Centessa Pharmaceuticals (NASDAQ: CNTA) Medicxi group now reports 0% ownership

Rhea-AI Filing Summary

Centessa Pharmaceuticals plc is the subject of an amended Schedule 13G filing in which a group of affiliated investment entities managed by Medicxi report their current ownership position. The filing covers several Jersey-based limited partnerships and limited companies, collectively referred to as the Medicxi Funds and related managing entities.

As of June 30, 2026, the Reporting Persons state that they beneficially own 0 Ordinary Shares of Centessa Pharmaceuticals plc, representing 0.0% of the outstanding class. They also report having no sole or shared power to vote or dispose of any Ordinary Shares. The certification section is executed on behalf of each Reporting Person by Francois Chesnay in various director and manager capacities.

Key Figures

Beneficial ownership: 0 Ordinary Shares Ownership percentage: 0.0% Sole voting power: 0 +3 more

6 metrics

Beneficial ownership 0 Ordinary Shares Beneficially owned by all Reporting Persons as of June 30, 2026

Ownership percentage 0.0% Percent of class of Centessa Ordinary Shares as of June 30, 2026

Sole voting power 0 Number of shares over which Reporting Persons have sole power to vote

Shared voting power 0 Number of shares over which Reporting Persons have shared power to vote

Sole dispositive power 0 Number of shares over which Reporting Persons have sole dispositive power

Shared dispositive power 0 Number of shares over which Reporting Persons have shared dispositive power

Key Terms

beneficially own, sole power to vote, shared power to vote, sole power to dispose, +2 more

6 terms

beneficially own regulatory

"none of the Reporting Persons may be deemed to beneficially own any Ordinary Shares"

Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.

sole power to vote regulatory

"Number of shares as to which the person has | (i) Sole power to vote"

shared power to vote regulatory

"(ii) Shared power to vote or to direct the vote: 0"

sole power to dispose regulatory

"(iii) Sole power to dispose or to direct the disposition of: 0"

shared power to dispose regulatory

"(iv) Shared power to dispose or to direct the disposition of: 0"

Reporting Persons regulatory

"are sometimes individually referred to herein as a "Reporting Person" and collectively as the "Reporting Persons""

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Available on EDGAR 08/04/2026 - 11:41 AM Accepted by SEC EDGAR 08/04/2026 - 11:41 AM Learn about SEC filing dates

FAQ

What does the Schedule 13G/A filing report for Centessa Pharmaceuticals (CNTA)?

The filing reports that the Medicxi-affiliated Reporting Persons beneficially own 0 Ordinary Shares of Centessa Pharmaceuticals, representing 0.0% of the class as of June 30, 2026, with no voting or dispositive power over any shares.

Who are the Reporting Persons in the Centessa (CNTA) Schedule 13G/A?

The Reporting Persons include multiple Jersey entities, such as Medicxi Growth I LP, Medicxi Ventures I LP, Medicxi Secondary I LP, their related co-invest and GP entities, and Medicxi Ventures Management (Jersey) Limited as manager of the Medicxi Funds.

What ownership percentage do the Medicxi Funds report in Centessa (CNTA)?

The Medicxi Funds and related entities report owning 0.0% of Centessa’s Ordinary Shares as of June 30, 2026. They list 0 shares beneficially owned and no sole or shared power to vote or dispose of any shares.

What class of securities is covered for Centessa (CNTA) in this Schedule 13G/A?

The filing covers Ordinary Shares of Centessa Pharmaceuticals plc with a nominal value of 0.002 per share, identified by CUSIP 152309100. The Reporting Persons state they have no beneficial ownership of this class.

What is the as-of date for the ownership information in the Centessa (CNTA) Schedule 13G/A?

The ownership information is stated as of June 30, 2026. As of that date, the Reporting Persons report 0 shares beneficially owned, corresponding to 0.0% of the outstanding Ordinary Shares of Centessa Pharmaceuticals.

Who signed the Centessa (CNTA) Schedule 13G/A on behalf of the Reporting Persons?

The filing is signed by Francois Chesnay in multiple capacities, including Director and Director of Manager for the relevant Medicxi entities, with signature dates of August 4, 2026 for each signature block.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 2)

Centessa Pharmaceuticals plc

(Name of Issuer)

Ordinary Shares, nominal value 0.002 per share

(Title of Class of Securities)

152309100

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Growth I LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Growth Co-Invest I LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Growth I GP Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Ventures I LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Co-Invest I LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Ventures I GP Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Secondary I LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Secondary Co-Invest I LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Secondary I GP Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP Number(s): 152309100

1

Names of Reporting Persons

Medicxi Ventures Management (Jersey) Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

JERSEY

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

0.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.0 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Centessa Pharmaceuticals plc
(b)	Address of issuer's principal executive offices: 3rd Floor, 1 Ashley Road, Altrincham Cheshire WA14 2DT United Kingdom
Item 2.
(a)	Name of person filing: (i) Medicxi Growth I LP ("Growth I"), a Jersey limited partnership; (ii) Medicxi Growth Co-Invest I LP ("Growth Co-Invest I"), a Jersey limited partnership; (iii) Medicxi Growth I GP Limited ("Growth I GP"), a Jersey limited liability company, which is the sole managing general partner of Growth I and Growth Co-Invest I; (iv) Medicxi Ventures I LP ("Ventures I"), a Jersey limited partnership; (v) Medicxi Co-Invest I LP ("Co-Invest I"), a Jersey limited partnership; (vi) Medicxi Ventures I GP Limited ("Ventures I GP"), a Jersey limited liability company, which is the sole managing general partner of Ventures I and Co-Invest I; (vii) Medicxi Secondary I LP ("Secondary I"), a Jersey limited partnership; (viii) Medicxi Secondary Co-Invest I LP ("Secondary Co-Invest I" and, together with Growth I, Growth Co-Invest I, Ventures I, Co-Invest I and Secondary I, the "Medicxi Funds"), a Jersey limited partnership; (ix) Medicxi Secondary I GP Limited ("Secondary I GP"), a Jersey limited liability company, which is the sole managing general partner of Secondary I and Secondary Co-Invest I; and (x) Medicxi Ventures Management (Jersey) Limited ("Medicxi Manager"), a Jersey limited liability company, which is the sole manager of the Medicxi Funds. Growth I, Growth Co-Invest I, Growth I GP, Ventures I, Co-Invest I, Ventures I GP, Secondary I, Secondary Co-Invest I, Secondary I GP and Medicxi Manager are sometimes individually referred to herein as a "Reporting Person" and collectively as the "Reporting Persons."
(b)	Address or principal business office or, if none, residence: The address of the principal business office of each of the Reporting Persons is c/o CSC Fund Services (Jersey) Limited, 44 Esplanade, St. Helier, Jersey JE4 9WG.
(c)	Citizenship: See Item 2(a).
(d)	Title of class of securities: Ordinary Shares, nominal value 0.002 per share
(e)	CUSIP No.: 152309100
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: As of June 30, 2026, none of the Reporting Persons may be deemed to beneficially own any Ordinary Shares of the Issuer.
(b)	Percent of class: 0.0 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.	Certifications:
	Not Applicable

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Medicxi Growth I LP

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director of Manager
Date:	08/04/2026

Medicxi Growth Co-Invest I LP

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director of Manager
Date:	08/04/2026

Medicxi Growth I GP Limited

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director
Date:	08/04/2026

Medicxi Ventures I LP

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director of Manager
Date:	08/04/2026

Medicxi Co-Invest I LP

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director of Manager
Date:	08/04/2026

Medicxi Ventures I GP Limited

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director
Date:	08/04/2026

Medicxi Secondary I LP

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director of Manager
Date:	08/04/2026

Medicxi Secondary Co-Invest I LP

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director of Manager
Date:	08/04/2026

Medicxi Secondary I GP Limited

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director
Date:	08/04/2026

Medicxi Ventures Management (Jersey) Limited

Signature:	/s/ Francois Chesnay
Name/Title:	Francois Chesnay, Director
Date:	08/04/2026