[Form 3] Bicycle Therapeutics plc American Initial Statement of Beneficial Ownership

Rhea-AI Filing Summary

Bicycle Therapeutics plc (BCYC) Form 3 reports that Roger D. Dansey, listed as a Director, filed an initial beneficial ownership statement for the event dated 09/08/2025. The filing states no securities are beneficially owned by the reporting person. The form was signed on 09/10/2025 by an attorney-in-fact.

Positive

• Form 3 filed meeting disclosure obligations for a director
• Disclosure includes event date of 09/08/2025 and signature date 09/10/2025

Negative

• Reporting person holds no beneficial securities as stated in the filing

Insights

Corporate Governance Specialist

Initial director filing shows no disclosed economic stake as of 09/08/2025.

This Form 3 documents the required insider disclosure for Roger D. Dansey as a Director of Bicycle Therapeutics plc. The filing explicitly states "No securities are beneficially owned."

For investors, the key takeaway is that the director reported no direct or indirect holdings at the time of the event, which is unusual for many directors but is a factual reporting item rather than an explanation of intent or future action.

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

DANSEY ROGER D

(Last) (First) (Middle)

C/O BICYCLE THERAPEUTICS PLC

BLOCKS A & B, PORTWAY BUILDING

(Street)

CAMBRIDGE X0 CB21 6GS

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
09/08/2025

3. Issuer Name and Ticker or Trading Symbol
BICYCLE THERAPEUTICS PLC [ BCYC ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

No securities are beneficially owned.

	/s/ Travis Thompson, Attorney-in-Fact	09/10/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What does the BCYC Form 3 filed for Roger D. Dansey disclose?

The Form 3 discloses that Roger D. Dansey, a Director of Bicycle Therapeutics plc (BCYC), reported no securities beneficially owned as of the event date 09/08/2025.

When was the Form 3 for BCYC signed and filed?

The form shows the event date 09/08/2025 and was signed by an attorney-in-fact on 09/10/2025.

Does this Form 3 report any stock options or derivative holdings for BCYC?

No. Table I and Table II in the filing indicate no non-derivative or derivative securities are beneficially owned.

What is the reporting relationship of Roger D. Dansey to BCYC?

The filing identifies Roger D. Dansey as a Director of Bicycle Therapeutics plc.

Is this a joint filing for BCYC Form 3?

No. The filing indicates it was submitted by one reporting person.