[SCHEDULE 13D/A] Chemomab Therapeutics Ltd. American Depositary Share SEC Filing

Rhea-AI Filing Summary

OrbiMed Israel and affiliated entities have filed Amendment No. 5 to Schedule 13D reporting their exit from a significant ownership position in Chemomab Therapeutics Ltd (NASDAQ: CMMB). The filing indicates that following a major transaction, the reporting persons have ceased to be beneficial owners of more than 5% of the company's shares.

Key details of the transaction and current holdings:

• On June 18, 2025, OrbiMed Israel Partners (OIP) sold 1,610,000 American Depositary Shares at $1.10 per ADS
• Current holdings include 131,273 ADSs, 28,817 Warrants, and 809,717 Pre-Funded Warrants
• Total beneficial ownership now represents approximately 4.8% of outstanding shares

The reporting group includes OrbiMed Israel GP Ltd, OrbiMed Israel BioFund GP Limited Partnership, Carl L. Gordon, and Erez Chimovits. The holders maintain registration rights for their remaining securities under a previously established Registration Rights Agreement.

Positive

• None.

Negative

• OrbiMed entities reduced their ownership stake below 5% through sale of 1.61M ADSs at $1.10 per share, representing a significant institutional investor exit

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 5)

Chemomab Therapeutics Ltd.

(Name of Issuer)

Ordinary Shares, no par value. American Depository Shares, each of which represents twenty Ordinary Shares, no par value

(Title of Class of Securities)

16385C104

(CUSIP Number)

OrbiMed Israel BioFund GP LP
5 Hahoshlim St., Building B, 1st Floor
Herzliya Pituach, L3, 4614001
972 73 2822600

OrbiMed Israel GP Ltd.
5 Hahoshlim St., Building B, 1st Floor
Herzliya Pituach, L3, 4614001
972 73 2822600

Erez Chimovits
5 Hahoshlim St., Building B, 1st Floor
Herzliya Pituach, L3, 4614001
972 73 2822600

Carl L. Gordon
5 Hahoshlim St., Building B, 1st Floor
Herzliya Pituach, L3, 4614001
972 73 2822600

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

06/18/2025

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

SCHEDULE 13D

CUSIP No. 16385C104

1

Name of reporting person

ORBIMED ISRAEL BIOFUND GP LIMITED PARTNERSHIP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

ISRAEL

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 969,807.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 969,807.00

11

Aggregate amount beneficially owned by each reporting person

969,807.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

4.8 %

14

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13D

CUSIP No. 16385C104

1

Name of reporting person

ORBIMED ISRAEL GP LTD.

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

ISRAEL

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 969,807.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 969,807.00

11

Aggregate amount beneficially owned by each reporting person

969,807.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

4.8 %

14

Type of Reporting Person (See Instructions)

CO

SCHEDULE 13D

CUSIP No. 16385C104

1

Name of reporting person

CHIMOVITS EREZ

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

ISRAEL

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 969,807.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 969,807.00

11

Aggregate amount beneficially owned by each reporting person

969,807.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

4.8 %

14

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13D

CUSIP No. 16385C104

1

Name of reporting person

GORDON CARL L

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 969,807.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 969,807.00

11

Aggregate amount beneficially owned by each reporting person

969,807.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

4.8 %

14

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13D

Item 1.	Security and Issuer
(a)	Title of Class of Securities: Ordinary Shares, no par value. American Depository Shares, each of which represents twenty Ordinary Shares, no par value
(b)	Name of Issuer: Chemomab Therapeutics Ltd.
(c)	Address of Issuer's Principal Executive Offices: Kiryat Atidim, Building 7, Tel Aviv, ISRAEL , 6158002.
Item 1 Comment: This Amendment No. 5 ("Amendment No. 5") to Schedule 13D supplements and amends the Statement on Schedule 13D of OrbiMed Israel GP Ltd. ("OrbiMed Israel"), OrbiMed Israel BioFund GP Limited Partnership ("OrbiMed BioFund"), Carl L. Gordon ("Gordon"), and Erez Chimovits ("Chimovits") (collectively, the "Reporting Persons") originally filed with the Securities and Exchange Commission (the "SEC") on March 26, 2021, as amended by Amendment No. 1 filed with the SEC on January 5, 2023, Amendment No. 2 filed with the SEC on November 15, 2023, Amendment No. 3 filed with the SEC on March 11, 2024, and Amendment No. 4 filed with the SEC on September 16, 2024. This Amendment No. 5 is being filed to report that following the transactions described in Item 5(c) below, the Reporting Persons ceased to be beneficial owners of more than 5% of the Shares and, as a result, this Amendment No. 5 is an exit filing for the Reporting Persons.
Item 2.	Identity and Background
(a)	OrbiMed Israel, a corporation organized under the laws of Israel. OrbiMed BioFund, a limited partnership organized under the laws of Israel. Carl L. Gordon, a United States citizen. Erez Chimovits, an Israeli citizen.
(b)	5 Hahoshlim Street, Building B, 1st Floor, Herzliya Pituach, Israel 46686.
(c)	OrbiMed Israel is the general partner of certain entities more particularly described in Item 6 below. OrbiMed BioFund is the general partner of a limited partnership as more particularly described in Item 6 below. Carl L. Gordon is a Director of OrbiMed Israel. Erez Chimovits is a Director of OrbiMed Israel.
(d)	Not applicable.
(e)	Not applicable.
(f)	Item 2(a) is incorporated herein by reference.
Item 3.	Source and Amount of Funds or Other Consideration
	Not applicable.
Item 4.	Purpose of Transaction
	The Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either in the open market or in privately negotiated transactions. Similarly, depending on market and other factors, the Reporting Persons may determine to dispose of some or all of the Shares currently owned by the Reporting Persons or otherwise acquired by the Reporting Persons either in the open market or in privately negotiated transactions. Except as set forth in this Schedule 13D, the Reporting Persons have not formulated any plans or proposals which relate to or would result in: (a) the acquisition by any person of additional securities of the Issuer or the disposition of securities of the Issuer, (b) an extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries, (c) a sale or transfer of a material amount of the assets of the Issuer or any of its subsidiaries, (d) any change in the present Board of Directors or management of the Issuer, including any plans or proposals to change the number or term of directors or to fill any existing vacancies on the board, (e) any material change in the Issuer's capitalization or dividend policy of the Issuer, (f) any other material change in the Issuer's business or corporate structure, (g) any change in the Issuer's charter or bylaws or other instrument corresponding thereto or other action which may impede the acquisition of control of the Issuer by any person, (h) causing a class of the Issuer's securities to be deregistered or delisted from a national securities exchange or to cease to be authorized to be quoted in an inter-dealer quotation system of a registered national securities association, (i) a class of equity securities of the Issuer becoming eligible for termination of registration pursuant to Section 12(g)(4) of the Act or (j) any action similar to any of those enumerated above.
Item 5.	Interest in Securities of the Issuer
(a)	The following disclosure is based upon 20,002,293 ADSs outstanding, which amount includes 19,163,759 ADSs as set forth in the Issuer's Current Report on Form 6-K filed with the SEC on May 27, 2025 and gives effect to the additional 838,534 ADSs that would be outstanding following the exercise of presently exercisable Pre-Funded Warrants and warrants to purchase ADSs held by the Reporting Persons ("Warrants"). As of the date of this filing, OIP, a limited partnership organized under the laws of Israel, holds 131,273 ADSs, 28,817 Warrants, and 809,717 Pre-Funded Warrants, constituting approximately 4.8% of the issued and outstanding ADSs, which represents the same percentage of the outstanding Ordinary Shares. OrbiMed BioFund is the general partner of OIP, pursuant to the terms of the limited partnership agreement of OIP, and OrbiMed Israel is the general partner of OrbiMed BioFund, pursuant to the terms of the limited partnership agreement of OrbiMed BioFund. As a result, OrbiMed BioFund and OrbiMed Israel share the power to direct the vote and disposition of the Shares held by OIP and may be deemed, directly or indirectly, including by reason of their mutual affiliation, to be the beneficial owners of the Shares held by OIP. OrbiMed Israel exercises this investment power through an investment committee comprised of Gordon and Chimovits, each of whom disclaims beneficial ownership of the Shares held by OIP.
(b)	Item 5(a) is incorporated by reference herein.
(c)	On June 18, 2025, OIP sold 1,610,000 ADSs at a price of $1.10 per ADS.
(d)	Not applicable.
(e)	As of June 18, 2025, the Reporting Persons are believed to have ceased to be the beneficial owners of more than five percent of the outstanding Shares.
Item 6.	Contracts, Arrangements, Understandings or Relationships With Respect to Securities of the Issuer
	In addition to the relationships between the Reporting Persons described in Items 2 and 5 above, OrbiMed BioFund is the general partner of OIP pursuant to the terms of the limited partnership agreement of OIP. OrbiMed Israel is the general partner of OrbiMed BioFund, pursuant to the terms of the limited partnership agreement of OrbiMed BioFund. Pursuant to these agreements and relationships, OrbiMed Israel and OrbiMed BioFund have discretionary investment management authority with respect to the assets of OIP. Such authority includes the power of OrbiMed BioFund to vote and otherwise dispose of securities held by OIP. The number of outstanding ADSs attributable to OIP is 131,273 ADSs. Additionally, OIP holds 28,817 Warrants and 809,717 Pre-Funded Warrants. OrbiMed BioFund, pursuant to its authority under the limited partnership agreement of OIP, OrbiMed Israel, pursuant to its authority under the limited partnership agreement of OrbiMed BioFund, and Gordon and Chimovits pursuant to their membership on OrbiMed Israel's investment committee, may each be considered to hold indirectly 131,273 ADSs, 28,817 Warrants, and 809,717 Pre-Funded Warrants. Registration Rights Agreement In connection with the Private Placement, OrbiMed BioFund and OrbiMed Israel, pursuant to their authority under the limited partnership agreement of OIP, caused OIP to enter into a Registration Rights Agreement (the "Registration Rights Agreement"), which requires the Issuer to, among other things, file a registration statement on Form F-1 or Form F-3 (subject to the Issuer's eligibility to use each such Form) with respect to the resale of the securities sold in the Private Placement. The Issuer is required to prepare and file such registration statement with the SEC as soon as reasonably practicable, but in no event later than 30 days following the closing of the Private Placement, and to use its commercial best efforts to have the registration statement declared effective as soon as reasonably practicable. The foregoing description of the Registration Rights Agreement does not purport to be complete and is qualified in its entirety by reference to the full text of the Registration Rights Agreement, which is filed as Exhibit 2 and is incorporated herein by reference.
Item 7.	Material to be Filed as Exhibits.
	1. Joint Filing Agreement between Erez Chimovits, Carl L. Gordon, OrbiMed Israel GP Ltd., and OrbiMed Israel BioFund GP Limited Partnership. 2. Form of Registration Rights Agreement (incorporated by reference to Exhibit 99.4 to the Issuer's Current Report on Form 6-K (File No. 001-38807) filed with the SEC on July 25, 2024. https://www.sec.gov/Archives/edgar/data/1534248/000117891324002290/exhibit_99-4.htm

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

ORBIMED ISRAEL BIOFUND GP LIMITED PARTNERSHIP

Signature:	/s/ Carl L. Gordon
Name/Title:	Carl L. Gordon/Director
Date:	06/23/2025

ORBIMED ISRAEL GP LTD.

Signature:	/s/ Carl L. Gordon
Name/Title:	Carl L. Gordon/Director
Date:	06/23/2025

CHIMOVITS EREZ

Signature:	/s/ Erez Chimovits
Name/Title:	Erez Chimovits
Date:	06/23/2025

GORDON CARL L

Signature:	/s/ Carl L. Gordon
Name/Title:	Carl L. Gordon
Date:	06/23/2025

FAQ

What percentage of CMMB shares does OrbiMed Israel currently own?

According to the Schedule 13D/A filing, OrbiMed Israel and related entities now own approximately 4.8% of CMMB's outstanding shares, consisting of 131,273 ADSs, 28,817 Warrants, and 809,717 Pre-Funded Warrants.

Why did OrbiMed file this Schedule 13D/A for CMMB on June 28, 2025?

This Amendment No. 5 was filed as an exit filing because OrbiMed's ownership fell below 5% following a sale of 1,610,000 ADSs at $1.10 per ADS on June 18, 2025, requiring them to report they are no longer beneficial owners of more than 5% of CMMB shares.

Who are the key reporting persons in CMMB's Schedule 13D/A filing?

The key reporting persons are OrbiMed Israel BioFund GP Limited Partnership, OrbiMed Israel GP Ltd., Erez Chimovits (Israeli citizen), and Carl L. Gordon (U.S. citizen). They collectively share voting and dispositive power over the reported shares.

What was the major transaction that triggered CMMB's Schedule 13D/A filing?

The triggering transaction was OrbiMed Israel Partners' (OIP) sale of 1,610,000 American Depositary Shares (ADSs) at a price of $1.10 per ADS on June 18, 2025, which reduced their ownership below the 5% reporting threshold.

What are the current investment intentions of OrbiMed regarding CMMB stock?

The filing states that OrbiMed will continue to review their investment based on various factors including CMMB's business condition, financial results, and market conditions. They may acquire additional shares or dispose of current holdings either through open market or private transactions depending on these factors.