest"
Vesting is the process by which you earn full ownership of something, like company stock or a retirement benefit, over time. It’s like earning the right to keep a gift piece by piece the longer you stay with a company, making sure employees stay committed before they receive all the benefits.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Doyle Mittie

(Last)(First)(Middle)
C/O AVALO THERAPEUTICS, INC.
1500 LIBERTY RIDGE DRIVE, SUITE 321

(Street)
WAYNE PENNSYLVANIA 19087

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Avalo Therapeutics, Inc. [ AVTX ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
Chief Medical Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
05/05/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock05/05/2026M(1)1,000A$12.654,622D
Common Stock05/05/2026M(1)679A$8.045,301D
Common Stock05/05/2026S(1)1,679D$163,622D
Common Stock05/06/2026M(1)77,905A$12.6581,527D
Common Stock05/06/2026M(1)28,650A$8.04110,177D
Common Stock05/06/2026S(1)27,538D$18.0262(2)82,639D
Common Stock05/06/2026S(1)5,000D$19.6502(3)77,639D
Common Stock05/06/2026S(1)44,944D$21.1968(4)32,695D
Common Stock05/06/2026S(1)19,015D$22.406(5)13,680D
Common Stock05/06/2026S(1)10,058D$22.883,622D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$12.6505/05/2026M(1)1,000 (6)07/15/2034Common Stock1,000$0209,530D
Stock Option (Right to Buy)$8.0405/05/2026M(1)679 (7)01/28/2035Common Stock679$0147,650D
Stock Option (Right to Buy)$12.6505/06/2026M(1)77,905 (6)07/15/2034Common Stock77,905$0131,625D
Stock Option (Right to Buy)$8.0405/06/2026M(1)28,650 (7)01/28/2035Common Stock28,650$0119,000D
Explanation of Responses:
1. The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 13, 2025.
2. The reported securities were sold in multiple transactions at prices ranging from $18.00 to $18.97. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range.
3. The reported securities were sold in multiple transactions at prices ranging from $19.08 to $19.99. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range.
4. The reported securities were sold in multiple transactions at prices ranging from $20.75 to $21.69. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range.
5. The reported securities were sold in multiple transactions at prices ranging from $21.83 to $22.80. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within such range.
6. The stock option vests twenty-five percent (25%) on July 15, 2025 and the remainder will vest in equal monthly installments over the following three (3) years, subject to the Reporting Person's continued service on each such vesting date.
7. The stock option vests twenty-five percent (25%) on January 28, 2026 and the remainder will vest in equal monthly installments over the following three (3) years, subject to the Reporting Person's continued service on each such vesting date.
/s/ Christopher Sullivan, Attorney-in-Fact05/07/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did Avalo Therapeutics (AVTX) report for Doyle Mittie?

Avalo Therapeutics Chief Medical Officer Doyle Mittie exercised stock options for 108,234 shares and sold 108,234 common shares in open-market trades. The transactions occurred on May 5–6, 2026 as part of a disclosed Rule 10b5-1 trading plan.

At what prices did the Avalo Therapeutics (AVTX) CMO sell shares?

The Avalo Therapeutics CMO’s reported sales occurred at prices between $16.00 and approximately $22.88 per share. Footnotes note multiple trades within narrower ranges, with the company offering to provide detailed price breakdowns upon request to investors or regulators.

How many Avalo Therapeutics (AVTX) shares did the CMO exercise and sell?

The filing shows the CMO exercised stock options covering 108,234 shares of common stock and sold 108,234 shares in open-market transactions. This exercise-and-sell pattern converts option awards into cash without increasing her net common share position from these specific trades.

Were the Avalo Therapeutics (AVTX) insider trades under a Rule 10b5-1 plan?

Yes. A footnote states all reported transactions were effected under a Rule 10b5-1 trading plan adopted on November 13, 2025. Such plans pre-schedule trades, which generally makes the timing appear more routine and less reflective of short-term market views.

What stock options did the Avalo Therapeutics (AVTX) CMO exercise in this Form 4?

The CMO exercised stock options with exercise prices of $8.04 and $12.65 per share, covering a total of 108,234 underlying common shares. Related footnotes describe vesting schedules with 25% vesting on specified dates, followed by monthly vesting over three years.

What does the Form 4 reveal about Avalo Therapeutics (AVTX) option vesting terms?

Footnotes explain certain stock options vest 25% on July 15, 2025 or January 28, 2026, with the remaining 75% vesting in equal monthly installments over three years. Vesting remains contingent on the reporting person’s continued service through each vesting date.